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Rhizoma Atractylodis: a review on processing, chemical composition, pharmacological effects, and product development
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Chang Ke1, Linghang Qu1, 2, Yanju Liu1, 2, Yi Xia3, *, Chunli Wang2, 4, *, Kang Xu1, 2, *
Acupuncture and Herbal Medicine | 2025, 5(1) : 115 - 130
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Acupuncture and Herbal Medicine | 2025, 5(1): 115-130
• Hundred of herbs •
Rhizoma Atractylodis: a review on processing, chemical composition, pharmacological effects, and product development
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Chang Ke1, Linghang Qu1, 2, Yanju Liu1, 2, Yi Xia3, *, Chunli Wang2, 4, *, Kang Xu1, 2, *
Affiliations
  • 1School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China
  • 2Hubei Shizhen Laboratory, Wuhan, China
  • 3Hubei University of Chinese Medicine, Huangjiahu Hospital, Wuhan, China
  • 4School of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, China
About Author:

Chang Ke and Linghang Qu contributed equally to this work.

Published: 2025-03-25 doi: 10.1097/HM9.0000000000000146
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Rhizoma Atractylodis has a long history of medicinal use, a broad spectrum of applications, and diverse clinical utility. This review provides a comprehensive overview of Rhizoma Atractylodis, focusing on its processing, chemical composition, pharmacological effects, and product development. Processing methods include stir-frying with bran, stir-frying until cooked, and rinsing with rice-washed water. The chemical composition includes terpenes, alkynes, sugars and their glycosides, organic acids and their esters, coumarins, and other compounds. Its pharmacological effects include the treatment of gastrointestinal diseases, arthritis, liver diseases, lung diseases, cancer, cardiovascular conditions, etc. Finally, product development prospects include decoction-ready products, Chinese patent medicines, health products and daily necessities, epidemic prevention, and veterinary medicine. Notably, this review simultaneously discusses, analyzes, and explores the quality control and industrial development of Rhizoma Atractylodis, offering guidance for advancing related industries, enhancing production quality control, and exploring innovative strategies for the clinical application and development of new Rhizoma Atractylodis-based products.

Active ingredient  /  Chinese patent drug  /  Pharmacological activity  /  Processing  /  Rhizoma Atractylodis
Chang Ke, Linghang Qu, Yanju Liu, Yi Xia, Chunli Wang, Kang Xu. Rhizoma Atractylodis: a review on processing, chemical composition, pharmacological effects, and product development[J]. Acupuncture and Herbal Medicine, 2025 , 5 (1) : 115 -130 . DOI: 10.1097/HM9.0000000000000146
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Funding
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  • Hubei Provincial Natural Science Foundation of China(2023AFD154)
  • Wuhan Municipal Health Scientific Research Fund(WZ24Z22)
Appendix
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Year 2025 volume 5 Issue 1
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5
1
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Article Info
doi: 10.1097/HM9.0000000000000146
  • Receive Date：2024-11-14
  • Online Date：2026-11-04
  • Published：2025-03-25
Article Data
Affiliations
History
  • Received：2024-11-14
  • Accepted：2025-02-10
Funding
Hubei Provincial Natural Science Foundation of China(2023AFD154)
Wuhan Municipal Health Scientific Research Fund(WZ24Z22)
Affiliations
    1School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China
    2Hubei Shizhen Laboratory, Wuhan, China
    3Hubei University of Chinese Medicine, Huangjiahu Hospital, Wuhan, China
    4School of Laboratory Medicine, Hubei University of Chinese Medicine, Wuhan, China

Corresponding:

* Yi Xia, E-mail: ;
Chunli Wang, E-mail: ;
Kang Xu, E-mail: .
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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