Acta Pharmaceutica Sinica B

Acta Pharmaceutica Sinica B ›› 2025, Vol. 15 ›› Issue (3) : 1552 - 1570. DOI: 10.1016/j.apsb.2024.12.037

ORIGINAL ARTICLE

BRD4 regulates m⁶A of ESPL1 mRNA via interaction with ALKBH5 to modulate breast cancer progression

Haisheng Zhang ^a ,
Linlin Lu ^b ,
Cheng Yi ^a ,
Tao Jiang ^a^,^c ,
Yunqing Lu ^a ,
Xianyuan Yang ^a ,
Ke Zhong ^a ,
Jiawang Zhou ^a ,
Jiexin Li ^a ,
Guoyou Xie ^a ,
Zhuojia Chen ^d ,
Zongpei Jiang ^e ,
Gholamreza Asadikaram ^f ,
Yanxi Peng ^g^,^* ,
Dan Zhou ^h^,^* ,
Hongsheng Wang ^a^,^*

Author information +

^aGuangdong Provincial Key Laboratory of Chiral Molecule and Drug Discovery; State Key Laboratory of Anti-Infective Drug Discovery and Development; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China

^bInstitute of Medical Sciences, the Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250033, China

^cSchool of Life Sciences, Zhuhai College of Science and Technology, Zhuhai 519041, China

^dSun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China

^eDepartment of Nephrology, the Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510655, China

^fEndocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Medical University Campus, Kerman 7616914115, Iran

^gSchool of Public Health, Xiangnan University, Chenzhou 423000, China

^hDepartment of Breast Surgery, the First People's Hospital of Foshan, Foshan 528100, China

^* Corresponding authors.

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Received	Accepted	Published
2024-06-25	2024-11-15
Issue Date
2026-09-17

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