Article(id=1321425925091209283, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425881147495164, articleNumber=null, orderNo=null, doi=10.20251/j.cnki.1003-3734.2026.18.008, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1769443200000, acceptedDateStr=2026-01-27, onlineDate=1792982091448, onlineDateStr=2026-10-26, pubDate=1790697600000, pubDateStr=2026-09-30, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792982091448, onlineIssueDateStr=2026-10-26, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792982091448, creator=13701087609, updateTime=1792982091448, updator=13701087609, issue=Issue{id=1321425881147495164, tenantId=1146029695717560320, journalId=1235980733773295621, year='2026', volume='35', issue='18', pageStart='1905', pageEnd='2016', issueExtLink='null', onlineDate='null', pubDate='1790697600000', pubDateStr='2026-09-30', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792982080970, creator='13701087609', updateTime=1792982834300, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1321429040930599029, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425881147495164, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1321429040930599030, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425881147495164, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1956, endPage=1967, ext={EN=ArticleExt(id=1321425925242204228, articleId=1321425925091209283, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Optimization of extraction process for the modified new formulation of Compound Nanxing Zhitong Plaster based on pharmacodynamic evaluation combined with orthogonal design, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To optimize the extraction process for the modified new formulation of Compound Nanxing Zhitong Plaster.
Methods: Pharmacological effects were evaluated using adjuvant-induced arthritis rat models and acetic acid-induced writhing mouse models, while skin irritation was tested in rabbits. The differences in efficacy and skin safety between two extraction methods (FFNX-1: ethanol-water-ethanol extraction; FFNX-2: percolation+ethanol extraction) were compared. Active ingredient contents (including aconitine, eugenol, etc.) and dry extract yield were used as indicators to optimize extraction parameters through orthogonal experimental design.
Results: FFNX-2 (percolation+ethanol extraction) exhibited optimal anti-swelling, anti-inflammatory and analgesic effects, along with lower skin irritation in rabbits, establishing it as the optimal extraction process for the improved new drug formulation of Compound Nanxing Zhitong Plaster.
Conclusion: The optimized extraction parameters were as follows: Six herbs including Caryophylli Flos extracted three times (1 h each) with 4 volumes of 50% ethanol; Arisaematis Rhizoma and Aconiti Radix extracted by percolation with 70% ethanol (particle size 2~5 mm, soaked for 24 h, flow rate 1 mL·min-1·kg-1, collecting 8 volumes of effluent). The optimized extraction process effectively retains active components while reducing toxicity risks, providing a scientific basis for the modern development of Compound Nanxing Zhitong Plaster.
, authors=Feng-shou LUO
1, Zhi-qiang LI
1, Xin-yan LIN
2, Ye YANG
1, Qun SUN
1, Ying ZHOU
1, Jin-feng YU
1, Xin-peng QIN
1, Shu-mei YIN
2, Li LIN
2, Ji-feng LI
2, Wen-jun LIU
1, *, Liang CAO
1, Zhen-zhong WANG
1, Wei XIAO
1, *, authorsList=Feng-shou LUO, Zhi-qiang LI, Xin-yan LIN, Ye YANG, Qun SUN, Ying ZHOU, Jin-feng YU, Xin-peng QIN, Shu-mei YIN, Li LIN, Ji-feng LI, Wen-jun LIU, Liang CAO, Zhen-zhong WANG, Wei XIAO, authorCompany=null, correspAuthors=Wen-jun LIU, Wei XIAO, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1321425925527416901, articleId=1321425925091209283, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=基于药效学评价结合正交设计的复方南星止痛膏改良型新药提取工艺优化研究, columnId=1236330556003242277, journalTitle=中国新药杂志, columnName=实验研究, runingTitle=null, highlight=null, articleAbstract=
目的： 确定并优化复方南星止痛膏改良型新药提取工艺。
方法： 采用佐剂性关节炎（adjuvant-induced arthritis, AIA）大鼠模型、冰醋酸致小鼠疼痛模型进行药效学评价，同时对家兔皮肤刺激性进行考察，比较2种提取工艺（FFNX-1：醇提+水提+醇提；FFNX-2：渗漉+醇提）在药效和皮肤安全性方面的差异；再以活性成分（乌头碱、丁香酚等）含量及干膏得率为指标，结合正交实验优化提取参数。
结果： FFNX-2（渗漉+醇提）在抑制大鼠足趾肿胀、降低炎症因子及镇痛作用上效果最优，同时能降低家兔的皮肤刺激性，确定为复方南星止痛膏改良型新药的最佳提取工艺路线。
结论： 优化后的最佳提取工艺参数为：丁香等六味以4倍量50%乙醇提取3次（每次1 h），生天南星、生川乌以70%乙醇渗漉提取（粒径2~5 mm，浸渍24 h，流速1 mL·min-1·kg-1，收集8倍量）。优化后的提取工艺在有效保留关键药效物质的同时，显著降低了潜在毒性风险，为复方南星止痛膏的现代化开发及临床应用提供了科学依据。
, authors=罗丰收
1, 李志强
1, 林新艳
2, 杨野
1, 孙群
1, 周颖
1, 余金凤
1, 秦鑫鹏
1, 殷书梅
2, 林丽
2, 李吉峰
2, 刘文君
1, *, 曹亮
1, 王振中
1, 肖伟
1, *, authorsList=罗丰收, 李志强, 林新艳, 杨野, 孙群, 周颖, 余金凤, 秦鑫鹏, 殷书梅, 林丽, 李吉峰, 刘文君, 曹亮, 王振中, 肖伟, authorCompany=null, correspAuthors=刘文君, 肖伟, authorNote=
, correspAuthorsNote=
, copyrightStatement=null, copyrightOwner=《中国新药杂志》有限公司, extLink=null, articleAbsUrl=null, sourceXml=jmZk5CGMCNpK+DfM/5vpNw==, magXml=Bct2Y0YlAQzKJJQDBqS9eg==, pdfUrl=null, pdf=kYG1pkvwB8Lo3zlrRKHLNg==, pdfFileSize=8012410, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=N8KEcekiU5u/jlINMKMfPw==, mapNumber=null, fund=null)}, authors=[Author(id=1321425925930070093, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=wowo997@163.com, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425926018150479, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425925930070093, language=EN, stringName=Feng-shou LUO, firstName=Feng-shou, middleName=null, lastName=LUO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425926097842256, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425925930070093, language=CN, stringName=罗丰收, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112, bio={"content":"
罗丰收，男，中级工程师，主要从事中药新药研究。E-mail: wowo997@163.com。
"}, bioImg=null, bioContent=
罗丰收，男，中级工程师，主要从事中药新药研究。E-mail: wowo997@163.com。
, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925711966278, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=1, ext=[AuthorCompanyExt(id=1321425925728743495, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China), AuthorCompanyExt(id=1321425925741326408, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112)])]), Author(id=1321425926206894162, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425926315946068, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425926206894162, language=EN, stringName=Zhi-qiang LI, firstName=Zhi-qiang, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425926378860629, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425926206894162, language=CN, stringName=李志强, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925711966278, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=1, ext=[AuthorCompanyExt(id=1321425925728743495, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China), AuthorCompanyExt(id=1321425925741326408, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112)])]), Author(id=1321425926450163799, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425926521466969, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425926450163799, language=EN, stringName=Xin-yan LIN, firstName=Xin-yan, middleName=null, lastName=LIN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, address=
2Jiangsu Kangyuan Sunshine Pharmaceutical Co., Ltd., Nanjing 210046, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425926592770138, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425926450163799, language=CN, stringName=林新艳, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, address=
2江苏康缘阳光药业有限公司，南京 210046, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925825212489, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=2, ext=[AuthorCompanyExt(id=1321425925837795402, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925825212489, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2Jiangsu Kangyuan Sunshine Pharmaceutical Co., Ltd., Nanjing 210046, China), AuthorCompanyExt(id=1321425925846184011, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925825212489, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2江苏康缘阳光药业有限公司，南京 210046)])]), Author(id=1321425926655684700, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425926714404958, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425926655684700, language=EN, stringName=Ye YANG, firstName=Ye, middleName=null, lastName=YANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425926781513823, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425926655684700, language=CN, stringName=杨野, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925711966278, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=1, ext=[AuthorCompanyExt(id=1321425925728743495, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China), AuthorCompanyExt(id=1321425925741326408, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112)])]), Author(id=1321425926848622689, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425926949285987, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425926848622689, language=EN, stringName=Qun SUN, firstName=Qun, middleName=null, lastName=SUN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425927028977764, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425926848622689, language=CN, stringName=孙群, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925711966278, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=1, ext=[AuthorCompanyExt(id=1321425925728743495, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China), AuthorCompanyExt(id=1321425925741326408, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112)])]), Author(id=1321425927100280934, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425928744448104, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425927100280934, language=EN, stringName=Ying ZHOU, firstName=Ying, middleName=null, lastName=ZHOU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425928815751273, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425927100280934, language=CN, stringName=周颖, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925711966278, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=1, ext=[AuthorCompanyExt(id=1321425925728743495, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China), AuthorCompanyExt(id=1321425925741326408, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112)])]), Author(id=1321425928882860139, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=6, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425928958357613, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425928882860139, language=EN, stringName=Jin-feng YU, firstName=Jin-feng, middleName=null, lastName=YU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425929033855086, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425928882860139, language=CN, stringName=余金凤, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925711966278, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=1, ext=[AuthorCompanyExt(id=1321425925728743495, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China), AuthorCompanyExt(id=1321425925741326408, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112)])]), Author(id=1321425929100963952, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=7, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425929193238642, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425929100963952, language=EN, stringName=Xin-peng QIN, firstName=Xin-peng, middleName=null, lastName=QIN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425929268736115, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425929100963952, language=CN, stringName=秦鑫鹏, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925711966278, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=1, ext=[AuthorCompanyExt(id=1321425925728743495, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China), AuthorCompanyExt(id=1321425925741326408, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112)])]), Author(id=1321425929327456373, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=8, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425929398759543, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425929327456373, language=EN, stringName=Shu-mei YIN, firstName=Shu-mei, middleName=null, lastName=YIN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, address=
2Jiangsu Kangyuan Sunshine Pharmaceutical Co., Ltd., Nanjing 210046, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425929470062712, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425929327456373, language=CN, stringName=殷书梅, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, address=
2江苏康缘阳光药业有限公司，南京 210046, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925825212489, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=2, ext=[AuthorCompanyExt(id=1321425925837795402, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925825212489, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2Jiangsu Kangyuan Sunshine Pharmaceutical Co., Ltd., Nanjing 210046, China), AuthorCompanyExt(id=1321425925846184011, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925825212489, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2江苏康缘阳光药业有限公司，南京 210046)])]), Author(id=1321425929528782970, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=9, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425929608474748, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425929528782970, language=EN, stringName=Li LIN, firstName=Li, middleName=null, lastName=LIN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, address=
2Jiangsu Kangyuan Sunshine Pharmaceutical Co., Ltd., Nanjing 210046, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425929667195005, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425929528782970, language=CN, stringName=林丽, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, address=
2江苏康缘阳光药业有限公司，南京 210046, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925825212489, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=2, ext=[AuthorCompanyExt(id=1321425925837795402, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925825212489, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2Jiangsu Kangyuan Sunshine Pharmaceutical Co., Ltd., Nanjing 210046, China), AuthorCompanyExt(id=1321425925846184011, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925825212489, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2江苏康缘阳光药业有限公司，南京 210046)])]), Author(id=1321425929734303871, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=10, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425929797218433, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425929734303871, language=EN, stringName=Ji-feng LI, firstName=Ji-feng, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, address=
2Jiangsu Kangyuan Sunshine Pharmaceutical Co., Ltd., Nanjing 210046, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425929860132994, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425929734303871, language=CN, stringName=李吉峰, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, address=
2江苏康缘阳光药业有限公司，南京 210046, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925825212489, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=2, ext=[AuthorCompanyExt(id=1321425925837795402, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925825212489, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2Jiangsu Kangyuan Sunshine Pharmaceutical Co., Ltd., Nanjing 210046, China), AuthorCompanyExt(id=1321425925846184011, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925825212489, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2江苏康缘阳光药业有限公司，南京 210046)])]), Author(id=1321425929935630468, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=11, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=lwj.518@163.com, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1321425930023710854, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425929935630468, language=EN, stringName=Wen-jun LIU, firstName=Wen-jun, middleName=null, lastName=LIU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, *, address=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425930090819719, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425929935630468, language=CN, stringName=刘文君, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, *, address=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925711966278, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=1, ext=[AuthorCompanyExt(id=1321425925728743495, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China), AuthorCompanyExt(id=1321425925741326408, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112)])]), Author(id=1321425930149539977, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=12, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425930262786187, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425930149539977, language=EN, stringName=Liang CAO, firstName=Liang, middleName=null, lastName=CAO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425930355060876, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425930149539977, language=CN, stringName=曹亮, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925711966278, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=1, ext=[AuthorCompanyExt(id=1321425925728743495, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China), AuthorCompanyExt(id=1321425925741326408, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112)])]), Author(id=1321425930422169742, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=13, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425930497667216, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425930422169742, language=EN, stringName=Zhen-zhong WANG, firstName=Zhen-zhong, middleName=null, lastName=WANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425930552193169, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425930422169742, language=CN, stringName=王振中, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925711966278, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=1, ext=[AuthorCompanyExt(id=1321425925728743495, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China), AuthorCompanyExt(id=1321425925741326408, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112)])]), Author(id=1321425930623496339, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, orderNo=14, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=kanionlunwen@163.com, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1321425930694799509, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425930623496339, language=EN, stringName=Wei XIAO, firstName=Wei, middleName=null, lastName=XIAO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, *, address=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425930766102678, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, authorId=1321425930623496339, language=CN, stringName=肖伟, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, *, address=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425925711966278, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=1, ext=[AuthorCompanyExt(id=1321425925728743495, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China), AuthorCompanyExt(id=1321425925741326408, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112)])])], keywords=[Keyword(id=1321425930866765975, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=EN, orderNo=1, keyword=Compound Nanxing Zhitong Plaster), Keyword(id=1321425930933874840, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=EN, orderNo=2, keyword=improved new formulation), Keyword(id=1321425931013566617, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=EN, orderNo=3, keyword=pharmacodynamics), Keyword(id=1321425931084869786, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=EN, orderNo=4, keyword=orthogonal design), Keyword(id=1321425931193921691, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=EN, orderNo=5, keyword=extraction technology), Keyword(id=1321425931261030556, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=EN, orderNo=6, keyword=aconitine), Keyword(id=1321425931323945117, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=EN, orderNo=7, keyword=eugenol), Keyword(id=1321425931382665374, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=CN, orderNo=1, keyword=复方南星止痛膏), Keyword(id=1321425931466551455, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=CN, orderNo=2, keyword=改良型新药), Keyword(id=1321425931533660320, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=CN, orderNo=3, keyword=药效学), Keyword(id=1321425933194604705, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=CN, orderNo=4, keyword=正交设计), Keyword(id=1321425933261713570, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=CN, orderNo=5, keyword=提取工艺), Keyword(id=1321425933316239523, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=CN, orderNo=6, keyword=乌头碱), Keyword(id=1321425933374959780, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, language=CN, orderNo=7, keyword=丁香酚)], refs=null, funds=[Fund(id=1321425933463040165, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, awardId=BK20232014, language=CN, fundingSource=江苏省基础研究计划自然科学基金资助项目：前沿引领技术基础研究专项(BK20232014), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1321425925711966278, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=1, ext=[AuthorCompanyExt(id=1321425925728743495, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1State Key Laboratory of Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture (Jiangsu Kanion Pharmaceutical Co., Ltd.), Nanjing 211112, China), AuthorCompanyExt(id=1321425925741326408, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925711966278, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1中药制药过程控制与智能制造技术全国重点实验室（江苏康缘药业股份有限公司），南京 211112)]), AuthorCompany(id=1321425925825212489, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, xref=2, ext=[AuthorCompanyExt(id=1321425925837795402, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925825212489, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2Jiangsu Kangyuan Sunshine Pharmaceutical Co., Ltd., Nanjing 210046, China), AuthorCompanyExt(id=1321425925846184011, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425925091209283, companyId=1321425925825212489, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2江苏康缘阳光药业有限公司，南京 210046)])], figs=null, attaches=null, journal=Journal(id=1235980159023624194, delFlag=0, nameCn=中国新药杂志, nameEn=Chinese Journal of New Drugs, nameHistory1=null, nameHistory2=null, issn=1003-3734, eissn=null, cn=11-2850/R, coden=ZXZHA6, periodic=3, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=ohPEEN//Vz1tDT3ZBNTp4Q==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Journal of New Drugs, journalRemark=null, publicationField=null, createdTime=1772610233314, updatedTime=1788948968376, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=ohPEEN//Vz1tDT3ZBNTp4Q==, picEn=f9WK9bvTM4guTmS/iGhOMg==, jcr=null, cjcr=null, exts=[JournalExt(id=1304509780974924039, language=CN, name=中国新药杂志, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788948968404, updatedTime=1788948968404, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=http://draft.newdrug.cn/journalx_zgxy/authorLogOn.action, submissionEditorUrl=http://draft.newdrug.cn/journalx_zgxy/editorLogOn.action, submissionReviewUrl=http://draft.newdrug.cn/journalx_zgxy/expertLogOn.action, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1304509781025255688, language=EN, name=Chinese Journal of New Drugs, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788948968416, updatedTime=1788948968416, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=http://draft.newdrug.cn/journalx_zgxy/authorLogOn.action, submissionEditorUrl=http://draft.newdrug.cn/journalx_zgxy/editorLogOn.action, submissionReviewUrl=http://draft.newdrug.cn/journalx_zgxy/expertLogOn.action, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1235980733773295621, websiteList=[Website(id=1235982099191222761, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1235980733773295621, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zgxyzz/CN, language=CN, createTime=1772610695884, createBy=18614031015, updateTime=1772610860397, updateBy=18614031015, name=中国新药杂志-中文, tplId=1146099689490845704, title=中国新药杂志, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1235983918629966444, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=articleTextType, value=kx, createTime=1772611129672, updateTime=1772611129672, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918604800617, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=banner, value=null, createTime=1772611129666, updateTime=1772611129666, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918655132271, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=grayFlag, value=0, createTime=1772611129678, updateTime=1772611129678, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918596412008, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=logo, value=https://castjournals.cast.org.cn/joweb/zgxyzz/CN/file/pic?fileId=W567vm71kFC7UhK9TSU6xw==, createTime=1772611129664, updateTime=1772611129664, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918667715185, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=minRunFlag, value=0, createTime=1772611129681, updateTime=1772611129681, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918617383531, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zgxyzz/CN/file/pic, createTime=1772611129669, updateTime=1772611129669, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918659326576, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=silenceFlag, value=0, createTime=1772611129679, updateTime=1772611129679, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918613189226, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1772611129668, updateTime=1772611129668, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918634160749, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=themeColor, value=null, createTime=1772611129673, updateTime=1772611129673, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918646743662, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=themeStyle, value=null, createTime=1772611129676, updateTime=1772611129676, creator=18614031015, updator=18614031015)]), Website(id=1235982099270914542, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1235980733773295621, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zgxyzz/EN, language=EN, createTime=1772610695903, createBy=18614031015, updateTime=1772610875891, updateBy=18614031015, name=中国新药杂志-英文, tplId=1146101810881728533, title=Chinese Journal of New Drugs, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1235983955829248630, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=articleTextType, value=kx, createTime=1772611138541, updateTime=1772611138541, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955804082803, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=banner, value=null, createTime=1772611138535, updateTime=1772611138535, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955854414457, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=grayFlag, value=0, createTime=1772611138547, updateTime=1772611138547, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955795694194, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=logo, value=https://castjournals.cast.org.cn/joweb/zgxyzz/EN/file/pic?fileId=W567vm71kFC7UhK9TSU6xw==, createTime=1772611138533, updateTime=1772611138533, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955866997371, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=minRunFlag, value=0, createTime=1772611138550, updateTime=1772611138550, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955820860021, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zgxyzz/EN/file/pic, createTime=1772611138539, updateTime=1772611138539, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955862803066, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=silenceFlag, value=0, createTime=1772611138549, updateTime=1772611138549, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955812471412, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1772611138537, updateTime=1772611138537, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955837637239, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=themeColor, value=null, createTime=1772611138543, updateTime=1772611138543, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955846025848, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=themeStyle, value=null, createTime=1772611138545, updateTime=1772611138545, creator=18614031015, updator=18614031015)])], journalTitle=中国新药杂志, weixinUrl=null, journalUrl=http://www.newdrug.cn/, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Journal of New Drugs, journalPhotoCn=ohPEEN//Vz1tDT3ZBNTp4Q==, journalPhotoEn=f9WK9bvTM4guTmS/iGhOMg==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zgxyzz/CN/10.20251/j.cnki.1003-3734.2026.18.008, detailUrlEn=https://castjournals.cast.org.cn/joweb/zgxyzz/EN/10.20251/j.cnki.1003-3734.2026.18.008, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zgxyzz/CN/PDF/10.20251/j.cnki.1003-3734.2026.18.008, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zgxyzz/EN/PDF/10.20251/j.cnki.1003-3734.2026.18.008, aliStartDate=0, aliEndDate=0, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1790697600000, fullTextJson=null, articleText=null, reference=null)
PDF下载
全屏
31
6
关闭全屏
北京市海淀区学院南路86号
010-62662699（运营及技术支持）
qkjq@cast.org.cn
