Article(id=1304415533345035094, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304415531491152712, articleNumber=null, orderNo=null, doi=10.7501/j.issn.0253-2670.2026.09.003, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1770739200000, receivedDateStr=2026-02-11, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788926498018, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788926498018, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788926498018, creator=13701087609, updateTime=1788926498018, updator=13701087609, issue=Issue{id=1304415531491152712, tenantId=1146029695717560320, journalId=1302319053441957962, year='2026', volume='57', issue='9', pageStart='3261', pageEnd='3684', issueExtLink='null', onlineDate='null', pubDate='1778515200000', pubDateStr='2026-05-12', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788926497576, creator='13701087609', updateTime=1788926796984, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304416787358049066, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304415531491152712, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304416787358049067, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304415531491152712, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=3281, endPage=3288, ext={EN=ArticleExt(id=1304415533613470552, articleId=1304415533345035094, tenantId=1146029695717560320, journalId=1302319053441957962, language=EN, title=A novel limonoid-type triterpene from Melia toosendan, columnId=null, journalTitle=Chinese Traditional and Herbal Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective To investigate the chemical constituents of limonoid-type triterpenes from the 95% ethanol extract of Melia toosendan and their antitumor activity. Methods The compounds were isolated and purified using various chromatographic techniques, including normal-pressure column chromatography, high-pressure column chromatography, and gel column chromatography. The isolated compounds were structurally characterized by modern spectroscopic techniques. Their antitumor activity was evaluated using the CCK-8 assay. Results Eight limonoid-type triterpenoids were isolated from the ethyl acetate extract of M. toosendan. Structural elucidation by spectroscopic techniques identified them as 15-oxotrichilinin (1), 11,15-dioxotrichilinin (2), 12-O-ethyl nimbolinin B (3), mufolinoid U (4), trichilinin (5), trichilinin D (6), trichilinin E (7), and trichilinin G (8). Activity evaluation results showed that all compounds exhibited varying degrees of inhibitory effects on four tumor cell lines. Conclusion Compound 1 is a new compound, named 15-oxotrichilinin. Antitumor activity results indicated that compounds 1—8 all possess antitumor activity to varying extents, with some compounds showing favorable activity against HepG2 cells., authors=DU Lin, WANG Qihui, FU Xiaohong, ZHANG Shuo, WANG Fang, YANG Min, authorsList=DU Lin, WANG Qihui, FU Xiaohong, ZHANG Shuo, WANG Fang, YANG Min, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1304415533533778775, articleId=1304415533345035094, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=川楝子中1个新的柠檬苦素型三萜化合物, columnId=1304140187169214944, journalTitle=中草药, columnName=化学成分, runingTitle=null, highlight=null, articleAbstract=目的 研究川楝子Melia toosendan 95%乙醇提取物中柠檬苦素类的化学成分及抗肿瘤活性。方法 采用常压柱色谱、高压柱色谱和凝胶柱色谱等多种分离技术进行分离纯化，并利用现代波谱技术对分离得到的化合物进行结构表征。同时通过CCK-8法评估其抗肿瘤活性。结果 从川楝子醋酸乙酯萃取部分共分离到8个柠檬苦素型三萜化合物，通过波谱技术分别鉴定为15-oxotrichilinin（1）、11,15-dioxotrichilinin（2）、12-O-ethyl nimbolinin B（3）、mufolinoid U（4）、trichilinin（5）、trichilinin D（6）、trichilinin E（7）、trichilinin G（8）。活性评价结果显示各化合物对4种肿瘤细胞均具有不同程度的抑制作用。结论 化合物1为新的化合物，命名为川楝子酮。抗肿瘤活性表明，化合物1～8均有不同程度的抗肿瘤活性，部分化合物显示对HepG2细胞有良好抑制活性。, authors=杜琳¹, 王琪慧¹, 傅小红¹, 张硕¹, 王芳¹, 杨敏¹, authorsList=杜琳, 王琪慧, 傅小红, 张硕, 王芳, 杨敏, authorCompany=1 成都师范学院, 化学与生命科学学院功能分子结构优化与应用四川省高校重点实验室, 四川 成都 611130, correspAuthors=杨敏, authorNote=杜琳: 杜琳(1981-),女,博士,副教授,研究方向为绿色化学。E-mail:517393653@qq.com, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=grHe+vtnFqA9vWSmCfN2sQ==, pdfFileSize=907405, pdfExtLink=null, richHtmlUrl=null, 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