Acta Pharmaceutica Sinica B

Acta Pharmaceutica Sinica B ›› 2025, Vol. 15 ›› Issue (2) : 707 - 721. DOI: 10.1016/j.apsb.2024.05.022

ORIGINAL ARTICLE

Safety, dosimetry, and efficacy of an optimized long-acting somatostatin analog for peptide receptor radionuclide therapy in metastatic neuroendocrine tumors: From preclinical testing to first-in-human study

Wei Guo ^a^,^b ,
Xuejun Wen ^c ,
Yuhang Chen ^b ,
Tianzhi Zhao ^d^,^e^,^f ,
Jia Liu ^c ,
Yucen Tao ^d^,^e^,^f ,
Hao Fu ^a ,
Hongjian Wang ^b ,
Weizhi Xu ^a ,
Yizhen Pang ^a ,
Liang Zhao ^a ,
Jingxiong Huang ^a ,
Pengfei Xu ^d^,^e^,^f ,
Zhide Guo ^c ,
Weibing Miao ^g^,^h^,ⁱ^,^* ,
Jingjing Zhang ^d^,^e^,^f^,^* ,
Xiaoyuan Chen ^d^,^e^,^f^,^* ,
Haojun Chen ^a^,^b^,^*

Author information +

^aDepartment of Nuclear Medicine and Minnan PET Center, Xiamen Key Laboratory of Radiopharmaceuticals, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen 361102, China

^bSchool of Clinical Medicine, Fujian Medical University, Fuzhou 350005, China

^cState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen 361102, China

^dDepartments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore 138667, Singapore

^eClinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 138667, Singapore

^fNanomedicine Translational Research Program, NUS Center for Nanomedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 138667, Singapore

^gDepartment of Nuclear Medicine, the First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China

^hDepartment of Nuclear Medicine, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350212, China

ⁱFujian Key Laboratory of Precision Medicine for Cancer, the First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China

^* Corresponding authors.

收起

Received	Accepted	Published
2024-02-28	2024-05-09
Issue Date
2026-09-17

Accesses

Total: 10

	Just accepted	Online first	Issue	Totals
HTML pages views	0	0	6	6
PDF downloads	0	0	4	4

Accesses in the last 12 months

Accesses come from

Citations

Citation counts are provided from Web of Science and CrossRef. The counts may vary by service, and are reliant on the availability of their data. Counts will update daily once available.

Search

Online attention

The hierarchy quorum sensing network in Pseudomonas aeruginosa

Full Text HTML

PDF (624KB)

Recommended