Article(id=1236369014822334791, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236369011668210230, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1665072000000, acceptedDateStr=2022-10-07, onlineDate=1772702943759, onlineDateStr=2026-03-05, pubDate=1692028800000, pubDateStr=2023-08-15, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1772702943759, onlineIssueDateStr=2026-03-05, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1772702943759, creator=13701087609, updateTime=1772702943759, updator=13701087609, issue=Issue{id=1236369011668210230, tenantId=1146029695717560320, journalId=1235980733773295621, year='2023', volume='32', issue='15', pageStart='1489', pageEnd='1592', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1772702943007, creator=13701087609, updateTime=1772703232203, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1236370224711258643, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236369011668210230, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1236370224711258644, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236369011668210230, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=1489, endPage=1494, ext={EN=ArticleExt(id=1236369015090770268, articleId=1236369014822334791, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Evaluation on the strategy layout of nilotinib patents, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To evaluate the patent protection strategies of nilotinib, and to provide the reference for R&D of domestic pharmaceutical enterprises.
Methods: The patent website database Patsnap was searched, and the patent technology characteristics of nilotinib were summarized.
Results: Novartis has successfully protected the core patents of nilotinib, but the protection is not sufficient for external patents.
Conclusion: Novartis's patent protection strategies associated with nilotinib are useful references for innovation drugs and generics enterprises.
, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, authorCompany=null, fund=null, authors=null, authorsList=Lei YANG, Li DONG), CN=ArticleExt(id=1236369015371788659, articleId=1236369014822334791, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=尼洛替尼专利布局策略分析, columnId=1236331162679955859, journalTitle=中国新药杂志, columnName=新药述评与论坛, runingTitle=null, highlight=null, articleAbstract=
目的: 分析尼洛替尼的专利申请与保护策略,为国内制药企业的药物研发提供参考。
方法: 查询专利检索数据库智慧芽(Patsnap)等的尼洛替尼专利相关文献,总结分析尼洛替尼的专利技术特点。
结果: 诺华原研公司成功保护了尼洛替尼的核心专利,而外围专利保护不够严密。
结论: 诺华公司的尼洛替尼药物专利布局策略对原研药和仿制药公司都有一定的参考价值。
, correspAuthors=null, authorNote=null, correspAuthorsNote=
, copyrightStatement=null, copyrightOwner=《中国新药杂志》有限公司, extLink=null, articleAbsUrl=null, sourceXml=Lt133wqG6X6uLJ9L6VJVlA==, magXml=BwEmdqbe1MpAig0R+6tv8Q==, pdfUrl=null, pdf=8SQrB92Y81hhpZXEmU2PwA==, pdfFileSize=25429246, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=o49lBiGo6se7EjHrl6/Krw==, mapNumber=null, authorCompany=null, fund=null, authors=
, authorsList=杨磊, 董丽)}, authors=[Author(id=1236369015740887447, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=larry0920@126.com, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1236369015845745057, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, authorId=1236369015740887447, language=EN, stringName=Lei YANG, firstName=Lei, middleName=null, lastName=YANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=College of Business Administration, Shenyang Pharmaceutical University, Shenyang 110016, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1236369015942214058, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, authorId=1236369015740887447, language=CN, stringName=杨磊, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=沈阳药科大学工商管理学院,沈阳 110016, bio={"content":"
杨磊,男,硕士研究生,主要从事药物专利分析研究。E-mail: larry0920@126.com。
"}, bioImg=null, bioContent=
杨磊,男,硕士研究生,主要从事药物专利分析研究。E-mail: larry0920@126.com。
, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1236369015610864013, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, xref=null, ext=[AuthorCompanyExt(id=1236369015623446926, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, companyId=1236369015610864013, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=College of Business Administration, Shenyang Pharmaceutical University, Shenyang 110016, China), AuthorCompanyExt(id=1236369015627641231, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, companyId=1236369015610864013, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=沈阳药科大学工商管理学院,沈阳 110016)])]), Author(id=1236369016047071666, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=sydongli@163.com, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1236369016177095107, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, authorId=1236369016047071666, language=EN, stringName=Li DONG, firstName=Li, middleName=null, lastName=DONG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=College of Business Administration, Shenyang Pharmaceutical University, Shenyang 110016, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1236369016273564105, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, authorId=1236369016047071666, language=CN, stringName=董丽, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=沈阳药科大学工商管理学院,沈阳 110016, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1236369015610864013, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, xref=null, ext=[AuthorCompanyExt(id=1236369015623446926, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, companyId=1236369015610864013, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=College of Business Administration, Shenyang Pharmaceutical University, Shenyang 110016, China), AuthorCompanyExt(id=1236369015627641231, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, companyId=1236369015610864013, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=沈阳药科大学工商管理学院,沈阳 110016)])])], keywords=[Keyword(id=1236369016441336279, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, language=EN, orderNo=1, keyword=nilotinib), Keyword(id=1236369016567165416, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, language=EN, orderNo=2, keyword=patent protection), Keyword(id=1236369016692994550, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, language=EN, orderNo=3, keyword=application strategy), Keyword(id=1236369016818823681, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, language=EN, orderNo=4, keyword=patent analysis), Keyword(id=1236369016940458514, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, language=CN, orderNo=1, keyword=尼洛替尼), Keyword(id=1236369017129202201, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, language=CN, orderNo=2, keyword=专利保护), Keyword(id=1236369017234059811, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, language=CN, orderNo=3, keyword=申请策略), Keyword(id=1236369017410220590, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, language=CN, orderNo=4, keyword=专利分析)], refs=null, funds=null, companyList=[AuthorCompany(id=1236369015610864013, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, xref=null, ext=[AuthorCompanyExt(id=1236369015623446926, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, companyId=1236369015610864013, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=College of Business Administration, Shenyang Pharmaceutical University, Shenyang 110016, China), AuthorCompanyExt(id=1236369015627641231, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236369014822334791, companyId=1236369015610864013, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=沈阳药科大学工商管理学院,沈阳 110016)])], figs=null, attaches=null, journal=Journal(id=1235980159023624194, delFlag=0, nameCn=中国新药杂志, nameEn=Chinese Journal of New Drugs, nameHistory1=null, nameHistory2=null, issn=1003-3734, eissn=null, cn=11-2850/R, coden=ZXZHA6, periodic=3, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=ohPEEN//Vz1tDT3ZBNTp4Q==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Journal of New Drugs, journalRemark=null, publicationField=null, createdTime=1772610233314, updatedTime=1772610649152, createdBy=18614031015, updatedBy=13701087609, firstLetterCn=C, firstLetterEn=C, subjectCode=Life Sciences, subjectName=null, subjectCodeEn=Life Sciences, subjectNameEn=null, picCn=ohPEEN//Vz1tDT3ZBNTp4Q==, picEn=f9WK9bvTM4guTmS/iGhOMg==, jcr=null, cjcr=null, exts=[JournalExt(id=1235981903275290962, language=CN, name=中国新药杂志, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1772610649174, updatedTime=1772610649174, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=http://draft.newdrug.cn/journalx_zgxy/authorLogOn.action, submissionEditorUrl=http://draft.newdrug.cn/journalx_zgxy/editorLogOn.action, submissionReviewUrl=http://draft.newdrug.cn/journalx_zgxy/expertLogOn.action, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1235981903338205523, language=EN, name=Chinese Journal of New Drugs, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1772610649189, updatedTime=1772610649189, createdBy=13701087609, updatedBy=13701087609, submissionGuidelinesUrl=, submissionAuthorUrl=http://draft.newdrug.cn/journalx_zgxy/authorLogOn.action, submissionEditorUrl=http://draft.newdrug.cn/journalx_zgxy/editorLogOn.action, submissionReviewUrl=http://draft.newdrug.cn/journalx_zgxy/expertLogOn.action, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1235980733773295621, websiteList=[Website(id=1235982099191222761, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1235980733773295621, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zgxyzz/CN, language=CN, createTime=1772610695884, createBy=18614031015, updateTime=1772610860397, updateBy=18614031015, name=中国新药杂志-中文, tplId=1146099689490845704, title=中国新药杂志, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1235983918629966444, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=articleTextType, value=kx, createTime=1772611129672, updateTime=1772611129672, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918604800617, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=banner, value=null, createTime=1772611129666, updateTime=1772611129666, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918655132271, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=grayFlag, value=0, createTime=1772611129678, updateTime=1772611129678, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918596412008, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=logo, value=https://castjournals.cast.org.cn/joweb/zgxyzz/CN/file/pic?fileId=W567vm71kFC7UhK9TSU6xw==, createTime=1772611129664, updateTime=1772611129664, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918667715185, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=minRunFlag, value=0, createTime=1772611129681, updateTime=1772611129681, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918617383531, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zgxyzz/CN/file/pic, createTime=1772611129669, updateTime=1772611129669, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918659326576, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=silenceFlag, value=0, createTime=1772611129679, updateTime=1772611129679, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918613189226, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1772611129668, updateTime=1772611129668, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918634160749, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=themeColor, value=null, createTime=1772611129673, updateTime=1772611129673, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918646743662, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=themeStyle, value=null, createTime=1772611129676, updateTime=1772611129676, creator=18614031015, updator=18614031015)]), Website(id=1235982099270914542, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1235980733773295621, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zgxyzz/EN, language=EN, createTime=1772610695903, createBy=18614031015, updateTime=1772610875891, updateBy=18614031015, name=中国新药杂志-英文, tplId=1146101810881728533, title=Chinese Journal of New Drugs, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1235983955829248630, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=articleTextType, value=kx, createTime=1772611138541, updateTime=1772611138541, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955804082803, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=banner, value=null, createTime=1772611138535, updateTime=1772611138535, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955854414457, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=grayFlag, value=0, createTime=1772611138547, updateTime=1772611138547, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955795694194, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=logo, value=https://castjournals.cast.org.cn/joweb/zgxyzz/EN/file/pic?fileId=W567vm71kFC7UhK9TSU6xw==, createTime=1772611138533, updateTime=1772611138533, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955866997371, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=minRunFlag, value=0, createTime=1772611138550, updateTime=1772611138550, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955820860021, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zgxyzz/EN/file/pic, createTime=1772611138539, updateTime=1772611138539, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955862803066, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=silenceFlag, value=0, createTime=1772611138549, updateTime=1772611138549, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955812471412, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1772611138537, updateTime=1772611138537, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955837637239, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=themeColor, value=null, createTime=1772611138543, updateTime=1772611138543, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955846025848, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=themeStyle, value=null, createTime=1772611138545, updateTime=1772611138545, creator=18614031015, updator=18614031015)])], journalTitle=中国新药杂志, weixinUrl=null, journalUrl=http://www.newdrug.cn/, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Journal of New Drugs, journalPhotoCn=ohPEEN//Vz1tDT3ZBNTp4Q==, journalPhotoEn=f9WK9bvTM4guTmS/iGhOMg==, journalFirstLetter=C, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false), detailUrlCn=https://castjournals.cast.org.cn/joweb/zgxyzz/CN/Y2023/V32/I15/1489, detailUrlEn=https://castjournals.cast.org.cn/joweb/zgxyzz/EN/Y2023/V32/I15/1489, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zgxyzz/CN/PDF/Y2023/V32/I15/1489, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zgxyzz/EN/PDF/Y2023/V32/I15/1489, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, reference=null)