Article(id=1304406864318452479, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304406828071281069, articleNumber=null, orderNo=null, doi=10.7501/j.issn.0253-2670.2026.02.010, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1757260800000, receivedDateStr=2025-09-08, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788924431161, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788924431161, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788924431161, creator=13701087609, updateTime=1788924431161, updator=13701087609, issue=Issue{id=1304406828071281069, tenantId=1146029695717560320, journalId=1302319053441957962, year='2026', volume='57', issue='2', pageStart='393', pageEnd='788', issueExtLink='null', onlineDate='null', pubDate='1769529600000', pubDateStr='2026-01-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788924422518, creator='13701087609', updateTime=1788924652596, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304407793138688830, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304406828071281069, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304407793138688831, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304406828071281069, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=485, endPage=499, ext={EN=ArticleExt(id=1304406864633025281, articleId=1304406864318452479, tenantId=1146029695717560320, journalId=1302319053441957962, language=EN, title=Optimization of calcination processing technology based on AHP-CRITIC mixed entropy method and health risk assessment of heavy metals elements in Haliotidis Concha, columnId=null, journalTitle=Chinese Traditional and Herbal Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective To investigate the effects of calcination temperature on the phase composition and chemical constituents of Shijueming (Haliotidis Concha, HC), optimize its processing methodology, and conduct comparative analysis and health risk assessment of heavy metal content in HC and calcined HC. Methods Thermal effects during processing at different calcination temperatures were examined via thermogravimetric-differential thermal analysis (TG-DTA). Primary phase transformations were analyzed using X-ray diffraction (XRD), while compositional changes were assessed by Fourier transform infrared spectroscopy (FTIR) to preliminarily screen the key factor “calcination temperature” affecting HC processing. Simultaneously, the optimal processing parameters for HC were determined using the AHP-CRITIC mixed entropy method combined with orthogonal experiments, with CaCO₃ content, crispness, and color as evaluation criteria. Calcined HC were processed according to the optimized method. Inductively coupled plasma mass spectrometry (ICP-MS) was employed to analyze 20 batches of HC and calcined HC for Pb, Cd, As, Hg, and Cu in 20 batches of HC and calcined calcined HC. Using HC powder as a reference, theoretical maximum limits for these five heavy metals and toxic elements were calculated. Daily exposure and target hazard quotient (THQ) were further assessed to evaluate health risks, providing a reference for quality and safety evaluation of HC. Results Preliminary screening of calcination temperatures indicated an optimal range of 400—600 ℃. Using the AHP-CRITIC mixed entropy method, the optimized calcination process for HC was determined as follows: Crush HC to a particle size < 1 cm, place in a muffle furnace, set the temperature to 600 ℃, and calcine for 90 min. After calcination, the organic matter content of HC decreased while calcium carbonate content increased. The calcined HC showed reduced levels of As and Hg, with minimal changes in Cu, Cd and Pb. Health risk assessment indicated that all 20 batches of HC and calcined HC posed no significant health hazards to humans. Notably, the As and Hg levels in the slices were significantly lower than those in the raw material (P < 0.05). Conclusion By integrating phase and compositional changes before and after processing, this study employed the AHP-CRITIC mixed entropy method to scientifically and comprehensively optimize the calcination process for HC. The screening results are scientifically reliable, providing new scientific evidence for quality management and clinical application of HC and calcined HC. Conducting health risk assessments of heavy metals and harmful elements in HC before and after processing provides reference for the safe clinical use of HC and other shell-derived Chinese medicinal materials., authors=WANG Weichao, YANG Zhihan, ZHOU Jingwei, LUO Chuang, YANG Xiaoyan, FEI Wenbo, AI Guangli, YANG Lian, WANG Fu, HU Yuan, LIU Youping, CHEN Hongping, CHEN Lin, LUO Xiao, authorsList=WANG Weichao, YANG Zhihan, ZHOU Jingwei, LUO Chuang, YANG Xiaoyan, FEI Wenbo, AI Guangli, YANG Lian, WANG Fu, HU Yuan, LIU Youping, CHEN Hongping, CHEN Lin, LUO Xiao, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1304406864549139200, articleId=1304406864318452479, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=基于AHP-CRITIC混合加权法优选石决明煅制工艺及其重金属及有害元素健康风险评估, columnId=1304140189132149234, journalTitle=中草药, columnName=药剂与工艺, runingTitle=null, highlight=null, articleAbstract=目的 明确煅制温度对石决明Haliotidis Concha物相及成分组成的影响，优选石决明的炮制工艺，并对石决明药材及其饮片所含重金属元素含量进行对比及健康风险评估。方法 通过热重-差热分析（thermogravimetric-differential thermal analysis，TG-DTA）考察不同煅制温度下饮片的热效应发生过程，X射线衍射法（X-ray diffraction，XRD）考察主要物相转变，傅里叶变换红外光谱法（Fourier transform infrared spectroscopy，FTIR）考察成分组成变化，对影响石决明煅制工艺的关键因素“煅制温度”进行初筛。同时基于AHP-CRITIC混合加权法，结合正交试验，以CaCO₃含量、酥脆程度、色泽为评价指标，优选石决明的最佳炮制工艺参数；按最佳炮制工艺炮制饮片，采用电感耦合等离子体质谱法（inductively coupled plasma mass spectrometry，ICP-MS）对20批石决明药材及煅石决明饮片中Pb、Cd、As、Hg、Cu 5种重金属及有害元素进行测定分析；参考“中药中外源性有害残留物安全风险评估技术指导原则”与“中药有害残留物限量制定指导原则（通则9302），推算石决明中5种重金属及有害元素的最大限量理论值，同时计算其日暴露量和靶标危害系数（target hazard quotients，THQ）进行健康风险评估，为石决明的质量安全评价提供参考依据。结果 煅制温度初筛结果显示，煅制温度在400～600℃为宜，结合AHP-CRITIC混合加权法优选出石决明煅制工艺为取石决明药材，打碎至药材粒径＜1 cm，置马弗炉中，设置煅烧温度600℃，煅制90 min，即得。石决明煅制后有机质成分损失，CaCO₃含量相对增加，煅石决明饮片中As、Hg元素含量降低，Cu、Cd、Pb元素含量变化不大。健康风险评估结果显示，20批石决明药材及煅石决明饮片不会对人体健康产生明显的危害，且饮片中As、Hg元素含量显著低于药材（P＜0.05）。结论 结合药材炮制前后物相及成分变化，采用AHP-CRITIC混合加权法更加科学、全面地优选石决明煅制工艺，筛选结果科学可靠，为石决明药材及煅石决明饮片的质量管理和临床应用提供了新的科学依据。对石决明药材炮制前后重金属及有害元素进行健康风险评估，为石决明及其他贝壳类中药的临床安全用药提供参考。, authors=王伟超¹, 杨智涵¹, 周靖惟², 罗创¹, 杨小艳³, 费文波², 艾光丽³, 仰莲², 王福¹, 胡媛¹, 刘友平¹, 陈鸿平¹, 陈林¹, 罗霄³, authorsList=王伟超, 杨智涵, 周靖惟, 罗创, 杨小艳, 费文波, 艾光丽, 仰莲, 王福, 胡媛, 刘友平, 陈鸿平, 陈林, 罗霄, authorCompany=1 成都中医药大学药学院, 中药种质资源创新与高效利用四川省重点实验室, 四川 成都 611137;
2 四川新绿色药业科技发展有限公司, 四川 彭州 611930;
3 成都市药品检验研究院 国家药品监督管理局中药材质量监测评价重点实验室, 四川 成都 610045, correspAuthors=陈林, authorNote=王伟超: 王伟超，硕士研究生，从事临床中药学研究。E-mail: 1763233979@qq.com, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=+YiT03xo6Fb7eYUPbrSaXg==, pdfFileSize=2684751, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=国家中医药管理局应用基础研究课题 (gzyjc20210901))}, authors=[Author(id=1307432707445776666, tenantId=1146029695717560320, journalId=null, articleId=1304406864318452479, orderNo=null, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=null, authorType=null, ext={EN=AuthorExt(id=null, tenantId=null, 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Li M Y, Wu Y C, Huang L, et al. Composition, structure and comprehensive utilization of abalone shell:A review[J]. Sustain Chem Pharm, 2025, 43:101892.
姜威, 李晶峰, 高久堂, 等. 石决明的化学成分及药理作用[J]. 吉林中医药, 2015, 35(3):272-274.
林小明. 石决明炮制最佳工艺条件的选择[J]. 中国中药杂志, 1994, 19(10):603.
李超英, 高雅言, 杨辛欣, 等. 石决明炮制工艺研究[J]. 中国药房, 2008, 19(33):2621-2623.
孙承三, 丘花花, 李莹莹, 等. 石决明煅制温度初步研究[J]. 中成药, 2011, 33(1):92-95.
王文凯, 彭小平. 石决明炮制研究[J]. 中成药, 2004, 26(5):35-37.
陈为宏. 石决明加工炮制工艺[J]. 中成药研究, 1983, 5(8):42.
左甜甜, 王莹, 张磊, 等. 中药中外源性有害残留物安全风险评估技术指导原则[J]. 药物分析杂志, 2019, 39(10):1902-1907.
谢佳玲, 彭颖洁, 李春梅, 等. 海产品重金属污染现状及检测技术研究进展[J]. 现代农业科技, 2024(21):137-141.
郭愿生, 左甜甜, 陈安珍, 等. 海洋中药中重金属及有害元素质量控制进展及未来发展方向[J]. 中国新药杂志, 2024, 33(9):877-884.
黄勇, 杨晓彬, 林颖, 等. 两种基原蛤壳有效成分与重金属元素及有害元素比较[J]. 亚太传统医药, 2023, 19(11):56-60.
李超男, 曹振. 石墨炉原子吸收光谱法检测牡蛎中镉元素含量[J]. 现代食品, 2024, 30(17):203-206.
郑晓霞, 陈晓璐, 黄美仙, 等. ICP-MS法结合化学计量学分析不同产地牡蛎无机元素分布及风险评估[J]. 中南药学, 2024, 22(10):2729-2736.
杨丽, 李雪莲, 赵梓辰, 等. 差热分析法鉴别碳酸钙类矿物药的研究[J]. 时珍国医国药, 2014, 25(10):2412-2414.
韩世虎, 赵宇飞. 有机蒙脱土的制备与表征[J]. 成都大学学报:自然科学版, 2017, 36(4):414-416.
林郁郁. CaO伴随生物质热裂解制油在线脱氧的实验研究[D]. 上海:上海交通大学, 2011.
毛银雪. 不同产地与基源石决明质量评价与煅制过程变化研究[D]. 连云港:江苏海洋大学, 2022.
林郁郁, 张楚, 张健, 等. CaO伴随生物质热裂解固体产物分析[J]. 工程热物理学报, 2011, 32(12):2133-2136.
毛银雪, 牛淑睿, 杨鑫, 等. 不同产地与基源石决明的碳酸钙含量及红外光谱比较研究[J]. 广东化工, 2021, 48(21):32-36.
曾晓涛, 陈艳琰, 乐世俊, 等. 基于AHP-CRITIC综合赋权法的地锦草质量标志物量化辨识[J]. 中国中药杂志, 2022, 47(19):5193-5202.
陶明宝, 鄢玉芬, 陈林, 等. 瓦楞子的炮制工艺优选[J]. 中国实验方剂学杂志, 2017, 23(21):24-29.
丁涵, 徐忠坤, 王振中, 等. 基于AHP-CRITIC混合加权法和Box-Behnken设计-响应面法优化羌芩颗粒成型工艺及其物理指纹图谱研究[J]. 中草药, 2024, 55(3):787-797.
梁佳, 王章伟, 邓双炳, 等. ICP-MS法测定喜炎平注射液中重金属及有害元素[J]. 中草药, 2019, 50(24):6002-6008.
傅必如, 卓韦杰, 黄炫秀, 等. 基于4种生物碱类成分含量测定结合化学计量学评价不同产地鸭跖草药材质量研究[J]. 中国中药杂志, 2025, 50(9):2422-2431.
卿颖. 上海市老年人群重金属铅、镉、汞外暴露及健康风险评估[A]//中国营养学会第十五届全国营养科学大会论文汇编[C]. 北京:中国营养学会第十五届全国营养科学大会, 2022:381.
黎晓欣, 路浚齐, 李琼霞. 中药重金属及有害元素健康风险评估的研究进展[J]. 中国中药杂志, 2024, 49(17):4630-4636.
毕梦娇. 铅污染物影响体内硒稳态诱发机体损失机理的研究[D]. 济南:山东大学, 2019.
丁鸿, 杨杏芬. 环境镉危害早期健康效应风险评估的研究进展[J]. 国外医学:卫生学分册, 2007(5):279-282.
刘佳琳. 中国居民膳食镉和无机砷暴露所致癌症疾病负担研究[D]. 武汉:华中科技大学, 2023.
李志强, 韩俊艳, 郭宇俊, 等. 汞毒性研究进展[J]. 畜牧与饲料科学, 2018, 39(12):64-68.
于燕, 李惠玲. 铜代谢及其相关疾病研究进展[J]. 环境与健康杂志, 2018, 35(3):272-276.
李君翔, 倪琳, 王亚飞, 等. 基于多种算法建立牡蛎及石决明的拉曼光谱鉴别模型[J]. 中国现代应用药学, 2023, 40(4):477-482.
宋金斌. 《元亨疗马集》中药物炮制的整理[J]. 中兽医医药杂志, 1986, 5(1):29-31.
张洪怡, 周靖惟, 刘佳雯, 等. 基于AHP-CRITIC复合加权法优选牡蛎的炮制工艺及其重金属元素健康风险评估[J]. 中草药, 2025, 56(5):1549-1563.)