中国新药杂志

不同结构特征的微球制剂在药物递送中的研究进展

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李乐 , 焦杰 , 周卫

中国新药杂志 | 综述 2021,30(17): 1592-1599

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中国新药杂志 |综述 2021 , 30 (17) : 1592 -1599

不同结构特征的微球制剂在药物递送中的研究进展

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李乐, 焦杰, 周卫

作者信息

中国药科大学药学院，南京　210009

通讯作者:

周卫，男，博士，研究员，研究方向：药物新剂型与新技术。E-mail：zw_why@cpu.edu.cn。

作者简介:

李乐，女，硕士研究生，研究方向：药物新剂型与新技术。E-mail：l5651647598@163.com。

Research progress of microspheres with different structural characteristics in drug delivery

Le LI, Jie JIAO, Wei ZHOU

Affiliations

School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China

出版时间: 2021-09-15

文章导航

摘要

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微球作为新型递药系统，在医药领域受到广泛关注。根据微球微观结构的不同，可将其分为实心微球、双层微球、中空微球、多孔微球。不同的微观结构赋予了微球不同的特性，使微球适用于不同的给药形式和临床用途。本文简要介绍了不同结构微球的特点、制备方法和在医药领域的应用。

关键词

微球 / 多孔微球 / 双层微球 / 中空微球

Abstract

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Microspheres, as a new delivery system, are widely concerned in the field of medicine. Microspheres can be divided into solid microspheres, double-walled microspheres, hollow microspheres and porous microspheres according to their different structures. Different microstructure endows the microspheres with different characteristics, which makes the microspheres suitable for different drug delivery forms and clinical applications. In this paper, the characteristics, preparation methods and applications of microspheres with different structures are briefly introduced.

Key words

microspheres / porous microspheres / double-walled microspheres / hollow microspheres

引用本文

李乐, 焦杰, 周卫. 不同结构特征的微球制剂在药物递送中的研究进展. 中国新药杂志, 2021 , 30 (17) : 1592 -1599 .

Le LI, Jie JIAO, Wei ZHOU. Research progress of microspheres with different structural characteristics in drug delivery[J]. Chinese Journal of New Drugs, 2021 , 30 (17) : 1592 -1599 .

参考文献

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2021年第30卷第17期

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首发时间：2026-10-28
出版时间：2021-09-15

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录用日期：2020-10-19

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中国药科大学药学院，南京　210009

通讯作者:

周卫，男，博士，研究员，研究方向：药物新剂型与新技术。E-mail：zw_why@cpu.edu.cn。

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2种不同金属材料的力学参数

科 Family	属数 Number of genus	种数 Number of species	占总种数比例 Percentage of total species (%)	属 Genus	种数 Number of species	占总种数比例 Percentage of total species (%)
鹅膏菌科Amanitaceae	2	11	5.26	鹅膏菌属 Amanita	10	4.78
小菇科 Mycenaceae	2	12	5.74	丝盖伞属 Inocybe	5	2.39
多孔菌科 Polyporaceae	8	14	6.70	蜡蘑属 Laccaria	5	2.39
红菇科 Russulaceae	3	23	11.00	小皮伞属 Marasmius	6	2.87
				小菇属 Mycena	11	5.26
				光柄菇属 Pluteus	5	2.39
				红菇属 Russula	17	8.13
				栓菌属 Trametes	5	2.39

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