Article(id=1321425902861398898, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425847911830056, articleNumber=null, orderNo=null, doi=10.20251/j.cnki.1003-3734.2026.17.011, pmid=null, cstr=null, oa=null, hot=null, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=null, receivedDateStr=null, revisedDate=null, revisedDateStr=null, acceptedDate=1773849600000, acceptedDateStr=2026-03-19, onlineDate=1792982086147, onlineDateStr=2026-10-26, pubDate=1789401600000, pubDateStr=2026-09-15, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1792982086147, onlineIssueDateStr=2026-10-26, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1792982086147, creator=13701087609, updateTime=1792982086147, updator=13701087609, issue=Issue{id=1321425847911830056, tenantId=1146029695717560320, journalId=1235980733773295621, year='2026', volume='35', issue='17', pageStart='1793', pageEnd='1904', issueExtLink='null', onlineDate='null', pubDate='1789401600000', pubDateStr='2026-09-15', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1792982073047, creator='13701087609', updateTime=1792982858328, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1321429141673586821, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425847911830056, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1321429141673586822, tenantId=1146029695717560320, journalId=1235980733773295621, issueId=1321425847911830056, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1866, endPage=1876, ext={EN=ArticleExt(id=1321425903066919795, articleId=1321425902861398898, tenantId=1146029695717560320, journalId=1235980733773295621, language=EN, title=Investigation of extraction processes for paediatric appetite-enhancing gels and optimisation of formulation techniques, columnId=null, journalTitle=Chinese Journal of New Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=
Objective: To optimize the extraction and formulation processes for paediatric appetite-enhancing Gel (PAG).
Methods: The content of forsythoside, dry extract yield, and total flavonoid content in PAG were used as evaluation indicators. The analytic hierarchy process (AHP) combined with the criteria importance through intercriteria correlation (CRITIC) method was employed to calculate the comprehensive weighting coefficients for each indicator. The factors considered were water-to-raw-material ratio, extraction time, and extraction number. A multi-indicator comprehensive scoring method combined with the Box-Behnken design-response surface methodology (BBD-RSM) was used to design the experiment, aiming to determine the optimal water extraction process for PAG. The formulation process of PAG was optimized based on evaluation criteria including appearance and adhesiveness.
Results: The optimal process for PAG was determined to be a water-to-raw-material ratio of 10-fold, extraction for 1.5 h, and three extraction cycles. Validation experiments confirmed that the extraction process for PAG is stable and feasible. The optimal formulation process for PAG was determined to be: carrageenan∶barley β-glucan∶sucrose∶water (2 g∶1 g∶1 g∶30 mL).
Conclusion: Based on the quality-by-design principle, the extraction process for PAG was optimized through a combined approach of multi-criteria evaluation and the Box-Behnken response surface methodology. Subsequently, the formulation process for the gel was refined using evaluation criteria such as appearance and adhesiveness. This study provides reference data for the modern extraction research on this formulation and for the development of pediatric preparations.
, authors=Wen-rong LIU
1, Ying-mei LI
1, Shui-xiang WANG
1, Cheng-song LIU
2, 3, Peng-xiang GUO
2, 3, Zi-ming JIN
2, 3, Xia DOU
2, 3, *, authorsList=Wen-rong LIU, Ying-mei LI, Shui-xiang WANG, Cheng-song LIU, Peng-xiang GUO, Zi-ming JIN, Xia DOU, authorCompany=null, correspAuthors=Xia DOU, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1321425903381492596, articleId=1321425902861398898, tenantId=1146029695717560320, journalId=1235980733773295621, language=CN, title=小儿开胃增食凝胶提取工艺考察及成型工艺优选, columnId=1236330556003242277, journalTitle=中国新药杂志, columnName=实验研究, runingTitle=null, highlight=null, articleAbstract=
目的： 优选小儿开胃增食凝胶的提取工艺及成型工艺。
方法： 以连翘苷含量、干膏率及总黄酮含量作为考察指标，采用层次分析法（analytic hierarchy process, AHP）结合CRITIC（criteria importance through intercriteria correlation）法计算各指标的综合权重系数，以加水倍数、提取时间和提取次数为考察因素，以多指标综合评分与Box-Behnken设计-响应面法结合设计实验，考察小儿开胃增食凝胶的最佳水提工艺。以外观性状、黏附力等评价标准优选小儿开胃增食凝胶的成型工艺。
结果： 优选出小儿开胃增食凝胶的最佳提取工艺为加10倍量水、提取时间为1.5 h、提取次数为3次，并通过验证实验确定了小儿开胃增食凝胶的提取工艺稳定可行。筛选出小儿开胃增食凝胶的最佳成型工艺为卡拉胶∶青稞β-葡聚糖∶蔗糖∶水（2 g∶1 g∶1 g∶30 mL）。
结论： 基于质量源于设计理念，采用多指标综合评分与Box-Behnken响应面法结合优选得到小儿开胃增食凝胶提取工艺，再以外观性状、黏附力等评价标准优选小儿开胃增食凝胶的成型工艺，可为该方剂的现代提取研究及儿童复方制剂的剂型开发提供一定的数据参考。
, authors=刘文蓉
1, 李英梅
1, 王水香
1, 刘成松
2, 3, 郭鹏翔
2, 3, 靳子明
2, 3, 窦霞
2, 3, *, authorsList=刘文蓉, 李英梅, 王水香, 刘成松, 郭鹏翔, 靳子明, 窦霞, authorCompany=null, correspAuthors=窦霞, authorNote=
, correspAuthorsNote=
, copyrightStatement=null, copyrightOwner=《中国新药杂志》有限公司, extLink=null, articleAbsUrl=null, sourceXml=3J2c7JrgBok8So8Nd9/n/g==, magXml=2GOGpDnOSicAv11GEsN8xQ==, pdfUrl=null, pdf=Bc+zxrDI2XqRgs890QMTSg==, pdfFileSize=5606536, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=uyzCfwsn097MGZwLHDID2A==, mapNumber=null, fund=null)}, authors=[Author(id=1321425903842866047, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, orderNo=0, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=19896005949@163.com, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425903926752129, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425903842866047, language=EN, stringName=Wen-rong LIU, firstName=Wen-rong, middleName=null, lastName=LIU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425904002249602, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425903842866047, language=CN, stringName=刘文蓉, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1甘肃中医药大学药学院，兰州 730000, bio={"content":"
刘文蓉，女，硕士研究生，研究方向：中药炮制与中药制药工艺。E-mail: 19896005949@163.com。
"}, bioImg=null, bioContent=
刘文蓉，女，硕士研究生，研究方向：中药炮制与中药制药工艺。E-mail: 19896005949@163.com。
, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425903587013493, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=1, ext=[AuthorCompanyExt(id=1321425903599596406, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903587013493, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China), AuthorCompanyExt(id=1321425903607985015, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903587013493, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1甘肃中医药大学药学院，兰州 730000)])]), Author(id=1321425904077747076, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, orderNo=1, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425904149050246, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425904077747076, language=EN, stringName=Ying-mei LI, firstName=Ying-mei, middleName=null, lastName=LI, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425904216159111, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425904077747076, language=CN, stringName=李英梅, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1甘肃中医药大学药学院，兰州 730000, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425903587013493, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=1, ext=[AuthorCompanyExt(id=1321425903599596406, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903587013493, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China), AuthorCompanyExt(id=1321425903607985015, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903587013493, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1甘肃中医药大学药学院，兰州 730000)])]), Author(id=1321425904287462281, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, orderNo=2, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425904358765451, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425904287462281, language=EN, stringName=Shui-xiang WANG, firstName=Shui-xiang, middleName=null, lastName=WANG, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425904417485708, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425904287462281, language=CN, stringName=王水香, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
1, address=
1甘肃中医药大学药学院，兰州 730000, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425903587013493, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=1, ext=[AuthorCompanyExt(id=1321425903599596406, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903587013493, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China), AuthorCompanyExt(id=1321425903607985015, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903587013493, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1甘肃中医药大学药学院，兰州 730000)])]), Author(id=1321425904484594574, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, orderNo=3, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425904547509137, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425904484594574, language=EN, stringName=Cheng-song LIU, firstName=Cheng-song, middleName=null, lastName=LIU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, 3, address=
2Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730020, China
3Jin Ziming National Traditional Medicine Practitioner Inheritance Studio, Lanzhou 730020, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425904623006610, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425904484594574, language=CN, stringName=刘成松, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, 3, address=
2甘肃中医药大学附属医院，兰州 730020
3靳子明全国老药工传承工作室，兰州 730020, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425903683482488, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=2, ext=[AuthorCompanyExt(id=1321425903691871097, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903683482488, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730020, China), AuthorCompanyExt(id=1321425903700259706, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903683482488, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2甘肃中医药大学附属医院，兰州 730020)]), AuthorCompany(id=1321425903763174267, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=3, ext=[AuthorCompanyExt(id=1321425903775757180, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903763174267, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3Jin Ziming National Traditional Medicine Practitioner Inheritance Studio, Lanzhou 730020, China), AuthorCompanyExt(id=1321425903779951485, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903763174267, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3靳子明全国老药工传承工作室，兰州 730020)])]), Author(id=1321425906321699732, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, orderNo=4, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425906405585815, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425906321699732, language=EN, stringName=Peng-xiang GUO, firstName=Peng-xiang, middleName=null, lastName=GUO, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, 3, address=
2Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730020, China
3Jin Ziming National Traditional Medicine Practitioner Inheritance Studio, Lanzhou 730020, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425906468500376, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425906321699732, language=CN, stringName=郭鹏翔, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, 3, address=
2甘肃中医药大学附属医院，兰州 730020
3靳子明全国老药工传承工作室，兰州 730020, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425903683482488, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=2, ext=[AuthorCompanyExt(id=1321425903691871097, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903683482488, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730020, China), AuthorCompanyExt(id=1321425903700259706, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903683482488, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2甘肃中医药大学附属医院，兰州 730020)]), AuthorCompany(id=1321425903763174267, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=3, ext=[AuthorCompanyExt(id=1321425903775757180, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903763174267, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3Jin Ziming National Traditional Medicine Practitioner Inheritance Studio, Lanzhou 730020, China), AuthorCompanyExt(id=1321425903779951485, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903763174267, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3靳子明全国老药工传承工作室，兰州 730020)])]), Author(id=1321425906535609242, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, orderNo=5, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=null, emailSecond=null, emailThird=null, correspondingAuthor=0, authorType=1, ext={EN=AuthorExt(id=1321425906611106717, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425906535609242, language=EN, stringName=Zi-ming JIN, firstName=Zi-ming, middleName=null, lastName=JIN, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, 3, address=
2Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730020, China
3Jin Ziming National Traditional Medicine Practitioner Inheritance Studio, Lanzhou 730020, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425906669826974, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425906535609242, language=CN, stringName=靳子明, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, 3, address=
2甘肃中医药大学附属医院，兰州 730020
3靳子明全国老药工传承工作室，兰州 730020, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425903683482488, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=2, ext=[AuthorCompanyExt(id=1321425903691871097, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903683482488, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730020, China), AuthorCompanyExt(id=1321425903700259706, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903683482488, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2甘肃中医药大学附属医院，兰州 730020)]), AuthorCompany(id=1321425903763174267, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=3, ext=[AuthorCompanyExt(id=1321425903775757180, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903763174267, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3Jin Ziming National Traditional Medicine Practitioner Inheritance Studio, Lanzhou 730020, China), AuthorCompanyExt(id=1321425903779951485, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903763174267, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3靳子明全国老药工传承工作室，兰州 730020)])]), Author(id=1321425906732741536, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, orderNo=6, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=0, email=doux125@126.com, emailSecond=null, emailThird=null, correspondingAuthor=1, authorType=1, ext={EN=AuthorExt(id=1321425906812433315, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425906732741536, language=EN, stringName=Xia DOU, firstName=Xia, middleName=null, lastName=DOU, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, 3, *, address=
2Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730020, China
3Jin Ziming National Traditional Medicine Practitioner Inheritance Studio, Lanzhou 730020, China, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=1321425906896319396, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, authorId=1321425906732741536, language=CN, stringName=窦霞, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=
2, 3, *, address=
2甘肃中医药大学附属医院，兰州 730020
3靳子明全国老药工传承工作室，兰州 730020, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=[AuthorCompany(id=1321425903683482488, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=2, ext=[AuthorCompanyExt(id=1321425903691871097, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903683482488, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730020, China), AuthorCompanyExt(id=1321425903700259706, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903683482488, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2甘肃中医药大学附属医院，兰州 730020)]), AuthorCompany(id=1321425903763174267, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=3, ext=[AuthorCompanyExt(id=1321425903775757180, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903763174267, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3Jin Ziming National Traditional Medicine Practitioner Inheritance Studio, Lanzhou 730020, China), AuthorCompanyExt(id=1321425903779951485, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903763174267, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3靳子明全国老药工传承工作室，兰州 730020)])])], keywords=[Keyword(id=1321425906992788389, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, language=EN, orderNo=1, keyword=paediatric appetite-enhancing gel), Keyword(id=1321425907055702950, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, language=EN, orderNo=2, keyword=extraction process optimization), Keyword(id=1321425907152171943, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, language=EN, orderNo=3, keyword=AHP-CRITIC hybrid weighting method), Keyword(id=1321425907223475112, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, language=EN, orderNo=4, keyword=Box-Behnken design-response surface methodology), Keyword(id=1321425907286389673, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, language=EN, orderNo=5, keyword=optimal selection of molding process), Keyword(id=1321425907340915626, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, language=CN, orderNo=1, keyword=小儿开胃增食凝胶), Keyword(id=1321425907408024491, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, language=CN, orderNo=2, keyword=提取工艺优化), Keyword(id=1321425907466744748, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, language=CN, orderNo=3, keyword=AHP-CRITIC混合加权法), Keyword(id=1321425907529659309, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, language=CN, orderNo=4, keyword=Box-Behnken设计-响应面法), Keyword(id=1321425907609351086, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, language=CN, orderNo=5, keyword=成型工艺优选)], refs=null, funds=[Fund(id=1321425907705820079, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, awardId=82360944, language=CN, fundingSource=国家自然科学基金资助项目(82360944), fundOrder=null, country=null), Fund(id=1321425907764540336, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, awardId=25JRRA239, language=CN, fundingSource=甘肃省自然科学基金资助项目(25JRRA239), fundOrder=null, country=null), Fund(id=1321425907827454897, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, awardId=2025GSMPA056, language=CN, fundingSource=甘肃省2025年药品监管科学研究项目(2025GSMPA056), fundOrder=null, country=null), Fund(id=1321425907902952370, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, awardId=GZKZ-2025-34, language=CN, fundingSource=甘肃省中医药科研课题(GZKZ-2025-34), fundOrder=null, country=null), Fund(id=1321425907982644147, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, awardId=2023GSMPA027, language=CN, fundingSource=甘肃省2023年度药品监管科学研究项目(2023GSMPA027), fundOrder=null, country=null)], companyList=[AuthorCompany(id=1321425903587013493, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=1, ext=[AuthorCompanyExt(id=1321425903599596406, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903587013493, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China), AuthorCompanyExt(id=1321425903607985015, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903587013493, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
1甘肃中医药大学药学院，兰州 730000)]), AuthorCompany(id=1321425903683482488, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=2, ext=[AuthorCompanyExt(id=1321425903691871097, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903683482488, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730020, China), AuthorCompanyExt(id=1321425903700259706, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903683482488, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
2甘肃中医药大学附属医院，兰州 730020)]), AuthorCompany(id=1321425903763174267, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, xref=3, ext=[AuthorCompanyExt(id=1321425903775757180, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903763174267, language=EN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3Jin Ziming National Traditional Medicine Practitioner Inheritance Studio, Lanzhou 730020, China), AuthorCompanyExt(id=1321425903779951485, tenantId=1146029695717560320, journalId=1235980733773295621, articleId=1321425902861398898, companyId=1321425903763174267, language=CN, country=null, province=null, city=null, postcode=null, companyName=null, departmentName=null, remark=
3靳子明全国老药工传承工作室，兰州 730020)])], figs=null, attaches=null, journal=Journal(id=1235980159023624194, delFlag=0, nameCn=中国新药杂志, nameEn=Chinese Journal of New Drugs, nameHistory1=null, nameHistory2=null, issn=1003-3734, eissn=null, cn=11-2850/R, coden=ZXZHA6, periodic=3, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=ohPEEN//Vz1tDT3ZBNTp4Q==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Journal of New Drugs, journalRemark=null, publicationField=null, createdTime=1772610233314, updatedTime=1788948968376, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=ohPEEN//Vz1tDT3ZBNTp4Q==, picEn=f9WK9bvTM4guTmS/iGhOMg==, jcr=null, cjcr=null, exts=[JournalExt(id=1304509780974924039, language=CN, name=中国新药杂志, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788948968404, updatedTime=1788948968404, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=http://draft.newdrug.cn/journalx_zgxy/authorLogOn.action, submissionEditorUrl=http://draft.newdrug.cn/journalx_zgxy/editorLogOn.action, submissionReviewUrl=http://draft.newdrug.cn/journalx_zgxy/expertLogOn.action, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1304509781025255688, language=EN, name=Chinese Journal of New Drugs, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788948968416, updatedTime=1788948968416, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=http://draft.newdrug.cn/journalx_zgxy/authorLogOn.action, submissionEditorUrl=http://draft.newdrug.cn/journalx_zgxy/editorLogOn.action, submissionReviewUrl=http://draft.newdrug.cn/journalx_zgxy/expertLogOn.action, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1235980733773295621, websiteList=[Website(id=1235982099191222761, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1235980733773295621, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zgxyzz/CN, language=CN, createTime=1772610695884, createBy=18614031015, updateTime=1772610860397, updateBy=18614031015, name=中国新药杂志-中文, tplId=1146099689490845704, title=中国新药杂志, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1235983918629966444, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=articleTextType, value=kx, createTime=1772611129672, updateTime=1772611129672, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918604800617, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=banner, value=null, createTime=1772611129666, updateTime=1772611129666, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918655132271, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=grayFlag, value=0, createTime=1772611129678, updateTime=1772611129678, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918596412008, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=logo, value=https://castjournals.cast.org.cn/joweb/zgxyzz/CN/file/pic?fileId=W567vm71kFC7UhK9TSU6xw==, createTime=1772611129664, updateTime=1772611129664, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918667715185, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=minRunFlag, value=0, createTime=1772611129681, updateTime=1772611129681, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918617383531, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zgxyzz/CN/file/pic, createTime=1772611129669, updateTime=1772611129669, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918659326576, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=silenceFlag, value=0, createTime=1772611129679, updateTime=1772611129679, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918613189226, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1772611129668, updateTime=1772611129668, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918634160749, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=themeColor, value=null, createTime=1772611129673, updateTime=1772611129673, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983918646743662, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099191222761, code=themeStyle, value=null, createTime=1772611129676, updateTime=1772611129676, creator=18614031015, updator=18614031015)]), Website(id=1235982099270914542, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1235980733773295621, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zgxyzz/EN, language=EN, createTime=1772610695903, createBy=18614031015, updateTime=1772610875891, updateBy=18614031015, name=中国新药杂志-英文, tplId=1146101810881728533, title=Chinese Journal of New Drugs, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1235983955829248630, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=articleTextType, value=kx, createTime=1772611138541, updateTime=1772611138541, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955804082803, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=banner, value=null, createTime=1772611138535, updateTime=1772611138535, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955854414457, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=grayFlag, value=0, createTime=1772611138547, updateTime=1772611138547, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955795694194, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=logo, value=https://castjournals.cast.org.cn/joweb/zgxyzz/EN/file/pic?fileId=W567vm71kFC7UhK9TSU6xw==, createTime=1772611138533, updateTime=1772611138533, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955866997371, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=minRunFlag, value=0, createTime=1772611138550, updateTime=1772611138550, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955820860021, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zgxyzz/EN/file/pic, createTime=1772611138539, updateTime=1772611138539, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955862803066, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=silenceFlag, value=0, createTime=1772611138549, updateTime=1772611138549, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955812471412, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1772611138537, updateTime=1772611138537, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955837637239, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=themeColor, value=null, createTime=1772611138543, updateTime=1772611138543, creator=18614031015, updator=18614031015), WebsiteProps(id=1235983955846025848, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1235982099270914542, code=themeStyle, value=null, createTime=1772611138545, updateTime=1772611138545, creator=18614031015, updator=18614031015)])], journalTitle=中国新药杂志, weixinUrl=null, journalUrl=http://www.newdrug.cn/, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Journal of New Drugs, journalPhotoCn=ohPEEN//Vz1tDT3ZBNTp4Q==, journalPhotoEn=f9WK9bvTM4guTmS/iGhOMg==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zgxyzz/CN/10.20251/j.cnki.1003-3734.2026.17.011, detailUrlEn=https://castjournals.cast.org.cn/joweb/zgxyzz/EN/10.20251/j.cnki.1003-3734.2026.17.011, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zgxyzz/CN/PDF/10.20251/j.cnki.1003-3734.2026.17.011, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zgxyzz/EN/PDF/10.20251/j.cnki.1003-3734.2026.17.011, aliStartDate=0, aliEndDate=0, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1789401600000, fullTextJson=null, articleText=null, reference=null)
PDF下载
全屏
38
6
关闭全屏
北京市海淀区学院南路86号
010-62662699（运营及技术支持）
qkjq@cast.org.cn
