Article(id=1304406865513836599, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304406828071281069, articleNumber=null, orderNo=null, doi=10.7501/j.issn.0253-2670.2026.02.008, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1756137600000, receivedDateStr=2025-08-26, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788924431446, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788924431446, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788924431446, creator=13701087609, updateTime=1788924431446, updator=13701087609, issue=Issue{id=1304406828071281069, tenantId=1146029695717560320, journalId=1302319053441957962, year='2026', volume='57', issue='2', pageStart='393', pageEnd='788', issueExtLink='null', onlineDate='null', pubDate='1769529600000', pubDateStr='2026-01-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788924422518, creator='13701087609', updateTime=1788924652596, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304407793138688830, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304406828071281069, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304407793138688831, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304406828071281069, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=457, endPage=473, ext={EN=ArticleExt(id=1304406865870352441, articleId=1304406865513836599, tenantId=1146029695717560320, journalId=1302319053441957962, language=EN, title=Research on processing technology and quality evaluation system construction of different processed Scutellariae Radix products based on multi index optimization intelligent sensory combination, columnId=null, journalTitle=Chinese Traditional and Herbal Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective To optimize the optimal processing technology of different processed products of Huangqin (Scutellariae Radix, SR) [fried Scutellariae Radix (fSR), Scutellariae Radix charcoal (SRc), wine Scutellariae Radix (wSR)], and explore the correlation between sensory traits such as appearance, color, odor, taste, and the main active ingredients. Method The multi-index response surface methodology (RSM) was used, with baicalin, baicalein, wogonoside, wogonin, and appearance trait scores as evaluation indicators. The analytic hierarchy process and entropy weight method were used to calculate the weight coefficients and comprehensive scores of each indicator. Further utilize central combination design (CCD)-RSM to investigate the effects of temperature and processing time (soaking time and the alcohol ratio) on the processing technology. Using electronic sensory technology (electronic eye, electronic nose, electronic tongue) to analyze the response values of samples with different processing levels, and exploring the correlation between sensory traits (color L*, a*, b* value, odor sensor response value, taste sensor response value) and chemical composition through correlation analysis. Results The optimal process parameters were determined as follows: fSR at 205.4 ℃, 6.5 min, SRc at 227.4 ℃, 16 min, and wSR at 180 ℃, 5 min (moistened for 50 min, with a yellow wine dosage of 18.2%). Correlation analysis shows that different degrees of processing of SR have distinguishable sensor response patterns: odor sensors S7 and S10 and taste sensors P6 and P10—P12 in fSR have a strong positive correlation with baicalin and wogonoside; In SRc and wSR, there is a strong negative correlation between multiple sensors and baicalin, while wogonin shows a strong positive correlation with multiple sensors SRc and a strong negative correlation with fSR. The electronic eye color values (L*, a*, b*) are significantly correlated with the degree of processing (ΔE*ab > 1.5). Conclusion Optimizing the process is stable and feasible. The quality evaluation system based on electronic sensory technology can objectively distinguish the degree of processing, and the correlation between characteristics and components revealed provides theoretical basis and innovative methods for determining the endpoint of processing and quality control., authors=LI Yuting, MA Junnan, BU Zhulin, WU Yuhui, MENG Xianglong, ZHANG Shuosheng, authorsList=LI Yuting, MA Junnan, BU Zhulin, WU Yuhui, MENG Xianglong, ZHANG Shuosheng, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1304406865790660664, articleId=1304406865513836599, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=基于多指标优化-智能感官联用的黄芩不同炮制品的炮制工艺研究及质量评价体系构建, columnId=1304140189132149234, journalTitle=中草药, columnName=药剂与工艺, runingTitle=null, highlight=null, articleAbstract=目的 优化黄芩Astragali Radix不同炮制品(炒黄芩、黄芩炭、酒黄芩)的最佳炮制工艺,探究其外观色泽、气味、滋味等感官性状与主要有效成分之间的相关性。方法 利用热分析技术分析热解温度范围,并结合多指标-响应面法(response surface methodology,RSM),以黄芩苷、黄芩素、汉黄芩苷、汉黄芩素含量及黄芩炮制品外观性状评分为评价指标,利用层次分析法与熵权法计算各指标权重系数及综合评分;进一步利用中心组合设计(central combination design,CCD)设计-RSM考察炮制温度与炮制时间(酒黄芩增加闷润时间、黄酒比例)对炮制工艺的影响;利用电子感官技术(电子眼、电子鼻、电子舌)分析不同炮制程度样品的响应值,并通过相关性分析探究感官性状(色泽L*、a*、b*值、气味传感器响应值、滋味传感器响应值)与化学成分之间的相关性。结果 确定最佳工艺参数:炒黄芩为205.4℃、6.5 min,黄芩炭为227.4℃、16 min,酒黄芩为180℃、5 min(闷润50 min,黄酒用量18.2%)。相关性分析表明,不同炮制程度的黄芩具有可区分的传感器响应模式:炒黄芩中气味传感器S7、S10与滋味传感器P6、P10~P12对黄芩苷与汉黄芩苷呈同步强正相关;黄芩炭和酒黄芩中则普遍转为多传感器与黄芩苷的强负相关,且汉黄芩素在黄芩炭中与多传感器呈强正相关,而在炒黄芩中呈强负相关;电子眼色度值L*、a*、b*与炮制程度显著关联(ΔE*ab>1.5)。结论 优化工艺稳定可行,基于电子感官技术构建的质量评价体系可客观区分炮制程度,揭示的“性状-成分”相关性为炮制终点判定及质量控制提供了理论依据与创新方法。, authors=李宇婷1,2,3,4, 马俊楠5, 卜竹林1,2,3,4, 吴宇慧1,2,3,4, 孟祥龙1,2,3,4, 张朔生1,2,3,4, authorsList=李宇婷, 马俊楠, 卜竹林, 吴宇慧, 孟祥龙, 张朔生, authorCompany=1 山西中医药大学中药与食品工程学院, 山西 晋中 030619;
2 中药炮制技术传承基地(山西), 山西 晋中 030619;
3 中药炮制山西省重点实验室, 山西 晋中 030619;
4 中药材加工炮制传承与创新研究室, 山西 晋中 030619;
5 大连医科大学中西医结合学院 中药方剂教研室, 辽宁 大连 116044, correspAuthors=张朔生, authorNote=李宇婷: 李宇婷(2001—),女,硕士研究生,研究方向为中药炮制学。E-mail: 2497147877@qq.com, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=Y0y+RFV7yjLuYi8N5oZQBQ==, pdfFileSize=3774827, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=山西省中医药科技创新工程项目 (CZ2023041_019); 中药炮制山西省重点实验室开放课题基金资助项目 (2023PZKF002); 太原市揭榜挂帅项目“山西道地中药饮片质量提升关键技术研究及产业化” (2023048); 山西省教育厅2024年度研究生教育创新计划研究生科研创新项目 (2024SJ340); 山西中医药大学科技创新团队项目 (2022TD1014); 山西省科研计划专项中药炮制山西省重点实验室建设 (202404010920012); 中药炮制研究创新团队中药材加工炮制传承与创新重点研究室 (zyyyjs2024020))}, authors=[Author(id=1307443202940756486, tenantId=1146029695717560320, journalId=null, articleId=1304406865513836599, orderNo=null, firstName=null, middleName=null, 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基于多指标优化-智能感官联用的黄芩不同炮制品的炮制工艺研究及质量评价体系构建
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李宇婷, 马俊楠, 卜竹林, 吴宇慧, 孟祥龙, 张朔生
中草药 | 药剂与工艺 2026,57(2): 457-473
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中草药 |药剂与工艺 2026 , 57 (2) : 457 -473
基于多指标优化-智能感官联用的黄芩不同炮制品的炮制工艺研究及质量评价体系构建
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李宇婷, 马俊楠, 卜竹林, 吴宇慧, 孟祥龙, 张朔生
作者信息
通讯作者:
张朔生
作者简介:
李宇婷: 李宇婷(2001—),女,硕士研究生,研究方向为中药炮制学。E-mail: 2497147877@qq.com
Research on processing technology and quality evaluation system construction of different processed Scutellariae Radix products based on multi index optimization intelligent sensory combination
LI Yuting, MA Junnan, BU Zhulin, WU Yuhui, MENG Xianglong, ZHANG Shuosheng
Affiliations
doi: 10.7501/j.issn.0253-2670.2026.02.008
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目的 优化黄芩Astragali Radix不同炮制品(炒黄芩、黄芩炭、酒黄芩)的最佳炮制工艺,探究其外观色泽、气味、滋味等感官性状与主要有效成分之间的相关性。方法 利用热分析技术分析热解温度范围,并结合多指标-响应面法(response surface methodology,RSM),以黄芩苷、黄芩素、汉黄芩苷、汉黄芩素含量及黄芩炮制品外观性状评分为评价指标,利用层次分析法与熵权法计算各指标权重系数及综合评分;进一步利用中心组合设计(central combination design,CCD)设计-RSM考察炮制温度与炮制时间(酒黄芩增加闷润时间、黄酒比例)对炮制工艺的影响;利用电子感官技术(电子眼、电子鼻、电子舌)分析不同炮制程度样品的响应值,并通过相关性分析探究感官性状(色泽L*、a*、b*值、气味传感器响应值、滋味传感器响应值)与化学成分之间的相关性。结果 确定最佳工艺参数:炒黄芩为205.4℃、6.5 min,黄芩炭为227.4℃、16 min,酒黄芩为180℃、5 min(闷润50 min,黄酒用量18.2%)。相关性分析表明,不同炮制程度的黄芩具有可区分的传感器响应模式:炒黄芩中气味传感器S7、S10与滋味传感器P6、P10~P12对黄芩苷与汉黄芩苷呈同步强正相关;黄芩炭和酒黄芩中则普遍转为多传感器与黄芩苷的强负相关,且汉黄芩素在黄芩炭中与多传感器呈强正相关,而在炒黄芩中呈强负相关;电子眼色度值L*、a*、b*与炮制程度显著关联(ΔE*ab>1.5)。结论 优化工艺稳定可行,基于电子感官技术构建的质量评价体系可客观区分炮制程度,揭示的“性状-成分”相关性为炮制终点判定及质量控制提供了理论依据与创新方法。
黄芩  /  工艺优化  /  中心组合设计-响应面法  /  层次分析法  /  熵权法  /  智能感官  /  质量评价  /  色泽  /  气味  /  滋味  /  热分析技术  /  黄芩苷  /  黄芩素  /  汉黄芩苷  /  汉黄芩素  /  电子眼  /  电子鼻  /  电子舌
Objective To optimize the optimal processing technology of different processed products of Huangqin (Scutellariae Radix, SR) [fried Scutellariae Radix (fSR), Scutellariae Radix charcoal (SRc), wine Scutellariae Radix (wSR)], and explore the correlation between sensory traits such as appearance, color, odor, taste, and the main active ingredients. Method The multi-index response surface methodology (RSM) was used, with baicalin, baicalein, wogonoside, wogonin, and appearance trait scores as evaluation indicators. The analytic hierarchy process and entropy weight method were used to calculate the weight coefficients and comprehensive scores of each indicator. Further utilize central combination design (CCD)-RSM to investigate the effects of temperature and processing time (soaking time and the alcohol ratio) on the processing technology. Using electronic sensory technology (electronic eye, electronic nose, electronic tongue) to analyze the response values of samples with different processing levels, and exploring the correlation between sensory traits (color L*, a*, b* value, odor sensor response value, taste sensor response value) and chemical composition through correlation analysis. Results The optimal process parameters were determined as follows: fSR at 205.4 ℃, 6.5 min, SRc at 227.4 ℃, 16 min, and wSR at 180 ℃, 5 min (moistened for 50 min, with a yellow wine dosage of 18.2%). Correlation analysis shows that different degrees of processing of SR have distinguishable sensor response patterns: odor sensors S7 and S10 and taste sensors P6 and P10—P12 in fSR have a strong positive correlation with baicalin and wogonoside; In SRc and wSR, there is a strong negative correlation between multiple sensors and baicalin, while wogonin shows a strong positive correlation with multiple sensors SRc and a strong negative correlation with fSR. The electronic eye color values (L*, a*, b*) are significantly correlated with the degree of processing (ΔE*ab > 1.5). Conclusion Optimizing the process is stable and feasible. The quality evaluation system based on electronic sensory technology can objectively distinguish the degree of processing, and the correlation between characteristics and components revealed provides theoretical basis and innovative methods for determining the endpoint of processing and quality control.
Scutellariae Radix  /  process optimization  /  central combination design-response surface method  /  analytic hierarchy process  /  entropy weight method  /  intelligent sensory  /  quality evaluation  /  color  /  smell  /  taste  /  thermal analysis technology  /  baicalin  /  scutellarin  /  wogonoside  /  wogonin  /  electronic eye  /  electronic nose  /  electronic tongue
李宇婷, 马俊楠, 卜竹林, 吴宇慧, 孟祥龙, 张朔生. 基于多指标优化-智能感官联用的黄芩不同炮制品的炮制工艺研究及质量评价体系构建. 中草药, 2026 , 57 (2) : 457 -473 . DOI: 10.7501/j.issn.0253-2670.2026.02.008
LI Yuting, MA Junnan, BU Zhulin, WU Yuhui, MENG Xianglong, ZHANG Shuosheng. Research on processing technology and quality evaluation system construction of different processed Scutellariae Radix products based on multi index optimization intelligent sensory combination[J]. Chinese Traditional and Herbal Drugs, 2026 , 57 (2) : 457 -473 . DOI: 10.7501/j.issn.0253-2670.2026.02.008

    山西省中医药科技创新工程项目 (CZ2023041_019); 中药炮制山西省重点实验室开放课题基金资助项目 (2023PZKF002); 太原市揭榜挂帅项目“山西道地中药饮片质量提升关键技术研究及产业化” (2023048); 山西省教育厅2024年度研究生教育创新计划研究生科研创新项目 (2024SJ340); 山西中医药大学科技创新团队项目 (2022TD1014); 山西省科研计划专项中药炮制山西省重点实验室建设 (202404010920012); 中药炮制研究创新团队中药材加工炮制传承与创新重点研究室 (zyyyjs2024020)

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2026年第57卷第2期
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doi: 10.7501/j.issn.0253-2670.2026.02.008
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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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