Article(id=1322180351942841082, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322180330556076791, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1606406400000, acceptedDateStr=2020-11-27, onlineDate=1793161960826, onlineDateStr=2026-10-28, pubDate=1628956800000, pubDateStr=2021-08-15, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793161960826, onlineIssueDateStr=2026-10-28, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793161960826, creator=13701087609, updateTime=1793161960826, updator=13701087609, issue=Issue{id=1322180330556076791, tenantId=1146029695717560320, journalId=1235980733773295621, year='2021', volume='30', issue='15', pageStart='1345', pageEnd='1440', issueExtLink='null', onlineDate='null', pubDate='1628956800000', pubDateStr='2021-08-15', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=0, createTime=1793161955726, creator='13701087609', updateTime=1793162082189, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322180861076816464, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322180330556076791, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322180861076816465, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322180330556076791, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1386, endPage=1395, ext={EN=ArticleExt(id=1322180352148361979, articleId=1322180351942841082, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Research progress in pulmonary inhalation drug delivery system, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Pulmonary inhalation drug delivery has been becoming one of most popular therapy approaches due to its advantages of quick onset of action, improved efficacy and reduced adverse drug reaction. Pulmonary drug delivery system plays an extremely important role worldwide in the fields of developing new drug delivery systems, particularly in the treatment of respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma, which shows a promising prospect of clinical application. This review critically summarizes the latest classification of inhalable formulations, the US FDA-approved products on the market and the research progress of innovative products, aiming to provide broad ideas and new inspirations for the development of pulmonary inhalation formulations in the future.

, authors=Ni WAN, Bin CHEN, He LI, Wei-lun YE, Hui WANG, authorsList=Ni WAN, Bin CHEN, He LI, Wei-lun YE, Hui WANG, authorCompany=null, correspAuthors=Hui WANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322180352488100604, articleId=1322180351942841082, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=肺部吸入给药系统的研究进展, columnId=1236330553964810454, journalTitle=中国新药杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

肺部给药系统具有起效快、疗效好、同时减少不良反应等优点,已成为一种倍受关注的给药方式。在全球新型给药系统药物市场中,肺部吸入给药系统占有极为重要的地位,特别是在慢性阻塞性肺病和哮喘等与呼吸道相关疾病的治疗方面具有广泛的临床应用价值。本文将从吸入制剂的最新分类、美国FDA已上市产品情况和创新性产品研究进展等方面入手,对目前最新的吸入制剂进行综述,为今后肺部吸入制剂的研发创新提供思路和启发。

, authors=万妮, 陈斌, 李合, 叶伟伦, 王慧, authorsList=万妮, 陈斌, 李合, 叶伟伦, 王慧, authorCompany=null, correspAuthors=王慧, authorNote=

万妮,女,硕士,研究方向:创新药制剂研发。E-mail:。

, correspAuthorsNote=
王慧,女,博士生,研究方向:吸入制剂研发。联系电话:(0756)8135594,E-mail:。
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万妮,女,硕士,研究方向:创新药制剂研发。E-mail:。

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万妮,女,硕士,研究方向:创新药制剂研发。E-mail:。

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肺部吸入给药系统的研究进展
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万妮 , 陈斌 , 李合 , 叶伟伦 , 王慧
中国新药杂志 | 综述 2021,30(15): 1386-1395
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中国新药杂志 |综述 2021 , 30 (15) : 1386 -1395
肺部吸入给药系统的研究进展
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万妮 , 陈斌, 李合, 叶伟伦, 王慧
作者信息
  • 珠海市丽珠微球科技有限公司,珠海 519000
通讯作者:
王慧,女,博士生,研究方向:吸入制剂研发。联系电话:(0756)8135594,E-mail:。
作者简介:

万妮,女,硕士,研究方向:创新药制剂研发。E-mail:。

Research progress in pulmonary inhalation drug delivery system
Ni WAN , Bin CHEN, He LI, Wei-lun YE, Hui WANG
Affiliations
  • Zhuhai Livzon Microsphere Technology Co., Ltd., Zhuhai 519000, China
出版时间: 2021-08-15
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肺部给药系统具有起效快、疗效好、同时减少不良反应等优点,已成为一种倍受关注的给药方式。在全球新型给药系统药物市场中,肺部吸入给药系统占有极为重要的地位,特别是在慢性阻塞性肺病和哮喘等与呼吸道相关疾病的治疗方面具有广泛的临床应用价值。本文将从吸入制剂的最新分类、美国FDA已上市产品情况和创新性产品研究进展等方面入手,对目前最新的吸入制剂进行综述,为今后肺部吸入制剂的研发创新提供思路和启发。

肺部给药系统  /  美国FDA吸入产品  /  吸入液体制剂  /  吸入气雾剂  /  吸入粉雾剂

Pulmonary inhalation drug delivery has been becoming one of most popular therapy approaches due to its advantages of quick onset of action, improved efficacy and reduced adverse drug reaction. Pulmonary drug delivery system plays an extremely important role worldwide in the fields of developing new drug delivery systems, particularly in the treatment of respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma, which shows a promising prospect of clinical application. This review critically summarizes the latest classification of inhalable formulations, the US FDA-approved products on the market and the research progress of innovative products, aiming to provide broad ideas and new inspirations for the development of pulmonary inhalation formulations in the future.

pulmonary drug delivery system  /  inhalable products of US FDA  /  inhaled liquid preparations  /  inhaled aerosol  /  inhaled powder
万妮, 陈斌, 李合, 叶伟伦, 王慧. 肺部吸入给药系统的研究进展. 中国新药杂志, 2021 , 30 (15) : 1386 -1395 .
Ni WAN, Bin CHEN, He LI, Wei-lun YE, Hui WANG. Research progress in pulmonary inhalation drug delivery system[J]. Chinese Journal of New Drugs, 2021 , 30 (15) : 1386 -1395 .
  • 国家“重大新药创制”科技重大专项资助项目(2017ZX09201004-018)
  • 中国博士后科学基金(2019M652950)
  • 广东省“珠江人才计划”引进第六批创新创业团队(2016ZT06Y229)
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  • 首发时间:2026-10-28
  • 出版时间:2021-08-15
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  • 录用日期:2020-11-27
基金
国家“重大新药创制”科技重大专项资助项目(2017ZX09201004-018)
中国博士后科学基金(2019M652950)
广东省“珠江人才计划”引进第六批创新创业团队(2016ZT06Y229)
作者信息
    珠海市丽珠微球科技有限公司,珠海 519000

通讯作者:

王慧,女,博士生,研究方向:吸入制剂研发。联系电话:(0756)8135594,E-mail:。
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