Article(id=1236334168708281333, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236334167978472434, articleNumber=null, orderNo=null, doi=null, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1654272000000, acceptedDateStr=2022-06-04, onlineDate=1772694635798, onlineDateStr=2026-03-05, pubDate=1689350400000, pubDateStr=2023-07-15, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1772694635798, onlineIssueDateStr=2026-03-05, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1772694635798, creator=13701087609, updateTime=1772694635798, updator=13701087609, issue=Issue{id=1236334167978472434, tenantId=1146029695717560320, journalId=1235980733773295621, year='2023', volume='32', issue='13', pageStart='1281', pageEnd='1384', issueExtLink='null', onlineDate='null', pubDate='null', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=0, articleOrder=1, issueType=-1, specialIssue=null, createTime=1772694635624, creator=13701087609, updateTime=1772696111905, updator=13701087609, preIssue=null, nextIssue=null, ext={EN=IssueExt(id=1236340360004292707, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236334167978472434, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1236340360004292708, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1236334167978472434, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null}, startPage=1325, endPage=1335, ext={EN=ArticleExt(id=1236334168880247800, articleId=1236334168708281333, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Chemical constituents, pharmacological effects and clinical applications of Corydalis saxicola Bunting and predictive analysis on quality marker, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=

Corydalis saxicola Bunting mainly distributes in Guangxi, Guizhou and Yunnan, etc., and it is a genuine folk medicine in Guangxi Province. The chemical composition of Corydalis saxicola Bunting mainly contains alkaloids, flavonoids, steroids and so on. It has activities of liver protection, anti-tumor, and anti-oxidation, thus often used in the treatment of sore boils, hepatitis, liver cirrhosis, and liver cancer. The chemical constituents and pharmacological effects of Corydalis saxicola Bunting are summarized in this article, and the quality markers (Q-Marker) of Corydalis saxicola Bunting were predicted and analyzed based on the concept of quality marker, providing scientific basis for the establishment of quality evaluation system of Corydalis saxicola Bunting and reference for the development of its medicinal value.

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岩黄连(Corydalis saxicola Bunting)主要分布于广西、贵州、云南等地,为广西民间道地药材。岩黄连主要含有生物碱、黄酮、甾体类等化学成分,具有护肝、抗肿瘤、抗氧化等药理作用,常用于治疗疮疖肿毒、肝炎、肝硬化、肝癌等疾病。本文对岩黄连的化学成分和药理作用进行归纳总结,并基于质量标志物(Q-Marker)的核心理念,对岩黄连Q-Marker进行预测分析,为岩黄连质量评价体系的建立提供科学依据及其药用价值开发提供参考。

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黄秋洁,女,硕士,副教授,主要从事民族药新制剂开发研究。联系电话:(0771)2399840,E-mail:
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曾勇珠,女,硕士研究生,主要从事药剂学研究。E-mail:

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曾勇珠,女,硕士研究生,主要从事药剂学研究。E-mail:

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曾勇珠,女,硕士研究生,主要从事药剂学研究。E-mail:

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岩黄连化学成分、药理作用、临床应用研究进展及质量标志物预测分析
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曾勇珠 1 , 钟华帅 1 , 苏晓丹 1 , 陆建媚 1 , 麦琬婷 1 , 黄秋洁 2 , 叶勇 1, 3
中国新药杂志 | 综述 2023,32(13): 1325-1335
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中国新药杂志 | 综述 2023, 32(13): 1325-1335
岩黄连化学成分、药理作用、临床应用研究进展及质量标志物预测分析
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曾勇珠1 , 钟华帅1, 苏晓丹1, 陆建媚1, 麦琬婷1, 黄秋洁2 , 叶勇1, 3
作者信息
  • 1广西医科大学药学院,南宁 530021
  • 2广西中医药大学药学院,南宁 530001
  • 3广西生物活性分子研究与评价重点实验室,南宁 530021
  • 曾勇珠,女,硕士研究生,主要从事药剂学研究。E-mail:

通讯作者:

黄秋洁,女,硕士,副教授,主要从事民族药新制剂开发研究。联系电话:(0771)2399840,E-mail:
Chemical constituents, pharmacological effects and clinical applications of Corydalis saxicola Bunting and predictive analysis on quality marker
Yong-zhu ZENG1 , Hua-shuai ZHONG1, Xiao-dan SU1, Jian-mei LU1, Wan-ting MAI1, Qiu-jie HUANG2 , Yong YE1, 3
Affiliations
  • 1College of Pharmacy, Guangxi Medical University, Nanning 530021, China
  • 2College of Pharmacy, Guangxi University of Traditional Chinese Medicine, Nanning 530001, China
  • 3Guangxi Key Laboratory of Biological Activity Analysis, Research and Evaluation, Nanning 530021, China
出版时间: 2023-07-15
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岩黄连(Corydalis saxicola Bunting)主要分布于广西、贵州、云南等地,为广西民间道地药材。岩黄连主要含有生物碱、黄酮、甾体类等化学成分,具有护肝、抗肿瘤、抗氧化等药理作用,常用于治疗疮疖肿毒、肝炎、肝硬化、肝癌等疾病。本文对岩黄连的化学成分和药理作用进行归纳总结,并基于质量标志物(Q-Marker)的核心理念,对岩黄连Q-Marker进行预测分析,为岩黄连质量评价体系的建立提供科学依据及其药用价值开发提供参考。

岩黄连  /  化学成分  /  药理作用  /  临床应用  /  质量标志物

Corydalis saxicola Bunting mainly distributes in Guangxi, Guizhou and Yunnan, etc., and it is a genuine folk medicine in Guangxi Province. The chemical composition of Corydalis saxicola Bunting mainly contains alkaloids, flavonoids, steroids and so on. It has activities of liver protection, anti-tumor, and anti-oxidation, thus often used in the treatment of sore boils, hepatitis, liver cirrhosis, and liver cancer. The chemical constituents and pharmacological effects of Corydalis saxicola Bunting are summarized in this article, and the quality markers (Q-Marker) of Corydalis saxicola Bunting were predicted and analyzed based on the concept of quality marker, providing scientific basis for the establishment of quality evaluation system of Corydalis saxicola Bunting and reference for the development of its medicinal value.

Corydalis saxicola  /  chemical compositions  /  pharmacological effects  /  clinical application  /  quality markers
曾勇珠, 钟华帅, 苏晓丹, 陆建媚, 麦琬婷, 黄秋洁, 叶勇. 岩黄连化学成分、药理作用、临床应用研究进展及质量标志物预测分析. 中国新药杂志, 2023 , 32 (13) : 1325 -1335 .
Yong-zhu ZENG, Hua-shuai ZHONG, Xiao-dan SU, Jian-mei LU, Wan-ting MAI, Qiu-jie HUANG, Yong YE. Chemical constituents, pharmacological effects and clinical applications of Corydalis saxicola Bunting and predictive analysis on quality marker[J]. Chinese Journal of New Drugs, 2023 , 32 (13) : 1325 -1335 .
  • 国家自然科学基金资助项目(81960756; 81360689)
  • 广西自然科学基金资助项目(2022GXNSFDA035063; 2018GXNSFAA050078; 2015GXNSFAA139173)
  • 广西高校中青年教师科研基础能力提升基金资助项目(2019KY0148; 2019KY0315)
2023年第32卷第13期
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  • 首发时间:2026-03-05
  • 出版时间:2023-07-15
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  • 录用日期:2022-06-04
基金
国家自然科学基金资助项目(81960756; 81360689)
广西自然科学基金资助项目(2022GXNSFDA035063; 2018GXNSFAA050078; 2015GXNSFAA139173)
广西高校中青年教师科研基础能力提升基金资助项目(2019KY0148; 2019KY0315)
作者信息
    1广西医科大学药学院,南宁 530021
    2广西中医药大学药学院,南宁 530001
    3广西生物活性分子研究与评价重点实验室,南宁 530021

通讯作者:

黄秋洁,女,硕士,副教授,主要从事民族药新制剂开发研究。联系电话:(0771)2399840,E-mail:
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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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