Article(id=1322627340631392889, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322627316266680781, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1593964800000, acceptedDateStr=2020-07-06, onlineDate=1793268531234, onlineDateStr=2026-10-29, pubDate=1611936000000, pubDateStr=2021-01-30, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793268531234, onlineIssueDateStr=2026-10-29, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793268531234, creator=13701087609, updateTime=1793268531234, updator=13701087609, issue=Issue{id=1322627316266680781, tenantId=1146029695717560320, journalId=1235980733773295621, year='2021', volume='30', issue='2', pageStart='97', pageEnd='192', issueExtLink='null', onlineDate='null', pubDate='1611936000000', pubDateStr='2021-01-30', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1793268525425, creator='13701087609', updateTime=1793269089393, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322629681875108722, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322627316266680781, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322629681879303027, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322627316266680781, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=119, endPage=124, ext={EN=ArticleExt(id=1322627340778193530, articleId=1322627340631392889, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Progress in study on hollow microneedles for transdermal drug delivery, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Hollow microneedles are similar to micron-sized needles, and have the dual characteristics of injection administration and transdermal drug delivery. Hollow microneedles as a new type of transdermal drug delivery method, have shown great potential in the delivery of biological macromolecular drugs such as vaccines and insulin in recent years. Based on domestic and foreign research reports in recent years, we reviewed the penetration mechanisms, commonly used preparation materials and processes, and its application in drug delivery systems, in order to provide references for the research and development of hollow microneedles.

, authors=Xia TIAN^{1, 2}, Ning WANG¹, Jiang-sheng DING¹, authorsList=Xia TIAN, Ning WANG, Jiang-sheng DING, authorCompany=null, correspAuthors=Ning WANG, Jiang-sheng DING, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322627341000491643, articleId=1322627340631392889, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=空心微针透皮给药技术的研究进展, columnId=1236330553964810454, journalTitle=中国新药杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

空心微针类似于微米级的注射针，具有注射给药和透皮给药的双重特点。作为一种新型的透皮给药技术，空心微针近年来在疫苗和胰岛素等生物大分子药物的递送方面显示出极大的潜力。笔者根据近年来国内外相关的研究报道，对空心微针的促透机制、常用制备材料及工艺和在透皮给药中的应用等进行归纳总结，以期为空心微针技术的研究和发展提供参考借鉴。

, authors=田霞^{1, 2}, 王宁¹, 丁江生¹, authorsList=田霞, 王宁, 丁江生, authorCompany=null, correspAuthors=王宁, 丁江生, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=《中国新药杂志》有限公司, extLink=null, articleAbsUrl=null, sourceXml=sa6vw7iJKIn2r4Qtyt/72Q==, magXml=J6iHHGne0Po4eFpO1izpQA==, pdfUrl=null, pdf=CNwooElwMqe8rW6BBmMYjw==, pdfFileSize=1288279, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=iRGreq8X0awRsIYlPTAGVA==, mapNumber=null, fund=null)}, authors=[Author(id=1322627341340230275, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322627340631392889, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=tianxiaabcd@163.com, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322627341407339142, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322627340631392889, authorId=1322627341340230275, language=EN, stringName=Xia TIAN, firstName=Xia, middleName=null, lastName=TIAN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^{1, 2}, address=¹Yunnan Institute of Materia Medica, Yunnan Bai Yao Group Innovation R&D Center, Yunnan Province Company Key Laboratory for TCM and Ethnic Drug of New Drug Creation, Kunming 650111, China
²School of Medical, Yunnan University of Business Management, Kunming 650106, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322627341474448007, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322627340631392889, authorId=1322627341340230275, language=CN, stringName=田霞, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^{1, 2}, address=¹云南省药物研究所　云南白药集团创新研发中心　云南省中药和民族药新药创制企业重点实验室，昆明　650111
²云南经济管理学院医学院，昆明　650106, bio={"content":"

田霞，女，高级工程师，主要从事药物制剂新技术研究。联系电话：（0871）68411027-8502，E-mail：tianxiaabcd@163.com。

"}, bioImg=null, bioContent=

田霞，女，高级工程师，主要从事药物制剂新技术研究。联系电话：（0871）68411027-8502，E-mail：tianxiaabcd@163.com。

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