Article(id=1321425830635483492, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425776323449136, articleNumber=null, orderNo=null, doi=10.20251/j.cnki.1003-3734.2026.14.010, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1758470400000, acceptedDateStr=2025-09-22, onlineDate=1792982068928, onlineDateStr=2026-10-26, pubDate=1785340800000, pubDateStr=2026-07-30, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792982068928, onlineIssueDateStr=2026-10-26, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792982068928, creator=13701087609, updateTime=1792982068928, updator=13701087609, issue=Issue{id=1321425776323449136, tenantId=1146029695717560320, journalId=1235980733773295621, year='2026', volume='35', issue='14', pageStart='1457', pageEnd='1568', issueExtLink='null', onlineDate='null', pubDate='1785340800000', pubDateStr='2026-07-30', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792982055979, creator='13701087609', updateTime=1792982930455, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1321429444191966074, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425776323449136, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1321429444196160379, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425776323449136, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1516, endPage=1526, ext={EN=ArticleExt(id=1321425830820032869, articleId=1321425830635483492, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Historical evolution of malt processing, modern research progress and prediction and analysis of quality markers, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Malt is a dried product of barley germination, which is widely used in the fields of traditional Chinese medicine and food industry. By combing ancient books and literature, the historical evolution and modern research progress in malt processing methods were summarized. The quality markers of malt were analyzed and predicted by system pharmacology, and finally luteolin, tricin, delphinidin and 5,7-dihydroxy-3′, 4′, 5′-trimethoxyflavon were screened as the quality markers of malt. This study provided theoretical basis and research ideas for the in-depth study of different processed varieties of malt and the establishment of quality standards.

, authors=Yin SU1, Xin WANG1, Ling-yun ZHONG1, Tu-lin LU2, Jin-xiang ZENG1, Jing ZHU1, *, authorsList=Yin SU, Xin WANG, Ling-yun ZHONG, Tu-lin LU, Jin-xiang ZENG, Jing ZHU, authorCompany=null, correspAuthors=Jing ZHU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1321425831210103142, articleId=1321425830635483492, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=麦芽炮制历史沿革、现代研究进展及质量标志物预测分析, columnId=1236330553964810454, journalTitle=中国新药杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

麦芽为大麦发芽干燥制品,具有消食健脾等功效,在中医药及食品工业领域应用广泛。本文通过梳理古籍及文献,对麦芽炮制方法历史沿革与现代研究进展进行归纳总结,应用系统药理学对麦芽的质量标志物(quality marker, Q-marker)进行分析预测,筛选出木犀草素、麦黄酮、飞燕草素、5,7-二羟基-3′,4′,5′-三甲氧基黄酮可作为麦芽的Q-marker,以期为麦芽不同炮制品种的深入研究与质量标准建立提供理论依据和研究思路。

, authors=苏印1, 王鑫1, 钟凌云1, 陆兔林2, 曾金祥1, 祝婧1, *, authorsList=苏印, 王鑫, 钟凌云, 陆兔林, 曾金祥, 祝婧, authorCompany=null, correspAuthors=祝婧, authorNote=

苏印,女,硕士研究生,研究方向:中药炮制学。E-mail: 。

, correspAuthorsNote=
* 祝婧,女,教授,博士生导师,研究方向:中药、民族药饮片质量标准及炮制机制研究。E-mail: 。
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苏印,女,硕士研究生,研究方向:中药炮制学。E-mail: 。

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苏印,女,硕士研究生,研究方向:中药炮制学。E-mail: 。

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麦芽炮制历史沿革、现代研究进展及质量标志物预测分析
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苏印 1 , 王鑫 1 , 钟凌云 1 , 陆兔林 2 , 曾金祥 1 , 祝婧 1, *
中国新药杂志 | 综述 2026,35(14): 1516-1526
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中国新药杂志 |综述 2026 , 35 (14) : 1516 -1526
麦芽炮制历史沿革、现代研究进展及质量标志物预测分析
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苏印1 , 王鑫1, 钟凌云1, 陆兔林2, 曾金祥1, 祝婧1, *
作者信息
  • 1江西中医药大学,南昌 330004
  • 2南京中医药大学,南京 210023
通讯作者:
* 祝婧,女,教授,博士生导师,研究方向:中药、民族药饮片质量标准及炮制机制研究。E-mail: 。
作者简介:

苏印,女,硕士研究生,研究方向:中药炮制学。E-mail: 。

Historical evolution of malt processing, modern research progress and prediction and analysis of quality markers
Yin SU1 , Xin WANG1, Ling-yun ZHONG1, Tu-lin LU2, Jin-xiang ZENG1, Jing ZHU1, *
Affiliations
  • 1Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China
  • 2Nanjing University of Traditional Chinese Medicine, Nanjing 210023, China
出版时间: 2026-07-30 doi: 10.20251/j.cnki.1003-3734.2026.14.010
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麦芽为大麦发芽干燥制品,具有消食健脾等功效,在中医药及食品工业领域应用广泛。本文通过梳理古籍及文献,对麦芽炮制方法历史沿革与现代研究进展进行归纳总结,应用系统药理学对麦芽的质量标志物(quality marker, Q-marker)进行分析预测,筛选出木犀草素、麦黄酮、飞燕草素、5,7-二羟基-3′,4′,5′-三甲氧基黄酮可作为麦芽的Q-marker,以期为麦芽不同炮制品种的深入研究与质量标准建立提供理论依据和研究思路。

麦芽  /  炮制  /  历史沿革  /  化学成分  /  药理作用  /  质量标志物

Malt is a dried product of barley germination, which is widely used in the fields of traditional Chinese medicine and food industry. By combing ancient books and literature, the historical evolution and modern research progress in malt processing methods were summarized. The quality markers of malt were analyzed and predicted by system pharmacology, and finally luteolin, tricin, delphinidin and 5,7-dihydroxy-3′, 4′, 5′-trimethoxyflavon were screened as the quality markers of malt. This study provided theoretical basis and research ideas for the in-depth study of different processed varieties of malt and the establishment of quality standards.

malt  /  processing  /  historical evolution  /  chemical constituents  /  pharmacological effects  /  quality markers
苏印, 王鑫, 钟凌云, 陆兔林, 曾金祥, 祝婧. 麦芽炮制历史沿革、现代研究进展及质量标志物预测分析. 中国新药杂志, 2026 , 35 (14) : 1516 -1526 . DOI: 10.20251/j.cnki.1003-3734.2026.14.010
Yin SU, Xin WANG, Ling-yun ZHONG, Tu-lin LU, Jin-xiang ZENG, Jing ZHU. Historical evolution of malt processing, modern research progress and prediction and analysis of quality markers[J]. Chinese Journal of New Drugs, 2026 , 35 (14) : 1516 -1526 . DOI: 10.20251/j.cnki.1003-3734.2026.14.010
  • 国家重点研发计划资助项目(2023YFC3504200)
  • 江西省重点研发计划-产业链科技创新联合体揭榜挂帅项目(20224BBG71022)
  • 中药炮制传承创新与转化江西省重点实验室资助项目(2024SSY07091)
  • 江西中医药大学大学生创新创业训练计划资助项目(202410412188)
  • 江西中医药大学中药炮制技术传承创新团队资助项目(CXTD22003)
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2026年第35卷第14期
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doi: 10.20251/j.cnki.1003-3734.2026.14.010
  • 首发时间:2026-10-26
  • 出版时间:2026-07-30
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  • 录用日期:2025-09-22
基金
国家重点研发计划资助项目(2023YFC3504200)
江西省重点研发计划-产业链科技创新联合体揭榜挂帅项目(20224BBG71022)
中药炮制传承创新与转化江西省重点实验室资助项目(2024SSY07091)
江西中医药大学大学生创新创业训练计划资助项目(202410412188)
江西中医药大学中药炮制技术传承创新团队资助项目(CXTD22003)
作者信息
    1江西中医药大学,南昌 330004
    2南京中医药大学,南京 210023

通讯作者:

* 祝婧,女,教授,博士生导师,研究方向:中药、民族药饮片质量标准及炮制机制研究。E-mail: 。
参考文献
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https://castjournals.cast.org.cn/joweb/zgxyzz/CN/10.20251/j.cnki.1003-3734.2026.14.010
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2种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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