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journalTitle=中草药, columnName=综述, runingTitle=null, highlight=null, articleAbstract=乳香是我国传统常用中药,具有活血止痛、消肿生肌等功效,临床应用历史悠久。从乳香中已分离鉴定出400余种化合物,其中二萜类和三萜类化合物为其主要活性成分。乳香及其活性成分具有抗炎、护肝、抗肿瘤等药理作用,其作用机制涉及抑制炎症介质释放、调控氧化应激等多个层面。综述了近几年乳香化学成分及药理作用的研究进展,以期为乳香的进一步开发利用及相关基础与临床研究提供参考。, authors=佘一鸣1, authorsList=佘一鸣, authorCompany=1 天津市北辰医院, 天津 300400, correspAuthors=null, authorNote=佘一鸣: 佘一鸣,女,硕士,研究方向为中药。E-mail:ysg6767@163.com, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=HFd8S0h1UCjdVKRvJSOfjw==, pdfFileSize=790810, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null)}, authors=null, keywords=[Keyword(id=1322634690406761232, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1322631293834220107, 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Gnedy M M A, Hussien R A A, Sleem R A, et al. In vitro efficacy of Boswellia carterii resin extracts formulated as an emulsifiable concentrate against Tetranychus urticae and phytopathogenic fungi [J]. Saudi J Biol Sci, 2023, 30(12): 103843.
Hasson S O, Jasim A M, Salman S A K, et al. Evaluation of antibacterial and wound-healing activities of alcoholic extract of Boswellia carterii, in vitro and in vivo study [J]. J Cosmet Dermatol, 2022, 21(11): 6199-6208.
Mirshafiei M, Yazdi A, Beheshti S. Neuroprotective and anti-neuroinflammatory activity of frankincense in bile duct ligaion-induced hepatic encephalopathy [J]. Iran J Basic Med Sci, 2023, 26(8): 966-971.
Gunasekaran V, Avarachan J, Augustine A, et al. 3-O-acetyl-11-keto-β-boswellic acid ameliorates acquired, consolidated and recognitive memory deficits through the regulation of hippocampal PPAR γ, MMP9 and MMP2 genes in dementia model [J]. Heliyon, 2021, 7(12): e08523.
Liu T L, Bai M, Liu M N, et al. Novel synergistic mechanism of 11-keto-β-boswellic acid and Z-guggulsterone on ischemic stroke revealed by single-cell transcriptomics [J]. Pharmacol Res, 2023, 193: 106803.
Khan A, Khan I, Halim S A, et al. Anti-diabetic potential of β-boswellic acid and 11-keto-β-boswellic acid: Mechanistic insights from computational and biochemical approaches [J]. Biomed Pharmacother, 2022, 147: 112669.
Al-Matubsi H, Rashan L, Aburayyan W, et al. Antidiabetic and antioxidant properties of Boswellia sacra oleo-gum in streptozotocin-induced diabetic rats [J]. J Ayurveda Integr Med, 2024, 15(4): 101014.
Yu G P, Xiang W, Zhang T Q, et al. Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: A systematic review and Meta-analysis [J]. BMC Complement Med Ther, 2020, 20(1): 225.
Karlapudi V, Sunkara K B, Konda P R, et al. Efficacy and safety of Aflapin®, a novel Boswellia serrata extract, in the treatment of osteoarthritis of the knee: A short-term 30-day randomized, double-blind, placebo-controlled clinical study [J]. J Am Nutr Assoc, 2023, 42(2): 159-168.
Pérez-Piñero S, Muñoz-Carrillo J C, Victoria-Montesinos D, et al. Efficacy of Boswellia serrata extract and/or an omega-3-based product for improving pain and function in people older than 40 years with persistent knee pain: A randomized double-blind controlled clinical trial [J]. Nutrients, 2023, 15(17): 3848.)
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乳香化学成分及药理作用研究进展
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中草药 |综述 2026 , 57 (19) : 7922 -7928
乳香化学成分及药理作用研究进展
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佘一鸣1
作者信息
    1 天津市北辰医院, 天津 300400
作者简介:
佘一鸣: 佘一鸣,女,硕士,研究方向为中药。E-mail:ysg6767@163.com
Research progress on chemical constituents and pharmacological activities of Olibanum
  • SHE Yiming1
  • Affiliations
      1 Beichen Hospital of Tianjin, Tianjin 300400, China
    doi: 10.7501j.issn.0253-2670.2026.19.034
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    乳香是我国传统常用中药,具有活血止痛、消肿生肌等功效,临床应用历史悠久。从乳香中已分离鉴定出400余种化合物,其中二萜类和三萜类化合物为其主要活性成分。乳香及其活性成分具有抗炎、护肝、抗肿瘤等药理作用,其作用机制涉及抑制炎症介质释放、调控氧化应激等多个层面。综述了近几年乳香化学成分及药理作用的研究进展,以期为乳香的进一步开发利用及相关基础与临床研究提供参考。
    乳香  /  二萜类  /  三萜类  /  抗炎:抗肿瘤
    Ruxiang (Olibanum) is a commonly used traditional Chinese medicinal material with a long history of clinical application, and it is known for its effects of promoting blood circulation, relieving pain, reducing swelling, and promoting tissue regeneration. To date, more than 400 compounds have been isolated and identified from Olibanum, among which diterpenoids and triterpenoids are considered the major bioactive constituents. Olibanum and its active components exhibit a wide range of pharmacological activities, including anti-inflammatory, hepatoprotective, and antitumor effects. The underlying mechanisms involve multiple pathways, such as the inhibition of inflammatory mediator release and the regulation of oxidative stress. This review summarizes the recent advances in the chemical constituents and pharmacological activities of Olibanum, aiming to provide a reference for its further development and utilization, as well as for related basic and clinical research.
    Olibanum  /  diterpenoids  /  triterpenoids  /  anti-inflammatory  /  antitumor
    佘一鸣. 乳香化学成分及药理作用研究进展. 中草药, 2026 , 57 (19) : 7922 -7928 . DOI: 10.7501j.issn.0253-2670.2026.19.034
    SHE Yiming. Research progress on chemical constituents and pharmacological activities of Olibanum[J]. Chinese Traditional and Herbal Drugs, 2026 , 57 (19) : 7922 -7928 . DOI: 10.7501j.issn.0253-2670.2026.19.034

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    Shakir Abed Almjalawi B, Alhamed T A, Alhesnawi A S M. Antibacterial activity of Boswellia carterii aqueous extract and its effect on phagocytosis in vitro [J]. Arch Razi Inst, 2022, 77(2): 545-552.
    Gnedy M M A, Hussien R A A, Sleem R A, et al. In vitro efficacy of Boswellia carterii resin extracts formulated as an emulsifiable concentrate against Tetranychus urticae and phytopathogenic fungi [J]. Saudi J Biol Sci, 2023, 30(12): 103843.
    Hasson S O, Jasim A M, Salman S A K, et al. Evaluation of antibacterial and wound-healing activities of alcoholic extract of Boswellia carterii, in vitro and in vivo study [J]. J Cosmet Dermatol, 2022, 21(11): 6199-6208.
    Mirshafiei M, Yazdi A, Beheshti S. Neuroprotective and anti-neuroinflammatory activity of frankincense in bile duct ligaion-induced hepatic encephalopathy [J]. Iran J Basic Med Sci, 2023, 26(8): 966-971.
    Gunasekaran V, Avarachan J, Augustine A, et al. 3-O-acetyl-11-keto-β-boswellic acid ameliorates acquired, consolidated and recognitive memory deficits through the regulation of hippocampal PPAR γ, MMP9 and MMP2 genes in dementia model [J]. Heliyon, 2021, 7(12): e08523.
    Liu T L, Bai M, Liu M N, et al. Novel synergistic mechanism of 11-keto-β-boswellic acid and Z-guggulsterone on ischemic stroke revealed by single-cell transcriptomics [J]. Pharmacol Res, 2023, 193: 106803.
    Khan A, Khan I, Halim S A, et al. Anti-diabetic potential of β-boswellic acid and 11-keto-β-boswellic acid: Mechanistic insights from computational and biochemical approaches [J]. Biomed Pharmacother, 2022, 147: 112669.
    Al-Matubsi H, Rashan L, Aburayyan W, et al. Antidiabetic and antioxidant properties of Boswellia sacra oleo-gum in streptozotocin-induced diabetic rats [J]. J Ayurveda Integr Med, 2024, 15(4): 101014.
    Yu G P, Xiang W, Zhang T Q, et al. Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: A systematic review and Meta-analysis [J]. BMC Complement Med Ther, 2020, 20(1): 225.
    Karlapudi V, Sunkara K B, Konda P R, et al. Efficacy and safety of Aflapin®, a novel Boswellia serrata extract, in the treatment of osteoarthritis of the knee: A short-term 30-day randomized, double-blind, placebo-controlled clinical study [J]. J Am Nutr Assoc, 2023, 42(2): 159-168.
    Pérez-Piñero S, Muñoz-Carrillo J C, Victoria-Montesinos D, et al. Efficacy of Boswellia serrata extract and/or an omega-3-based product for improving pain and function in people older than 40 years with persistent knee pain: A randomized double-blind controlled clinical trial [J]. Nutrients, 2023, 15(17): 3848.
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    doi: 10.7501j.issn.0253-2670.2026.19.034
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    2种不同金属材料的力学参数
    科
    Family
    属数
    Number of
    genus
    种数
    Number of
    species
    占总种数比例
    Percentage of
    total species (%)
    属
    Genus
    种数
    Number of
    species
    占总种数比例
    Percentage of total
    species (%)
    鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
    小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
    多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
    红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
    小菇属 Mycena 11 5.26
    光柄菇属 Pluteus 5 2.39
    红菇属 Russula 17 8.13
    栓菌属 Trametes 5 2.39
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