Article(id=1304415031379128415, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304414997581427653, articleNumber=null, orderNo=null, doi=10.7501/j.issn.0253-2670.2026.08.029, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1761926400000, receivedDateStr=2025-11-01, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788926378339, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788926378339, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788926378339, creator=13701087609, updateTime=1788926378339, updator=13701087609, issue=Issue{id=1304414997581427653, tenantId=1146029695717560320, journalId=1302319053441957962, year='2026', volume='57', issue='8', pageStart='2877', pageEnd='3260', issueExtLink='null', onlineDate='null', pubDate='1777305600000', pubDateStr='2026-04-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788926370282, creator='13701087609', updateTime=1788926758667, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304416626649096991, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304414997581427653, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304416626649096992, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304414997581427653, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=3189, endPage=3195, ext={EN=ArticleExt(id=1304415031706284129, articleId=1304415031379128415, tenantId=1146029695717560320, journalId=1302319053441957962, language=EN, title=Research progress on treatment of prostate cancer with traditional Chinese medicine guided by “Chuzhuo Peiben” theory, columnId=null, journalTitle=Chinese Traditional and Herbal Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=“Chuzhuo Peiben” theory, proposed by nationally renowned Chinese medicine expert Professor Jia Yingjie, plays an important role in guiding the treatment of prostate cancer with traditional Chinese medicine. This article reviews the theory from the perspectives of theoretical interpretation, evidence integration, and paradigm construction. It systematically elucidates the dynamic pathogenesis model of “deficiency of the primordial foundation-coagulation of cancerous turbidity” and demonstrates the core logic of the strategy “tonifying the spleen surpasses tonifying the kidney” in circumventing androgen-related risks and remodeling the tumor microenvironment. In terms of clinical practice, it analyzes the staging-based dynamic treatment system centered around the “Jianpi Lishi Huayu Formula” and evaluates its synergistic value in combined therapy for “enhancing efficacy and reducing toxicity” and “delaying drug resistance.” At the mechanistic level, it integrates multidisciplinary evidence to construct a stereoscopic action network that spans from “multi-target synergistic prediction” to “core pathway experimental validation” and further to “tumor immune microenvironment remodeling,” thereby clarifying the biological basis of integrative intervention. The review also summarizes three core paradigmatic values of TCM intervention. In response to current research challenges, it proposes strategies such as designing prospective platform trials, applying multi-omics technologies, and constructing TCM-specific core outcome sets to promote the development of this field toward evidence-based and precision medicine paradigms., authors=MOU Ruiyu, MA Mingze, YANG Peiying, ZHU Jinli, JIA Yingjie, authorsList=MOU Ruiyu, MA Mingze, YANG Peiying, ZHU Jinli, JIA Yingjie, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1304415031634980960, articleId=1304415031379128415, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=“黜浊培本”理论指导中医药治疗前列腺癌的研究进展, columnId=1304140194685415572, journalTitle=中草药, columnName=综述, runingTitle=null, highlight=null, articleAbstract=“黜浊培本”理论由全国名中医贾英杰教授提出，在指导中医药治疗前列腺癌中有重要作用。围绕该理论，从理论阐释、证据整合与范式构建等方面进行梳理，系统阐释了“本元亏虚-癌浊胶结”动态病机模型，并论证了“补肾不如补脾”战略在规避雄激素风险与重塑肿瘤微环境方面的核心逻辑。临床实践方面，深度解析了以“健脾利湿化瘀方”为轴心的分期动态治疗体系，量化评估了其在联合治疗中“增效减毒”与“延迟耐药”的协同价值。机制研究层面，整合多学科证据，构建了从“多靶点协同预测”到“核心通路实验验证”，再到“肿瘤免疫微环境重塑”的立体作用网络，阐明了整合干预的生物学基础。进一步凝练了中医药干预的三大核心范式价值，并针对当前研究挑战，提出通过设计前瞻性平台试验、运用多组学技术、构建中医特色结局评价体系等策略，驱动该领域向循证与精准医学范式转型。, authors=牟睿宇^1,2,3, 马铭泽^1,2,3, 杨佩颖^1,2,3, 朱津丽^1,2,3, 贾英杰^1,2,3, authorsList=牟睿宇, 马铭泽, 杨佩颖, 朱津丽, 贾英杰, authorCompany=1 天津中医药大学第一附属医院, 天津 300381;
2 中医国家临床医学研究中心, 天津 300381;
3 天津市中医肿瘤研究所, 天津 300381, correspAuthors=贾英杰, authorNote=牟睿宇: 牟睿宇,男,博士,主治医师,从事中医药防治前列腺癌的临床与基础转化研究。E-mail:mouruiyu@163.com, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=DrlJTXcvSSAUIASQRaElhw==, pdfFileSize=822650, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=天津中医药大学第一附属医院科研基金项目 (院XB2024007); 天津市卫健委项目 (2025050))}, authors=[Author(id=1307431842722898651, tenantId=1146029695717560320, journalId=null, articleId=1304415031379128415, orderNo=null, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=null, authorType=null, ext={EN=AuthorExt(id=null, tenantId=null, journalId=1302319053441957962, articleId=1304415031379128415, authorId=1307431842722898651, language=EN, stringName=MOU Ruiyu, MA Mingze, YANG Peiying, ZHU Jinli, JIA Yingjie, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=null, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null), CN=AuthorExt(id=null, tenantId=null, journalId=1302319053441957962, articleId=1304415031379128415, authorId=1307431842722898651, language=CN, stringName=牟睿宇, 马铭泽, 杨佩颖, 朱津丽, 贾英杰, firstName=null, middleName=null, lastName=null, prefix=null, suffix=null, authorComment=null, nameInitials=null, affiliation=null, department=null, xref=null, address=null, bio=null, bioImg=null, bioContent=null, aboutCorrespAuthor=null)}, companyList=null)], keywords=[Keyword(id=1304415031848890466, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415031379128415, language=CN, orderNo=1, keyword=前列腺癌), Keyword(id=1304415031932776547, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415031379128415, language=CN, orderNo=2, keyword=黜浊培本), Keyword(id=1304415032016662628, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415031379128415, language=CN, orderNo=3, keyword=健脾利湿化瘀方), Keyword(id=1304415032100548709, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415031379128415, language=CN, orderNo=4, keyword=从脾论治), Keyword(id=1304415032184434790, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415031379128415, language=CN, orderNo=5, keyword=整合医学), Keyword(id=1304415032289292391, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415031379128415, language=EN, orderNo=1, keyword=prostate cancer), Keyword(id=1304415032356401256, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415031379128415, language=EN, orderNo=2, keyword=Chuzhuo Peiben), Keyword(id=1304415032427704425, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415031379128415, language=EN, orderNo=3, keyword=Jianpi Lishi Huayu Formula), Keyword(id=1304415032511590506, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415031379128415, language=EN, orderNo=4, keyword=treatment based on spleen theory), Keyword(id=1304415032578699371, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415031379128415, language=EN, orderNo=5, keyword=integrative medicine)], refs=null, funds=null, companyList=null, figs=null, attaches=null, journal=Journal(id=1302309778002903112, delFlag=0, nameCn=中草药, nameEn=Chinese Traditional and Herbal Drugs, nameHistory1=null, nameHistory2=null, issn=0253-2670, eissn=null, cn=12-1108/R, coden=null, periodic=3, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=cGpSKCP11AF8PAOcTXYWfg==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Traditional and Herbal Drugs, journalRemark=null, publicationField=null, createdTime=1788424446827, updatedTime=1788949289390, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=cGpSKCP11AF8PAOcTXYWfg==, picEn=Xw//kxUC3ON4eHxev0QLhQ==, jcr=null, cjcr=null, exts=[JournalExt(id=1304511127375863983, language=CN, name=中草药, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949289411, updatedTime=1788949289411, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://www.tiprpress.com/zcy/author/login, submissionEditorUrl=https://www.tiprpress.com/zcy/editor/login, submissionReviewUrl=https://www.tiprpress.com/zcy/reviewer/login, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1304511127442972848, language=EN, name=Chinese Traditional and Herbal Drugs, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949289427, updatedTime=1788949289427, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://www.tiprpress.com/zcy/author/login, submissionEditorUrl=https://www.tiprpress.com/zcy/editor/login, submissionReviewUrl=https://www.tiprpress.com/zcy/reviewer/login, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1302319053441957962, websiteList=[Website(id=1302319176408912052, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1302319053441957962, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zcy/CN, language=CN, createTime=1788426687576, createBy=18614031015, updateTime=1788427346252, updateBy=18614031015, name=中草药-中文, tplId=1146099689490845704, title=中草药, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1302322043651904087, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=articleTextType, value=kx, createTime=1788427371180, updateTime=1788427371180, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043593183828, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=banner, value=null, createTime=1788427371166, updateTime=1788427371166, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043672875610, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=grayFlag, value=0, createTime=1788427371185, updateTime=1788427371185, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043584795219, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=logo, value=https://castjournals.cast.org.cn/joweb/zcy/CN/file/pic?fileId=uiD1gpiRqR++OLOz4iKzDg==, createTime=1788427371164, updateTime=1788427371164, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043689652828, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=minRunFlag, value=0, createTime=1788427371189, updateTime=1788427371189, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043643515478, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zcy/CN/file/pic, createTime=1788427371178, updateTime=1788427371178, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043681264219, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=silenceFlag, value=0, createTime=1788427371187, updateTime=1788427371187, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043601572437, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1788427371168, updateTime=1788427371168, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043660292696, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=themeColor, value=null, createTime=1788427371182, updateTime=1788427371182, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043668681305, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=themeStyle, value=null, createTime=1788427371184, updateTime=1788427371184, creator=18614031015, updator=18614031015)]), Website(id=1302319176715096246, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1302319053441957962, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zcy/EN, language=EN, createTime=1788426687649, createBy=18614031015, updateTime=1788427341161, updateBy=18614031015, name=中草药-英文, tplId=1146101810881728533, title=Chinese Traditional and Herbal Drugs, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1302322015206134340, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=articleTextType, value=kx, createTime=1788427364398, updateTime=1788427364398, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015185162817, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=banner, value=null, createTime=1788427364393, updateTime=1788427364393, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015227105863, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=grayFlag, value=0, createTime=1788427364403, updateTime=1788427364403, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015176774208, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=logo, value=https://castjournals.cast.org.cn/joweb/zcy/EN/file/pic?fileId=uiD1gpiRqR++OLOz4iKzDg==, createTime=1788427364391, updateTime=1788427364391, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015239688777, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=minRunFlag, value=0, createTime=1788427364406, updateTime=1788427364406, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015201940035, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zcy/EN/file/pic, createTime=1788427364397, updateTime=1788427364397, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015235494472, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=silenceFlag, value=0, createTime=1788427364405, updateTime=1788427364405, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015193551426, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1788427364395, updateTime=1788427364395, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015214522949, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=themeColor, value=null, createTime=1788427364400, updateTime=1788427364400, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015218717254, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=themeStyle, value=null, createTime=1788427364401, updateTime=1788427364401, creator=18614031015, updator=18614031015)])], journalTitle=中草药, weixinUrl=null, journalUrl=https://www.tiprpress.com/zcy, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Traditional and Herbal Drugs, journalPhotoCn=cGpSKCP11AF8PAOcTXYWfg==, journalPhotoEn=Xw//kxUC3ON4eHxev0QLhQ==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zcy/CN/10.7501/j.issn.0253-2670.2026.08.029, detailUrlEn=https://castjournals.cast.org.cn/joweb/zcy/EN/10.7501/j.issn.0253-2670.2026.08.029, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zcy/CN/PDF/10.7501/j.issn.0253-2670.2026.08.029, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zcy/EN/PDF/10.7501/j.issn.0253-2670.2026.08.029, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1788926378339, fullTextJson=null, articleText=null, reference=Nguyen P L, Alibhai S M H, Basaria S, et al. Adverse effects of androgen deprivation therapy and strategies to mitigate them[J]. Eur Urol, 2015, 67(5):825-836.
Kirby M, Hirst C, Crawford E D. Characterising the castration-resistant prostate cancer population:A systematic review[J]. Int J Clin Pract, 2011, 65(11):1180-1192.
Sartor O, de Bono J S. Metastatic prostate cancer[J]. N Engl J Med, 2018, 378(7):645-657.
Schaeffer E M, Srinivas S, Adra N, et al. Prostate Cancer, Version 4. 2023, NCCN Clinical Practice Guidelines in Oncology[J]. J Natl Compr Canc Netw, 2023, 21(10):1067-1096.
贾英杰, 李小江, 杨佩颖, 等."黜浊培本"防治恶性肿瘤理论探析[J]. 中医杂志, 2021, 62(15):1277-1281.
孙彬栩, 李小江, 蔡启亮, 等."健脾利湿化瘀方"联合治疗去势抵抗性前列腺癌的临床研究[J]. 天津中医药, 2020, 37(8):885-891.
牟睿宇, 李小江, 廖洋, 等. 基于"黜浊培本"理论从中焦论治前列腺癌[J]. 天津中医药, 2022, 39(11):1388-1393.
牛潇菲, 邬明歆, 牟睿宇, 等. 贾英杰"黜浊培本"论治前列腺癌经验[J]. 陕西中医, 2022, 43(1):111-113.
王金秀, 李小江, 陈军, 等. 贾英杰论前列腺癌的中医病机与治疗[J]. 新中医, 2014, 46(4):20-23.
贾英杰, 陈军, 李小江, 等. 前列腺癌中医证候研究的文献分析[J]. 辽宁中医杂志, 2014, 41(9):1850-1852.
苏剑飞, 牟睿宇, 刘筱迪, 等. 贾英杰教授从"脾"论治前列腺癌[J]. 陕西中医, 2023, 44(5):636-639.
张瑶, 李小江, 贾英杰. 中医"健脾利湿化瘀法"在前列腺癌治疗中的运用[J]. 天津中医药, 2021, 38(3):317-321.
孙彬栩, 宋彦奇, 李小江, 等. 贾英杰教授从"浊毒致癌"辨治前列腺癌经验荟萃[J]. 天津中医药, 2022, 39(2):161-165.
陆莹, 牟睿宇, 宋博, 等. 贾英杰活用"黜浊培本"理论分期治疗前列腺癌经验[J]. 山东中医杂志, 2023, 42(7):747-750.
Hanahan D. Hallmarks of cancer:New dimensions[J]. Cancer Discov, 2022, 12(1):31-46.
牟睿宇, 李小江. 贾英杰治疗晚期前列腺癌经验[J]. 中医杂志, 2020, 61(15):1314-1317.
贾英杰, 李小江, 杨佩颖, 等. 中医外治法治疗前列腺癌的研究进展[J]. 中医肿瘤学杂志, 2021, 3(5):83-87.
Hirata H, Hinoda Y, Kikuno N, et al. Bcl2-938C/a polymorphism carries increased risk of biochemical recurrence after radical prostatectomy[J]. J Urol, 2009, 181(4):1907-1912.
马铭泽, 贾彩燕, 牟睿宇, 等. 中医补法治疗前列腺癌研究进展[J]. 天津中医药, 2025, 42(6):812-816.
王娜, 王雪瑞, 孟源, 等."黜浊培本"辨治前列腺癌的用药规律及机制研究[J]. 四川中医, 2025, 43(11):167-175.
邓仁芬, 姚杨, 李小江, 等. 贾英杰"守方微调"治疗前列腺癌经验[J]. 中医杂志, 2019, 60(20):1724-1727.
李小江, 冯梦晗, 牟睿宇, 等."健脾利湿化瘀法"治疗中晚期前列腺癌内分泌治疗后部分雄激素缺乏综合征的临床观察[J]. 中草药, 2020, 51(21):5559-5565.
陆莹, 李小江. 贾英杰教授 "黜浊培本法"治疗前列腺癌骨转移经验[J]. 河北中医, 2021, 43(1):14-17.
赵林林, 贾英杰, 李小江, 等. 贾英杰教授治疗前列腺癌经验举隅[J]. 天津中医药, 2021, 38(1):34-36.
陆莹, 牟睿宇, 宋博, 等. 贾英杰教授运用"黜浊培本"法治疗前列腺癌部分雄激素缺乏综合征经验[J]. 天津中医药, 2022, 39(8):965-969.
刘金明, 孙彬栩. 贾英杰从三焦论治前列腺癌内分泌治疗后潮热经验[J]. 现代中医临床, 2025, 32(1):112-116.
肖贤. 基于ceRNA网络探究健脾利湿化瘀方联合治疗调控高危局限性前列腺癌临床及分子机制研究[D]. 天津:天津中医药大学, 2023.
王晓群, 贾英杰, 李小江. 贾英杰治疗前列腺癌验案1则[J]. 湖南中医杂志, 2013, 29(7):95-96.
牟睿宇, 李小江, 刘昭, 等. 中西医结合治疗去势抵抗性前列腺癌近期临床疗效分析[J]. 中华中医药杂志, 2022, 37(6):3590-3594.
牟睿宇, 刘昭, 王亮, 等. 去势抵抗性前列腺癌预后生物标志物研究进展[J]. 医学综述, 2021, 27(17):3401-3406.
李文杰, 牟睿宇, 李小江. 寡转移性前列腺癌治疗进展[J]. 中华男科学杂志, 2020, 26(9):832-837.
张瑶, 陈军, 李小江, 等. 中药提取成分抑制人前列腺癌PC3细胞研究进展[J]. 时珍国医国药, 2015, 26(2):446-448.
牟睿宇, 李小江, 郭姗琦, 等."健脾利湿化瘀方"联合治疗激素敏感性前列腺癌的真实世界研究[J]. 中国肿瘤临床, 2023, 50(11):561-566.
张小青, 贾英杰, 王林欢, 等. 基于"黜浊培本"理论探讨健脾利湿化瘀法联合醋酸阿比特龙治疗转移性去势抵抗性前列腺癌的临床疗效和安全性[J]. 中草药, 2022, 53(20):6536-6543.
程闻. "健脾利湿化瘀方"治疗转移性激素敏感性前列腺癌优势人群特征分析及预测模型的建立[D]. 天津:天津中医药大学, 2024.
韩增风. 高危局限性前列腺癌中医证型相关性研究及健脾利湿化瘀方联合治疗的临床疗效观察[D]. 天津:天津中医药大学, 2024.
宋彦奇, 孙彬栩, 韩增风, 等. 局部高危前列腺癌免疫组织化学指标与中医证型的相关性研究[J]. 中国肿瘤临床, 2022, 49(22):1166-1169.
宋彦奇. 局部高危前列腺癌中医证型与分子分型及复发分层研究[D]. 天津:天津中医药大学, 2021.
徐竞一. 前列腺癌患者中医体质分布特点与其危险因素的相关性分析[D]. 天津:天津中医药大学, 2021.
韩增风, 王超然, 肖贤, 等. 以"黜浊治中"理论探讨针药并治前列腺癌术后尿失禁[J]. 天津中医药, 2023, 40(8):993-996.
王超然, 李小江, 杨佩颖, 等. 针灸治疗前列腺癌术后尿失禁随机对照试验的文献报告质量评价[J]. 中医肿瘤学杂志, 2021, 3(4):82-87.
陆莹, 刘筱迪, 牛潇菲, 等. 中医对减轻前列腺癌内分泌治疗相关潮热的研究进展[J]. 空军军医大学学报, 2022, 43(2):230-234.
张瑶, 贾英杰, 李小江, 等."健脾利湿化瘀方"治疗前列腺癌在抑制微血管生成方面的作用与机制研究[Z]. 天津:天津中医药大学第一附属医院, 2022.
李家合. 基于网络药理学探讨"健脾利湿化瘀方"治疗前列腺癌的分子机理[D]. 天津:天津中医药大学, 2020.
牟睿宇, 廖洋, 贾春鑫, 等. 王不留行环肽B逆转前列腺癌C4-2细胞激素非依赖性生长及作用机制[J]. 中草药, 2024, 55(17):5898-5904.
牟睿宇. 姜黄素调控前列腺癌细胞生物学行为及作用机制研究[D]. 天津:天津中医药大学, 2021.
王林欢. 基于"黜浊培本"理论探讨"健脾利湿化瘀法"联合醋酸阿比特龙治疗转移性去势抵抗性前列腺癌的临床疗效[D]. 天津:天津中医药大学, 2021.
史梦瑶, Nuttapong W, 王雪妮, 等. HN Saponin F通过雄激素受体抑制雄激素依赖的前列腺癌细胞LNCaP增殖[J]. 中南药学, 2019, 17(10):1591-1595.
孙彬栩, 贾英杰, 李小江, 等. 基于AR信号通路初探大黄、姜黄、王不留行药物组成逆转前列腺癌激素非依赖的作用及机制研究[Z]. 天津:天津中医药大学第一附属医院, 2022.
陈璐瑶. 基于Akt/mTOR/SREBPs通路探讨ECG抑制前列腺癌细胞脂肪酸合成的作用机制[D]. 天津:天津中医药大学, 2021.
张瑶, 许月梅, 李家合, 等. 基于PI3K/Akt/eNOS信号通路探讨健脾利湿化瘀方抑制前列腺癌血管生成的实验研究[J]. 天津中医药, 2021, 38(4):522-527.
孙彬栩, 蔡启亮, 李小江, 等. 基于IGF/MMP信号通路研究健脾利湿化瘀方有效拆方对前列腺癌细胞侵袭、迁移的影响[J]. 天津中医药, 2020, 37(4):450-456.
张小青, 李禄, 王为民, 等. 六味地黄汤合三圣散联合唑来膦酸治疗前列腺癌骨转移的作用及机制研究[J]. 中草药, 2022, 53(23):7461-7466.
贾春鑫."健脾利湿化瘀方"调节前列腺癌免疫微环境机制及疗效分析[D]. 天津:天津中医药大学, 2024.
廖洋."健脾利湿化瘀方"对转移性激素敏感性前列腺癌免疫功能和疾病进展的影响[D]. 天津:天津中医药大学, 2024.
李小江, 牟睿宇, 邬明歆, 等. 中医药治疗去势抵抗性前列腺癌的研究进展[J]. 中草药, 2019, 50(4):1007-1011.
李文杰, 贾英杰, 牟睿宇, 等. 贾英杰教授应用"圣愈汤"治疗晚期前列腺癌经验总结[J]. 天津中医药, 2020, 37(11):1241-1244.
贾英杰, 李小江, 李超, 等. 益气解毒祛瘀方联合内分泌治疗晚期前列腺癌临床疗效分析[J]. 中国中西医结合杂志, 2013, 33(4):448-451.
陆莹."健脾利湿化瘀方"联合"最大雄激素阻断"治疗激素敏感性前列腺癌的临床研究及ctDNA初探[D]. 天津:天津中医药大学, 2022.
冯梦晗, 李小江. AR信号通路与自噬的相关性在前列腺癌治疗中的应用[J]. 转化医学杂志, 2019, 8(2):123-126.
牟睿宇, 李小江. 贾英杰运用"截断疗法"治疗前列腺癌[J]. 辽宁中医杂志, 2017, 44(11):2296-2298.
张瑶, 李小江, 杨佩颖, 等. 中医药联合内分泌疗法治疗前列腺癌的研究进展[J]. 时珍国医国药, 2017, 28(4):952-954.
田汇川. 中医药治疗前列腺癌临床研究核心结局指标集的构建[D]. 天津:天津中医药大学, 2024.
牛潇菲, 张畅, 李小江. 基于CiteSpace的中医药治疗前列腺癌可视化分析[J]. 中医药导报, 2021, 27(8):160-164.
张瑶, 贾英杰. 基于脏腑辨证的前列腺癌中医治疗进展概述[J]. 河北中医, 2017, 39(2):308-312.
思志强, 张莹, 孙彬栩, 等. 放射性125I粒子植入治疗前列腺癌的研究进展[J]. 中国肿瘤外科杂志, 2020, 12(1):74-78.
程晓玉, 贾英杰, 陈军, 等. 激素非依赖性前列腺癌治疗近况[J]. 辽宁中医药大学学报, 2014, 16(10):145-148.
孙一予, 贾英杰, 陈军, 等. 中医药治疗前列腺癌机制研究简况[J]. 实用中医内科杂志, 2013, 27(18):90-93.
Chang Y L, Ou Q L, Zhou X H, et al. Jianpi Jiedu Decoction suppresses colorectal cancer growth by inhibiting M2 polarization of TAMs through the tryptophan metabolism-AhR pathway[J]. Int Immunopharmacol, 2024, 138:112610.
Hanahan D, Weinberg R A. Hallmarks of cancer:The next generation[J]. Cell, 2011, 144(5):646-674.)