Article(id=1321425783785116016, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425776323449136, articleNumber=null, orderNo=null, doi=10.20251/j.cnki.1003-3734.2026.14.009, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1753113600000, acceptedDateStr=2025-07-22, onlineDate=1792982057758, onlineDateStr=2026-10-26, pubDate=1785340800000, pubDateStr=2026-07-30, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792982057758, onlineIssueDateStr=2026-10-26, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792982057758, creator=13701087609, updateTime=1792982057758, updator=13701087609, issue=Issue{id=1321425776323449136, tenantId=1146029695717560320, journalId=1235980733773295621, year='2026', volume='35', issue='14', pageStart='1457', pageEnd='1568', issueExtLink='null', onlineDate='null', pubDate='1785340800000', pubDateStr='2026-07-30', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792982055979, creator='13701087609', updateTime=1792982930455, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1321429444191966074, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425776323449136, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1321429444196160379, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425776323449136, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1510, endPage=1515, ext={EN=ArticleExt(id=1321425785441866097, articleId=1321425783785116016, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=An introduction to tablet in tablet technology and discussion on pharmaceutical research, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Tablet in tablet technology, as a new type of drug formulation technology, uses a specific pressing process to wrap the active ingredient or drug containing layer in the middle, and the outer layer is covered with one or more coating layers with different functions such as protection, sustained and controlled release, isolation, etc.. Tablet in tablet technology endows drugs with unique drug release and functional characteristics through special preparation processes and structural design, thereby achieving precise regulation of drug release, enhancing drug stability, and improving other drug properties. In recent years, it has received widespread attention. This article summarizes the development history, principles, and characteristics of tablet in tablet technology through relevant literature research. It also elaborates on the innovative applications of tablet in tablet technology and explores pharmaceutical research, in order to provide some references for the research and development of such formulations.

, authors=Jing PAN, Xiao-long HUANG*, authorsList=Jing PAN, Xiao-long HUANG, authorCompany=null, correspAuthors=Xiao-long HUANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1321425785764827506, articleId=1321425783785116016, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=包芯片制备技术介绍及药学研究探讨, columnId=1236330553964810454, journalTitle=中国新药杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

包芯片制备技术作为一种新型的药物制剂技术,运用特定的压制工艺,将药物活性成分或含药层包裹于中间,外层覆盖一层或多层具备不同功能(如保护、缓释/控释、隔离等)包衣层的药物制剂形式。包芯片通过特殊的制备工艺与结构设计,赋予药物独特的释药特性与功能特性,从而实现对药物释放的精准调控,提升药物的稳定性,并改善药物的其他性能,近年来受到广泛关注。本文通过相关文献调研,概述包芯片制备技术发展历程、制备技术原理、制备技术特点,结合包芯片制备技术的创新应用进行阐述,并对药学研究进行探讨,以期为该类制剂研究开发提供一定参考。

, authors=潘静, 黄晓龙*, authorsList=潘静, 黄晓龙, authorCompany=null, correspAuthors=黄晓龙, authorNote=

潘静,女,硕士,主要从事药品审评相关工作。联系电话:(0755)36696249,E-mail: 。

, correspAuthorsNote=
* 黄晓龙,男,硕士,主要从事药品审评相关工作。联系电话:(0755)33249888,E-mail: 。
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潘静,女,硕士,主要从事药品审评相关工作。联系电话:(0755)36696249,E-mail: 。

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潘静,女,硕士,主要从事药品审评相关工作。联系电话:(0755)36696249,E-mail: 。

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包芯片制备技术介绍及药学研究探讨
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潘静 , 黄晓龙 *
中国新药杂志 | 综述 2026,35(14): 1510-1515
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包芯片制备技术介绍及药学研究探讨
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潘静 , 黄晓龙*
作者信息
  • 国家药品监督管理局药品审评检查大湾区分中心,深圳 518017
通讯作者:
* 黄晓龙,男,硕士,主要从事药品审评相关工作。联系电话:(0755)33249888,E-mail: 。
作者简介:

潘静,女,硕士,主要从事药品审评相关工作。联系电话:(0755)36696249,E-mail: 。

An introduction to tablet in tablet technology and discussion on pharmaceutical research
Jing PAN , Xiao-long HUANG*
Affiliations
  • Greater Bay Area Center for Drug Evaluation and Inspection of National Medical Products Administration, Shenzhen 518017, China
出版时间: 2026-07-30 doi: 10.20251/j.cnki.1003-3734.2026.14.009
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包芯片制备技术作为一种新型的药物制剂技术,运用特定的压制工艺,将药物活性成分或含药层包裹于中间,外层覆盖一层或多层具备不同功能(如保护、缓释/控释、隔离等)包衣层的药物制剂形式。包芯片通过特殊的制备工艺与结构设计,赋予药物独特的释药特性与功能特性,从而实现对药物释放的精准调控,提升药物的稳定性,并改善药物的其他性能,近年来受到广泛关注。本文通过相关文献调研,概述包芯片制备技术发展历程、制备技术原理、制备技术特点,结合包芯片制备技术的创新应用进行阐述,并对药学研究进行探讨,以期为该类制剂研究开发提供一定参考。

包芯片技术  /  压制包芯片  /  一步干法包芯片  /  制备技术  /  药学研究

Tablet in tablet technology, as a new type of drug formulation technology, uses a specific pressing process to wrap the active ingredient or drug containing layer in the middle, and the outer layer is covered with one or more coating layers with different functions such as protection, sustained and controlled release, isolation, etc.. Tablet in tablet technology endows drugs with unique drug release and functional characteristics through special preparation processes and structural design, thereby achieving precise regulation of drug release, enhancing drug stability, and improving other drug properties. In recent years, it has received widespread attention. This article summarizes the development history, principles, and characteristics of tablet in tablet technology through relevant literature research. It also elaborates on the innovative applications of tablet in tablet technology and explores pharmaceutical research, in order to provide some references for the research and development of such formulations.

tablet in tablet technology  /  compression-coated tablets  /  one-step dry-coated tablets  /  preparation technology  /  pharmaceutical research
潘静, 黄晓龙. 包芯片制备技术介绍及药学研究探讨. 中国新药杂志, 2026 , 35 (14) : 1510 -1515 . DOI: 10.20251/j.cnki.1003-3734.2026.14.009
Jing PAN, Xiao-long HUANG. An introduction to tablet in tablet technology and discussion on pharmaceutical research[J]. Chinese Journal of New Drugs, 2026 , 35 (14) : 1510 -1515 . DOI: 10.20251/j.cnki.1003-3734.2026.14.009

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doi: 10.20251/j.cnki.1003-3734.2026.14.009
  • 首发时间:2026-10-26
  • 出版时间:2026-07-30
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  • 录用日期:2025-07-22
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    国家药品监督管理局药品审评检查大湾区分中心,深圳 518017

通讯作者:

* 黄晓龙,男,硕士,主要从事药品审评相关工作。联系电话:(0755)33249888,E-mail: 。
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2种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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