Article(id=1322125581865562353, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322125552731927464, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1628265600000, acceptedDateStr=2021-08-07, onlineDate=1793148902621, onlineDateStr=2026-10-28, pubDate=1638201600000, pubDateStr=2021-11-30, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793148902621, onlineIssueDateStr=2026-10-28, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793148902621, creator=13701087609, updateTime=1793148902621, updator=13701087609, issue=Issue{id=1322125552731927464, tenantId=1146029695717560320, journalId=1235980733773295621, year='2021', volume='30', issue='22', pageStart='2017', pageEnd='2120', issueExtLink='null', onlineDate='null', pubDate='1638201600000', pubDateStr='2021-11-30', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1793148895675, creator='13701087609', updateTime=1793149501548, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322128094022971944, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322125552731927464, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322128094022971945, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1322125552731927464, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=2111, endPage=2115, ext={EN=ArticleExt(id=1322125582062694642, articleId=1322125581865562353, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Evaluation of the performance of one kind of imported nitrofurantoin susceptibility test disk, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To evaluate the detection performance of one kind of imported nitrofurantoin susceptibility test disk for antimicrobial susceptibility test by disk diffusion method.
Methods: A total of 118 strains of pathogenic bacteria were collected from a Class A tertiary comprehensive hospital in Beijing from 2016 to 2017, including 61 isolates of Enterobacterales, 48 isolates of Staphylococcus spp. and 9 isolates of Enterococcus spp. Antimicrobial susceptibility test was performed following Clinical and Laboratory Standards Institute (CLSI) documents M100ED30, using disk diffusion method. The differences of susceptibility between domestic disks and imported disks against 118 bacteria strains were detected according to the breakpoints described in CLSI documents M100ED30. The rate of categorical agreement (CA) of susceptibility conducted by the two kinds of disks was calculated.
Results: Among the 118 isolates, 73, 4 and 41 were categorized as susceptible (S), intermediate (I), and resistant (R) to nitrofurantoin, respectively. The rate of categorical agreement of susceptibility to nitrofurantoin using imported disks and domestic disks was 100%.
Conclusion: The results of susceptibility test using imported nitrofurantoin disks are reliable, and consistent with the results by domestic nitrofurantoin disks. Imported nitrofurantoin disk can meet the requirements of clinical laboratory. The test results will provide direct reference data for clinical application for nitrofurantoin in infectious diseases.
, authors=Ge ZHANG
1, 2, Jing-jing HUANG
1, 2, 3, Si-meng DUAN
1, 2, Jing-jia ZHANG
1, 2, Ying ZHAO
1, 2, Chun-ying XU
1, 2, authorsList=Ge ZHANG, Jing-jing HUANG, Si-meng DUAN, Jing-jia ZHANG, Ying ZHAO, Chun-ying XU, authorCompany=null, correspAuthors=Ying ZHAO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322125582679257331, articleId=1322125581865562353, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=一种进口呋喃妥因药敏纸片试验性能评价, columnId=1236330556003242277, journalTitle=中国新药杂志, columnName=实验研究, runingTitle=null, highlight=null, articleAbstract=
目的： 评估一种进口呋喃妥因药敏纸片产品的检测性能。
方法： 收集北京地区一家三甲医院2016—2017年从临床标本中分离的118株病原菌，包括肠杆菌目细菌61株、葡萄球菌属48株、肠球菌属9株。依照美国临床和实验室标准协会（Clinical and Laboratory Standards Institute，CLSI）文件M100ED30，对国产和进口呋喃妥因药敏纸片采用纸片扩散法进行体外药物敏感性试验检测，并根据其临床折点进行结果判读，比较2种纸片判读结果的分类一致率（CA）。
结果： 118株病原菌中，有73株对呋喃妥因敏感，4株中介，41株耐药。进口与国产体外药敏实验纸片的分类一致率为100%。
结论： 该呋喃妥因进口药敏实验纸片体外抗菌药物敏感性试验结果可靠，与国产体外药敏实验纸片一致性好，可以满足实验室需求，为临床感染性疾病诊疗提供用药参考。
, authors=张戈
1, 2, 黄晶晶
1, 2, 3, 段思蒙
1, 2, 张京家
1, 2, 赵颖
1, 2, 徐春英
1, 2, authorsList=张戈, 黄晶晶, 段思蒙, 张京家, 赵颖, 徐春英, authorCompany=null, correspAuthors=赵颖, authorNote=
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, copyrightStatement=null, copyrightOwner=《中国新药杂志》有限公司, extLink=null, articleAbsUrl=null, sourceXml=dd/7GKvi17pznK3mmXrSQg==, magXml=jrKQSoQuKn+UKNd21r4kXw==, pdfUrl=null, pdf=zWNCRQiCd3LIuQvS8sfW+Q==, pdfFileSize=834063, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=3U37ipVWw41bUrIEMryHSA==, mapNumber=null, fund=null)}, authors=[Author(id=1322125583333568766, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322125581865562353, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=zhangeshero@163.com, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1322125583451009281, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322125581865562353, authorId=1322125583333568766, language=EN, stringName=Ge ZHANG, firstName=Ge, middleName=null, lastName=ZHANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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1Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
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1中国医学科学院北京协和医院检验科，北京 100730
2侵袭性真菌病机制研究与精准诊断北京市重点实验室，北京 100730, bio={"content":"
张戈，女，初级检验师，主要从事临床医学检验和病原微生物流行病学研究。联系电话：（010）69159747，E-mail：zhangeshero@163.com。
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张戈，女，初级检验师，主要从事临床医学检验和病原微生物流行病学研究。联系电话：（010）69159747，E-mail：zhangeshero@163.com。
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1, 2, 3, address=
1Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
2Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Beijing 100730, China
3Graduate School, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100730, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322125583836885257, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322125581865562353, authorId=1322125583656530180, language=CN, stringName=黄晶晶, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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1中国医学科学院北京协和医院检验科，北京 100730
2侵袭性真菌病机制研究与精准诊断北京市重点实验室，北京 100730
3中国医学科学院北京协和医学院研究生院，北京 100730, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322125582947692788, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322125581865562353, xref=1, ext=[AuthorCompanyExt(id=1322125582993830133, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322125581865562353, companyId=1322125582947692788, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China), AuthorCompanyExt(id=1322125583010607350, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322125581865562353, companyId=1322125582947692788, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
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1, 2, address=
1Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
2Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Beijing 100730, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322125584109515023, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322125581865562353, authorId=1322125583912382731, language=CN, stringName=段思蒙, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, address=
1中国医学科学院北京协和医院检验科，北京 100730
2侵袭性真菌病机制研究与精准诊断北京市重点实验室，北京 100730, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322125582947692788, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322125581865562353, xref=1, ext=[AuthorCompanyExt(id=1322125582993830133, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322125581865562353, companyId=1322125582947692788, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
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1, 2, address=
1Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
2Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Beijing 100730, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1322125584382144789, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322125581865562353, authorId=1322125584185012497, language=CN, stringName=张京家, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 2, address=
1中国医学科学院北京协和医院检验科，北京 100730
2侵袭性真菌病机制研究与精准诊断北京市重点实验室，北京 100730, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1322125582947692788, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322125581865562353, xref=1, ext=[AuthorCompanyExt(id=1322125582993830133, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1322125581865562353, companyId=1322125582947692788, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
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