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APOE2 reduces risk of Alzheimer's disease by protection of lysosomes from lipid overloading
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Acta Pharmaceutica Sinica B | 2025, 15(8) : 4306 - 4308
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Acta Pharmaceutica Sinica B | 2025, 15(8): 4306-4308
• Highlights •
APOE2 reduces risk of Alzheimer's disease by protection of lysosomes from lipid overloading
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Jing Feng1, Xiwen Ma1, Jianping Ye1,2
Affiliations
    1 Institute of Trauma and Metabolism, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou 450007, China;
    2 Tianjian Laboratory of Advanced Biomedical Sciences, Academy of Medical Sciences, Zhengzhou University, Zhengzhou 450001, China
doi: 10.1016/j.apsb.2025.03.001
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APOE2  /  APOE3  /  APOE4  /  Lipofuscin  /  LDLR  /  Alzheimer's disease
Jing Feng, Xiwen Ma, Jianping Ye. APOE2 reduces risk of Alzheimer's disease by protection of lysosomes from lipid overloading[J]. Acta Pharmaceutica Sinica B, 2025 , 15 (8) : 4306 -4308 . DOI: 10.1016/j.apsb.2025.03.001
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Year 2025 volume 15 Issue 8
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doi: 10.1016/j.apsb.2025.03.001
  • Receive Date：2025-01-15
  • Online Date：2026-09-17
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  • Received：2025-01-15
  • Revised：2025-03-02
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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