Article(id=1322901653984256057, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322901641049015115, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1605628800000, acceptedDateStr=2020-11-18, onlineDate=1793333932622, onlineDateStr=2026-10-30, pubDate=1626278400000, pubDateStr=2021-07-15, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793333932622, onlineIssueDateStr=2026-10-30, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793333932622, creator=13701087609, updateTime=1793333932622, updator=13701087609, issue=Issue{id=1322901641049015115, tenantId=1146029695717560320, journalId=1235980733773295621, year='2021', volume='30', issue='13', pageStart='1153', pageEnd='1248', issueExtLink='null', onlineDate='null', pubDate='1626278400000', pubDateStr='2021-07-15', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1793333929460, creator='13701087609', updateTime=1793333989426, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322901892623376986, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322901641049015115, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322901892627571291, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322901641049015115, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1207, endPage=1212, ext={EN=ArticleExt(id=1322901654823116859, articleId=1322901653984256057, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=The research progress on new formulations of andrographolide, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Andrographolide (AG) has been found extensively pharmacological activities such as anti-inflammatory, anti-tumor, anti-virus, anti-HIV, hepatic protection, etc. However, the poor solubility with low oral bioavailability of AG limits the clinical application. New formulations of AG using advanced techniques have been developed to improve these disadvantages. In this review, we summarizes the recent advancement of AG formulation studies, providing references on novel formulation development and clinic translation of AG.

, authors=Du-juan XU^{1, 2}, Meng-ya LIU¹, Gai-zhi LIU¹, Bang-rong CAI¹, authorsList=Du-juan XU, Meng-ya LIU, Gai-zhi LIU, Bang-rong CAI, authorCompany=null, correspAuthors=Gai-zhi LIU, Bang-rong CAI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322901657335504957, articleId=1322901653984256057, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=穿心莲内酯新剂型研究进展, columnId=1236330553964810454, journalTitle=中国新药杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

穿心莲内酯具有抗炎、抗肿瘤、抗病毒、抗HIV和保肝等多种药理活性，药理活性广泛。但由于其稳定性差、水溶性和口服生物利用度低等问题限制了其临床应用，为了改善其临床应用的诸多缺陷和不足，国内外学者通过制剂的手段对穿心莲内酯的制剂新技术和新剂型进行了大量研究。本文总结了近10年来穿心莲内酯新剂型的研究进展，以期为穿心莲内酯新制剂的研发和临床转化提供参考。

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²偃师市中医院，洛阳　471900, bio={"content":"

许杜娟，女，硕士研究生，研究方向：药剂学。E-mail：1046479528@qq.com。

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许杜娟，女，硕士研究生，研究方向：药剂学。E-mail：1046479528@qq.com。

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