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The aim of the article is to analyze the current research progress of COVID-19 vaccines in China and abroad based on patent data, and to make statistics on the main types and hot technologies, so as to provide reasonable suggestions for future vaccine research and development. Innojoy patent search engine and Baiten patent network were used to retrieve and analyze the patent data, and technology prediction was made according to the concept model of technology prediction. At present, the research hotspots of COVID-19 vaccines are mainly distributed in the technical fields related to the use of antigens, antibodies, peptides and genetic engineering. The research on COVID-19 vaccines in China mostly focuses on recombinant protein/epitope/polypeptide/subunit vaccines and nucleic acid vaccines, and the technical hotspots focus on antigen improvement techniques. The current research in the field of COVID-19 vaccines in the world and in China has made some progress, making the patent market active. The COVID-19 vaccine-related market and technical structure tend to enter a more developed stage.

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依据专利数据分析全球及我国目前在新型冠状病毒肺炎疫苗（简称新冠疫苗）领域的研究进展，对现有疫苗的主要类型和热点技术进行统计，为未来疫苗的研发提供合理建议。使用Innojoy专利搜索引擎和Baiten专利网进行专利数据检索，并利用技术预测概念模型进行技术预测。目前新冠疫苗的研究热点主要分布在利用抗原、抗体、肽类与基因工程相关技术的领域，我国对于新冠疫苗的研究多集中于重组蛋白/表位/多肽/亚单位疫苗与核酸疫苗，技术热点集中于抗原改进技术。全球及我国目前在新冠疫苗领域的研究已经取得了一些进展，且专利市场活跃，短期内新冠疫苗相关专利市场与技术格局有望趋于成熟。

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王冉，女，硕士研究生，主要从事药事管理研究。E-mail: w15849637572@163.com。

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王冉，女，硕士研究生，主要从事药事管理研究。E-mail: w15849637572@163.com。

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