Home Journals Articles Updates About
CN
image
收藏切换
Potential oncogenic risks of Keap1-targeting PROTACs: Caution warranted in drug design
收藏切换
PDF
Acta Pharmaceutica Sinica B | 2026, 16(6) : 3985 - 3987
Less
收藏切换
Acta Pharmaceutica Sinica B | 2026, 16(6): 3985-3987
• Commentaries •
Potential oncogenic risks of Keap1-targeting PROTACs: Caution warranted in drug design
Full
Zhe Zhao1,2, Wen Ma3, Jincen Hao4, Gaofei Hu4, Xinfeng Wang5,6
Affiliations
    1 Department of Pharmacy, Peking University Third Hospital, Beijing 100191, China;
    2 Institute for Drug Evaluation, Peking University Health Science Center, Beijing 100191, China;
    3 School of Basic Medicine, Qingdao University, Qingdao, Shandong 266071, China;
    4 The Institute of Cardiovascular Sciences and Institute of Systems Biomedicine, School of Basic Medical Sciences, State Key Laboratory of Vascular Homeostasis and Remodeling, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Beijing Key Laboratory of Cardiovascular Receptors Research, Health Science Center, Peking University, Beijing 100191, China;
    5 Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China;
    6 State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
doi: 10.1016/j.apsb.2026.03.040
Outline
收藏切换
Keap1  /  Nrf2  /  homoPROTAC  /  Redox homeostasis  /  Oncogenesis
Zhe Zhao, Wen Ma, Jincen Hao, Gaofei Hu, Xinfeng Wang. Potential oncogenic risks of Keap1-targeting PROTACs: Caution warranted in drug design[J]. Acta Pharmaceutica Sinica B, 2026 , 16 (6) : 3985 -3987 . DOI: 10.1016/j.apsb.2026.03.040
Appendix
Less
Year 2026 volume 16 Issue 6
PDF
8
5
Cite this Article
BibTeX
Article Info
doi: 10.1016/j.apsb.2026.03.040
  • Receive Date：2025-11-13
  • Online Date：2026-09-17
Article Data
Affiliations
History
  • Received：2025-11-13
  • Revised：2026-02-25
Affiliations
References
Share
https://castjournals.cast.org.cn/joweb/apsb/EN/10.1016/j.apsb.2026.03.040
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House