Article(id=1236369016839795205, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236369013111050820, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1667404800000, acceptedDateStr=2022-11-03, onlineDate=1772702944239, onlineDateStr=2026-03-05, pubDate=1694707200000, pubDateStr=2023-09-15, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1772702944239, onlineIssueDateStr=2026-03-05, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1772702944239, creator=13701087609, updateTime=1772702944239, updator=13701087609, issue=Issue{id=1236369013111050820, tenantId=1146029695717560320, journalId=1235980733773295621, year='2023', volume='32', issue='17', pageStart='1697', pageEnd='1800', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1772702943351, creator=13701087609, updateTime=1772703317941, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1236370584322495028, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236369013111050820, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1236370584326689333, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236369013111050820, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=1697, endPage=1702, ext={EN=ArticleExt(id=1236369017393443371, articleId=1236369016839795205, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=The product design ideas of traditional Chinese medicine based on innovative methods, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=

The product production chain of traditional Chinese medicine suffers from low product quality, low efficiency transformation, and insufficient innovation capability, and there lacks complete innovation process chain to address product-independent R&D innovation. For the process chain of Chinese medicine product development, this paper analyzes and discusses the application of Chinese medicine product innovation methods by combining five methods: quality function development (QFD), inventive problem solving theory Teoriya Resheniya Izobreatatelskikh Zadatch (TRIZ), quality by design (QbD), design of experiments (DOE), and data envelopment analysis (DEA). Firstly, QFD is applied to determine the direction of innovation by comprehensive analysis of user needs and actual situation; secondly, TRIZ is applied to analyze and solve the contradictions to be solved by the product, propose solutions and combine QbD and DOE for experimental design and verification; finally, DEA is applied to allocate resources to optimize the efficiency. Combining innovation methods to develop and design Chinese medicine products can develop core technologies and equipment with independent intellectual property rights, effectively improve the quality and effectiveness of Chinese medicine products transformation, which is meaningful for the development of Chinese medicine products.

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传统中药产品生产链存在着产品品质低、效能转化低、创新能力不足等问题,没有完整的创新过程链以解决产品自主研发创新。针对中药产品开发过程链,本文结合质量功能展开(quality function development, QFD)、发明问题解决理论(teoriya resheniya izobreatatelskikh zadatch, TRIZ)、质量源于设计(quality by design, QbD)、实验设计(design of experiments, DOE)、数据包络分析(data envelopment analysis, DEA)这5种方法,对中药产品创新方法应用进行分析探讨。首先,运用QFD对用户需求和实际情况综合分析确定创新方向;其次,运用TRIZ对产品所需解决的矛盾进行分析,提出解决方案,并结合QbD和DOE进行实验设计和验证;最后,运用DEA资源分配使效率达到最优化。结合创新方法对中药产品开发设计,能够研发具有自主知识产权的核心技术和装备,有效提升中药产品品质与效能转化,对于中药产品的发展有着良好的意义。

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朱卫丰,女,教授,博士,主要从事中药新剂型与新技术研究。联系电话:(0791)87118658,E-mail:
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陈丽华,女,教授,博士,博士生导师,主要从事中药创新方法与实践研究。E-mail:

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基于创新方法中药产品设计思路
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陈丽华 , 张永 , 黄诗雨 , 朱卫丰 , 姜佳恩 , 马伊宁 , 单雅慧
中国新药杂志 | 新药述评与论坛 2023,32(17): 1697-1702
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中国新药杂志 | 新药述评与论坛 2023, 32(17): 1697-1702
基于创新方法中药产品设计思路
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陈丽华 , 张永, 黄诗雨, 朱卫丰 , 姜佳恩, 马伊宁, 单雅慧
作者信息
  • 江西中医药大学现代中药制剂教育部重点实验室,南昌 330004
  • 陈丽华,女,教授,博士,博士生导师,主要从事中药创新方法与实践研究。E-mail:

通讯作者:

朱卫丰,女,教授,博士,主要从事中药新剂型与新技术研究。联系电话:(0791)87118658,E-mail:
The product design ideas of traditional Chinese medicine based on innovative methods
Li-hua CHEN , Yong ZHANG, Shi-yu HUANG, Wei-feng ZHU , Jia-en JIANG, Yi-ning MA, Ya-hui SHAN
Affiliations
  • Key Laboratory of the Ministry of Education, Ministry of Education, Jiangxi University of Chinese Medicine, Nanchang 330004, China
出版时间: 2023-09-15
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传统中药产品生产链存在着产品品质低、效能转化低、创新能力不足等问题,没有完整的创新过程链以解决产品自主研发创新。针对中药产品开发过程链,本文结合质量功能展开(quality function development, QFD)、发明问题解决理论(teoriya resheniya izobreatatelskikh zadatch, TRIZ)、质量源于设计(quality by design, QbD)、实验设计(design of experiments, DOE)、数据包络分析(data envelopment analysis, DEA)这5种方法,对中药产品创新方法应用进行分析探讨。首先,运用QFD对用户需求和实际情况综合分析确定创新方向;其次,运用TRIZ对产品所需解决的矛盾进行分析,提出解决方案,并结合QbD和DOE进行实验设计和验证;最后,运用DEA资源分配使效率达到最优化。结合创新方法对中药产品开发设计,能够研发具有自主知识产权的核心技术和装备,有效提升中药产品品质与效能转化,对于中药产品的发展有着良好的意义。

中药产品  /  过程链  /  创新方法  /  发明问题解决理论  /  质量功能展开  /  质量源于设计  /  实验设计  /  数据包络分析

The product production chain of traditional Chinese medicine suffers from low product quality, low efficiency transformation, and insufficient innovation capability, and there lacks complete innovation process chain to address product-independent R&D innovation. For the process chain of Chinese medicine product development, this paper analyzes and discusses the application of Chinese medicine product innovation methods by combining five methods: quality function development (QFD), inventive problem solving theory Teoriya Resheniya Izobreatatelskikh Zadatch (TRIZ), quality by design (QbD), design of experiments (DOE), and data envelopment analysis (DEA). Firstly, QFD is applied to determine the direction of innovation by comprehensive analysis of user needs and actual situation; secondly, TRIZ is applied to analyze and solve the contradictions to be solved by the product, propose solutions and combine QbD and DOE for experimental design and verification; finally, DEA is applied to allocate resources to optimize the efficiency. Combining innovation methods to develop and design Chinese medicine products can develop core technologies and equipment with independent intellectual property rights, effectively improve the quality and effectiveness of Chinese medicine products transformation, which is meaningful for the development of Chinese medicine products.

Chinese medicine products  /  process chain  /  innovation method  /  teoriya resheniya izobreatatelskikh zadatch  /  quality function development  /  quality by design  /  design of experiments  /  data envelopment analysis
陈丽华, 张永, 黄诗雨, 朱卫丰, 姜佳恩, 马伊宁, 单雅慧. 基于创新方法中药产品设计思路. 中国新药杂志, 2023 , 32 (17) : 1697 -1702 .
Li-hua CHEN, Yong ZHANG, Shi-yu HUANG, Wei-feng ZHU, Jia-en JIANG, Yi-ning MA, Ya-hui SHAN. The product design ideas of traditional Chinese medicine based on innovative methods[J]. Chinese Journal of New Drugs, 2023 , 32 (17) : 1697 -1702 .
  • 国家创新方法专项资助项目(2021IM010500)
  • 2022年度江西中医药大学研究生创新专项资助项目(JZYC22S67)
  • 江西中医药大学校级科技创新团队发展计划资助项目(CXTD-22004)
  • 大学生创新创业训练计划资助项目(X202310412158)
2023年第32卷第17期
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  • 首发时间:2026-03-05
  • 出版时间:2023-09-15
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  • 录用日期:2022-11-03
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国家创新方法专项资助项目(2021IM010500)
2022年度江西中医药大学研究生创新专项资助项目(JZYC22S67)
江西中医药大学校级科技创新团队发展计划资助项目(CXTD-22004)
大学生创新创业训练计划资助项目(X202310412158)
作者信息
    江西中医药大学现代中药制剂教育部重点实验室,南昌 330004

通讯作者:

朱卫丰,女,教授,博士,主要从事中药新剂型与新技术研究。联系电话:(0791)87118658,E-mail:
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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
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Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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