Article(id=1322631271054946426, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1322631228000424183, articleNumber=null, orderNo=null, doi=10.7501/j.issn.0253-2670.2026.18.031, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1773417600000, receivedDateStr=2026-03-14, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1793269468319, onlineDateStr=2026-10-29, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1793269468319, onlineIssueDateStr=2026-10-29, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1793269468319, creator=13701087609, updateTime=1793269468319, updator=13701087609, issue=Issue{id=1322631228000424183, tenantId=1146029695717560320, journalId=1302319053441957962, year='2026', volume='57', issue='18', pageStart='7073', pageEnd='7500', issueExtLink='null', onlineDate='null', pubDate='1790524800000', pubDateStr='2026-09-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1793269458054, creator='13701087609', updateTime=1793269548245, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1322631606339228314, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1322631228000424183, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1322631606339228315, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1322631228000424183, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=7451, endPage=7461, ext={EN=ArticleExt(id=1322631271679897725, articleId=1322631271054946426, tenantId=1146029695717560320, journalId=1302319053441957962, language=EN, title=Research progress and development trend of new high-efficiency extraction technologies for volatile oils from traditional Chinese medicine, columnId=null, journalTitle=Chinese Traditional and Herbal Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=Volatile oil in traditional Chinese medicine (TCM) is one of the important material bases for TCM to exert pharmacological effects, and its extraction technology directly determines the efficacy, safety and quality stability of the product. However, traditional extraction methods generally have problems such as low extraction efficiency, susceptible degradation of heat-sensitive constituents, and organic solvent residues, which seriously affect the quality and large-scale application of volatile oils. Therefore, the development of green and efficient new extraction technologies has become a key direction to promote technological progress in this field. This paper systematically summarizes the application status and inherent limitations of conventional extraction technologies such as solvent extraction and steam distillation, and discusses the research strategies to improve the efficiency of traditional methods through process parameter optimization, equipment structure improvement, and combination of ultrasonic, microwave and other physics auxiliary technologies. At the same time, the latest technical progress and research overview of emerging technologies such as supercritical fluid extraction, subcritical extraction, ultrasound-assisted extraction, microwave-assisted extraction, ionic liquid extraction and pulsed electric field-assisted extraction are summarized. Finally, the future development trends of multi-technology collaboration, green solvent substitution and intelligent regulation system construction are prospected, providing references for the innovation and industrial application of TCM volatile oil extraction technologies., authors=ZHAO Meirun1,2, JIANG Wan1, ZHANG Yao1, FU Yi1, LUO Wenyu1, ZHANG Puzhao1, ZHENG Qin1,3, QI Xiaoxu2, WU Zhenfeng1,2, YUE Pengfei1,2, authorsList=ZHAO Meirun, JIANG Wan, ZHANG Yao, FU Yi, LUO Wenyu, ZHANG Puzhao, ZHENG Qin, QI Xiaoxu, WU Zhenfeng, YUE Pengfei, authorCompany=1 Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Chinese Medicine, Nanchang 330004, China; 2 State Key Laboratory of Classical and Famous Prescriptions for Modern Chinese Medicine Creation, China Resources Jiangzhong Pharmaceutical Co., Ltd., Nanchang 330004, China; 3 Traditional Chinese Medicine Pharmaceutical Technology Collaborative Innovation Institute, Jiangxi University of Chinese Medicine, Nanchang 330004, China, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1322631271600205948, articleId=1322631271054946426, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=中药挥发油高效提取新技术进展与发展趋势, columnId=1304140194685415572, journalTitle=中草药, columnName=综述, runingTitle=null, highlight=null, 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articleText=null, reference=Tian B R, Liu J Y, Yang W, et al. Biopolymer food packaging films incorporated with essential oils[J]. J Agric Food Chem, 2023, 71(3):1325-1347. 陈军,何天雨,燕妮,等.基于药性特征的中药挥发油透皮促渗“热者易效”规律与机制[J]. 中草药, 2024,55(20):7144-7154. 王晓禹,吴国泰,杜丽东,等.中药挥发油新型制剂及其质量控制的研究现状[J]. 中国药房, 2021, 32(20):2551-2555. 齐明月,郭红叶,谢晨琼,等.基于指南/教材研究经典咳嗽治疗方的药味配伍规律[J]. 世界科学技术-中医药现代化, 2025(9):2654-2665. Li L, Du Y Y, Wang Y, et al. Atractylone alleviates ethanolinduced gastric ulcer in rat with altered gut microbiota and metabolites[J]. J Inflamm Res, 2022, 15:4709-4723. 吴婷婷,杜清,余欣然,等.香薷挥发油化学成分及药理活性研究进展[J]. 中成药, 2025, 47(5):1574-1581. 涂招秀,付建平,饶玉喜,等.有机溶剂法提取南方红豆杉茎叶中挥发油的工艺研究[J]. 江西科学, 2018,36(6):916-918. 姚雪峰,洪海龙,石俊庭,等.有机溶剂法和超临界CO2萃取法提取蒙艾挥发油的对比研究[J]. 广州化工, 2020, 48(23):55-57. Aziz Z A A, Ahmad A, Setapar S H M, et al. Essential oils:Extraction techniques, pharmaceutical and therapeutic potential-A review[J]. Curr Drug Metab, 2018, 19(13):1100-1110. Visakh N U, Pathrose B, Narayanankutty A, et al.Utilization of pomelo(Citrus maxima)peel waste into bioactive essential oils:Chemical composition and insecticidal properties[J]. Insects, 2022, 13(5):480. 邰佳,邹俊波,史亚军,等. GC-MS分析水蒸气蒸馏法提取石菖蒲挥发油过程中油水分配规律[J]. 中草药,2020, 51(1):59-66. 马贝娜,白昀川,宋萍,等.中药挥发油提取精制技术研究进展[J]. 中华中医药杂志, 2022, 37(11):6606-6610. 张小飞,詹娟娟,吴司琪,等.当归挥发油提取工艺优化及其乳化芳香水成分分析[J]. 中国实验方剂学杂志, 2017, 23(5):27-31. 张贵民,王永刚,纪红英,等.高效挥发油提取设备:中国, CN113845980B[P]. 2025-01-14. 王学成,伍振峰,杨明,等.中药挥发油微波真空提取装置及提取方法:中国, CN117025302A[P]. 2023-11-10. 张贵民,李艳芳,范建伟,等.一种新型挥发油提取器:中国, CN212357185U[P]. 2021-01-15. Yu H, Ren X N, Liu Y L, et al. Extraction of Cinnamomum camphora chvar. Borneol essential oil using neutral cellulase assisted-steam distillation:Optimization of extraction, and analysis of chemical constituents[J]. Ind Crops Prod, 2019, 141:111794. Park M K, Cha J Y, Kang M C, et al. The effects of different extraction methods on essential oils from orange and tangor:From the peel to the essential oil[J]. Food Sci Nutr, 2024, 12(2):804-814. He L H, Zhang L J, Bai X. Comparison of three different extraction methods on Schizonepeta tenuifolia(Benth.)briq essential oil:Chemical constituents and in vitro and in silico biological activities[J]. Chem Biodivers, 2025,22(2):e202401964. Bodea I M, Baenas-Soto A B, Garre A, et al. Enhancing essential oil extraction from orange peels using ultrasoundassisted hydro-distillation:A sustainable approach[J]. J Clean Prod, 2026, 552:147980. Uwineza P A, Waśkiewicz A. Recent advances in supercritical fluid extraction of natural bioactive compounds from natural plant materials[J]. Molecules,2020, 25(17):3847. Bin Nabi M H, Ahmed M M, Mia M S, et al. Essential oils:Advances in extraction techniques, chemical composition,bioactivities, and emerging applications[J]. Food Chem Adv, 2025, 8:101048. Arumugham T, Rambabu K, Hasan S W, et al.Supercritical carbon dioxide extraction of plant phytochemicals for biological and environmental applications-a review[J]. Chemosphere, 2021, 271:129525. Wu H, Li J L, Jia Y, et al. Essential oil extracted from Cymbopogon citronella leaves by supercritical carbon dioxide:Antioxidant and antimicrobial activities[J]. J Anal Meth Chem, 2019, 2019(1):8192439. Zhang H X, Huang T, Liao X N, et al. Extraction of camphor tree essential oil by steam distillation and supercritical CO2 extraction[J]. Molecules, 2022, 27(17):5385. 郭家刚,杨松,伍玉菡,等.超临界萃取结合分子蒸馏纯化生姜精油及其挥发性成分分析[J]. 食品与发酵工业, 2024, 50(3):224-231. Liu Z Z, Zu Y G, Yang L. A process to preserve valuable compounds and acquire essential oils from pomelo flavedo using a microwave irradiation treatment[J]. Food Chem,2017, 224:172-180. Zhang Y, Hawboldt K, MacQuarrie S. Extraction of bioactive compounds from beach-cast brown algae:A review on accelerated solvent extraction and subcritical water extraction[J]. RSC Sustain, 2024, 2(8):2069-2091. Somat H A, Thani N M, Mustapha W A W, et al.Subcritical water extraction of bioactive compounds from plant materials:Recent advances[J]. J Future Foods,2026, 6(5):753-764. Samadi M, Zainal Abidin Z, Yoshida H, et al. Towards higher oil yield and quality of essential oil extracted from Aquilaria malaccensis wood via the subcritical technique[J]. Molecules, 2020, 25(17):3872. Liu J Y, Li L, Wu W, et al. Green extraction of active ingredients from finger citron using subcritical water and assessment of antioxidant activity[J]. Ind Crops Prod,2023, 200:116821. 沈汝青,朱力,冯志豪,等.亚临界流体萃取沉香挥发油工艺的优化及精制精油测定[J]. 中成药, 2019,41(7):1495-1501. Cheng Y, Xue F M, Yu S, et al. Subcritical water extraction of natural products[J]. Molecules, 2021, 26(13):4004. Lim S H, Ko M J. Extraction characteristics and hydrolysis of flavoring compounds of cinnamon(Cinnamomum zeylanicum)under subcritical-water conditions[J]. Food Chem, 2022, 388:133029. Lee H Y, Ko M J. Thermal decomposition and oxidation ofβ-caryophyllene in black pepper during subcritical water extraction[J]. Food Sci Biotechnol, 2021, 30(12):1527-1533. Zekovic'Z, Kaplan M, Pavlic'B, et al. Chemical characterization of polyphenols and volatile fraction of coriander(Coriandrum sativum L.)extracts obtained by subcritical water extraction[J]. Ind Crops Prod, 2016, 87:54-63. Endy Yulianto M, Paramita V, Amalia R, et al. Production of bioactive compounds from ginger(Zingiber officianale)dregs through subcritical water extraction[J]. Mater Today Proc, 2022, 63:S188-S194. Chiou T Y, Nomura S, Konishi M, et al. Conversion and hydrothermal decomposition of major components of mint essential oil by small-scale subcritical water treatment[J]. Molecules, 2020, 25(8):1953. 杨妞妞,谢智锋,吕丹,等.超声辅助低共熔溶剂提取瓜蒌籽挥发油工艺优化及其抗氧化活性研究[J]. 天然产物研究与开发, 2025, 37(7):1310-1321. 王娟,袁绍莉,王丹.超声辅助水蒸气蒸馏法提取肉豆蔻挥发油及其抗氧化活性研究[J]. 粮食与油脂, 2022,35(9):81-85. Yingngam B, Navabhatra A, Brantner A. Increasing the essential oil yield from Shorea roxburghii inflorescences using an eco-friendly solvent-free microwave extraction method for fragrance applications[J]. J Appl Res Med Aromat Plants, 2021, 24:100332. Wang Z H, Zhao R, Gao H F, et al. Solvent-free microwave extraction of essential oil and hydrosol from fresh leaves of Cinnamomum burmannii(Nees et T. Nees)Blume after screw extrusion treatment and evaluation of pancreatic lipase inhibitory activities in vitro compared to its main components[J]. Ind Crops Prod, 2023, 202:116983. Wei L, Yu X X, Li H, et al. Optimization of solvent-free microwave extraction of essential oil from the fresh peel of Citrus medica L. var. arcodactylis Swingle by response surface methodology, chemical composition and activity characterization[J]. Sci Hortic, 2023, 309:111663. 李欠,尹转霖,丁小琴,等.独活挥发油低共熔溶剂辅助微波水蒸气蒸馏法提取及质量标志物(Q-Marker)研究[J]. 中草药, 2024, 55(4):1167-1177. Usuki T, Munakata K. Extraction of essential oils from the flowers of Osmanthus fragrans var. aurantiacus using an ionic liquid[J]. Bull Chem Soc Jpn, 2017, 90(10):1105-1110. Franco-Vega A, López-Malo A, Palou E, et al. Effect of imidazolium ionic liquids as microwave absorption media for the intensification of microwave-assisted extraction of Citrus sinensis peel essential oils[J]. Chem Eng Process Process Intensif, 2021, 160:108277. 鲁鹏,程伟琴,冯明,等.离子液体在萃取-火焰原子吸收分光光度法测定水中痕量铜的应用[J]. 化学工程师, 2020, 34(9):81-84. 唐一梅,张博,房海娜,等.离子液体辅助提取石菖蒲挥发油的工艺研究[J]. 西北大学学报:自然科学版,2018, 48(3):393-398. Ranjha M M A N, Kanwal R, Shafique B, et al. A critical review on pulsed electric field:A novel technology for the extraction of phytoconstituents[J]. Molecules, 2021,26(16):4893. Sadowska U, Matwijczuk A, Niemczynowicz A, et al.Spectroscopic examination and chemometric analysis of essential oils obtained from peppermint herb(Mentha piperita L.)and caraway fruit(Carum carvi L.)subjected to pulsed electric fields[J]. Processes, 2019, 7(7):466. Destryana R A, Estiasih T, Sukardi S, et al.Physicochemical and biological activities of Alpinia galanga(L.)Willd. essential oil extracted by pulsed electric field and ultrasonication pretreatments of hydrodistillation[J]. Trends Sci, 2025, 22(12):11087. Barros M, Redondo L, Rego D, et al. Extraction of essential oils from plants by hydrodistillation with pulsed electric fields(PEF)pre-treatment[J]. Appl Sci, 2022,12(16):8107. Gu Y C, Lv B Y, Xie X R, et al. Antibacterial mechanism of pulsed electric field-assisted extracted volatile oil from Wurfbainia villosa leaves against Escherichia coli and Staphylococcus aureus[J]. Front Microbiol, 2026, 17:1828154.)
Research progress and development trend of new high-efficiency extraction technologies for volatile oils from traditional Chinese medicine
ZHAO Meirun1,2, JIANG Wan1, ZHANG Yao1, FU Yi1, LUO Wenyu1, ZHANG Puzhao1, ZHENG Qin1,3, QI Xiaoxu2, WU Zhenfeng1,2, YUE Pengfei1,2
Affiliations
1 Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Chinese Medicine, Nanchang 330004, China; 2 State Key Laboratory of Classical and Famous Prescriptions for Modern Chinese Medicine Creation, China Resources Jiangzhong Pharmaceutical Co., Ltd., Nanchang 330004, China; 3 Traditional Chinese Medicine Pharmaceutical Technology Collaborative Innovation Institute, Jiangxi University of Chinese Medicine, Nanchang 330004, China
Volatile oil in traditional Chinese medicine (TCM) is one of the important material bases for TCM to exert pharmacological effects, and its extraction technology directly determines the efficacy, safety and quality stability of the product. However, traditional extraction methods generally have problems such as low extraction efficiency, susceptible degradation of heat-sensitive constituents, and organic solvent residues, which seriously affect the quality and large-scale application of volatile oils. Therefore, the development of green and efficient new extraction technologies has become a key direction to promote technological progress in this field. This paper systematically summarizes the application status and inherent limitations of conventional extraction technologies such as solvent extraction and steam distillation, and discusses the research strategies to improve the efficiency of traditional methods through process parameter optimization, equipment structure improvement, and combination of ultrasonic, microwave and other physics auxiliary technologies. At the same time, the latest technical progress and research overview of emerging technologies such as supercritical fluid extraction, subcritical extraction, ultrasound-assisted extraction, microwave-assisted extraction, ionic liquid extraction and pulsed electric field-assisted extraction are summarized. Finally, the future development trends of multi-technology collaboration, green solvent substitution and intelligent regulation system construction are prospected, providing references for the innovation and industrial application of TCM volatile oil extraction technologies.
ZHAO Meirun, JIANG Wan, ZHANG Yao, FU Yi, LUO Wenyu, ZHANG Puzhao, ZHENG Qin, QI Xiaoxu, WU Zhenfeng, YUE Pengfei.
Research progress and development trend of new high-efficiency extraction technologies for volatile oils from traditional Chinese medicine[J].
Chinese Traditional and Herbal Drugs,
2026
, 57
(18)
: 7451
-7461
.
DOI: 10.7501/j.issn.0253-2670.2026.18.031
Tian B R, Liu J Y, Yang W, et al. Biopolymer food packaging films incorporated with essential oils[J]. J Agric Food Chem, 2023, 71(3):1325-1347. 陈军,何天雨,燕妮,等.基于药性特征的中药挥发油透皮促渗“热者易效”规律与机制[J]. 中草药, 2024,55(20):7144-7154. 王晓禹,吴国泰,杜丽东,等.中药挥发油新型制剂及其质量控制的研究现状[J]. 中国药房, 2021, 32(20):2551-2555. 齐明月,郭红叶,谢晨琼,等.基于指南/教材研究经典咳嗽治疗方的药味配伍规律[J]. 世界科学技术-中医药现代化, 2025(9):2654-2665. Li L, Du Y Y, Wang Y, et al. Atractylone alleviates ethanolinduced gastric ulcer in rat with altered gut microbiota and metabolites[J]. J Inflamm Res, 2022, 15:4709-4723. 吴婷婷,杜清,余欣然,等.香薷挥发油化学成分及药理活性研究进展[J]. 中成药, 2025, 47(5):1574-1581. 涂招秀,付建平,饶玉喜,等.有机溶剂法提取南方红豆杉茎叶中挥发油的工艺研究[J]. 江西科学, 2018,36(6):916-918. 姚雪峰,洪海龙,石俊庭,等.有机溶剂法和超临界CO2萃取法提取蒙艾挥发油的对比研究[J]. 广州化工, 2020, 48(23):55-57. Aziz Z A A, Ahmad A, Setapar S H M, et al. Essential oils:Extraction techniques, pharmaceutical and therapeutic potential-A review[J]. Curr Drug Metab, 2018, 19(13):1100-1110. Visakh N U, Pathrose B, Narayanankutty A, et al.Utilization of pomelo(Citrus maxima)peel waste into bioactive essential oils:Chemical composition and insecticidal properties[J]. Insects, 2022, 13(5):480. 邰佳,邹俊波,史亚军,等. GC-MS分析水蒸气蒸馏法提取石菖蒲挥发油过程中油水分配规律[J]. 中草药,2020, 51(1):59-66. 马贝娜,白昀川,宋萍,等.中药挥发油提取精制技术研究进展[J]. 中华中医药杂志, 2022, 37(11):6606-6610. 张小飞,詹娟娟,吴司琪,等.当归挥发油提取工艺优化及其乳化芳香水成分分析[J]. 中国实验方剂学杂志, 2017, 23(5):27-31. 张贵民,王永刚,纪红英,等.高效挥发油提取设备:中国, CN113845980B[P]. 2025-01-14. 王学成,伍振峰,杨明,等.中药挥发油微波真空提取装置及提取方法:中国, CN117025302A[P]. 2023-11-10. 张贵民,李艳芳,范建伟,等.一种新型挥发油提取器:中国, CN212357185U[P]. 2021-01-15. Yu H, Ren X N, Liu Y L, et al. Extraction of Cinnamomum camphora chvar. Borneol essential oil using neutral cellulase assisted-steam distillation:Optimization of extraction, and analysis of chemical constituents[J]. Ind Crops Prod, 2019, 141:111794. Park M K, Cha J Y, Kang M C, et al. The effects of different extraction methods on essential oils from orange and tangor:From the peel to the essential oil[J]. Food Sci Nutr, 2024, 12(2):804-814. He L H, Zhang L J, Bai X. Comparison of three different extraction methods on Schizonepeta tenuifolia(Benth.)briq essential oil:Chemical constituents and in vitro and in silico biological activities[J]. Chem Biodivers, 2025,22(2):e202401964. Bodea I M, Baenas-Soto A B, Garre A, et al. Enhancing essential oil extraction from orange peels using ultrasoundassisted hydro-distillation:A sustainable approach[J]. J Clean Prod, 2026, 552:147980. Uwineza P A, Waśkiewicz A. Recent advances in supercritical fluid extraction of natural bioactive compounds from natural plant materials[J]. Molecules,2020, 25(17):3847. Bin Nabi M H, Ahmed M M, Mia M S, et al. Essential oils:Advances in extraction techniques, chemical composition,bioactivities, and emerging applications[J]. Food Chem Adv, 2025, 8:101048. Arumugham T, Rambabu K, Hasan S W, et al.Supercritical carbon dioxide extraction of plant phytochemicals for biological and environmental applications-a review[J]. Chemosphere, 2021, 271:129525. Wu H, Li J L, Jia Y, et al. Essential oil extracted from Cymbopogon citronella leaves by supercritical carbon dioxide:Antioxidant and antimicrobial activities[J]. J Anal Meth Chem, 2019, 2019(1):8192439. Zhang H X, Huang T, Liao X N, et al. Extraction of camphor tree essential oil by steam distillation and supercritical CO2 extraction[J]. Molecules, 2022, 27(17):5385. 郭家刚,杨松,伍玉菡,等.超临界萃取结合分子蒸馏纯化生姜精油及其挥发性成分分析[J]. 食品与发酵工业, 2024, 50(3):224-231. Liu Z Z, Zu Y G, Yang L. A process to preserve valuable compounds and acquire essential oils from pomelo flavedo using a microwave irradiation treatment[J]. Food Chem,2017, 224:172-180. Zhang Y, Hawboldt K, MacQuarrie S. Extraction of bioactive compounds from beach-cast brown algae:A review on accelerated solvent extraction and subcritical water extraction[J]. RSC Sustain, 2024, 2(8):2069-2091. Somat H A, Thani N M, Mustapha W A W, et al.Subcritical water extraction of bioactive compounds from plant materials:Recent advances[J]. J Future Foods,2026, 6(5):753-764. Samadi M, Zainal Abidin Z, Yoshida H, et al. Towards higher oil yield and quality of essential oil extracted from Aquilaria malaccensis wood via the subcritical technique[J]. Molecules, 2020, 25(17):3872. Liu J Y, Li L, Wu W, et al. Green extraction of active ingredients from finger citron using subcritical water and assessment of antioxidant activity[J]. Ind Crops Prod,2023, 200:116821. 沈汝青,朱力,冯志豪,等.亚临界流体萃取沉香挥发油工艺的优化及精制精油测定[J]. 中成药, 2019,41(7):1495-1501. Cheng Y, Xue F M, Yu S, et al. Subcritical water extraction of natural products[J]. Molecules, 2021, 26(13):4004. Lim S H, Ko M J. Extraction characteristics and hydrolysis of flavoring compounds of cinnamon(Cinnamomum zeylanicum)under subcritical-water conditions[J]. Food Chem, 2022, 388:133029. Lee H Y, Ko M J. Thermal decomposition and oxidation ofβ-caryophyllene in black pepper during subcritical water extraction[J]. Food Sci Biotechnol, 2021, 30(12):1527-1533. Zekovic'Z, Kaplan M, Pavlic'B, et al. Chemical characterization of polyphenols and volatile fraction of coriander(Coriandrum sativum L.)extracts obtained by subcritical water extraction[J]. Ind Crops Prod, 2016, 87:54-63. Endy Yulianto M, Paramita V, Amalia R, et al. Production of bioactive compounds from ginger(Zingiber officianale)dregs through subcritical water extraction[J]. Mater Today Proc, 2022, 63:S188-S194. Chiou T Y, Nomura S, Konishi M, et al. Conversion and hydrothermal decomposition of major components of mint essential oil by small-scale subcritical water treatment[J]. Molecules, 2020, 25(8):1953. 杨妞妞,谢智锋,吕丹,等.超声辅助低共熔溶剂提取瓜蒌籽挥发油工艺优化及其抗氧化活性研究[J]. 天然产物研究与开发, 2025, 37(7):1310-1321. 王娟,袁绍莉,王丹.超声辅助水蒸气蒸馏法提取肉豆蔻挥发油及其抗氧化活性研究[J]. 粮食与油脂, 2022,35(9):81-85. Yingngam B, Navabhatra A, Brantner A. Increasing the essential oil yield from Shorea roxburghii inflorescences using an eco-friendly solvent-free microwave extraction method for fragrance applications[J]. J Appl Res Med Aromat Plants, 2021, 24:100332. Wang Z H, Zhao R, Gao H F, et al. Solvent-free microwave extraction of essential oil and hydrosol from fresh leaves of Cinnamomum burmannii(Nees et T. Nees)Blume after screw extrusion treatment and evaluation of pancreatic lipase inhibitory activities in vitro compared to its main components[J]. Ind Crops Prod, 2023, 202:116983. Wei L, Yu X X, Li H, et al. Optimization of solvent-free microwave extraction of essential oil from the fresh peel of Citrus medica L. var. arcodactylis Swingle by response surface methodology, chemical composition and activity characterization[J]. Sci Hortic, 2023, 309:111663. 李欠,尹转霖,丁小琴,等.独活挥发油低共熔溶剂辅助微波水蒸气蒸馏法提取及质量标志物(Q-Marker)研究[J]. 中草药, 2024, 55(4):1167-1177. Usuki T, Munakata K. Extraction of essential oils from the flowers of Osmanthus fragrans var. aurantiacus using an ionic liquid[J]. Bull Chem Soc Jpn, 2017, 90(10):1105-1110. Franco-Vega A, López-Malo A, Palou E, et al. Effect of imidazolium ionic liquids as microwave absorption media for the intensification of microwave-assisted extraction of Citrus sinensis peel essential oils[J]. Chem Eng Process Process Intensif, 2021, 160:108277. 鲁鹏,程伟琴,冯明,等.离子液体在萃取-火焰原子吸收分光光度法测定水中痕量铜的应用[J]. 化学工程师, 2020, 34(9):81-84. 唐一梅,张博,房海娜,等.离子液体辅助提取石菖蒲挥发油的工艺研究[J]. 西北大学学报:自然科学版,2018, 48(3):393-398. Ranjha M M A N, Kanwal R, Shafique B, et al. A critical review on pulsed electric field:A novel technology for the extraction of phytoconstituents[J]. Molecules, 2021,26(16):4893. Sadowska U, Matwijczuk A, Niemczynowicz A, et al.Spectroscopic examination and chemometric analysis of essential oils obtained from peppermint herb(Mentha piperita L.)and caraway fruit(Carum carvi L.)subjected to pulsed electric fields[J]. Processes, 2019, 7(7):466. Destryana R A, Estiasih T, Sukardi S, et al.Physicochemical and biological activities of Alpinia galanga(L.)Willd. essential oil extracted by pulsed electric field and ultrasonication pretreatments of hydrodistillation[J]. Trends Sci, 2025, 22(12):11087. Barros M, Redondo L, Rego D, et al. Extraction of essential oils from plants by hydrodistillation with pulsed electric fields(PEF)pre-treatment[J]. Appl Sci, 2022,12(16):8107. Gu Y C, Lv B Y, Xie X R, et al. Antibacterial mechanism of pulsed electric field-assisted extracted volatile oil from Wurfbainia villosa leaves against Escherichia coli and Staphylococcus aureus[J]. Front Microbiol, 2026, 17:1828154.