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Identification of HMGB1 as a target of 3-O-benzoyl-20-deoxyingenol in NSCLC therapy using integrated ABPP and SIP
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Acta Pharmaceutica Sinica B | 2026, 16(4) : 2587 - 2592
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Acta Pharmaceutica Sinica B | 2026, 16(4): 2587-2592
• Letter to the Editor •
Identification of HMGB1 as a target of 3-O-benzoyl-20-deoxyingenol in NSCLC therapy using integrated ABPP and SIP
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Yaxu Wang1,2, Yan Liu1, Yuan Zhuang1,2, Wennan Luo2, Lu Pan1,2, Liwei Gu2, Jigang Wang1,2, Qingbo Liu1, Shao-Jiang Song1
Affiliations
    1 Key Laboratory of Computational Chemistry Based Natural Antitumor Drug Research & Development, Liaoning Province, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;
    2 State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Artemisinin Research Center, and Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China
doi: 10.1016/j.apsb.2026.01.043
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NSCLC  /  3-O-Benzoyl-20-deoxyingenol  /  HMGB1  /  Autophagy-mediated apoptosis  /  Immunogenic cell death
Yaxu Wang, Yan Liu, Yuan Zhuang, Wennan Luo, Lu Pan, Liwei Gu, Jigang Wang, Qingbo Liu, Shao-Jiang Song. Identification of HMGB1 as a target of 3-O-benzoyl-20-deoxyingenol in NSCLC therapy using integrated ABPP and SIP[J]. Acta Pharmaceutica Sinica B, 2026 , 16 (4) : 2587 -2592 . DOI: 10.1016/j.apsb.2026.01.043
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Year 2026 volume 16 Issue 4
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doi: 10.1016/j.apsb.2026.01.043
  • Receive Date：2025-08-11
  • Online Date：2026-09-17
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  • Received：2025-08-11
  • Revised：2025-11-16
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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