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Chinese medicine has rich theoretical and practical experience in the treatment of blood stasis and the application of blood-activating and stasis-removing drugs. The widespread use of contemporary blood-activating and blood-stasis treatment methods has made an important contribution to the prevention and treatment of major diseases. However, the clinical application of blood-activating and stasis-transforming Chinese patent medicines still suffers from unclear application indications, efficacy, action characteristics, safety information, dose and course of treatment, etc. Safety issues such as bleeding caused by irrational use of drugs have been a concern in the industry. To provide traditional Chinese medicine practitioners, Western medicine practitioners, general practitioners and clinical pharmacists with general principles for the scientific, rational and standardized use of blood-activating and blood-stasis-removing proprietary Chinese medicines. This guideline writing group follows the evidence-based principles and makes reference to the current high-quality clinical evidence to develop the "Guidelines for Rational Use of Proprietary Chinese Medicines for Promoting Blood circulation and Removing Blood Stasis". The next part contains 18 varieties of blood-activating and stasis-transforming Chinese patent medicines and 26 recommendations, involving mainly cardiovascular and cerebrovascular diseases.

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中医药对血瘀证治疗和活血化瘀类药物的应用具有丰富的理论实践经验，当代活血化瘀治法的广泛应用为重大疾病防治作出了重要贡献。但活血化瘀类中成药的临床应用仍存在应用指征、疗效、作用特点、安全性信息、剂量和疗程等尚不明确的问题，由于不合理用药导致的出血等安全性问题一直受到行业关注。为向中医师、西医师、全科医生及临床药学人员提供科学合理、规范使用活血化瘀中成药的一般原则，本指南编写组遵循循证原则，参考目前高质量临床证据，制定《活血化瘀类中成药合理用药指南》，其中下篇部分包含18项活血化瘀类中成药品种，26项推荐意见，涉及疾病主要为心脑血管科疾病。

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