Article(id=1321425608354153364, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425569611362746, articleNumber=null, orderNo=null, doi=10.20251/j.cnki.1003-3734.2026.07.015, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1769097600000, acceptedDateStr=2026-01-23, onlineDate=1792982015931, onlineDateStr=2026-10-26, pubDate=1776182400000, pubDateStr=2026-04-15, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792982015931, onlineIssueDateStr=2026-10-26, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792982015931, creator=13701087609, updateTime=1792982015931, updator=13701087609, issue=Issue{id=1321425569611362746, tenantId=1146029695717560320, journalId=1235980733773295621, year='2026', volume='35', issue='7', pageStart='673', pageEnd='784', issueExtLink='null', onlineDate='null', pubDate='1776182400000', pubDateStr='2026-04-15', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792982006695, creator='13701087609', updateTime=1792983136833, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1321430309837587328, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425569611362746, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1321430309837587329, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425569611362746, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=780, endPage=784, ext={EN=ArticleExt(id=1321425610048652182, articleId=1321425608354153364, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Successful correction of perioperative hypoalbuminemia with recombinant human albumin injection (Oryza Sativa) in a patient with allergy to human serum albumin: a case report, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=

This article reports the case of a 70-year-old female patient scheduled for surgical intervention due to a space-occupying lesion at the distal common bile duct. The patient presented with severe allergic reactions to plasma-derived human serum albumin (pHSA), precluding its use for correcting hypoalbuminemia. Following informed consent, recombinant human albumin injection (Oryza Sativa) (OsrHSA) was administered as an alternative. The patient received a total of 70 g OsrHSA preoperatively in divided infusions, and her serum albumin level increased from 29.1 g·L^-1 to 37.3 g·L^-1 without adverse events. She subsequently underwent laparoscopic pancreaticoduodenectomy without complications. OsrHSA was also administered multiple times postoperatively, and no allergic reactions were observed. This case represented the successful application of OsrHSA as a safe alternative to pHSA in perioperative management for complex surgery. To the authors' knowledge, no similar reports have been published to date. This provides a new therapeutic avenue for patients with contraindications to human serum albumin, suggesting that plant-derived recombinant human albumin represents a safe and effective alternative.

, authors=Diligeer·TAYIER^{1, 2}, Xian QIN^{1, 2}, Ru-fang LIAO³, Zhi-yong YANG^{1, 2, *}, authorsList=Diligeer·TAYIER, Xian QIN, Ru-fang LIAO, Zhi-yong YANG, authorCompany=null, correspAuthors=Zhi-yong YANG, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1321425610296116119, articleId=1321425608354153364, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=重组人白蛋白注射液（水稻）成功纠正人血白蛋白过敏患者围手术期低蛋白血症的1例报告, columnId=1236331163573342670, journalTitle=中国新药杂志, columnName=药物安全与合理应用, runingTitle=null, highlight=null, articleAbstract=

本文报道了1例70岁女性患者，因“胆总管下端占位性病变”拟行手术治疗，但因对人血白蛋白严重过敏，无法通过人血白蛋白纠正低白蛋白血症。经患者及家属知情同意后，使用重组人白蛋白注射液（水稻）进行治疗。患者在术前分次输注70 g后，人血白蛋白水平由29.1 g·L^-1提升至37.3 g·L^-1，且无任何不良反应，顺利接受腹腔镜下胰十二指肠切除术。术后多次使用重组人白蛋白注射液（水稻），亦未发生过敏反应。本病例报告报道了重组人白蛋白注射液（水稻）作为血浆来源白蛋白的安全替代方案，及其在复杂外科围术期管理中的成功应用，笔者迄今未见国内外相关报道，这为存在人血白蛋白禁忌证的患者提供了新的治疗路径，即植物来源重组人白蛋白不失为一种安全、有效的关键替代方案。

, authors=迪丽尼格尔·塔依尔^{1, 2}, 秦弦^{1, 2}, 廖如芳³, 杨智勇^{1, 2, *}, authorsList=迪丽尼格尔·塔依尔, 秦弦, 廖如芳, 杨智勇, authorCompany=null, correspAuthors=杨智勇, authorNote=, correspAuthorsNote=, copyrightStatement=null, copyrightOwner=《中国新药杂志》有限公司, extLink=null, articleAbsUrl=null, sourceXml=4VlfbBU4NncCzfgOPCndQQ==, magXml=yOCKqcaShE3dM0Y8vX1PNQ==, pdfUrl=null, pdf=bPrFRlDRF4dYs/1DQleS7Q==, pdfFileSize=3020604, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=wgBKHldSVyxpJg/qHnp8FQ==, mapNumber=null, fund=null)}, authors=[Author(id=1321425610921067426, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425608354153364, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=2018305231004@whu.edu.cn, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425611004953509, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425608354153364, authorId=1321425610921067426, language=EN, stringName=Diligeer·TAYIER, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=^{1, 2}, address=¹Department of Hepatobiliary and Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430000, China
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²湖北省肝胆胰疾病微创诊治临床医学研究中心，武汉 430000, bio={"content":"

迪丽尼格尔·塔依尔，女，硕士研究生，研究方向：胰腺疾病的发病机制与诊治研究。联系电话：（027）67814315，E-mail: 2018305231004@whu.edu.cn。

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迪丽尼格尔·塔依尔，女，硕士研究生，研究方向：胰腺疾病的发病机制与诊治研究。联系电话：（027）67814315，E-mail: 2018305231004@whu.edu.cn。

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