Article(id=1322127435823432159, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322127420036071763, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1635696000000, acceptedDateStr=2021-11-01, onlineDate=1793149344639, onlineDateStr=2026-10-28, pubDate=1640793600000, pubDateStr=2021-12-30, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793149344639, onlineIssueDateStr=2026-10-28, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793149344639, creator=13701087609, updateTime=1793149344639, updator=13701087609, issue=Issue{id=1322127420036071763, tenantId=1146029695717560320, journalId=1235980733773295621, year='2021', volume='30', issue='24', pageStart='2225', pageEnd='2327', issueExtLink='null', onlineDate='null', pubDate='1640793600000', pubDateStr='2021-12-30', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1793149340876, creator='13701087609', updateTime=1793149575427, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322128403881374295, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322127420036071763, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322128403881374296, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322127420036071763, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=2228, endPage=2233, ext={EN=ArticleExt(id=1322127435991204320, articleId=1322127435823432159, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Analysis of current research situation of anti-tumor traditional Chinese medicine from the perspective of patents, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=

This paper analyzed the situation of patent applications of anti-tumor traditional Chinese medicine (TCM) in China in order to provide suggestions for the research, development, utilization and innovation of anti-tumor TCM. The Patentics patent database was used as the data source to search and analyze the patent application of anti-tumor TCM in China. The patent applications of anti-tumor TCM in China mainly experienced three stages: steady development (2000—2012), rapid outbreak (2013—2015) and slowing down (2016-present). However, the quality of patent applications showed an opposite trend, resulting in a low patent effective rate (21%). The quality of the patents applied by modern pharmaceutical enterprises and universities showed a higher level. The patent applications of pharmaceutical enterprises mainly focused on the extract of TCM and preparation process, while universities mainly focused on TCM composition and compound preparations. In an overall view, the patent application quality of anti-tumor TCM in China is relatively low, we should improve the patent quality, learn from the foreign patent layout experience, enhance the ability of university-enterprise collaborative innovation, and promote the inheritance and development of TCM.

, authors=Mei-tong ZANG, Jing ZHANG, Yin-li YANG, Jie ZHANG, authorsList=Mei-tong ZANG, Jing ZHANG, Yin-li YANG, Jie ZHANG, authorCompany=null, correspAuthors=Jie ZHANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322127436268028385, articleId=1322127435823432159, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=专利视角下我国抗肿瘤中药研发现状分析, columnId=1236331162679955859, journalTitle=中国新药杂志, columnName=新药述评与论坛, runingTitle=null, highlight=null, articleAbstract=

本文针对我国抗肿瘤中药的专利申请现状进行分析,旨在为抗肿瘤中药的开发利用和创新发展提供战略建议。以Patentics专利数据库为检索平台,对我国抗肿瘤中药的专利申请情况进行检索分析。我国抗肿瘤中药专利申请总量主要经历稳步发展(2000—2012年)、快速暴发(2013—2015年)和降温放缓(2016年至今)3个阶段,但专利申请质量则呈现相反的趋势,导致专利总有效率偏低(21%)。其中现代医药企业和高校院所申请人的专利质量较高,医药企业的专利申请主要围绕中药提取物及其制备工艺,高校院所的专利申请主要围绕中药组合物和复方制剂。我国抗肿瘤中药的专利申请质量偏低,申请人应注重提升抗肿瘤中药的专利质量,积极借鉴国外专利布局经验,提升校企协同创新能力,助力我国中医药传承创新发展。

, authors=臧美彤, 张静, 杨银莉, 张洁, authorsList=臧美彤, 张静, 杨银莉, 张洁, authorCompany=null, correspAuthors=张洁, authorNote=

臧美彤,女,硕士,主要从事医院药学研究。联系电话:(022)23340123,E-mail:。

, correspAuthorsNote=
张洁,女,硕士,主任药师,主要从事临床药理学及药事管理研究。联系电话:(022)23340123,E-mail:。
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臧美彤,女,硕士,主要从事医院药学研究。联系电话:(022)23340123,E-mail:。

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臧美彤,女,硕士,主要从事医院药学研究。联系电话:(022)23340123,E-mail:。

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Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2021, 71(3): 209-249., articleTitle=null, refAbstract=null), Reference(id=1322127438776222211, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322127435823432159, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[2], rfOrder=1, authorNames=null, journalName=null, refType=null, unstructuredReference=BRAY F, LAVERSANNE M, WEIDERPASS E, et al. The ever-increasing importance of cancer as a leading cause of premature death worldwide[J]. Cancer, 2021, 127(16): 3029-3030., articleTitle=null, refAbstract=null), Reference(id=1322127438860108292, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322127435823432159, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[3], rfOrder=2, authorNames=null, journalName=null, refType=null, unstructuredReference=XIANG YN, GUO ZM, ZHU PF, et al. Traditional Chinese medicine as a cancer treatment: modern perspectives of ancient but advanced science[J]. Cancer Med, 2019, 8(5): 1958-1975., articleTitle=null, refAbstract=null), Reference(id=1322127439002714629, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322127435823432159, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[4], rfOrder=3, authorNames=null, journalName=null, refType=null, unstructuredReference=梁凯桐, 魏裕涛, 刘子志. 我国中药治疗高死亡率疾病的发明专利分布研究——基于国际专利分类号A61P的分析机制[J]. 中草药, 2020, 51(17): 4598-4604., articleTitle=null, refAbstract=null), Reference(id=1322127439141126662, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322127435823432159, doi=null, pmid=null, pmcid=null, year=null, volume=null, issue=null, pageStart=null, pageEnd=null, url=null, language=null, rfNumber=[5], rfOrder=4, authorNames=null, journalName=null, refType=null, unstructuredReference=杨琳琳, 王青, 段洁. 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专利视角下我国抗肿瘤中药研发现状分析
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臧美彤 , 张静 , 杨银莉 , 张洁
中国新药杂志 | 新药述评与论坛 2021,30(24): 2228-2233
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中国新药杂志 |新药述评与论坛 2021 , 30 (24) : 2228 -2233
专利视角下我国抗肿瘤中药研发现状分析
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臧美彤,女,硕士,主要从事医院药学研究。联系电话:(022)23340123,E-mail:。

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臧美彤 , 张静, 杨银莉, 张洁
作者信息
  • 天津医科大学肿瘤医院,国家肿瘤临床医学研究中心,天津市肿瘤防治重点实验室,天津市恶性肿瘤临床医学研究中心,天津 300060
通讯作者:
张洁,女,硕士,主任药师,主要从事临床药理学及药事管理研究。联系电话:(022)23340123,E-mail:。
作者简介:

臧美彤,女,硕士,主要从事医院药学研究。联系电话:(022)23340123,E-mail:。

Analysis of current research situation of anti-tumor traditional Chinese medicine from the perspective of patents
Mei-tong ZANG , Jing ZHANG, Yin-li YANG, Jie ZHANG
Affiliations
  • Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Clinical Research Center for Cancer, Tianjin 300060, China
出版时间: 2021-12-30
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本文针对我国抗肿瘤中药的专利申请现状进行分析,旨在为抗肿瘤中药的开发利用和创新发展提供战略建议。以Patentics专利数据库为检索平台,对我国抗肿瘤中药的专利申请情况进行检索分析。我国抗肿瘤中药专利申请总量主要经历稳步发展(2000—2012年)、快速暴发(2013—2015年)和降温放缓(2016年至今)3个阶段,但专利申请质量则呈现相反的趋势,导致专利总有效率偏低(21%)。其中现代医药企业和高校院所申请人的专利质量较高,医药企业的专利申请主要围绕中药提取物及其制备工艺,高校院所的专利申请主要围绕中药组合物和复方制剂。我国抗肿瘤中药的专利申请质量偏低,申请人应注重提升抗肿瘤中药的专利质量,积极借鉴国外专利布局经验,提升校企协同创新能力,助力我国中医药传承创新发展。

专利分析  /  抗肿瘤  /  中药  /  研发现状

This paper analyzed the situation of patent applications of anti-tumor traditional Chinese medicine (TCM) in China in order to provide suggestions for the research, development, utilization and innovation of anti-tumor TCM. The Patentics patent database was used as the data source to search and analyze the patent application of anti-tumor TCM in China. The patent applications of anti-tumor TCM in China mainly experienced three stages: steady development (2000—2012), rapid outbreak (2013—2015) and slowing down (2016-present). However, the quality of patent applications showed an opposite trend, resulting in a low patent effective rate (21%). The quality of the patents applied by modern pharmaceutical enterprises and universities showed a higher level. The patent applications of pharmaceutical enterprises mainly focused on the extract of TCM and preparation process, while universities mainly focused on TCM composition and compound preparations. In an overall view, the patent application quality of anti-tumor TCM in China is relatively low, we should improve the patent quality, learn from the foreign patent layout experience, enhance the ability of university-enterprise collaborative innovation, and promote the inheritance and development of TCM.

patent analysis  /  anti-tumor drug  /  traditional Chinese medicine  /  current situation of research and development
臧美彤, 张静, 杨银莉, 张洁. 专利视角下我国抗肿瘤中药研发现状分析. 中国新药杂志, 2021 , 30 (24) : 2228 -2233 .
Mei-tong ZANG, Jing ZHANG, Yin-li YANG, Jie ZHANG. Analysis of current research situation of anti-tumor traditional Chinese medicine from the perspective of patents[J]. Chinese Journal of New Drugs, 2021 , 30 (24) : 2228 -2233 .
  • 国家自然科学基金青年基金资助项目(81703786)
参考文献 引证文献
排序方式:
[1]
SUNG H, FERLAY J, SIEGEL RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2021, 71(3): 209-249.
[2]
BRAY F, LAVERSANNE M, WEIDERPASS E, et al. The ever-increasing importance of cancer as a leading cause of premature death worldwide[J]. Cancer, 2021, 127(16): 3029-3030.
[3]
XIANG YN, GUO ZM, ZHU PF, et al. Traditional Chinese medicine as a cancer treatment: modern perspectives of ancient but advanced science[J]. Cancer Med, 2019, 8(5): 1958-1975.
[4]
梁凯桐, 魏裕涛, 刘子志. 我国中药治疗高死亡率疾病的发明专利分布研究——基于国际专利分类号A61P的分析机制[J]. 中草药, 2020, 51(17): 4598-4604.
[5]
杨琳琳, 王青, 段洁. Patentics和incoPat两种专利检索系统的体验之对比[J]. 专利代理, 2019(2): 88-92.
[6]
王彦峰, 扆铁梅, 刘海波. 黄芩专利格局分析[J]. 中草药, 2019, 50(20): 5117-5124.
[7]
郭青, 戚湧, 高盼军. 基于技术、法律和经济三位一体的专利质量评价及应用研究[J]. 中国发明与专利, 2021, 18(1): 21-29.
[8]
郭德海, 束云, 王冰, 等. 非小细胞肺癌相关国内外中药发明专利分析[J]. 世界中医药, 2019, 14(12): 3400-3405.
[9]
陈创荣, 冯毅翀, 陈旭红, 等. 抗肿瘤中药专利申请分析及其建议[J]. 中医肿瘤学杂志, 2021, 3(1): 12, 21-24.
[10]
曾莉, 蒋文蹊. 江苏中药发明专利申请质量研究[J]. 科技与经济, 2020, 33(1): 41-45.
[11]
郭越, 汤少梁. 专利保护视角下我国中药保护现状与对策探讨[J]. 中国卫生事业管理, 2016, 33(7): 520-523.
[12]
辛雪, 黄大智. 从专利分析角度比较中国和日本经典方剂的新药研究[J]. 中国新药杂志, 2020, 29(5): 487-493.
[13]
LIN YC, HUANG WT, OU SC, et al. Neural network analysis of Chinese herbal medicine prescriptions for patients with colorectal cancer[J]. Compl Ther Med, 2019, 42(12): 279-285.
2021年第30卷第24期
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  • 首发时间:2026-10-28
  • 出版时间:2021-12-30
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  • 录用日期:2021-11-01
基金
国家自然科学基金青年基金资助项目(81703786)
作者信息
    天津医科大学肿瘤医院,国家肿瘤临床医学研究中心,天津市肿瘤防治重点实验室,天津市恶性肿瘤临床医学研究中心,天津 300060

通讯作者:

张洁,女,硕士,主任药师,主要从事临床药理学及药事管理研究。联系电话:(022)23340123,E-mail:。
参考文献
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2种不同金属材料的力学参数
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Percentage of
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属
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Number of
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Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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