Article(id=1321425711697605037, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425656810951355, articleNumber=null, orderNo=null, doi=10.20251/j.cnki.1003-3734.2026.10.005, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1763308800000, acceptedDateStr=2025-11-17, onlineDate=1792982040570, onlineDateStr=2026-10-26, pubDate=1780070400000, pubDateStr=2026-05-30, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792982040570, onlineIssueDateStr=2026-10-26, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792982040570, creator=13701087609, updateTime=1792982040570, updator=13701087609, issue=Issue{id=1321425656810951355, tenantId=1146029695717560320, journalId=1235980733773295621, year='2026', volume='35', issue='10', pageStart='1009', pageEnd='1120', issueExtLink='null', onlineDate='null', pubDate='1780070400000', pubDateStr='2026-05-30', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792982027485, creator='13701087609', updateTime=1792983064574, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1321430006727820106, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425656810951355, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1321430006727820107, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425656810951355, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1040, endPage=1045, ext={EN=ArticleExt(id=1321425713555681710, articleId=1321425711697605037, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Research progress in the mechanism and clinical application of the antidepressant Shenge Bushen Capsules, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Depression is a major global public health challenge with a complex pathogenesis. Current treatment options have limitations in terms of onset of action, side effects, and relapse prevention. Shenge Bushen Capsules has demonstrated reliable efficacy and a favorable safety profile in treating mild to moderate depression characterized by deficiency of both qi and yin, and insufficiency of kidney qi. This article analyzed the pathogenesis of depression and systematically reviewed the formulation theory, pharmacodynamic mechanisms, and clinical applications of Shenge Bushen Capsules, aiming to provide a theoretical basis for further research and clinical promotion of this preparation.

, authors=Hai-shan ZHANG, Hui-juan DONG, ZAKIYAGUL Gujahmat, Wen-hui LI, Juan HAO, Shi-xian HU, Zhao-jun YANG^*, authorsList=Hai-shan ZHANG, Hui-juan DONG, ZAKIYAGUL Gujahmat, Wen-hui LI, Juan HAO, Shi-xian HU, Zhao-jun YANG, authorCompany=null, correspAuthors=Zhao-jun YANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1321425713807339951, articleId=1321425711697605037, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=抗抑郁药参葛补肾胶囊的作用机制及临床应用研究进展, columnId=1236330553964810454, journalTitle=中国新药杂志, columnName=综述, runingTitle=null, highlight=null, articleAbstract=

抑郁症是全球范围内的重要公共卫生挑战，其发病机制复杂，现有治疗方案在起效时间、不良反应和预防复发等方面存在局限性。参葛补肾胶囊在治疗“气阴两虚、肾气不足”型轻中度抑郁症方面，显示出疗效确切和安全性良好的优势。本文通过分析抑郁症的病机基础，系统综述参葛补肾胶囊的组方理论、药效作用机制及临床应用进展，以期为该药的深入研究与临床推广应用提供理论支持。

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张海珊，女，本科，药师中级，主要从事中药创新药物研发。E-mail: haishan66666@126.com。

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张海珊，女，本科，药师中级，主要从事中药创新药物研发。E-mail: haishan66666@126.com。

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