Article(id=1321425638033052317, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425625915707977, articleNumber=null, orderNo=null, doi=10.20251/j.cnki.1003-3734.2026.09.014, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1751558400000, acceptedDateStr=2025-07-04, onlineDate=1792982023007, onlineDateStr=2026-10-26, pubDate=1778774400000, pubDateStr=2026-05-15, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792982023007, onlineIssueDateStr=2026-10-26, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792982023007, creator=13701087609, updateTime=1792982023007, updator=13701087609, issue=Issue{id=1321425625915707977, tenantId=1146029695717560320, journalId=1235980733773295621, year='2026', volume='35', issue='9', pageStart='897', pageEnd='1008', issueExtLink='null', onlineDate='null', pubDate='1778774400000', pubDateStr='2026-05-15', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792982020119, creator='13701087609', updateTime=1792983090252, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1321430114441745406, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425625915707977, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1321430114441745407, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425625915707977, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1002, endPage=1008, ext={EN=ArticleExt(id=1321425638200824478, articleId=1321425638033052317, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Association of potential inappropriate medication and falls among the elderly in the medical-nursing integration community, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To investigate the relationship between potentially inappropriate medication (PIM) and falls among the elderly in the medical-nursing integration community, and to provide a basis for fall prevention in the elderly.
Methods: A retrospective study was conducted. General information of the participants was collected, including basic information, disease conditions, medication use, various assessment records, and records of fall events. PIM screening was performed using the criteria of potentially inappropriate medications for older adults in China (2017). Statistical analyses were performed using R 4.3.0. Depending on the data type, t-tests, non-parametric rank sum test, or chi-square test was used, and logistic regression was used to analyze the relationship between various risk factors and falls.
Results: A total of 1 153 elderly individuals from the medical-nursing integration community were enralled and divided into two groups based on the presence of falls between January 2022 and June 2024: the fall group (n=290) and the non-fall group (n=863). Multivariate Logistic regression analysis showed that increased age, the presence of pain, anxiety and depression, and an increased number of psychotropic PIMs, endocrine PIMs, and NSAID PIMs were independent risk factors for falls (P<0.05), whereas a higher education level was a protective factor against falls (P<0.05).
Conclusion: An increased number of endocrine PIMs, NSAID PIMs, and psychotropic PIMs is closely associated with falls in the elderly. Clinicians should promote rational drug use, reduce the types and numbers of PIMs, and thus lower the risk of falls in this population.
, authors=Qiu-ya YANG, Xia LIU
*, authorsList=Qiu-ya YANG, Xia LIU, authorCompany=null, correspAuthors=Xia LIU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1321425638444094111, articleId=1321425638033052317, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=医养结合社区老年人潜在不适当用药与跌倒的相关性研究, columnId=1236331163573342670, journalTitle=中国新药杂志, columnName=药物安全与合理应用, runingTitle=null, highlight=null, articleAbstract=
目的： 探讨医养结合社区老年人潜在不适当用药（potentially inappropriate medication, PIM）与跌倒的关系，为预防老年人跌倒提供依据。
方法： 采取回顾性研究，收集研究对象一般资料，包括基本信息、疾病情况、用药情况，各项评估记录及跌倒不良事件记录等，以《中国老年人潜在不适当用药判断标准（2017年版）》为依据，进行老年人PIM筛查。采用R 4.3.0统计分析软件，依据数据类型采用t检验、非参数秩和检验或χ2检验。使用Logistic回归分析各项风险因素与跌倒之间的关系。
结果： 纳入医养结合社区内的老年人1 153例，根据2022年1月—2024年6月之间有无发生跌倒分为两组：跌倒组（n=290）和非跌倒组（n=863）。多因素Logistic回归分析结果显示，年龄增加，伴有疼痛、焦虑抑郁以及服用精神类PIM、内分泌类PIM、非甾体抗炎镇痛药PIM数量增加是医养结合社区老年人跌倒的独立危险因素（P<0.05），高学历是医养结合社区老年人跌倒的保护因素（P<0.05）。
结论： 内分泌类、非甾体抗炎镇痛药、精神类PIM数量增加与老年人跌倒密切相关，临床医师应加强合理用药，减少PIM用药种类与数量，降低老年人跌倒风险。
, authors=杨秋娅, 刘夏
*, authorsList=杨秋娅, 刘夏, authorCompany=null, correspAuthors=刘夏, authorNote=
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杨秋娅，女，主管药师，硕士，主要从事临床药学工作。E-mail: yangqy35@tkhealthcare.com。
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杨秋娅，女，主管药师，硕士，主要从事临床药学工作。E-mail: yangqy35@tkhealthcare.com。
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