Article(id=1322906806527337260, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322887806737825858, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1630857600000, acceptedDateStr=2021-09-06, onlineDate=1793335161095, onlineDateStr=2026-10-30, pubDate=1634227200000, pubDateStr=2021-10-15, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793335161095, onlineIssueDateStr=2026-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793335161095, creator=13701087609, updateTime=1793335161095, updator=13701087609, issue=Issue{id=1322887806737825858, tenantId=1146029695717560320, journalId=1235980733773295621, year='2021', volume='30', issue='19', pageStart='1729', pageEnd='1824', issueExtLink='null', onlineDate='null', pubDate='1634227200000', pubDateStr='2021-10-15', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1793330631192, creator='13701087609', updateTime=1793337389212, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322916151994495727, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322887806737825858, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322916151994495728, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322887806737825858, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1775, endPage=1782, ext={EN=ArticleExt(id=1322906806695109421, articleId=1322906806527337260, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=The feasibility analysis of SARS-CoV-2 neutralizing antibody colloidal gold test card for the detection of neutralizing antibodies in different populations, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To compare the correlation between the results of SARS-CoV-2 neutralizing antibody colloidal gold test cards prepared by two different principles and the SARS-CoV-2 pseudovirus neutralization experiment, and to evaluate the feasibility of the neutralizing antibody colloidal gold test card for the SARS-CoV-2 neutralizing antibody detection in different populations.
Methods: Two kinds of SARS-CoV-2 neutralizing antibody colloidal gold test cards using double antigen sandwich method (manufacturer A) and competitive blocking method (manufacturers B) were used to detect the samples with SARS-CoV-2 neutralizing antibody titers. Detection sensitivity and the correlation between the two methods and the neutralization experiment were compared. The intravenous human immunoglobulin and specific immunoglobulin prepared before the outbreak of COVID-19 epidemic were detected to investigate the specificity of the eligible test card. In order to determine whether there is a hook effect, individual immunized plasma samples of high ELISA titers were tested with series of dilutions and original dilution. Single post-immunized plasma samples were detected with different ELISA titers, the positive rates were determined and the color changes were observed. Single post-immunized plasma samples were screened in the low-dilution area of ELISA according to chromaticity of 120NT50 and 300NT50 on the colorimetric card to prepare pooled plasma. The results were compared with the currently used indirect ELISA method.
Results: The detection limits of manufacturers A and B for the first-generation NIBSC international standard 20/136 (anti-SARS-CoV-2 human immunoglobulin international standard) were 0.612 5 and 5 IU·mL-1, respectively. The results of different titers of pooled plasma (both of post-immunization with SARS-CoV-2 vaccine and COVID-19 convalescence plasma) have a good correlation with the neutralizing antibody titer. The post-immunization plasma with high ELISA dilutions (above 10 000) did not show hook effect. The positive rate of individual plasma of different ELISA dilution levels reached 100% when the dilution was above 160, and the uniformity of the chromaticity was higher when the dilution level was above 640. The overall chromaticity became darker as the ELISA dilution increased. The chromaticities of Ppool 120NT50 and Ppool 300NT50 screened according to the colorimetric chart were close to the neutralizing antibody titers.
Conclusion: The correlation between the results of the manufacturer A neutralizing antibody test card using the dual antigen sandwich method to detect SARS-CoV-2 neutralizing antibody in convalescent plasma and post-immunization plasma and the titer of the pseudovirus neutralization experiment is better than that of the manufacturer B product using the competitive inhibition method and indirect ELISA. And the color brightness of the detection line is positively correlated with the level of neutralizing antibody, which can be used for preliminary screening of neutralizing antibody in different populations.
, authors=Zhi-jun ZHOU
1, Yan PENG
1, De-ming JI
1, Yong ZHANG
2, Lu FENG
1, Tao-jing LI
2, Dong-mei XIA
1, Yong HU
1, Ce-sheng LI
1, authorsList=Zhi-jun ZHOU, Yan PENG, De-ming JI, Yong ZHANG, Lu FENG, Tao-jing LI, Dong-mei XIA, Yong HU, Ce-sheng LI, authorCompany=null, correspAuthors=Yong HU, Ce-sheng LI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322906806976127790, articleId=1322906806527337260, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=新型冠状病毒中和抗体胶体金测试卡检测不同人群中和抗体的可行性分析, columnId=1236330552693944345, journalTitle=中国新药杂志, columnName=生物医药前沿, runingTitle=null, highlight=null, articleAbstract=
目的： 比较2种不同原理制备的新型冠状病毒（SARS-CoV-2）中和抗体胶体金测试卡与SARS-CoV-2假病毒中和实验的相关性，评估半定量的中和抗体胶体金测试卡用于不同人群的SARS-CoV-2中和抗体检测的可行性。
方法： 分别采用厂家A胶体金测试卡（双抗原夹心法）、厂家B胶体金测试卡（竞争阻断法）和SARS-CoV-2假病毒中和法进行检测，比较这2种胶体金方法与中和实验的相关性和敏感度；在确定了测试卡厂家后，检测新型冠状病毒肺炎（COVID-19）疫情暴发前制备的静注人免疫球蛋白及特异性免疫球蛋白，考察其特异性；对ELISA高稀释倍数新冠疫苗免疫后血浆进行原倍和稀释品检测，判断是否有hook效应；检测不同ELISA稀释倍数档位的单份免疫后血浆，判断阳性率，观察色度变化；将ELISA低稀释倍数血浆按照比色卡筛选120NT50和300NT50这2个档位血浆，制备混浆，比较胶体金测试卡与ELISA和中和抗体的相关性。
结果： 厂家A和厂家B对英国国家生物制品标准化和质量控制研究所（NIBSC）第1代国际标准品20/136（抗SARS-CoV-2人免疫球蛋白国际标准品）的检测限分别为0.612 5和5 IU·mL-1；对不同档位的混浆（新冠病毒疫苗免疫后血浆及COVID-19康复者恢复期血浆）的检测结果与中和抗体效价相关性好，检测ELISA高稀释倍数（10 000以上）新冠病毒疫苗免疫后血浆未出现hook效应；不同ELISA稀释倍数的单份血浆的阳性率在稀释倍数160以上达到100%，但是色度深浅不一，在稀释倍数640以上色度均一性较高，且色度随着ELISA稀释倍数增高整体逐渐变深。按照比色卡色度筛选的Ppool 120NT50和Ppool 300NT50与中和抗体效价接近。
结论： 采用双抗原夹心法的厂家A中和抗体测试卡检测COVID-19康复者恢复期血浆和新冠病毒疫苗免疫后血浆的结果与假病毒中和实验效价的相关性优于采用竞争抑制法的厂家B产品及间接ELISA，且检测线的色度深浅与中和抗体水平正相关，可半定量检测用于不同人群的中和抗体筛查。
, authors=周志军
1, 彭焱
1, 纪德铭
1, 张勇
2, 冯璐
1, 李陶敬
2, 夏冬梅
1, 胡勇
1, 李策生
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周志军，研究员，目前主要从事诊断试剂评估及生物制品检测方法的建立。E-mail：2586066803@qq.com。
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周志军，研究员，目前主要从事诊断试剂评估及生物制品检测方法的建立。E-mail：2586066803@qq.com。
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et al. Production of hyperimmune anti-SARS-CoV-2 intravenous immunoglobulin from pooled COVID-19 convalescent plasma[J].
Immunotherapy, 2021, 13(5): 397-407., articleTitle=null, refAbstract=null), Reference(id=1322906816732078964, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322906806527337260, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=null, journalName=null, refType=null, unstructuredReference=WANG H, ZHANG Y, HUANG B,
et al. Development of an inactivated vaccine candidate, BBIBP-CorV, with potent protection against SARS-CoV-2[J].
Cell, 2020, 182(3): 713-721, e9., articleTitle=null, refAbstract=null), Reference(id=1322906816794993525, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322906806527337260, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=null, journalName=null, refType=null, unstructuredReference=XIA S, DUAN K, ZHANG Y,
et al. Effect of an inactivated vaccine against SARS-CoV-2 on safety and immunogenicity outcomes: interim analysis of 2 randomized clinical trials[J].
JAMA, 2020, 324(10): 951-960., articleTitle=null, refAbstract=null), Reference(id=1322906816857908086, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322906806527337260, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=null, journalName=null, refType=null, unstructuredReference=XIA S, ZHANG Y, WANG Y,
et al. Safety and immunogenicity of an inactivated SARS-CoV-2 vaccine, BBIBP-CorV: a randomised, double-blind, placebo-controlled, phase 1/2 trial[J].
Lancet Infect Dis, 2021, 21(1): 39-51., articleTitle=null, refAbstract=null), Reference(id=1322906817101177719, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322906806527337260, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=null, journalName=null, refType=null, unstructuredReference=YANG F, XIAO YX, CHEN B,
et al. Development of a colloidal gold-based immunochromatographic strip test using two monoclonal antibodies to detect H7N9 avian influenza virus[J].
Virus Genes, 2020, 56(3): 396-400., articleTitle=null, refAbstract=null), Reference(id=1322906817172480888, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322906806527337260, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[6], rfOrder=5, authorNames=null, journalName=null, refType=null, unstructuredReference=周志军, 谢勇, 岳胜兰, 等. 抗新型冠状病毒抗体样本盘在其胶体金测试卡质量评价中的应用[J]. 中国生物制品学杂志, 2021, 43(1): 73-77, 83., articleTitle=null, refAbstract=null), Reference(id=1322906817247978361, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322906806527337260, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[7], rfOrder=6, authorNames=null, journalName=null, refType=null, unstructuredReference=CHEN XY, LI R, PAN ZW,
et al. Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor[J].
Cell Mol Immunol, 2020, 17(6): 647-649., articleTitle=null, refAbstract=null), Reference(id=1322906817516413818, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322906806527337260, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[8], rfOrder=7, authorNames=null, journalName=null, refType=null, unstructuredReference=MERCURIO I, TRAGNI V, BUSTO F,
et al. Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing antibodies[J].
Cell Mol Life Sci, 2021, 78(4): 1501-1522., articleTitle=null, refAbstract=null), Reference(id=1322906818992808827, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322906806527337260, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[9], rfOrder=8, authorNames=null, journalName=null, refType=null, unstructuredReference=HO M. Perspectives on the development of neutralizing antibodies against SARS-CoV-2[J].
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