Article(id=1304415560398296006, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304415531491152712, articleNumber=null, orderNo=null, doi=10.7501/j.issn.0253-2670.2026.09.022, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1764604800000, receivedDateStr=2025-12-02, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788926504468, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788926504468, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788926504468, creator=13701087609, updateTime=1788926504468, updator=13701087609, issue=Issue{id=1304415531491152712, tenantId=1146029695717560320, journalId=1302319053441957962, year='2026', volume='57', issue='9', pageStart='3261', pageEnd='3684', issueExtLink='null', onlineDate='null', pubDate='1778515200000', pubDateStr='2026-05-12', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788926497576, creator='13701087609', updateTime=1788926796984, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304416787358049066, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304415531491152712, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304416787358049067, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304415531491152712, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=3538, endPage=3547, ext={EN=ArticleExt(id=1304415560712868808, articleId=1304415560398296006, tenantId=1146029695717560320, journalId=1302319053441957962, language=EN, title=Dynamic study on accumulation of secondary metabolites in leaves of Acanthopanax senticosus during growth season, columnId=null, journalTitle=Chinese Traditional and Herbal Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective To clarify the dynamic accumulation pattern of secondary metabolites in the leaves of Acanthopanax senticosus during the growth season, providing theoretical support for precision-guided leaf harvesting tailored to different usage purposes. Methods Colorimetric method and untargeted metabolomics technology were used to analyze the dynamic accumulation characteristics of metabolites such as flavonoids, polyphenols and saponins in the leaves of A. senticosus. Results The growth season was divided into 13 stages (L1—L13) based on leaf morphodevelopmental traits. Total flavonoids, polyphenols, triterpenoids, and saponins exhibited bimodal accumulation peaks at L3 (the peak leaf expansion stage) and L11 (the end of July), with maximum contents at L11, reaching 8.02-, 1.68-, 1.61-, and 1.63-fold increases, respectively, compared to L1. KEGG enrichment analysis revealed that, relative to L3, L11 showed specific upregulation of phenylpropanoid and flavonoid biosynthesis pathways, coupled with synergistic accumulation of light signaling molecules (FAD, lumiflavin) and defense-related compounds (sinapine, quercetin glycosides), while nucleotide synthesis precursors significantly decreased. Additionally, the pharmacopoeial quality control indicator syringin increased by 2.51-fold in L11 relative to L3. Conclusion The secondary metabolism of A. senticosus leaves exhibits significant developmental stage-dependence, among which the L11 stage is a high-enrichment period, this provides metabolomic evidence for the precise utilization of A. senticosus leaves., authors=TONG Yaqian, GAO Xinglei, TANG Zhonghua, ZHOU Yaxin, CHENG Cheng, FAN Guizhi, authorsList=TONG Yaqian, GAO Xinglei, TANG Zhonghua, ZHOU Yaxin, CHENG Cheng, FAN Guizhi, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1304415560628982727, articleId=1304415560398296006, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=刺五加叶中次生代谢物在生长季的动态累积研究, columnId=1304140203967410414, journalTitle=中草药, columnName=药材与资源, runingTitle=null, highlight=null, articleAbstract=目的 明确刺五加Acanthopanax senticosus叶中次生代谢物在生长季内的动态积累规律，为不同用途叶片的精准采收提供理论依据。方法 运用比色法和非靶代谢组学技术，分析刺五加叶中黄酮、多酚和皂苷等代谢物的动态累积特征。结果 基于叶片的形态发育特征将生长季划分为13个时期（L1～L13），总黄酮、总多酚、总三萜及总皂苷含量呈现L3（展叶盛期）和L11（7月末）双峰积累模式，其中L11期各组分含量达最大值，较L1期分别提升8.02、1.68、1.61和1.63倍。基因组百科全书（Kyoto encyclopedia of genes and genomes，KEGG）富集分析显示，与L3期相比，L11期苯丙烷和类黄酮生物合成通路特异性上调，光信号分子（FAD、光黄素）与防御相关化合物（芥子碱、槲皮素糖苷）协同积累，而核苷酸合成前体显著减少。此外，《中国药典》质控指标紫丁香苷在L11期的相对含量较L3期增加2.51倍；结论 刺五加叶中次生代谢的累积具有显著的发育阶段依赖性，其中L11期是高富集期，这为刺五加叶片的精准利用提供了代谢组学依据。, authors=仝亚倩¹, 高兴蕾¹, 唐中华², 周雅欣¹, 程程², 范桂枝¹, authorsList=仝亚倩, 高兴蕾, 唐中华, 周雅欣, 程程, 范桂枝, authorCompany=1 东北林业大学生命科学学院, 黑龙江 哈尔滨 150040;
2 东北林业大学化学化工与资源利用学院, 黑龙江 哈尔滨 150040, correspAuthors=范桂枝, authorNote=仝亚倩: 仝亚倩,硕士研究生,从事植物细胞工程领域研究。E-mail:2252113828@qq.com, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=ZfEFVuVnakV15N+bmwl1RQ==, pdfFileSize=1923662, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=四川省自然科学基金项目（面上项目）(2026NSFSC0614);四川省自然科学基金项目（青年基金项目）(2025ZNSFSC1821);2023年全国中药特色技术传承人才培训项目(T20234832005))}, authors=null, keywords=[Keyword(id=1304415560834503625, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=CN, orderNo=1, keyword=刺五加), Keyword(id=1304415563921511370, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=CN, orderNo=2, keyword=叶), Keyword(id=1304415563997008843, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=CN, orderNo=3, keyword=次生代谢物), Keyword(id=1304415564055729100, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=CN, orderNo=4, keyword=动态积累), Keyword(id=1304415564127032269, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=CN, orderNo=5, keyword=非靶代谢组学), Keyword(id=1304415564189946830, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=CN, orderNo=6, keyword=总黄酮), Keyword(id=1304415564265444303, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=CN, orderNo=7, keyword=总多酚), Keyword(id=1304415564328358864, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=CN, orderNo=8, keyword=总三萜), Keyword(id=1304415564395467729, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=CN, orderNo=9, keyword=总皂苷), Keyword(id=1304415564479353810, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=EN, orderNo=1, keyword=Acanthopanax senticosus (Rupr. et Maxim.) Harms), Keyword(id=1304415564563239891, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=EN, orderNo=2, keyword=leaf), Keyword(id=1304415564638737364, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=EN, orderNo=3, keyword=secondary metabolites), Keyword(id=1304415564693263317, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=EN, orderNo=4, keyword=dynamic accumulation), Keyword(id=1304415564806509526, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=EN, orderNo=5, keyword=untargeted metabolomics), Keyword(id=1304415564890395607, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=EN, orderNo=6, keyword=total flavonoids), Keyword(id=1304415564974281688, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=EN, orderNo=7, keyword=total polyphenols), Keyword(id=1304415565041390553, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=EN, orderNo=8, keyword=total triterpenoids), Keyword(id=1304415565104305114, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415560398296006, language=EN, orderNo=9, keyword=total saponins)], refs=null, funds=null, companyList=null, figs=null, attaches=null, journal=Journal(id=1302309778002903112, delFlag=0, nameCn=中草药, nameEn=Chinese Traditional and Herbal Drugs, nameHistory1=null, nameHistory2=null, issn=0253-2670, eissn=null, cn=12-1108/R, coden=null, periodic=3, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=cGpSKCP11AF8PAOcTXYWfg==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Traditional and Herbal Drugs, journalRemark=null, publicationField=null, createdTime=1788424446827, updatedTime=1788949289390, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=cGpSKCP11AF8PAOcTXYWfg==, picEn=Xw//kxUC3ON4eHxev0QLhQ==, jcr=null, cjcr=null, exts=[JournalExt(id=1304511127375863983, language=CN, name=中草药, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949289411, updatedTime=1788949289411, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://www.tiprpress.com/zcy/author/login, submissionEditorUrl=https://www.tiprpress.com/zcy/editor/login, submissionReviewUrl=https://www.tiprpress.com/zcy/reviewer/login, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1304511127442972848, language=EN, name=Chinese Traditional and Herbal Drugs, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949289427, updatedTime=1788949289427, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://www.tiprpress.com/zcy/author/login, submissionEditorUrl=https://www.tiprpress.com/zcy/editor/login, submissionReviewUrl=https://www.tiprpress.com/zcy/reviewer/login, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1302319053441957962, websiteList=[Website(id=1302319176408912052, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1302319053441957962, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zcy/CN, language=CN, createTime=1788426687576, createBy=18614031015, updateTime=1788427346252, updateBy=18614031015, name=中草药-中文, tplId=1146099689490845704, title=中草药, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1302322043651904087, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=articleTextType, value=kx, createTime=1788427371180, updateTime=1788427371180, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043593183828, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=banner, value=null, createTime=1788427371166, updateTime=1788427371166, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043672875610, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=grayFlag, value=0, createTime=1788427371185, updateTime=1788427371185, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043584795219, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=logo, value=https://castjournals.cast.org.cn/joweb/zcy/CN/file/pic?fileId=uiD1gpiRqR++OLOz4iKzDg==, createTime=1788427371164, updateTime=1788427371164, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043689652828, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=minRunFlag, value=0, createTime=1788427371189, updateTime=1788427371189, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043643515478, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zcy/CN/file/pic, createTime=1788427371178, updateTime=1788427371178, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043681264219, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=silenceFlag, value=0, createTime=1788427371187, updateTime=1788427371187, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043601572437, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1788427371168, updateTime=1788427371168, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043660292696, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=themeColor, value=null, createTime=1788427371182, updateTime=1788427371182, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043668681305, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=themeStyle, value=null, createTime=1788427371184, updateTime=1788427371184, creator=18614031015, updator=18614031015)]), Website(id=1302319176715096246, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1302319053441957962, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zcy/EN, language=EN, createTime=1788426687649, createBy=18614031015, updateTime=1788427341161, updateBy=18614031015, name=中草药-英文, tplId=1146101810881728533, title=Chinese Traditional and Herbal Drugs, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1302322015206134340, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=articleTextType, value=kx, createTime=1788427364398, updateTime=1788427364398, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015185162817, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=banner, value=null, createTime=1788427364393, updateTime=1788427364393, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015227105863, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=grayFlag, value=0, createTime=1788427364403, updateTime=1788427364403, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015176774208, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=logo, value=https://castjournals.cast.org.cn/joweb/zcy/EN/file/pic?fileId=uiD1gpiRqR++OLOz4iKzDg==, createTime=1788427364391, updateTime=1788427364391, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015239688777, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=minRunFlag, value=0, createTime=1788427364406, updateTime=1788427364406, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015201940035, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zcy/EN/file/pic, createTime=1788427364397, updateTime=1788427364397, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015235494472, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=silenceFlag, value=0, createTime=1788427364405, updateTime=1788427364405, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015193551426, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1788427364395, updateTime=1788427364395, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015214522949, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=themeColor, value=null, createTime=1788427364400, updateTime=1788427364400, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015218717254, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=themeStyle, value=null, createTime=1788427364401, updateTime=1788427364401, creator=18614031015, updator=18614031015)])], journalTitle=中草药, weixinUrl=null, journalUrl=https://www.tiprpress.com/zcy, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Traditional and Herbal Drugs, journalPhotoCn=cGpSKCP11AF8PAOcTXYWfg==, journalPhotoEn=Xw//kxUC3ON4eHxev0QLhQ==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zcy/CN/10.7501/j.issn.0253-2670.2026.09.022, detailUrlEn=https://castjournals.cast.org.cn/joweb/zcy/EN/10.7501/j.issn.0253-2670.2026.09.022, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zcy/CN/PDF/10.7501/j.issn.0253-2670.2026.09.022, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zcy/EN/PDF/10.7501/j.issn.0253-2670.2026.09.022, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1788926504468, fullTextJson=null, articleText=null, reference=仝梓莹,冯文斌,曹贵阳,等.黑龙江道地药材刺五加药用价值与资源评估研究[J].中国中医药图书情报杂志, 2025, 49(2):29-33.
国家卫生健康委员会.卫生部关于进一步规范保健食品原料管理的通知(卫法监发[2002] 51号)[Z]. 2002-02-28.
于淼,刘玉龙,王冰,等.刺五加抗肿瘤活性成分作用机制及其临床应用[J].中草药, 2024, 55(22):7897-7906.
Song C, Duan F Y, Ju T, et al. Eleutheroside E supplementation prevents radiation-induced cognitive impairment and activates PKA signaling via gut microbiota[J]. Commun Biol, 2022, 5(1):680.
王佳佳,王莹,谢莹,等.刺五加药理作用研究进展[J].特产研究, 2023, 45(6):173-177.
李强,张若冰,杨玉赫,等.刺五加叶化学成分及药理作用研究进展[J].药学研究, 2023, 42(7):495-501.
王欣宇,林花,刁春妍,等.刺五加果生物活性及其应用进展[J].农业与技术, 2023, 43(3):10-13.
吴郁,曲翔汝,杨丹,等.广泛非靶向代谢组学解析小麦抗条锈病反应中叶绿体代谢产物[J].中国农业科学, 2025, 58(7):1333-1343.
Zhang J G, Zhang Y, Zhang W W, et al. Differential metabolites analysis in Lycium barbarum and Platycodon grandiflorus fermented wine by untargeted metabolomics[J]. Appl Food Res, 2024, 4(2):100631.
杨晓萌,赵楠,刘欣欣,等.基于非靶向代谢组学的怀珍珠菊和野菊花化学成分差异性分析[J].中草药,2024, 55(19):6496-6507.
罗朝丹,冯春梅,李建强,等.基于GC-MS非靶向代谢组学分析不同成熟度'台农一号'芒果香气物质[J].中国农业科学, 2025, 58(3):564-581.
杨秀娟,魏江霞,杨志军,等.基于UHPLC-QE-MS非靶向代谢组学的当归不同药用部位差异代谢物分析[J].药学学报, 2025, 60(4):1093-1102.
Wolfe K, Wu X Z, Liu R H. Antioxidant activity of apple peels[J]. J Agric Food Chem, 2003, 51(3):609-614.
Pastrana-Bonilla E, Akoh C C, Sellappan S, et al. Phenolic content and antioxidant capacity of muscadine grapes[J].J Agric Food Chem, 2003, 51(18):5497-5503.
姜洋,孙菲菲,詹亚光,等.一氧化碳对白桦悬浮细胞生长和三萜累积的影响[J].中草药, 2019, 50(15):3681-3686.
初旸.刺五加细胞培养体系的建立与有效成分积累的调控研究[D].沈阳:沈阳药科大学, 2008.
Coley P D, Bryant J P, Chapin F S. Resource availability and plant antiherbivore defense[J]. Science, 1985,230(4728):895-899.
孟祥才,王喜军,孙晖,等.刺五加活性成分积累规律及其质量评价研究[J].中国中药杂志, 2011, 36(15):2021-2025.
代吉瑞,王春玲,李芝,等.刺五加叶片皂苷类成分动态积累规律研究[J].中药材, 2019, 42(3):547-551.
Wink M. Plant secondary metabolism:Diversity, function and its evolution[J]. Nat Prod Commun, 2008, 3(8):1934578X0800300801.
李俊萍,王雪梅,孙海峰,等.刺五加叶黄酮类成分动态积累及其与环境因子的相关性研究[J].中国中药杂志, 2019, 44(12):2563-2568.
Li C, Jiao M Y, Zhao X Y, et al. bZIP transcription factor responds to changes in light quality and affects saponins synthesis in Eleutherococcus senticosus[J]. Int J Biol Macromol, 2024, 279:135273.
Hirel B, Le Gouis J, Ney B, et al. The challenge of improving nitrogen use efficiency in crop plants:Towards a more central role for genetic variability and quantitative genetics within integrated approaches[J]. J Exp Bot, 2007,58(9):2369-2387.
Breton C,ŠnajdrováL, Jeanneau C, et al. Structures and mechanisms of glycosyltransferases[J]. Glycobiology,2006, 16(2):29R-37R.
陆珞,阎墨,赵晓红,等. HPLC法测定不同采收期刺五加叶中丁香苷的含量[J].人参研究, 2011, 23(3):15-18.)