Home Journals Articles Updates About
CN
image
收藏切换
Piglet growth performance improved by dietary supplementation of porous or nano particles of zinc oxide may be related to the gut microbiota
收藏切换
PDF
Lina Longa, Xichen Zhaoc, *, Jie Chend, Zixi Wanga, Yanfang Tanga, Jian Huanga, Yulong Yinb, *
Animal Nutrition | 2023, 15(1) : 159 - 172
Less
收藏切换
Animal Nutrition | 2023, 15(1): 159-172
• Original Research Article •
Piglet growth performance improved by dietary supplementation of porous or nano particles of zinc oxide may be related to the gut microbiota
Full
Lina Longa, Xichen Zhaoc, *, Jie Chend, Zixi Wanga, Yanfang Tanga, Jian Huanga, Yulong Yinb, *
Affiliations
  • aSchool of Life Science and Engineering, Foshan University, Foshan 528231, China
  • bKey Laboratory for Agro-Ecological Processes in Subtropical Region, Hunan Research Center of Livestock and Poultry Sciences, South Central Experimental Station of Animal Nutrition and Feed Science in the Ministry of Agriculture, Institute of Subtropical Agriculture, the Chinese Academy of Sciences, Changsha 410125, China
  • cGuangdong Laboratory of Lingnan Modern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou 510642, China
  • dFoshan Guangmuxing Feed Co., Ltd, Foshan 528000, China
Published: 2023-12-10 doi: 10.1016/j.aninu.2023.08.011
Outline
收藏切换

Previous studies on porous or nano particles zinc oxide (ZnO) in the piglets have mainly focused on growth performance and intestinal inflammation, but have scarcely explored the efficacy on gut microbiota. In addition, the efficacy of nano particles ZnO, which is related to its product quality, remains undefined. This study aimed to determine the efficacy of dietary 500mg/kg porous or nano particles ZnO on the growth performance and gut microbiota of the weaned piglets. A total of 128 weaned piglets were randomly assigned to the dietary groups: NC (basal diet), PC (basal diet + 3,000mg/kg conventional ZnO), 500HiZ (basal diet + 500mg/kg porous particles ZnO), and 500ZNP (basal diet + 500mg/kg nano particles ZnO). Compared with the NC diet group, both 500HiZ and 500ZNP increased (P < 0.05) average daily feed intake (1 to 28d) and average daily gain (1 to 28d), and the 500ZNP tended to decrease feed to gain ratio (F:G ratio, 1 to 28 d) (P = 0.09). Both 500HiZ and 500ZNP decreased crypt depth of the ileum and increased claudin-2 in the duodenum and zonula occludens-1 in the ileum (P < 0.05). Moreover, both 500HiZ and 500ZNP decreased IL-1β and tumor necrosis factor-a (TNF-a) in the jejunum and decreased TNF-α and IL-6 in the ileum (P < 0.05). Both 500HiZ and 500ZNP increased microbial β-diversity index in the ileum and microbial α-diversity indices in the colon of piglets (P < 0.05). The probiotic genera Coprococcus (500ZNP) and Blautia (500HiZ) were positively correlated with the F:G ratio (1 to 28 d) in colon of piglets (P < 0.05). In addition, 500HiZ promoted mitochondrial fusion protein 1 (MFN1) and zinc transporter-1 (ZnT-1) in the jejunum (P < 0.05), whilst 500ZNP decreased MFN1 in the jejunum and ZnT-1 in the ileum (P < 0.05). In summary, both 500HiZ and 500ZNP improved the growth performance of piglets, which is likely via the genera Blautia and Coprococcus, respectively. Both 500HiZ and 500ZNP improved barrier function and inflammation of the intestine, and 500HiZ achieved better efficacy than 500ZNP on intestine mitochondrial functions.

Growth performance  /  Inflammation  /  Intestine morphology  /  Microbiota  /  Piglet  /  Zinc oxide
Lina Long, Xichen Zhao, Jie Chen, Zixi Wang, Yanfang Tang, Jian Huang, Yulong Yin. Piglet growth performance improved by dietary supplementation of porous or nano particles of zinc oxide may be related to the gut microbiota[J]. Animal Nutrition, 2023 , 15 (1) : 159 -172 . DOI: 10.1016/j.aninu.2023.08.011
Full Text
Less
Appendix
Less
Year 2023 volume 15 Issue 1
PDF
20
6
Cite this Article
BibTeX
Article Info
doi: 10.1016/j.aninu.2023.08.011
  • Receive Date：2022-12-15
  • Online Date：2026-02-03
  • Published：2023-12-10
Article Data
Affiliations
History
  • Received：2022-12-15
  • Revised：2023-08-22
  • Accepted：2023-08-29
Affiliations
    aSchool of Life Science and Engineering, Foshan University, Foshan 528231, China
    bKey Laboratory for Agro-Ecological Processes in Subtropical Region, Hunan Research Center of Livestock and Poultry Sciences, South Central Experimental Station of Animal Nutrition and Feed Science in the Ministry of Agriculture, Institute of Subtropical Agriculture, the Chinese Academy of Sciences, Changsha 410125, China
    cGuangdong Laboratory of Lingnan Modern Agriculture, College of Animal Science, South China Agricultural University, Guangzhou 510642, China
    dFoshan Guangmuxing Feed Co., Ltd, Foshan 528000, China

Corresponding:

* Corresponding authors.E-mail addresses: (X. Zhao)
(Y. Yin).
References
Share
https://castjournals.cast.org.cn/joweb/aninu/EN/10.1016/j.aninu.2023.08.011
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House