Article(id=1321425637378732969, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425597998420385, articleNumber=null, orderNo=null, doi=10.20251/j.cnki.1003-3734.2026.08.014, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1768406400000, acceptedDateStr=2026-01-15, onlineDate=1792982022851, onlineDateStr=2026-10-26, pubDate=1777478400000, pubDateStr=2026-04-30, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792982022851, onlineIssueDateStr=2026-10-26, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792982022851, creator=13701087609, updateTime=1792982022851, updator=13701087609, issue=Issue{id=1321425597998420385, tenantId=1146029695717560320, journalId=1235980733773295621, year='2026', volume='35', issue='8', pageStart='785', pageEnd='896', issueExtLink='null', onlineDate='null', pubDate='1777478400000', pubDateStr='2026-04-30', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792982013463, creator='13701087609', updateTime=1792983113439, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1321430211678290797, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425597998420385, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1321430211678290798, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425597998420385, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=889, endPage=896, ext={EN=ArticleExt(id=1321425637584253866, articleId=1321425637378732969, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=A multicenter retrospective study based on medical records: clinical use of Xiangju Tablets in a pediatric population, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To evaluate the efficacy and safety of chamomile tablets in the treatment of pediatric otolaryngological diseases and explore its clinical application characteristics.
Methods: A retrospective analysis was conducted on medical records of children aged 1~14 years who were prescribed chamomile tablets at multiple hospitals in Guangdong Province and Xinjiang Uygur Autonomous Region between October 2015 and October 2024. Data including demographic information, clinical diagnoses, medication details (dosage, frequency, and duration), changes in clinical symptoms before and after treatment, and relevant laboratory test results were collected. Statistical analysis was performed using SAS 9.4 software.
Results: A total of 7 485 patients were included, with school-aged and preschool-aged children accounting for 83.7% of the cohort. Xiangju Tablets were primarily used for the treatment of pediatric allergic rhinitis (3 075 cases), pediatric sinusitis (1 291 cases), chronic tonsillitis and adenoid-related diseases (997 cases), as well as chronic rhinitis, nasopharyngitis, and pharyngitis (1 836 cases). The most common regimen was 1~2 tablets administered three times daily. The combination use rate of Xiangju Tablets reached 96.77%, and it is often combined with antihistamines and corticosteroids to enhance therapeutic efficacy. Laboratory findings indicated improvements in liver function and immune parameters. No serious adverse events were observed during the study period.
Conclusion: Xiangju Tablets demonstrate favorable efficacy in the treatment of pediatric otolaryngological diseases. Overall, this drug exhibits a good safety profile and represent an effective therapeutic option for children with otolaryngological conditions, showing promising clinical potential. However, the current data are insufficient to fully confirm its independent efficacy and specific role in combination therapy, and its clinical application value still needs to be further verified by higher-quality studies.
, authors=Yun-song AN
1, Zhi-guo HAN
2, *, Yi-lin HAN
1, Wei TENG
2, Juan-zhi ZHAO
3, Yi-shen CHEN
3, Yang-jing-ting LUO
4, Yi-ni LUO
5, Lu-chuan ZHAN
1, authorsList=Yun-song AN, Zhi-guo HAN, Yi-lin HAN, Wei TENG, Juan-zhi ZHAO, Yi-shen CHEN, Yang-jing-ting LUO, Yi-ni LUO, Lu-chuan ZHAN, authorCompany=null, correspAuthors=Zhi-guo HAN, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1321425637915603883, articleId=1321425637378732969, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=基于真实世界的多中心回顾性研究——香菊片在儿童耳鼻喉相关疾病中的临床应用, columnId=1236331163573342670, journalTitle=中国新药杂志, columnName=药物安全与合理应用, runingTitle=null, highlight=null, articleAbstract=
目的： 评估香菊片在治疗儿童耳鼻喉相关疾病中的疗效与安全性，并探讨其临床应用特点。
方法： 回顾性收集2015年10月—2024年10月期间，在广东省及新疆维吾尔自治区多家医院就诊的1~14岁患儿处方中包含香菊片的病历资料。收集信息包括人口学资料、临床诊断、香菊片的用药情况、治疗前后临床症状变化以及相应实验室检查结果，采用SAS 9.4统计软件进行统计分析。
结果： 共纳入7 485例患儿，学龄期和学龄前期儿童占83.7%。香菊片在儿童人群中主要用于治疗儿童变应性鼻炎（3 075例）、儿童鼻窦炎（1 291例）、扁桃体炎和腺样体慢性疾病（997例）以及慢性鼻炎、鼻咽炎和咽炎（1 836例）；香菊片主要以每日3次（tid）的频次使用，单次剂量以1~2片为主。香菊片联合用药情况达到了96.77%，常与抗组胺药、皮质激素类药物联合使用，增强疗效。实验室检查结果显示，香菊片治疗后儿童肝功能、免疫指标等有所改善。未发现严重不良事件。
结论： 总体而言，香菊片具有较高的安全性，为儿童耳鼻喉相关疾病提供了治疗选择，具有良好的临床应用前景。但现有数据还无法充分证实其独立疗效及联合用药中的具体作用，其临床应用价值仍须更高质量研究进一步验证。
, authors=安云崧
1, 韩治国
2, *, 韩依琳
1, 滕威
2, 赵娟芝
3, 陈奕伸
3, 罗杨婧婷
4, 罗懿妮
5, 詹陆川
1, authorsList=安云崧, 韩治国, 韩依琳, 滕威, 赵娟芝, 陈奕伸, 罗杨婧婷, 罗懿妮, 詹陆川, authorCompany=null, correspAuthors=韩治国, authorNote=
安云崧，男，博士，主治医师，研究方向：慢性鼻炎（包括过敏性鼻炎、血管运动性鼻炎）、慢性鼻窦炎、鼻息肉、鼻腔鼻窦肿瘤、鼻咽相关疾病的诊治以及等离子微创治疗成人及儿童鼾症。E-mail: anyunsong@126.com。
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* 韩治国，简介如上所示。
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安云崧，男，博士，主治医师，研究方向：慢性鼻炎（包括过敏性鼻炎、血管运动性鼻炎）、慢性鼻窦炎、鼻息肉、鼻腔鼻窦肿瘤、鼻咽相关疾病的诊治以及等离子微创治疗成人及儿童鼾症。E-mail: anyunsong@126.com。
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安云崧，男，博士，主治医师，研究方向：慢性鼻炎（包括过敏性鼻炎、血管运动性鼻炎）、慢性鼻窦炎、鼻息肉、鼻腔鼻窦肿瘤、鼻咽相关疾病的诊治以及等离子微创治疗成人及儿童鼾症。E-mail: anyunsong@126.com。
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