Article(id=1236342821251240388, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236342820131361209, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1665590400000, acceptedDateStr=2022-10-13, onlineDate=1772696698725, onlineDateStr=2026-03-05, pubDate=1677513600000, pubDateStr=2023-02-28, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1772696698725, onlineIssueDateStr=2026-03-05, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1772696698725, creator=13701087609, updateTime=1772696698725, updator=13701087609, issue=Issue{id=1236342820131361209, tenantId=1146029695717560320, journalId=1235980733773295621, year='2023', volume='32', issue='4', pageStart='329', pageEnd='440', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1772696698458, creator=13701087609, updateTime=1772696766437, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1236343105318875204, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236342820131361209, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1236343105318875205, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236342820131361209, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=357, endPage=363, ext={EN=ArticleExt(id=1236342821435789767, articleId=1236342821251240388, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Exploration of the current situation of rational use of proprietary Chinese medicines in emergency department based on literature in CNKI database, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To assess the current situation of rational use of proprietary Chinese medicines in emergency department.
Methods: Subject search was carried out by using "rational drug use" OR "prescription analysis" OR "prescription review" AND "Chinese patent medicine" OR "traditional Chinese medicine injection" OR "injection" AND "emergency" in CNKI database, and all literatures from the establishment of the database to August 1, 2022 were sorted by literature source, publication year, author and institution. The literature was classified by region, age distribution of the study population, and irrational drug use, and bibliometrics was used to evaluate the rational use of proprietary Chinese medicines in emergency department.
Results: A total of 121 literature published in 65 journals were included. The research on the rational use of proprietary Chinese medicines in emergency department was on the rise, and researchers in East China were relatively more concerned about the rational use of proprietary Chinese medicines in emergency department. The total number of prescriptions in the included literature was 1 160 273, including 15 815 irrational prescriptions. Among them, non-conformant prescriptions, inappropriate prescriptions and extraordinary prescriptions accounted for 21.16%, 57.53% and 10.79%, respectively. The total number of emergency prescriptions of proprietary Chinese medicines for children (or infants) was 32 179, and the number of unreasonable prescriptions was 2 211. Among them, non-conformant prescriptions, inappropriate prescriptions and extraordinary prescriptions accounted for 16.46%, 30.48% and 50.57%, respectively. The irrational drug use in children mainly involved heat-clearing and expectorant Chinese patent medicines, and the irrational drug use was mainly off-label. The elderly in the emergency department mainly used proprietary Chinese medicines for promoting blood circulation and removing blood stasis, and the irrational drug use mainly involved repeated administration and inappropriate combination medication. The adverse reactions of proprietary Chinese medicines mainly involved skin tissue and digestive system symptoms, and related irrational drug use conditions included unsuitable combination medication, repeated medication, and unsuitable injection vehicles (or unsuitable route of administration or dosage form).
Conclusion: The number of studies on the rational use of proprietary Chinese medicines in the emergency department is limited and the quality is not high. In the future, it is urgent to formulate guidelines for the clinical use of proprietary Chinese medicines that are more suitable for emergency department, optimize the evaluation criteria, and lay the foundation for effectively promoting the rational and standardized application of proprietary Chinese medicines in the emergency department.
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方法： 以“合理用药”OR “处方分析”OR “处方点评”AND “中成药”OR “中药注射剂”OR “注射液”AND “急诊科”进行主题检索，检索中国知网（CNKI）数据库，从建库至2022年8月1日的所有文献，按文献来源、发表年份、作者及机构所属区域、研究人群年龄分布、不合理用药情况等对文献进行分类，应用文献计量学方法评估急诊科中成药的合理用药情况。
结果： 通过专业检索及手动剔除误纳入的文献，最终纳入急诊科中成药相关的文献121篇，共刊登在65种期刊上。整体上，文献发表数量呈上升趋势，来自华东地区的研究者相对更加关注急诊科中成药的合理用药情况。纳入文献总体处方总数为1 160 273，不合理处方15 815个。其中不适宜处方占比57.53%，不规范处方和超常处方分别占比21.16%和10.79%。儿童（或婴幼儿）急诊科中成药处方总数为32 179，不合理处方数量为2 211个。其中不规范处方、不适宜处方和超常处方分别占比16.46%，30.48%和50.57%。急诊科儿童不合理用药以清热类和祛痰类中成药为主，不合理用药以超说明书用药为主。急诊科老年人以活血化瘀类中成药为主，不合理用药情况以重复给药和联合用药不适宜为主。中成药不良反应以皮肤和消化系统症状为主，相关的不合理用药情况包括联合用药不适宜、重复用药、注射剂溶媒不适宜（或给药途径或剂型不适宜）。
结论： 中成药在急诊科合理用药的研究数量有限、质量不高，未来亟须制定急诊科的中成药临床使用指导原则，优化评判标准，为切实推动中成药在急诊科的合理规范应用奠定基础。
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, authorsList=马杭琨, 栗蕊, 李辰飞, 高洪阳, 高蕊, 李庆娜)}, authors=[Author(id=1236342822232707563, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=mariaquin@163.com, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1236342822316593646, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, authorId=1236342822232707563, language=EN, stringName=Hang-kun MA, firstName=Hang-kun, middleName=null, lastName=MA, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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1Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1236342822425645554, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, authorId=1236342822232707563, language=CN, stringName=马杭琨, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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1中国中医科学院西苑医院，北京 100091, bio={"content":"
马杭琨，女，博士研究生在读，主治医师，主要从事中医药临床研究。E-mail: mariaquin@163.com。
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马杭琨，女，博士研究生在读，主治医师，主要从事中医药临床研究。E-mail: mariaquin@163.com。
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2河南中医药大学第一附属医院，郑州 477150)])]), Author(id=1236342822761189887, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1236342822828298754, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, authorId=1236342822761189887, language=EN, stringName=Chen-fei LI, firstName=Chen-fei, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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3Institute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Key Laboratory of Clinical Research and Evaluation of Traditional Chinese Medicine, State Drug Administration, National Clinical Research Center for Cardiovascular Diseases of Traditional Chinese Medicine, Beijing 100091, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1236342822903796228, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, authorId=1236342822761189887, language=CN, stringName=李辰飞, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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3中国中医科学院西苑医院临床药理研究所，国家药品监督管理局中药临床研究与评价重点实验室，国家中医心血管病临床医学研究中心，北京 100091, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1236342822111072741, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, xref=3, ext=[AuthorCompanyExt(id=1236342822119461350, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, companyId=1236342822111072741, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3Institute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Key Laboratory of Clinical Research and Evaluation of Traditional Chinese Medicine, State Drug Administration, National Clinical Research Center for Cardiovascular Diseases of Traditional Chinese Medicine, Beijing 100091, China), AuthorCompanyExt(id=1236342822127849959, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, companyId=1236342822111072741, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3中国中医科学院西苑医院临床药理研究所，国家药品监督管理局中药临床研究与评价重点实验室，国家中医心血管病临床医学研究中心，北京 100091)])]), Author(id=1236342822970905096, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1236342823063179787, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, authorId=1236342822970905096, language=EN, stringName=Hong-yang GAO, firstName=Hong-yang, middleName=null, lastName=GAO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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1Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1236342823159648781, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, authorId=1236342822970905096, language=CN, stringName=高洪阳, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
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1中国中医科学院西苑医院，北京 100091, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1236342821918134745, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, xref=1, ext=[AuthorCompanyExt(id=1236342821926523354, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, companyId=1236342821918134745, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
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1中国中医科学院西苑医院，北京 100091)])]), Author(id=1236342823226757649, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1236342823323226645, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, authorId=1236342823226757649, language=EN, stringName=Rui GAO, firstName=Rui, middleName=null, lastName=GAO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 3, address=
1Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China
3Institute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Key Laboratory of Clinical Research and Evaluation of Traditional Chinese Medicine, State Drug Administration, National Clinical Research Center for Cardiovascular Diseases of Traditional Chinese Medicine, Beijing 100091, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1236342823386141207, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, authorId=1236342823226757649, language=CN, stringName=高蕊, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, 3, address=
1中国中医科学院西苑医院，北京 100091
3中国中医科学院西苑医院临床药理研究所，国家药品监督管理局中药临床研究与评价重点实验室，国家中医心血管病临床医学研究中心，北京 100091, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1236342821918134745, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, xref=1, ext=[AuthorCompanyExt(id=1236342821926523354, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, companyId=1236342821918134745, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
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1中国中医科学院西苑医院，北京 100091)]), AuthorCompany(id=1236342822111072741, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, xref=3, ext=[AuthorCompanyExt(id=1236342822119461350, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, companyId=1236342822111072741, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3Institute of Clinical Pharmacology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Key Laboratory of Clinical Research and Evaluation of Traditional Chinese Medicine, State Drug Administration, National Clinical Research Center for Cardiovascular Diseases of Traditional Chinese Medicine, Beijing 100091, China), AuthorCompanyExt(id=1236342822127849959, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, companyId=1236342822111072741, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3中国中医科学院西苑医院临床药理研究所，国家药品监督管理局中药临床研究与评价重点实验室，国家中医心血管病临床医学研究中心，北京 100091)])]), Author(id=1236342823470027292, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=liqingna789@163.com, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1236342823570690590, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1236342821251240388, authorId=1236342823470027292, language=EN, stringName=Qing-na LI, firstName=Qing-na, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
3, address=
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