Article(id=1304406860656829041, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304406818550206926, articleNumber=null, orderNo=null, doi=10.7501/j.issn.0253-2670.2026.01.022, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1758038400000, receivedDateStr=2025-09-17, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788924430287, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788924430287, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788924430287, creator=13701087609, updateTime=1788924430287, updator=13701087609, issue=Issue{id=1304406818550206926, tenantId=1146029695717560320, journalId=1302319053441957962, year='2026', volume='57', issue='1', pageStart='1', pageEnd='389', issueExtLink='null', onlineDate='null', pubDate='1768147200000', pubDateStr='2026-01-12', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788924420249, creator='13701087609', updateTime=1788924674802, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304407886289986387, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304406818550206926, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304407886289986388, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304406818550206926, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=236, endPage=255, ext={EN=ArticleExt(id=1304406861009150579, articleId=1304406860656829041, tenantId=1146029695717560320, journalId=1302319053441957962, language=EN, title=Bibliometrics and global patent analysis of Uncariae Ramulus Cum Uncis research: Dynamics, focus and prospects, columnId=null, journalTitle=Chinese Traditional and Herbal Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective To comprehensively analyze the research trends and focuses of Gouteng (Uncariae Ramulus Cum Uncis) from bibliometric and global patent perspectives, providing forward-looking references for its future clinical application and in-depth research. Methods Literature was retrieved from four databases: China National Knowledge Infrastructure (CNKI), Wanfang, VIP, and Web of Science (WOS) with Uncariae Ramulus Cum Uncis as the keyword. Retrieved publications were imported into NoteExpress for deduplication and screening. Software including Excel, Origin, CiteSpace, and VOSviewer were used to visually analyze the current research status and development trends of Uncariae Ramulus Cum Uncis in domestic and international publications, covering publication trends, national distribution, publication institutions, journal of publication, authors, and keywords. The Incopat patent database was searched to analyze global patent applications related to Uncariae Ramulus Cum Uncis, including trends in patent applications, geographical distribution, applicants, and technology fields. Results A total of 1 713 Chinese publications and 594 English publications met the inclusion criteria. China was the primary contributor to publications, with international attention increasing gradually in recent years. Core research teams have emerged in this field, but collaboration among institutions requires strengthening. In recent years, there has been an overlap in the research hotspots of Chinese and English literature in the field of Uncariae Ramulus Cum Uncis, both focusing on the pharmacological components and action mechanisms of Uncariae Ramulus Cum Uncis. Chinese studies specifically emphasize Tianma Gouteng Decoction and its use in hypertension treatment, identifying bioactive compounds and elucidating regulatory mechanisms. English publications focus on phytochemistry, anti-inflammation, antioxidation, and the potential efficacy in neurological diseases. Based on a search of the Incopat patent database, 8 048 patents were initially screened. After merging patent families, 6 251 patents were retained, among which 5 461 were domestic patents, accounting for 87.36% and occupying a dominant position. Conclusion Research in the field of Uncariae Ramulus Cum Uncis shows a trend of continuous expansion and deepening. Overall, it is shifting from traditional Chinese medicine practice to a development path featuring multi-disciplinary collaborative innovation and in-depth analysis of molecular-level mechanisms. Although China dominates international patent applications related to Uncariae Ramulus Cum Uncis, there are key drawbacks: A large number of patents have expired, the degree of transformation and implementation is limited, and market expansion is weak., authors=CUI Qiuyue, LIU Jia, ZHANG Yufeng, XIA Qingqing, ZHAO Ruining, WANG Jin, HUA Haibing, authorsList=CUI Qiuyue, LIU Jia, ZHANG Yufeng, XIA Qingqing, ZHAO Ruining, WANG Jin, HUA Haibing, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1304406860912681586, articleId=1304406860656829041, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=钩藤研究的文献计量学与全球专利分析：动态、焦点与前瞻, columnId=1304140194819629763, journalTitle=中草药, columnName=数据挖掘与循证医学, runingTitle=null, highlight=null, articleAbstract=目的 从文献计量学和全球专利的角度对钩藤的研究动态与焦点进行全面分析，为未来钩藤的临床应用和深入研究提供前瞻参考。方法 以钩藤为关键词检索中国知网（CNKI）、万方（Wanfang）、维普（VIP）、Web of Science（WOS）4个数据库，将文献导入NoteExpress文献管理软件中进行查重和筛选。利用Excel、Origin、CiteSpace、VOSviewer等软件，从发文趋势与国家分布、发文机构、发文期刊、发文作者、关键词等维度对国内外的钩藤研究现状与发展趋势进行可视化分析。通过Incopat专利数据库从专利申请趋势、全球地域分布、专利申请人及专利技术领域等方面检索并分析钩藤相关全球专利申请情况。结果 共检索到符合标准的中文文献1 713篇，英文文献594篇。发文国家以中国为主，国际上对钩藤的关注度也显著提升。钩藤领域的核心团队已初步形成，但机构间合作有待加强。近年来钩藤领域中英文文献研究热点存在交叉现象，均聚焦于钩藤的药理活性成分、作用机制，中文文献聚焦天麻钩藤饮及钩藤用于高血压的治疗及调控机制与活性成分；英文文献侧重于植物化学、抗炎抗氧化作用及神经疾病的潜在疗效。基于Incopat专利数据库检索经初步筛选得到8 048件专利，实施同族合并操作后，保留专利6 251项，其中国内专利数量为5 461，占比87.36%，占据主导地位。结论 钩藤领域研究呈现出不断拓展与深化的态势，整体上正从传统中医药实践转向多学科协同创新与分子水平机制深入解析的发展路径。中国虽然在钩藤专利的国际申请中占据主导地位，却存在关键弊端：专利失效规模较大、转化实施程度有限且市场拓展乏力。, authors=崔秋月¹, 柳佳², 张宇锋², 夏清青², 赵瑞凝³, 王进^1,4, 花海兵², authorsList=崔秋月, 柳佳, 张宇锋, 夏清青, 赵瑞凝, 王进, 花海兵, authorCompany=1 南京中医药大学中医药文献研究院, 江苏 南京 210023;
2 南京中医药大学江阴附属医院, 江苏 无锡 214400;
3 南京中医药大学第一临床医学院, 江苏 南京 210023;
4 江苏省中医流派研究院, 江苏 南京 210023, correspAuthors=王进, authorNote=崔秋月: 崔秋月,硕士研究生,研究方向为中医药文献与文献计量研究。E-mail:orchidyue25@126.com, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=dk3PeL80TpjmOwWkk6r0jA==, pdfFileSize=2390383, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=江苏省中医疫病研究中心开放课题 (JSYB2024KF28); 江苏省中医流派研究院开放课题 (JSZYLP2024040,JSZYLP2024042); 无锡市卫生健康委科技计划项目 (M202329,T202549,M202552); 无锡市中医药科技发展专项重点项目 (ZYZD202404); 无锡市名中医工作室 (锡中医[2023]2号〈11〉))}, authors=null, keywords=[Keyword(id=1304406861160145524, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304406860656829041, language=CN, orderNo=1, keyword=钩藤), Keyword(id=1304406861235642997, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304406860656829041, language=CN, orderNo=2, keyword=文献计量学), Keyword(id=1304406861302751862, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304406860656829041, language=CN, orderNo=3, keyword=可视化分析), Keyword(id=1304406861374055031, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304406860656829041, language=CN, orderNo=4, keyword=专利分析), Keyword(id=1304406861445358200, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304406860656829041, language=CN, orderNo=5, keyword=CiteSpace), Keyword(id=1304406861520855673, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304406860656829041, language=CN, orderNo=6, keyword=VOSviewer), Keyword(id=1304406861642490490, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304406860656829041, language=EN, orderNo=1, keyword=Uncariae Ramulus Cum Uncis), Keyword(id=1304406861713793659, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304406860656829041, language=EN, orderNo=2, keyword=bibliometrics), Keyword(id=1304406861768319612, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304406860656829041, language=EN, orderNo=3, keyword=visual analysis), Keyword(id=1304406861839622781, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304406860656829041, language=EN, orderNo=4, keyword=patent analysis), Keyword(id=1304406861931897470, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304406860656829041, language=EN, orderNo=5, keyword=CiteSpace), Keyword(id=1304406862003200639, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304406860656829041, language=EN, orderNo=6, keyword=VOSviewer)], refs=null, funds=null, companyList=null, figs=null, attaches=null, journal=Journal(id=1302309778002903112, delFlag=0, nameCn=中草药, nameEn=Chinese Traditional and Herbal Drugs, nameHistory1=null, nameHistory2=null, issn=0253-2670, eissn=null, cn=12-1108/R, coden=null, periodic=3, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=cGpSKCP11AF8PAOcTXYWfg==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Traditional and Herbal Drugs, journalRemark=null, publicationField=null, createdTime=1788424446827, updatedTime=1788949289390, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=cGpSKCP11AF8PAOcTXYWfg==, picEn=Xw//kxUC3ON4eHxev0QLhQ==, jcr=null, cjcr=null, exts=[JournalExt(id=1304511127375863983, language=CN, name=中草药, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949289411, updatedTime=1788949289411, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://www.tiprpress.com/zcy/author/login, submissionEditorUrl=https://www.tiprpress.com/zcy/editor/login, submissionReviewUrl=https://www.tiprpress.com/zcy/reviewer/login, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1304511127442972848, language=EN, name=Chinese Traditional and Herbal Drugs, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949289427, updatedTime=1788949289427, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://www.tiprpress.com/zcy/author/login, submissionEditorUrl=https://www.tiprpress.com/zcy/editor/login, submissionReviewUrl=https://www.tiprpress.com/zcy/reviewer/login, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1302319053441957962, websiteList=[Website(id=1302319176408912052, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1302319053441957962, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zcy/CN, language=CN, createTime=1788426687576, createBy=18614031015, updateTime=1788427346252, updateBy=18614031015, name=中草药-中文, tplId=1146099689490845704, title=中草药, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1302322043651904087, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=articleTextType, value=kx, createTime=1788427371180, updateTime=1788427371180, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043593183828, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=banner, value=null, createTime=1788427371166, updateTime=1788427371166, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043672875610, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=grayFlag, value=0, createTime=1788427371185, updateTime=1788427371185, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043584795219, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=logo, value=https://castjournals.cast.org.cn/joweb/zcy/CN/file/pic?fileId=uiD1gpiRqR++OLOz4iKzDg==, createTime=1788427371164, updateTime=1788427371164, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043689652828, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=minRunFlag, value=0, createTime=1788427371189, updateTime=1788427371189, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043643515478, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zcy/CN/file/pic, createTime=1788427371178, updateTime=1788427371178, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043681264219, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=silenceFlag, value=0, createTime=1788427371187, updateTime=1788427371187, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043601572437, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1788427371168, updateTime=1788427371168, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043660292696, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=themeColor, value=null, createTime=1788427371182, updateTime=1788427371182, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043668681305, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=themeStyle, value=null, createTime=1788427371184, updateTime=1788427371184, creator=18614031015, updator=18614031015)]), Website(id=1302319176715096246, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1302319053441957962, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zcy/EN, language=EN, createTime=1788426687649, createBy=18614031015, updateTime=1788427341161, updateBy=18614031015, name=中草药-英文, tplId=1146101810881728533, title=Chinese Traditional and Herbal Drugs, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1302322015206134340, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=articleTextType, value=kx, createTime=1788427364398, updateTime=1788427364398, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015185162817, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=banner, value=null, createTime=1788427364393, updateTime=1788427364393, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015227105863, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=grayFlag, value=0, createTime=1788427364403, updateTime=1788427364403, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015176774208, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=logo, value=https://castjournals.cast.org.cn/joweb/zcy/EN/file/pic?fileId=uiD1gpiRqR++OLOz4iKzDg==, createTime=1788427364391, updateTime=1788427364391, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015239688777, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=minRunFlag, value=0, createTime=1788427364406, updateTime=1788427364406, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015201940035, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zcy/EN/file/pic, createTime=1788427364397, updateTime=1788427364397, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015235494472, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=silenceFlag, value=0, createTime=1788427364405, updateTime=1788427364405, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015193551426, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1788427364395, updateTime=1788427364395, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015214522949, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=themeColor, value=null, createTime=1788427364400, updateTime=1788427364400, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015218717254, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=themeStyle, value=null, createTime=1788427364401, updateTime=1788427364401, creator=18614031015, updator=18614031015)])], journalTitle=中草药, weixinUrl=null, journalUrl=https://www.tiprpress.com/zcy, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Traditional and Herbal Drugs, journalPhotoCn=cGpSKCP11AF8PAOcTXYWfg==, journalPhotoEn=Xw//kxUC3ON4eHxev0QLhQ==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zcy/CN/10.7501/j.issn.0253-2670.2026.01.022, detailUrlEn=https://castjournals.cast.org.cn/joweb/zcy/EN/10.7501/j.issn.0253-2670.2026.01.022, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zcy/CN/PDF/10.7501/j.issn.0253-2670.2026.01.022, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zcy/EN/PDF/10.7501/j.issn.0253-2670.2026.01.022, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1788924430287, fullTextJson=null, articleText=null, reference=崔晓燕,郑晓明,郭树垚,等.基于网络药理学、分子对接与实验验证探究钩藤治疗热性惊厥的作用机制[J]. 中草药, 2024, 55(15):5154-5165.
梁·陶弘景编.尚志钧,尚元胜辑校.本草经集注:辑校本[M]. 北京:人民卫生出版社, 1994:383.
苏敬.新修本草[M]. 合肥:安徽科学技术出版社,2005:352.
明·李时珍.本草纲目(第一册)[M]. 校点本.北京:人民卫生出版社, 1977:1319.
梁·陶弘景集.尚志钧辑校.名医别录[M]. 北京:人民卫生出版社, 1986:267.
唐·甄权撰.尚志钧撰,尚志钧辑释.药性论:辑释本[M]. 合肥:安徽科学技术出版社, 2006:47.
清·凌奂.本草害利[M]. 北京:中医古籍出版社,1982:37-38.
王悦宸,侯亚威,王振国.基于文献计量学的丹参研究现状与热点分析[J]. 中草药, 2025, 56(4):1318-1337.
Lppm Universitas Andalas.丝绸地区甘比尔叶提取物抑制动物饲料中原生动物和甲烷气体的剂量:印度尼西亚, IDS00202414269[P]. 2024-12-31.
Lppm Universitas Andalas. Trichilia trijuga种子提取物和甘比尔(Uncaria gambir)加工废物的混合物对Crocidolomia binotalis Zeller幼虫死亡率和发育的影响(鳞翅目:PYRALIDAE):印度尼西亚, IDS00202311170A[P]. 2024-10-22.
Lppm Universitas Andalas.添加GAMBIR组成变异在改善聚维尼醇, MXENE纳米颗粒生物复合材料电性能中的方法:印度尼西亚, IDS00202208911A[P]. 2022-10-03.
四川金堂海纳生物医药技术研究所.一种治疗头痛的新型中药组合物及制备方法:中国,CN201711037656.0[P]. 2018-03-23.
四川金堂海纳生物医药技术研究所.一种治疗眩晕的新型中药组合物及其制备方法:中国,CN201610844876.3[P]. 2016-11-30.
四川金堂海纳生物医药技术研究所.一种可有效治疗耳鸣的汤剂药物及制备方法:中国,CN201711035385.5[P]. 2018-03-06.
四川金堂海纳生物医药技术研究所.一种治疗风湿痹痛的汤剂药物及其制备方法:中国,CN201710918499.8[P]. 2017-12-26.
广州王老吉药业股份有限公司.一种用于功能性消化不良的药物组合物及其制备方法和应用:中国,CN202411789394.3[P]. 2025-04-01.
广州王老吉药业股份有限公司.一种治疗胃肠疾病中药泡腾片及其制备方法:CN200610011183.2[P]. 2012-09-12.
石洁.天麻钩藤饮的临床应用进展[J]. 世界中医药,2008, 3(1):61-63.
张胜.羚角钩藤汤中桑叶、菊花配伍意义探析[J]. 吉林中医药, 2005, 25(10):52-53.
于泽,冼绍祥,赵立诚.天麻钩藤饮临床应用研究进展[J]. 新中医, 2003, 35(4):70-72.
张彦彦,李晶洁,龙芸鸾,等.天麻钩藤饮防治神经系统疾病的研究进展[J]. 中成药, 2022, 44(9):2901-2905.
郇家铭,滑振,陈昊昱,等.钩藤玄参方治疗高血压病的疗效评价:基于真实世界数据的回顾性队列研究[J]. 世界科学技术-中医药现代化, 2025, 27(3):832-841.
田昕彤,周巍,杨继,等.钩藤及其配伍制剂治疗高血压的研究进展[J]. 中草药, 2023, 54(13):4395-4403.
阿如娜,高铸烨,杜天依,等.基于CiteSpace可视化分析天麻钩藤饮的研究现状与发展趋势[J]. 中西医结合心脑血管病杂志, 2024, 22(15):2713-2719.
龙红萍,易健,蔺晓源,等.基于UPLC-ESI-Q-TOFMS/MS技术的复方钩藤降压片化学成分分析[J]. 中药新药与临床药理, 2023, 34(3):396-403.
张雯昕,张春霞,韩凌飞,等.钩藤网络药理学多靶点效应价值研究进展[J]. 中国药科大学学报, 2025,56(3):376-381.
胡梦妮,张小蕾,荣臻,等.基于PI3K/AKT信号通路探究天麻钩藤饮对MPTP诱导帕金森病小鼠的作用机制[J]. 中国老年学杂志, 2025, 45(2):345-351.
程申,郎旭东,方芳,等.天麻钩藤饮对抽动障碍模型大鼠行为改善及神经保护作用[J]. 中国现代应用药学, 2023, 40(11):1475-1480.
陈宏,冯大庆,张明浩,等.天麻钩藤饮对癫痫小鼠海马区miRNA-9表达的影响及对神经损伤的保护机制[J]. 中华中医药杂志, 2024, 39(3):1499-1503.
Wu X F, Jiang X X. Systematic review and meta analysis of randomized controlled trials on Tianmagouteng Decoction in treatment of primary hypertension with liver Yang hyperactivity syndrome[J]. J Tradit Chin Med, 2013,33(1):15-18.
姚佳梅,钟博宇,时拥月,等.天麻钩藤饮对自发性高血压大鼠血管衰老中N6-甲基腺苷甲基化的影响[J]. 中华中医药杂志, 2025, 40(3):1098-1105.
时拥月,符雁榕,秦钦,等.天麻钩藤饮对AngII诱导血管平滑肌细胞氧化应激中PINK1/Parkin通路的影响[J]. 中国中药杂志, 2024, 49(14):3894-3900.
胡世云,冼绍祥,赵立诚,等.天麻钩藤饮对肾血管性高血压大鼠醛固酮和血管紧张素II的影响[J]. 安徽中医学院学报, 2009, 28(1):41-43.
于潇,祝琳琳,刘婕,等.钩藤中单萜吲哚类生物碱成分及其药理活性的研究进展[J]. 中草药, 2021, 52(19):6052-6065.
汪江涛,丁伯平,柏松,等.钩藤碱对肾性高血压大鼠心肌中叶素及其受体表达的影响[J]. 中成药, 2013,35(6):1129-1133.
张应联,吴亚吉,李燕芳.钩藤碱对葡萄糖-6-磷酸酶缺乏的肝细胞脂质代谢的研究[J]. 中国临床药理学杂志, 2024, 40(24):3601-3605.
刘宇,程路峰,武洋,等.钩藤碱治疗炎症性肠炎可行性及机制研究[J]. 中国药理学通报, 2023, 39(10):1929-1937.
王盟,李慧,吕传峰.钩藤碱固体脂质纳米粒抑制哮喘模型小鼠气道平滑肌细胞增殖的作用机制[J]. 中国药房, 2023, 34(9):1066-1070.
李超,蔺琳,张蕾,等.钩藤碱增强自噬改善TNF-α介导的血管内皮细胞血栓前状态的研究[J]. 中草药,2017, 48(24):5224-5229.
Zheng M Z, Chen M H, Liu C M, et al. Alkaloids extracted from Uncaria rhynchophylla demonstrate neuroprotective effects in MPTP-induced experimental Parkinsonism by regulating the PI3K/Akt/mTOR signaling pathway[J]. J Ethnopharmacol, 2021, 266:113451.
Kuang Y, Zhu M Y, Gu H T, et al. Alkaloids in Uncaria rhynchophylla improves AD pathology by restraining CD4+T cell-mediated neuroinflammation via inhibition of glycolysis in APP/PS1 mice[J]. J Ethnopharmacol, 2024,331:118273.
宋婷婷.异钩藤碱对血管紧张素Ⅱ诱导大鼠心肌细胞肥大的影响及机制[J]. 山东医药, 2017, 57(38):44-47.
林茂,延沁儒,刘锦帆,等.异钩藤碱对AD模型小鼠学习记忆及海马神经元凋亡的影响[J]. 沈阳药科大学学报, 2022, 39(1):46-51.
雷琦,朱婷鸽,何进伟,等.异钩藤碱对癫痫大鼠SIRT1/p53/caspase-3通路及海马神经元凋亡的影响[J]. 中国免疫学杂志, 2022, 38(18):2205-2208.
徐利,李莹莹,张锦军,等.毛钩藤碱对6-羟基多巴胺诱导的帕金森病模型大鼠神经保护作用及机制研究[J]. 沈阳药科大学学报, 2023, 40(5):613-619.
李亚威,谢磊,王娜.毛钩藤碱对人宫颈癌Ca Ski细胞增殖、凋亡、转移及侵袭的影响[J]. 中国实验方剂学杂志, 2022, 28(4):109-115.
Zhang X Y, Wang S, Shu L X, et al. Rapid screening of hepatotoxic components in Uncariae Ramulus Cum Uncis based on“component-target-pathway” network[J]. J Pharm Biomed Anal, 2022, 219:114968.
孙婷,刘伟杰.天麻钩藤的益智作用研究及机制探讨[J]. 中药药理与临床, 2017, 33(3):117-120.
原铁,郭永宁,蔡海荣,等.天麻钩藤饮对脑出血大鼠TLR4、NF-κB和IL-1β表达的影响[J]. 动物医学进展,2018, 39(12):161-164.
彭伟,张立娟,张倩,等.天麻钩藤饮对帕金森病模型大鼠纹状体α-突触核蛋白含量及自噬相关蛋白Beclin1、LC3B表达的影响[J]. 中医杂志, 2018,59(14):1228-1231.
石立业,高超,马彩云,等.羚角钩藤汤控制小儿惊厥发作的临床效果及药理作用研究[J]. 中华中医药杂志, 2019, 34(8):3885-3888.
曾勇,谭超,唐陆军,等.复方钩藤降压片对SHR心肌IL-6及MMP-9表达的影响[J]. 中华中医药学刊,2018, 36(10):2358-2361.
汪学军,何杏玲,卢杏娟,等.天麻钩藤饮对自发性高血压大鼠血清Ca2+浓度及血管平滑肌细胞钙通道的影响[J]. 中国中医基础医学杂志, 2011, 17(11):1217-1219.
崔鑫,李薇,王春萍,等.天麻钩藤颗粒治疗原发性高血压的成本效果分析[J]. 药物评价研究, 2023, 46(9):1970-1976.
金力荣,陈桂英,张春霞,等.天麻钩藤饮加减治疗重度子痫前期的临床评价[J]. 中国实验方剂学杂志,2013, 19(17):313-316.
唐庆,马晓芳,赵桂香,等.天麻钩藤降压胶囊降压及镇静作用研究[J]. 中国实验方剂学杂志, 2012, 18(17):241-243.
Jiang S, Yang X R, Wang Z B, et al. Biotransformation and pharmacokinetic studies of four alkaloids from Uncaria rhynchophylla in rat plasma by ultra-performance liquid chromatography with tandem mass spectrometry[J]. J Pharm Biomed Anal, 2022, 218:114858.)