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Panax notoginseng polysaccharides: a review focusing on the extraction, isolation, structural characterization, biological activities, and applications
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Jiaqi Huang1, 2, Yuheng Zhao1, 2, Mengyao Wang1, 2, Xiaojin Tian1, 2, Dianxin Cui1, 2, Qilong Wang1, 2, Xue Li1, 2, *, Honghua Wu1, 2, *, Wenzhi Yang1, 2, *
Acupuncture and Herbal Medicine | 2025, 5(1) : 23 - 35
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Acupuncture and Herbal Medicine | 2025, 5(1): 23-35
• Review Articles •
Panax notoginseng polysaccharides: a review focusing on the extraction, isolation, structural characterization, biological activities, and applications
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Jiaqi Huang1, 2, Yuheng Zhao1, 2, Mengyao Wang1, 2, Xiaojin Tian1, 2, Dianxin Cui1, 2, Qilong Wang1, 2, Xue Li1, 2, *, Honghua Wu1, 2, *, Wenzhi Yang1, 2, *
Affiliations
  • 1National Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, China
  • 2Haihe Laboratory of Modern Chinese Medicine, Tianjin, China
About Author:

Jiaqi Huang, Yuheng Zhao, and Mengyao Wang contributed equally to this work.

Published: 2025-03-25 doi: 10.1097/HM9.0000000000000144
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Panax notoginseng is a traditional Chinese medicine containing various constituents, including the saponins, polysaccharides, polyacetylenes, amino acids, etc. It has beneficial functions, such as the anti-inflammatory, antitumor, hepatoprotective, and anti-aging effects. Among these, P. notoginseng polysaccharides (PNPs) have been exploited because of their extensive pharmacological effects, being ranked as one of the current research hotspots, especially for the functional foods and medical practice. In this review, the literature related to PNPs in the past 20 years was surveyed and analyzed using both the China National Knowledge Infrastructure (CNKI) and Web of Science (WOS) databases. The visualization diagram shows that current studies on PNPs mainly focus on the antioxidant and immunomodulatory activities and structural characterization. In addition, the extraction, separation, purification, chemical analysis, structural characteristics, bioactivities, and applications of PNPs are outlined, in detail, aimed to provide valuable information for the further study, development, and utilization regarding PNPs.

Biological activity  /  Extraction  /  Isolation  /  Panax notoginseng polysaccharides  /  Structural characterization
Jiaqi Huang, Yuheng Zhao, Mengyao Wang, Xiaojin Tian, Dianxin Cui, Qilong Wang, Xue Li, Honghua Wu, Wenzhi Yang. Panax notoginseng polysaccharides: a review focusing on the extraction, isolation, structural characterization, biological activities, and applications[J]. Acupuncture and Herbal Medicine, 2025 , 5 (1) : 23 -35 . DOI: 10.1097/HM9.0000000000000144
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Funding
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  • National Key R&D Program of China(2022YFC3501805)
  • Science and Technology Program of Tianjin in China(23ZYJDSS00030)
  • National Natural Science Foundation of China(82374030)
  • Science & Technology Development Fund of Tianjin Education Commission for Higher Education(2021KJ127)
  • Tianjin Outstanding Youth Fund(23JCJQJC00030)
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Year 2025 volume 5 Issue 1
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Article Info
doi: 10.1097/HM9.0000000000000144
  • Receive Date：2024-04-09
  • Online Date：2026-11-04
  • Published：2025-03-25
Article Data
Affiliations
History
  • Received：2024-04-09
  • Accepted：2025-01-22
Funding
National Key R&D Program of China(2022YFC3501805)
Science and Technology Program of Tianjin in China(23ZYJDSS00030)
National Natural Science Foundation of China(82374030)
Science & Technology Development Fund of Tianjin Education Commission for Higher Education(2021KJ127)
Tianjin Outstanding Youth Fund(23JCJQJC00030)
Affiliations
    1National Key Laboratory of Chinese Medicine Modernization, Tianjin University of Traditional Chinese Medicine, Tianjin, China
    2Haihe Laboratory of Modern Chinese Medicine, Tianjin, China

Corresponding:

* Xue Li, E-mail: ;
Honghua Wu, E-mail: ;
Wenzhi Yang, E-mail: .
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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