Article(id=1321425827489763835, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425812331549069, articleNumber=null, orderNo=null, doi=10.20251/j.cnki.1003-3734.2026.15.008, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1766678400000, acceptedDateStr=2025-12-26, onlineDate=1792982068178, onlineDateStr=2026-10-26, pubDate=1786723200000, pubDateStr=2026-08-15, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792982068178, onlineIssueDateStr=2026-10-26, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792982068178, creator=13701087609, updateTime=1792982068178, updator=13701087609, issue=Issue{id=1321425812331549069, tenantId=1146029695717560320, journalId=1235980733773295621, year='2026', volume='35', issue='15', pageStart='1569', pageEnd='1680', issueExtLink='null', onlineDate='null', pubDate='1786723200000', pubDateStr='2026-08-15', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792982064564, creator='13701087609', updateTime=1792982904202, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1321429334083097400, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425812331549069, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1321429334087291705, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425812331549069, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1627, endPage=1633, ext={EN=ArticleExt(id=1321425827816919548, articleId=1321425827489763835, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Research progress on yttrium-90 transarterial radioembolization for hepatocellular carcinoma, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Hepatocellular carcinoma (HCC) is characterized by its insidious onset, difficulty in early diagnosis, rapid disease progression, and poor prognosis, making it a major global health threat. Yttrium-90 transarterial radioembolization (TARE) is an emerging local treatment for liver cancer. Although its clinical application in mainland China is relatively recent, studies have shown promising clinical prospects. This article reviews the efficacy and safety of TARE in the treatment of HCC patients by reviewing literature, aiming to provide reference for clinical medication.

, authors=Bei-bei HAN1, Meng-da CAO2, Feng YU1, *, Hua SHAO2, *, authorsList=Bei-bei HAN, Meng-da CAO, Feng YU, Hua SHAO, authorCompany=null, correspAuthors=Feng YU, Hua SHAO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1321425828135686653, articleId=1321425827489763835, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=钇90经动脉放射栓塞治疗肝细胞癌研究进展, columnId=1236330553964810454, journalTitle=中国新药杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

肝细胞癌(hepatocellular carcinoma, HCC)发病隐匿,早期诊断困难,并且疾病进展快,预后差,已成为全球性的重大健康威胁。钇90经动脉放射栓塞(transarterial radioembolization, TARE)是一种新兴的肝癌局部治疗方式,尽管在我国大陆临床应用时间尚短,但已有研究表明其临床应用前景良好。本文通过查阅文献资料,对TARE治疗HCC患者的有效性、安全性进行综述,以期为临床用药提供参考。

, authors=韩蓓蓓1, 曹梦妲2, 于锋1, *, 邵华2, *, authorsList=韩蓓蓓, 曹梦妲, 于锋, 邵华, authorCompany=null, correspAuthors=于锋, 邵华, authorNote=

曹梦妲,女,博士,副研究员,研究方向:临床药学,E-mail: 。

韩蓓蓓,女,硕士研究生,研究方向:临床药学。E-mail: 。

, correspAuthorsNote=
* 邵华,女,博士,主任药师,研究方向:临床药学、药事管理。联系电话:(025)83262632,E-mail: 。
* 于锋,男,博士,教授,研究方向:药理学、临床药学。E-mail: 。
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韩蓓蓓,女,硕士研究生,研究方向:临床药学。E-mail: 。

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韩蓓蓓,女,硕士研究生,研究方向:临床药学。E-mail: 。

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钇90经动脉放射栓塞治疗肝细胞癌研究进展
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韩蓓蓓 1 , 曹梦妲 2 , 于锋 1, * , 邵华 2, *
中国新药杂志 | 综述 2026,35(15): 1627-1633
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中国新药杂志 |综述 2026 , 35 (15) : 1627 -1633
钇90经动脉放射栓塞治疗肝细胞癌研究进展
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韩蓓蓓1 , 曹梦妲2 , 于锋1, * , 邵华2, *
作者信息
  • 1中国药科大学基础医学与临床药学学院,南京 210009
  • 2东南大学附属中大医院药学部,南京 210009
通讯作者:
* 邵华,女,博士,主任药师,研究方向:临床药学、药事管理。联系电话:(025)83262632,E-mail: 。
* 于锋,男,博士,教授,研究方向:药理学、临床药学。E-mail: 。
作者简介:

曹梦妲,女,博士,副研究员,研究方向:临床药学,E-mail: 。

韩蓓蓓,女,硕士研究生,研究方向:临床药学。E-mail: 。

Research progress on yttrium-90 transarterial radioembolization for hepatocellular carcinoma
Bei-bei HAN1 , Meng-da CAO2 , Feng YU1, * , Hua SHAO2, *
Affiliations
  • 1School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, Nanjing 210009, China
  • 2Department of Pharmacy, Zhongda Hospital, Southeast University, Nanjing 210009, China
出版时间: 2026-08-15 doi: 10.20251/j.cnki.1003-3734.2026.15.008
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肝细胞癌(hepatocellular carcinoma, HCC)发病隐匿,早期诊断困难,并且疾病进展快,预后差,已成为全球性的重大健康威胁。钇90经动脉放射栓塞(transarterial radioembolization, TARE)是一种新兴的肝癌局部治疗方式,尽管在我国大陆临床应用时间尚短,但已有研究表明其临床应用前景良好。本文通过查阅文献资料,对TARE治疗HCC患者的有效性、安全性进行综述,以期为临床用药提供参考。

肝细胞癌  /  钇90  /  选择性内放射治疗  /  经动脉放射栓塞  /  介入治疗

Hepatocellular carcinoma (HCC) is characterized by its insidious onset, difficulty in early diagnosis, rapid disease progression, and poor prognosis, making it a major global health threat. Yttrium-90 transarterial radioembolization (TARE) is an emerging local treatment for liver cancer. Although its clinical application in mainland China is relatively recent, studies have shown promising clinical prospects. This article reviews the efficacy and safety of TARE in the treatment of HCC patients by reviewing literature, aiming to provide reference for clinical medication.

hepatocellular carcinoma  /  yttrium 90  /  selective internal radiation therapy  /  transarterial radioembolization  /  interventional therapy
韩蓓蓓, 曹梦妲, 于锋, 邵华. 钇90经动脉放射栓塞治疗肝细胞癌研究进展. 中国新药杂志, 2026 , 35 (15) : 1627 -1633 . DOI: 10.20251/j.cnki.1003-3734.2026.15.008
Bei-bei HAN, Meng-da CAO, Feng YU, Hua SHAO. Research progress on yttrium-90 transarterial radioembolization for hepatocellular carcinoma[J]. Chinese Journal of New Drugs, 2026 , 35 (15) : 1627 -1633 . DOI: 10.20251/j.cnki.1003-3734.2026.15.008
  • 白求恩耀动神州-药学科研能力建设基金资助项目(Z04JKM2023E040)
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doi: 10.20251/j.cnki.1003-3734.2026.15.008
  • 首发时间:2026-10-26
  • 出版时间:2026-08-15
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  • 录用日期:2025-12-26
基金
白求恩耀动神州-药学科研能力建设基金资助项目(Z04JKM2023E040)
作者信息
    1中国药科大学基础医学与临床药学学院,南京 210009
    2东南大学附属中大医院药学部,南京 210009

通讯作者:

* 邵华,女,博士,主任药师,研究方向:临床药学、药事管理。联系电话:(025)83262632,E-mail: 。
* 于锋,男,博士,教授,研究方向:药理学、临床药学。E-mail: 。
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https://castjournals.cast.org.cn/joweb/zgxyzz/CN/10.20251/j.cnki.1003-3734.2026.15.008
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2种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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