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AT-17 redefines local anesthetics by targeting mitochondrial apoptosis
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Acta Pharmaceutica Sinica B | 2025, 15(11) : 6087 - 6088
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Acta Pharmaceutica Sinica B | 2025, 15(11): 6087-6088
• Commentaries •
AT-17 redefines local anesthetics by targeting mitochondrial apoptosis
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Xiaoyuan Chen1,2,3,4,5,6,7,8
Affiliations
    1 Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119074, Singapore;
    2 Department of Chemical and Biomolecular Engineering, College of Design and Engineering, National University of Singapore, Singapore 117575, Singapore;
    3 Department of Biomedical Engineering, College of Design and Engineering, National University of Singapore, Singapore 117575, Singapore;
    4 Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore 117544, Singapore;
    5 Clinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore;
    6 Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore;
    7 Theranostics Center of Excellence (TCE), Yong Loo Lin School of Medicine, National University of Singapore, Singapore 138667, Singapore;
    8 Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research (A*STAR), Singapore 138673, Singapore
doi: 10.1016/j.apsb.2025.10.013
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Oral local anesthetics  /  Articaine  /  Mitochondria  /  Apoptosis
Xiaoyuan Chen. AT-17 redefines local anesthetics by targeting mitochondrial apoptosis[J]. Acta Pharmaceutica Sinica B, 2025 , 15 (11) : 6087 -6088 . DOI: 10.1016/j.apsb.2025.10.013
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Year 2025 volume 15 Issue 11
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doi: 10.1016/j.apsb.2025.10.013
  • Online Date：2026-09-17
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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