^aState Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China

^bKey Laboratory of Alkene-carbon Fibres-based Technology & Application for Detection of Major Infectious Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, Cancer Institute, Suzhou Medical College, Soochow University, Suzhou 215127, China

^cThe First Central Clinical College, Tianjin Medical University, Tianjin 300192, China

^dDepartment of Hematology, Tianjin First Central Hospital, Tianjin 300192, China

^eDepartment of Dermatology, Duke University School of Medicine, Durham, NC 27710, USA

^fDepartment of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA

^gSuzhou Key Laboratory of Pathogen Bioscience and Anti-infective Medicine, Jiangsu Province Engineering Research Center of Precision Diagnostics and Therapeutics Development, Suzhou Medical College, Soochow University, Suzhou 215127, China

^hNational Center of Technology Innovation for Biopharmaceuticals, Suzhou Biomedical Industry Innovation Center, Suzhou 215127, China