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Dictamni cortex is the dried root bark of the Dictamnus L. in the Rutaceae family. It contains alkaloids, limonoids, phenylpropanoids, flavonoids, et al. Based on summarization of its chemical components, pharmacological effects and toxicity, and according to the concept of traditional Chinese medicine quality marker (Q-marker), the Q-markers of Dictamni cortex were predicted from the aspects of genetic relationship and measurability of components, traditional efficacy, traditional property, different producing areas and collecting periods, and component contents under different ultraviolet radiation intensities. γ-fagarine, limonin, dictamnine, obacunone and fraxinellone can be used as Q-markers of Dictamni cortex, which provide a scientific reference for the establishment of quality standards.
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白鲜皮为芸香科白鲜属植物白鲜(Dictamnus dasycarpus Turcz.)的干燥根皮,已发现含有生物碱类、柠檬苦素类、苯丙素类、黄酮类等成分。本文在对白鲜皮化学成分、药理作用和毒性进行综述的基础上,围绕中药质量标志物(Q-marker)概念,从植物亲缘学和成分可测性、传统药效、传统药性、产地和采收时期及不同紫外辐射强度下成分含量等方面对白鲜皮Q-marker成分进行预测分析,发现γ-崖椒碱、柠檬苦素、白鲜碱、黄柏酮和梣酮可作为白鲜皮Q-marker指标,以期为白鲜皮科学质量标准的建立提供参考。
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刘新月,女,硕士研究生,主要从事中药药性理论与应用研究。E-mail: 2460169059@qq.com。
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