中草药

中药抑制铁死亡治疗脓毒症相关急性肺损伤的研究进展

PDF下载

中草药 | 综述 2026,57(7): 2799-2808

收起

中草药 |综述 2026 , 57 (7) : 2799 -2808

中药抑制铁死亡治疗脓毒症相关急性肺损伤的研究进展

全屏

范国旗^1,2,3, 陈琪^1,2,3, 王芳芳^1,3, 刘丽伟^1,3, 魏征⁴, 李朵璐¹, 李晓静^1,3, 冯雪琼^1,3, 左莉华^1,3, 孙志^1,3

作者信息

通讯作者:

左莉华

作者简介:

范国旗: 范国旗,硕士研究生,研究方向为中医药治疗脓毒症。E-mail:18737956507@163.com

Research progress on traditional Chinese medicine in treatment of sepsis-associated acute lung injury by inhibiting ferroptosis

FAN Guoqi, CHEN Qi, WANG Fangfang, LIU Liwei, WEI Zheng, LI Duolu, LI Xiaojing, FENG Xueqiong, ZUO Lihua, SUN Zhi

Affiliations

doi: 10.7501/j.issn.0253-2670.2026.07.029

文章导航

摘要

收起

脓毒症相关急性肺损伤（sepsis-associated acute lung injury，SA-ALI）是临床常见的危重并发症，当前治疗手段有限，严重威胁患者生命健康。中药具有多靶点、多途径干预和不良反应少等优势，在SA-ALI防治中展现出一定潜力。铁死亡是一种铁依赖性的新型程序性细胞死亡，其机制与铁代谢失衡、脂质过氧化失控及抗氧化防御能力受损密切相关，在SA-ALI的病理进程中发挥重要作用。现有研究表明，姜黄素、银杏叶提取物及血必净注射液等可通过激活抗氧化信号通路、促进谷胱甘肽合成、调节铁离子代谢稳态等途径抑制铁死亡，进而减轻肺组织损伤。通过阐述铁死亡与SA-ALI的关联，系统总结近年来中药靶向调控铁死亡干预SA-ALI的研究成果，为临床诊疗策略优化及创新药物开发提供理论支撑。

关键词

中药 / 铁死亡 / 脓毒症 / 急性肺损伤 / 姜黄素 / 银杏叶提取物

Abstract

收起

Sepsis-associated acute lung injury (SA-ALI) is a common and life-threatening complication in critically ill patients, for which current therapeutic options remain limited. Traditional Chinese medicine (TCM) exhibits multi-target and multi-pathway regulatory effects with relatively few adverse reactions, showing promising potential in the prevention and treatment of SA-ALI. Ferroptosis is an iron-dependent form of regulated cell death, driven by iron metabolism dysregulation, uncontrolled lipid peroxidation chain reaction, and impaired antioxidant defense systems, and it plays a pivotal role in the pathogenesis of SA-ALI. Emerging evidence indicates that TCM agents—such as curcumin, Ginkgo leaves extract, and Xuebijing Injection—can suppress ferroptosis by activating antioxidant signaling pathways, promoting glutathione synthesis, and restoring iron homeostasis, thereby alleviating pulmonary tissue damage. This article systematically reviews recent advances in TCM-mediated targeting of ferroptosis for SA-ALI, aiming to provide a theoretical foundation for optimizing clinical strategies and developing novel therapeutics.

Key words

traditional Chinese medicine / ferroptosis / sepsis / acute lung injury / curcumin / Ginkgo leaves extract

引用本文

范国旗, 陈琪, 王芳芳, 刘丽伟, 魏征, 李朵璐, 李晓静, 冯雪琼, 左莉华, 孙志. 中药抑制铁死亡治疗脓毒症相关急性肺损伤的研究进展. 中草药, 2026 , 57 (7) : 2799 -2808 . DOI: 10.7501/j.issn.0253-2670.2026.07.029

FAN Guoqi, CHEN Qi, WANG Fangfang, LIU Liwei, WEI Zheng, LI Duolu, LI Xiaojing, FENG Xueqiong, ZUO Lihua, SUN Zhi. Research progress on traditional Chinese medicine in treatment of sepsis-associated acute lung injury by inhibiting ferroptosis[J]. Chinese Traditional and Herbal Drugs, 2026 , 57 (7) : 2799 -2808 . DOI: 10.7501/j.issn.0253-2670.2026.07.029

基金

收起

国家自然科学基金面上项目 (82374018); 河南省“三个100”计划临床医学科学家培养专项 (HNCMS202432,HNCMS202411); 河南省中青年卫生健康科技创新人才培养“杰青项目” (JQRC2024013)

参考文献

收起

文献

收起

参考文献引证文献

排序方式：

曾仪晨,马雨雯,曾榆淞,等.四妙勇安汤加减化裁治疗脓毒症的研究进展及其应用开发思路与方法[J].中草药, 2025, 56(1):330-339.
宋宁,马培梁,杨娟,等.大黄素防治脓毒症肺损伤的研究进展[J].现代药物与临床, 2025, 40(3):807-810.
Liu Y, Chen L. Impact of interleukin 6 levels on acute lung injury risk and disease severity in critically ill sepsis patients[J]. World J Clin Cases, 2024, 12(23):5374-5381.
Martin-Loeches I, de Haro C, Dellinger R P, et al.Effectiveness of an inspiratory pressure-limited approach to mechanical ventilation in septic patients[J]. Eur Respir J, 2013, 41(1):157-164.
Qiao X Y, Yin J H, Zheng Z H, et al. Endothelial cell dynamics in sepsis-induced acute lung injury and acute respiratory distress syndrome:Pathogenesis and therapeutic implications[J]. Cell Commun Signal, 2024,22(1):241.
Jin Z, Li M Y, Tang L J, et al. Protective effect of Ulinastatin on acute lung injury in diabetic sepsis rats[J].Int Immunopharmacol, 2022, 108:108908.
Zhuo Y Z, Yang L, Li D H, et al. Syringaresinol resisted sepsis-induced acute lung injury by suppressing pyroptosis via the oestrogen receptor-β signalling pathway[J].Inflammation, 2022, 45(2):824-837.
Zhang J, Zheng Y P, Wang Y, et al. YAP1 alleviates sepsisinduced acute lung injury via inhibiting ferritinophagymediated ferroptosis[J]. Front Immunol, 2022, 13:884362.
Wang Y F, Zhao Z J, Xiao Z Y. The emerging roles of ferroptosis in pathophysiology and treatment of acute lung injury[J]. J Inflamm Res, 2023, 16:4073-4085.
Lin Z, Liu J, Long F, et al. The lipid flippase SLC47A1blocks metabolic vulnerability to ferroptosis[J]. Nat Commun, 2022, 13(1):7965.
Wong R S Y. Apoptosis in cancer:From pathogenesis to treatment[J]. J Exp Clin Cancer Res, 2011, 30(1):87.
Jiang M Y, Hu R L, Yu R X, et al. A narrative review of mechanisms of ferroptosis in cancer:New challenges and opportunities[J]. Ann Transl Med, 2021, 9(20):1599.
代国年,孙凯瑞,周雅馨,等.基于铁死亡的青蒿素衍生物多病靶向治疗研究进展[J].中草药, 2025, 56(17):6389-6403.
Yehia A, Melhuish Beaupre L M, Ho M C, et al.Ferroptosis as a potential molecular mechanism of bipolar disorder[J]. Transl Psychiatry, 2025, 15(1):205.
肖仟骏,崔春晖.铁死亡与内质网应激在溃疡性结肠炎病理机制中的研究进展[J].实用医学杂志, 2026,42(4):714-722.
Chen Y F, Li X T, Wang S Y, et al. Targeting iron metabolism and ferroptosis as novel therapeutic approaches in cardiovascular diseases[J]. Nutrients, 2023,15(3):591.
Silvestri L, Pettinato M, Furiosi V, et al. Managing the dual nature of iron to preserve health[J]. Int J Mol Sci, 2023,24(4):3995.
Vogt A S, Arsiwala T, Mohsen M, et al. On iron metabolism and its regulation[J]. Int J Mol Sci, 2021,22(9):4591.
Xu R, Wang W N, Zhang W L. Ferroptosis and the bidirectional regulatory factor p53[J]. Cell Death Discov,2023, 9(1):197.
Gawargi F I, Mishra P K. Regulation of cardiac ferroptosis in diabetic human heart failure:Uncovering molecular pathways and key targets[J]. Cell Death Discov, 2024,10(1):268.
Kotla N K, Dutta P, Parimi S, et al. The role of ferritin in health and disease:Recent advances and understandings[J]. Metabolites, 2022, 12(7):609.
Abe C, Miyazawa T, Miyazawa T. Current use of Fenton reaction in drugs and food[J]. Molecules, 2022, 27(17):5451.
Zhang G H, Lv S M, Zhong X, et al. Ferroptosis:A new antidepressant pharmacological mechanism[J]. Front Pharmacol, 2024, 14:1339057.
Li J, Cao F, Yin H L, et al. Ferroptosis:Past, present and future[J]. Cell Death Dis, 2020, 11(2):88.
Jiang X J, Stockwell B R, Conrad M. Ferroptosis:Mechanisms, biology and role in disease[J]. Nat Rev Mol Cell Biol, 2021, 22(4):266-282.
Endale H T, Tesfaye W, Mengstie T A. ROS induced lipid peroxidation and their role in ferroptosis[J]. Front Cell Dev Biol, 2023, 11:1226044.
Li Y B, Li X S, Li J. Ferroptosis in lung cancer:Dual role,multi-level regulation, and new therapeutic strategies[J].Front Oncol, 2024, 14:1360638.
Tang D L, Chen X, Kang R, et al. Ferroptosis:Molecular mechanisms and health implications[J]. Cell Res, 2021,31(2):107-125.
Li J L, Li L X, Zhang Z, et al. Ferroptosis:An important player in the inflammatory response in diabetic nephropathy[J]. Front Immunol, 2023, 14:1294317.
Deng P, Wu Y, Wan L, et al. Maresin1 alleviates ischemia reperfusion injury after lung transplantation by inhibiting ferroptosis via the PKA-hippo-YAP signaling pathway[J].Biomedicines, 2025, 13(7):1594.
Li S W, Zhang G X, Hu J K, et al. Ferroptosis at the nexus of metabolism and metabolic diseases[J]. Theranostics,2024, 14(15):5826-5852.
Mandal P K, Seiler A, Perisic T, et al. System Xc-and thioredoxin reductase 1 cooperatively rescue glutathione deficiency[J]. J Biol Chem, 2010, 285(29):22244-22253.
Orlowska K, Fling R R, Nault R, et al. Cystine/glutamate Xc-antiporter induction compensates for transsulfuration pathway repression by 2,3,7,8-tetrachlorodibenzo-pdioxin(TCDD)to ensure cysteine for hepatic glutathione biosynthesis[J]. Chem Res Toxicol, 2023, 36(6):900-915.
Seibt T M, Proneth B, Conrad M. Role of GPX4 in ferroptosis and its pharmacological implication[J]. Free Radic Biol Med, 2019, 133:144-152.
Liu L, Liu R, Liu Y, et al. Cystine-glutamate antiporter x CT as a therapeutic target for cancer[J]. Cell Biochem Funct, 2021, 39(2):174-179.
Li W T, Liang L, Liu S Y, et al. FSP1:A key regulator of ferroptosis[J]. Trends Mol Med, 2023, 29(9):753-764.
Doll S, Freitas F P, Shah R, et al. FSP1 is a glutathioneindependent ferroptosis suppressor[J]. Nature, 2019,575(7784):693-698.
Zeng F R, Chen X, Deng G T. The anti-ferroptotic role of FSP1:Current molecular mechanism and therapeutic approach[J]. Mol Biomed, 2022, 3(1):37.
Chen Y, Yi X, Huo B, et al. BRD4770 functions as a novel ferroptosis inhibitor to protect against aortic dissection[J].Pharmacol Res, 2022, 177:106122.
Stuehr D J, Santolini J, Wang Z Q, et al. Update on mechanism and catalytic regulation in the NO synthases[J]. J Biol Chem, 2004, 279(35):36167-36170.
Feng Y, Feng Y H, Gu L M, et al. Tetrahydrobiopterin metabolism attenuates ROS generation and radiosensitivity through LDHA S-nitrosylation:Novel insight into radiogenic lung injury[J]. Exp Mol Med, 2024,56(5):1107-1122.
Yin X F, Zhu G S, Wang Q, et al. Ferroptosis, a new insight into acute lung injury[J]. Front Pharmacol, 2021, 12:709538.
Xu Y F, Qu X T, Liang M H, et al. Focus on the role of calcium signaling in ferroptosis:A potential therapeutic strategy for sepsis-induced acute lung injury[J]. Front Med, 2024, 11:1457882.
Zou X, Liu C, Huang Z T, et al. Inhibition of STEAP1ameliorates inflammation and ferroptosis of acute lung injury caused by sepsis in LPS-induced human pulmonary microvascular endothelial cells[J]. Mol Biol Rep, 2023,50(7):5667-5674.
Zmijewski E, Lu S Z, Harrison-Findik D D. TLR4signaling and the inhibition of liver hepcidin expression by alcohol[J]. World J Gastroenterol, 2014, 20(34):12161-12170.
Billesbølle C B, Azumaya C M, Kretsch R C, et al.Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms[J]. Nature, 2020, 586(7831):807-811.
Chen H L, Wu S P, Lu R, et al. Pulmonary permeability assessed by fluorescent-labeled dextran instilled intranasally into mice with LPS-induced acute lung injury[J]. PLoS One, 2014, 9(7):e101925.
Tang X M, Liu J Q, Yao S, et al. Ferulic acid alleviates alveolar epithelial barrier dysfunction in sepsis-induced acute lung injury by activating the Nrf2/HO-1 pathway and inhibiting ferroptosis[J]. Pharm Biol, 2022, 60(1):2286-2294.
Zhou Z R, Xu B, Hu N, et al. Targeting the macrophageferroptosis crosstalk:A novel insight into tumor immunotherapy[J]. Front Biosci, 2022, 27(7):203.
Heil M, Land W G. Danger signals-damaged-self recognition across the tree of life[J]. Front Plant Sci, 2014,5:578.
Wang Y, Gu L F, Zhao X C, et al. TFR1 expression in induced sputum is associated with asthma severity[J].PeerJ, 2022, 10:e13474.
Wang X C, Garrick M D, Yang F, et al. TNF, IFN-gamma,and endotoxin increase expression of DMT1 in bronchial epithelial cells[J]. Am J Physiol Lung Cell Mol Physiol,2005, 289(1):L24-L33.
Chen Y, Fang Z M, Yi X, et al. The interaction between ferroptosis and inflammatory signaling pathways[J]. Cell Death Dis, 2023, 14(3):205.
Zhang L L, Tang R J, Yang Y J. The underlying pathological mechanism of ferroptosis in the development of cardiovascular disease[J]. Front Cardiovasc Med, 2022,9:964034.
Keshari R S, Jyoti A, Dubey M, et al. Cytokines induced neutrophil extracellular traps formation:Implication for the inflammatory disease condition[J]. PLoS One, 2012,7(10):e48111.
Ru Q, Li Y S, Chen L, et al. Iron homeostasis and ferroptosis in human diseases:Mechanisms and therapeutic prospects[J]. Signal Transduct Target Ther,2024, 9(1):271.
Zhang X L, Ma Y M, Lv G Q, et al. Ferroptosis as a therapeutic target for inflammation-related intestinal diseases[J]. Front Pharmacol, 2023, 14:1095366.
Li J X, Liu H, Shan Z T, et al. Molecular mechanisms and potential implications of ferroptosis, cuproptosis, and disulfidptosis in septic lung injury[J]. Front Med, 2025,12:1615264.
卢悦,张平平,王东强,等.急性肺损伤中医病因病机的探讨[J].中国中医急症, 2020, 29(2):280-282.
侯一楠,梁群,杨俊,等.中药注射剂和中药提取物治疗脓毒症急性肺损伤的研究进展[J].中国医院用药评价与分析, 2023, 23(1):120-122.
王西墨,余剑波,金胜威.脓毒症肺损伤中西医结合诊治专家共识[J].中国中西医结合外科杂志, 2020,26(3):400-408.
黄何尘,周绍荣,柳国斌,等.紫朱软膏治疗非缺血性糖尿病足溃疡的临床观察及其对铁死亡相关指标的影响[J].山东中医杂志, 2025, 44(10):1127-1136.
冯小霞,陈晨,邱静,等.黄连解毒汤调控FBXL5/IRP2改善Va D小鼠脑铁代谢紊乱、髓鞘损伤及激越攻击行为[J].中国实验方剂学杂志, 2024, 30(24):1-9.
刘泳君,魏佳明,林瑞芳,等.基于线粒体功能障碍-铁死亡路径探讨“脾病干心”理论在慢性心力衰竭中的科学内涵[J].实用心脑肺血管病杂志, 2025, 33(8):85-89.
林景楠.扶正解毒颗粒通过抑制铁死亡减轻急性肺损伤的作用机制研究[D].广州:广州中医药大学, 2024.
Li T, Tan Y, Ouyang S, et al. Resveratrol protects against myocardial ischemia-reperfusion injury via attenuating ferroptosis[J]. Gene, 2022, 808:145968.
吴瑶,宋囡,贾连群,等.化瘀祛痰方对载脂蛋白E基因敲除小鼠肝脏脂质过氧化及p53、GPX4、x CT表达的影响[J].中医杂志, 2020, 61(18):1633-1638.
季晗舒,宋纯东,王旭,等.益气养阴活血方对糖尿病肾病大鼠肾功能及SIRT3/SOD2/GPX4通路、铁死亡的影响[J].郑州大学学报:医学版, 2025, 60(4):488-492.
张志炜,贾旭林.杜鹃素对脓毒症小鼠急性肺损伤的保护性机制研究[J].西部医学, 2025, 37(6):827-832.
Chen K D, Lu S P, Shi K, et al. Hyperoside attenuates sepsis-induced acute lung injury by Nrf2 activation and ferroptosis inhibition[J]. Int Immunopharmacol, 2025,145:113734.
Zhang H, Wang Y, Wang S H, et al. Tangeretin alleviates sepsis-induced acute lung injury by inhibiting ferroptosis of macrophage via Nrf2 signaling pathway[J]. Chin Med,2025, 20(1):11.
Abdelmawgood I A, Mohamed A S, Mahana N A, et al.Chrysin-loaded PLGA nanoparticle attenuates ferroptosis in lipopolysaccharide-induced indirect acute lung injury by upregulating Nrf2-dependent antioxidant responses[J].Respir Physiol Neurobiol, 2025, 336:104451.
Lu J, Li A M, Feng Q Y. Isoginkgetin inhibits macrophage activation and ferroptosis of lung epithelial cells under lipopolysaccharide-induced immunological stress via HOXA5-dependent inhibition of the TLR4/NF-κΒsignaling pathway[J]. Toxicol Appl Pharmacol, 2025, 502:117413.
Xu B Y, Wang H D, Chen Z. Puerarin inhibits ferroptosis and inflammation of lung injury caused by sepsis in LPS induced lung epithelial cells[J]. Front Pediatr, 2021, 9:706327.
Zhang Y, Wu W H, An P, et al. Kaempferol inhibits ferroptosis in lung epithelial cells in LPS-induced acute lung injury via m5C methylation of TFRC[J]. Biol Pharm Bull, 2025, 48(9):1343-1350.
王俊梅,任春秀,金玲玲,等.甘草酸调控PRDX6表达与铁死亡减轻小鼠脓毒症急性肺损伤[J].中国细胞生物学学报, 2025, 47(8):1844-1852.
He S S, Ye H R, Wang Q, et al. Ginsenoside Rb1 targets to HO-1 to improve sepsis by inhibiting ferroptosis[J]. Free Radic Biol Med, 2025, 226:13-28.
Bu Y, Li Z X, Wang C, et al. Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury[J]. Front Pharmacol, 2025, 16:1590797.
Song L J, Tao Y Y, Lu G Y, et al. Saikosaponin D ameliorates sepsis-induced acute lung injury by maintaining alveolar epithelial barrier integrity and inhibiting ferroptosis via Nrf2/HO-1 pathway[J]. Inhal Toxicol, 2025, 37(4):195-207.
宋迪,李春华.绿原酸调控铁死亡缓解大鼠急性肺损伤[J].解剖科学进展, 2025, 31(5):699-702.
Zeng T, Zhou Y, Zheng J W, et al. Rosmarinic acid alleviates septic acute respiratory distress syndrome in mice by suppressing the bronchial epithelial RASmediated ferroptosis[J]. Int Immunopharmacol, 2024,135:112304.
Li Y C, Huang L T, Li J L, et al. Targeting TLR4 and regulating the Keap1/Nrf2 pathway with andrographolide to suppress inflammation and ferroptosis in LPS-induced acute lung injury[J]. Chin J Nat Med, 2024, 22(10):914-928.
石俊.石杉碱甲对脂多糖诱导急性肺损伤的保护作用及机制研究[D].广州:华南理工大学, 2024.
Chen K, Meng Z, Min J, et al. Curcumin alleviates septic lung injury in mice by inhibiting TXNIP/TRX-1/GPX4-mediated ferroptosis[J]. J South Med Univ, 2024, 44(9):1805-1813.
陈凯,孟兆菲,闵静婷,等.姜黄素通过抑制TXNIP/TRX-1/GPX4通路介导的铁死亡减轻脓毒症小鼠肺损伤[J].南方医科大学学报, 2024, 44(9):1805-1813.
王磊,蒯鑫,李青松,等.姜黄素抑制GPX4介导的铁死亡减轻大鼠脓毒症急性肺损伤[J].中国免疫学杂志, 2024, 40(10):2116-2120.
Zhen L L, Hou M T, Wang S B. Salidroside attenuates sepsis-induced acute lung injury by inhibiting ferroptosisdependent pathway[J]. Korean J Physiol Pharmacol,2024, 28(6):549-558.
李政宁.银杏叶提取物抑制STAT3通路活化对ARDS保护作用的机制研究[D].南宁:广西医科大学, 2022.
黄迪.银杏叶提取物抑制RIOK3-铁蛋白自噬轴改善脓毒症肺上皮细胞损伤机制及血瘀证特征研究[D].济南:山东中医药大学, 2024.
Zou F M, Zou J, Du Q Z, et al. XueBiJing Injection improves the symptoms of sepsis-induced acute lung injury by mitigating oxidative stress and ferroptosis[J]. J Ethnopharmacol, 2025, 337(Pt1):118732.
Li Z X, Yu Y J, Bu Y, et al. QiShenYiQi Pills preserve endothelial barrier integrity to mitigate sepsis-induced acute lung injury by inhibiting ferroptosis[J]. J Ethnopharmacol, 2024, 322:117610.
冯宇博,陈好,张相安.黄连解毒汤现代临床应用和作用机制研究进展[J].辽宁中医药大学学报, 2025,27(6):201-207.
龙敏,刘克琴,岳煜,等.黄连解毒汤调控Nrf2/SLC7A11/GPX4信号通路改善大鼠脓毒症急性肺损伤[J].中国实验方剂学杂志, 2025, 31(23):12-20.
覃玉芳.清瘟败毒饮加减联合奥司他韦治疗甲型流感儿童气营两燔证疗效观察[J].中国处方药, 2024,22(9):152-155.
武玉琳,王翠菡,崔亚萌,等.清瘟败毒饮对脓毒症肺损伤大鼠的治疗作用及对铁死亡的影响[J].环球中医药, 2024, 17(5):801-808.
马红双,郭瑞,李勇锋.血必净注射液治疗脓毒症合并急性肺损伤患者的临床观察[J].深圳中西医结合杂志, 2023, 33(21):31-34.
丁伟超,陈娟,叶英,等.血必净注射液治疗脓毒症相关急性呼吸窘迫综合征肺热血瘀证患者的临床疗效[J].中草药, 2024, 55(19):6645-6654.

2026年第57卷第7期

PDF下载

引用本文

BibTeX

文章信息

doi: 10.7501/j.issn.0253-2670.2026.07.029

接收时间：2025-11-19
首发时间：2026-09-09

补充材料

相关文章

文章信息

作者

出版历史

收稿日期：2025-11-19

基金

作者信息

参考文献

分享链接

https://castjournals.cast.org.cn/joweb/zcy/CN/10.7501/j.issn.0253-2670.2026.07.029

分享至

全文二维码

扫描看全文

引用本文

BibTeX

本文的引用情况

2种不同金属材料的力学参数

科 Family	属数 Number of genus	种数 Number of species	占总种数比例 Percentage of total species (%)	属 Genus	种数 Number of species	占总种数比例 Percentage of total species (%)
鹅膏菌科Amanitaceae	2	11	5.26	鹅膏菌属 Amanita	10	4.78
小菇科 Mycenaceae	2	12	5.74	丝盖伞属 Inocybe	5	2.39
多孔菌科 Polyporaceae	8	14	6.70	蜡蘑属 Laccaria	5	2.39
红菇科 Russulaceae	3	23	11.00	小皮伞属 Marasmius	6	2.87
				小菇属 Mycena	11	5.26
				光柄菇属 Pluteus	5	2.39
				红菇属 Russula	17	8.13
				栓菌属 Trametes	5	2.39

关闭全屏

BibTeX
EndNote
RefWorks
TxT