Article(id=1322906946872943440, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322887411688919265, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1626364800000, acceptedDateStr=2021-07-16, onlineDate=1793335194557, onlineDateStr=2026-10-30, pubDate=1636905600000, pubDateStr=2021-11-15, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793335194557, onlineIssueDateStr=2026-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793335194557, creator=13701087609, updateTime=1793335194557, updator=13701087609, issue=Issue{id=1322887411688919265, tenantId=1146029695717560320, journalId=1235980733773295621, year='2021', volume='30', issue='21', pageStart='1921', pageEnd='2016', issueExtLink='null', onlineDate='null', pubDate='1636905600000', pubDateStr='2021-11-15', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1793330537006, creator='13701087609', updateTime=1793337443794, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322916380919608076, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322887411688919265, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322916380919608077, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322887411688919265, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=2009, endPage=2016, ext={EN=ArticleExt(id=1322906948701659985, articleId=1322906946872943440, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Mini health technology assessment of four antiangiogenic agents for advanced NSCLC, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective:

To provide a basis for drug selection, as well as safe and rational use of drugs, Mini health technology assessment was used for 4 antiangiogenic agents for the treatment of advanced NSCLC (bevacizumab, ramucirumab, anlotinib, recombinant human endostatin).

Methods:

Mini health technology assessment was conducted for the 4 mentioned antiangiogenic agents based on ten aspects, such as pharmaceutical characteristics, effectiveness, safety, economy, medical insurance, national essential drug, storage conditions, expiration date, global use and corporate credibility.

Results:

Based on the above evaluation criteria, the scores of the four antiangiogenic agents ranged 61~72. The difference in scores was mainly in terms of effectiveness, safety, economy, and storage conditions. Arotinib scored high in the treatment of small cell lung cancer, and was recommended in the drug selection list of medical institutions.

Conclusion:

Mini health technology assessment is a multi-dimensional evaluation of drugs, providing basis for hospital drug selection, safe and rational use. It is of relatively high promotion value.

, authors=Bing-nan REN, Chao-jun XUE, Xiao LI, Yue ZHAO, Zhan-jun DONG, authorsList=Bing-nan REN, Chao-jun XUE, Xiao LI, Yue ZHAO, Zhan-jun DONG, authorCompany=null, correspAuthors=Zhan-jun DONG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322906948991066962, articleId=1322906946872943440, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=4种治疗晚期非小细胞肺癌的抗血管生成药物Mini卫生技术评估, columnId=1236331163573342670, journalTitle=中国新药杂志, columnName=药物安全与合理应用, runingTitle=null, highlight=null, articleAbstract=
目的:

通过对贝伐珠单抗、雷莫芦单抗、安罗替尼、重组人血管内皮抑制素4种治疗晚期非小细胞肺癌(NSCLC)的抗血管生成药进行Mini卫生技术评估,以期为医疗机构药品遴选、药品安全合理使用提供依据。

方法:

从药学特性、有效性、安全性、经济性、医保、国家基本药物、贮藏条件、有效期、全球使用情况和企业信誉度共10个方面对4种抗血管生成药进行Mini卫生技术评估。

结果:

基于上述评估标准,4种抗血管生成药的评分在61~72分,评分差异主要在有效性、安全性、经济性、贮藏条件4个方面。安罗替尼在非小细胞肺癌治疗方面得分较高,受到推荐进入医疗机构药品遴选目录。

结论:

Mini卫生技术评估从多个纬度对药品价值进行综合评价,能为医院药品遴选、安全合理使用提供依据,有一定的推广价值。

, authors=任炳楠, 薛朝军, 李宵, 赵越, 董占军, authorsList=任炳楠, 薛朝军, 李宵, 赵越, 董占军, authorCompany=null, correspAuthors=董占军, authorNote=

任炳楠,男,硕士,主要从事医院管理研究。E-mail:。

, correspAuthorsNote=
董占军,男,硕士生导师,主要从事医院药学、药事管理研究。联系电话:(0311)85988604,E-mail:。
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任炳楠,男,硕士,主要从事医院管理研究。E-mail:。

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任炳楠,男,硕士,主要从事医院管理研究。E-mail:。

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language=CN, orderNo=3, keyword=雷莫芦单抗), Keyword(id=1322906951281156984, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322906946872943440, language=CN, orderNo=4, keyword=安罗替尼), Keyword(id=1322906951327294329, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322906946872943440, language=CN, orderNo=5, keyword=重组人血管内皮抑制素), Keyword(id=1322906953013404538, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322906946872943440, language=CN, orderNo=6, keyword=Mini卫生技术评估)], refs=[Reference(id=1322906953122456443, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322906946872943440, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[1], rfOrder=0, authorNames=null, journalName=null, refType=null, unstructuredReference=CHALKIDOU K, MARTEN R, CUTLER D, et al. 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4种治疗晚期非小细胞肺癌的抗血管生成药物Mini卫生技术评估
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任炳楠 , 薛朝军 , 李宵 , 赵越 , 董占军
中国新药杂志 | 药物安全与合理应用 2021,30(21): 2009-2016
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中国新药杂志 |药物安全与合理应用 2021 , 30 (21) : 2009 -2016
4种治疗晚期非小细胞肺癌的抗血管生成药物Mini卫生技术评估
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任炳楠 , 薛朝军, 李宵, 赵越, 董占军
作者信息
  • 河北省人民医院药学部,石家庄 050000
通讯作者:
董占军,男,硕士生导师,主要从事医院药学、药事管理研究。联系电话:(0311)85988604,E-mail:。
作者简介:

任炳楠,男,硕士,主要从事医院管理研究。E-mail:。

Mini health technology assessment of four antiangiogenic agents for advanced NSCLC
Bing-nan REN , Chao-jun XUE, Xiao LI, Yue ZHAO, Zhan-jun DONG
Affiliations
  • Department of Pharmacy, Hebei General Hospital, Shijiazhuang 050000, China
出版时间: 2021-11-15
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目的:

通过对贝伐珠单抗、雷莫芦单抗、安罗替尼、重组人血管内皮抑制素4种治疗晚期非小细胞肺癌(NSCLC)的抗血管生成药进行Mini卫生技术评估,以期为医疗机构药品遴选、药品安全合理使用提供依据。

方法:

从药学特性、有效性、安全性、经济性、医保、国家基本药物、贮藏条件、有效期、全球使用情况和企业信誉度共10个方面对4种抗血管生成药进行Mini卫生技术评估。

结果:

基于上述评估标准,4种抗血管生成药的评分在61~72分,评分差异主要在有效性、安全性、经济性、贮藏条件4个方面。安罗替尼在非小细胞肺癌治疗方面得分较高,受到推荐进入医疗机构药品遴选目录。

结论:

Mini卫生技术评估从多个纬度对药品价值进行综合评价,能为医院药品遴选、安全合理使用提供依据,有一定的推广价值。

非小细胞肺癌  /  贝伐珠单抗  /  雷莫芦单抗  /  安罗替尼  /  重组人血管内皮抑制素  /  Mini卫生技术评估
Objective:

To provide a basis for drug selection, as well as safe and rational use of drugs, Mini health technology assessment was used for 4 antiangiogenic agents for the treatment of advanced NSCLC (bevacizumab, ramucirumab, anlotinib, recombinant human endostatin).

Methods:

Mini health technology assessment was conducted for the 4 mentioned antiangiogenic agents based on ten aspects, such as pharmaceutical characteristics, effectiveness, safety, economy, medical insurance, national essential drug, storage conditions, expiration date, global use and corporate credibility.

Results:

Based on the above evaluation criteria, the scores of the four antiangiogenic agents ranged 61~72. The difference in scores was mainly in terms of effectiveness, safety, economy, and storage conditions. Arotinib scored high in the treatment of small cell lung cancer, and was recommended in the drug selection list of medical institutions.

Conclusion:

Mini health technology assessment is a multi-dimensional evaluation of drugs, providing basis for hospital drug selection, safe and rational use. It is of relatively high promotion value.

non-small cell lung cancer (NSCLC)  /  bevacizumab  /  ramucirumab  /  anlotinib  /  recombinant human endostatin  /  Mini health technology assessment
任炳楠, 薛朝军, 李宵, 赵越, 董占军. 4种治疗晚期非小细胞肺癌的抗血管生成药物Mini卫生技术评估. 中国新药杂志, 2021 , 30 (21) : 2009 -2016 .
Bing-nan REN, Chao-jun XUE, Xiao LI, Yue ZHAO, Zhan-jun DONG. Mini health technology assessment of four antiangiogenic agents for advanced NSCLC[J]. Chinese Journal of New Drugs, 2021 , 30 (21) : 2009 -2016 .

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2021年第30卷第21期
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  • 首发时间:2026-10-30
  • 出版时间:2021-11-15
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  • 录用日期:2021-07-16
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    河北省人民医院药学部,石家庄 050000

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董占军,男,硕士生导师,主要从事医院药学、药事管理研究。联系电话:(0311)85988604,E-mail:。
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2种不同金属材料的力学参数
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属
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种数
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species
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species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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