Article(id=1236731784700949334, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236731777142804746, articleNumber=null, orderNo=null, doi=10.20251/j.cnki.1003-3734.2025.17.008, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1734451200000, acceptedDateStr=2024-12-18, onlineDate=1772789434838, onlineDateStr=2026-03-06, pubDate=1757865600000, pubDateStr=2025-09-15, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1772789434838, onlineIssueDateStr=2026-03-06, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1772789434838, creator=13701087609, updateTime=1772789434838, updator=13701087609, issue=Issue{id=1236731777142804746, tenantId=1146029695717560320, journalId=1235980733773295621, year='2025', volume='34', issue='17', pageStart='1793', pageEnd='1904', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=0, createTime=1772789433036, creator=13701087609, updateTime=1772801868692, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1236783936152596961, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236731777142804746, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1236783936152596962, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236731777142804746, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=1839, endPage=1844, ext={EN=ArticleExt(id=1236731784927441758, articleId=1236731784700949334, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Key points and considerations of clinical study design for medication timing, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=

The medication timing is an important factor affecting the clinical efficacy of drugs. Selecting the right medication timing is the key to ensure the full play of drug efficacy, as well as standardized and precise medication practices in clinical settings. Although some scholars have carried out relevant clinical studies on the medication timing, there remains a lack of systematic review and summary of its important research significance and key points of scheme design. This paper systematically discusses the concept of medication timing, research significance, understanding of traditional Chinese medicine, types of research design and key methodological points, aiming to clarify the design ideas for clinical research on medication timing, and focus on analyzing the similarities and differences, as well as key design points of different types of clinical studies. This article provides methodological guidance for timely and precise medication in clinical practice and effectively promotes the standardization and accuracy of clinical drug use.

, correspAuthors=Xin-xing LAI, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, authorCompany=null, fund=null, authors=null, authorsList=Xiang-yi ZHENG, Gen-ming ZHANG, Zi-yu TIAN, Ying GAO, Xin-xing LAI), CN=ArticleExt(id=1236731785845994379, articleId=1236731784700949334, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=针对用药时机的临床研究设计要点与思考, columnId=1236331741447778310, journalTitle=中国新药杂志, columnName=药物临床试验规范与进展专栏, runingTitle=null, highlight=null, articleAbstract=

用药时机是影响药物临床疗效的重要因素，选择恰当的用药时机是确保药效充分发挥和临床规范、精准用药的关键。目前已有学者针对用药时机开展了相关临床研究，但对于其重要研究意义及方案设计要点缺乏系统梳理与总结。本文就用药时机的概念、研究意义、中医药认识、研究设计类型及方法学要点等方面展开系统论述，旨在厘清针对用药时机的临床研究设计思路，重点剖析不同类型临床研究的异同与设计要点，为临床实践中适时、精准用药提供方法学指导，有力促进临床用药的规范性与精准性。

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郑湘宜，女，博士研究生，研究方向：中医药防治脑血管病。E-mail：z7x77y777@163.com。

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郑湘宜，女，博士研究生，研究方向：中医药防治脑血管病。E-mail：z7x77y777@163.com。

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