The PGAM5–NEK7 interaction is a therapeutic target for NLRP3 inflammasome activation in colitis
aState Key Laboratory of Natural Medicines, New Drug Screening Center, Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education), China Pharmaceutical University, Nanjing 210009, China
bCollege of Basic Medical Sciences, Dalian Medical University, Dalian 116044, China
cHelmholtz International Laboratory, State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China
dJiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Pharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, China
eInstitute of Pathology & Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China
fState Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210023, China
* Corresponding authors.
收起