Article(id=1304388221404737936, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304388157621948709, articleNumber=null, orderNo=null, doi=10.7501/j.issn.0253-2670.2026.15.017, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1770048000000, receivedDateStr=2026-02-03, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788919986343, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788919986343, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788919986343, creator=13701087609, updateTime=1788919986343, updator=13701087609, issue=Issue{id=1304388157621948709, tenantId=1146029695717560320, journalId=1302319053441957962, year='2026', volume='57', issue='15', pageStart='5789', pageEnd='6208', issueExtLink='null', onlineDate='null', pubDate='1786464000000', pubDateStr='2026-08-12', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=1, specialIssue=null, createTime=1788919971137, creator='13701087609', updateTime=1788923514106, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304403017982300207, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304388157621948709, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304403017982300208, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304388157621948709, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=5982, endPage=5998, ext={EN=ArticleExt(id=1304388223317340563, articleId=1304388221404737936, tenantId=1146029695717560320, journalId=1302319053441957962, language=EN, title=Comparative study on international patent layout and technological competition trends of traditional Chinese medicine: An empirical analysis based on five countries, columnId=null, journalTitle=Chinese Traditional and Herbal Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective This study aims to systematically analyze the intellectual property landscape of traditional Chinese medicine (TCM) globally, with a focus on comparing the patent layout characteristics and competitive dynamics in five key countries: China, the United States, Japan, South Korea, and Germany. The goal is to provide strategic references for promoting the high-quality development and internationalization of China's TCM industry. Methods Leveraging the Patyee database, this research retrieved and obtained TCM-related patent data globally and from the aforementioned five countries. Employing a combination of quantitative and qualitative analysis methods, an in-depth examination was conducted from multiple dimensions, including patent application trends, geographical distribution, applicant types, core technological topics, and international layout strategies. Results The research findings indicate that despite a vast number of domestic TCM patent applications (approximately 360 000), the proportion of international applications filed via the Patent Cooperation Treaty (PCT) is relatively low (only 1.37%), revealing a significant deficiency in overseas layout. Regarding the distribution of technological topics, patents related to TCM quality control and standardization technologies are relatively scarce globally (including in China), leaving a gap in meeting the high standards of quality controllability required for modern industrialization and internationalization. In terms of applicant types, 44% of TCM patents in China are held by individuals, while enterprises account for only 34%, reflecting a pattern of individual-led inheritance with enterprise-driven R&D yet to be enhanced. In contrast, TCM-related patent activities in the United States, Japan, and Germany are predominantly driven by multinational pharmaceutical companies or consumer goods giants with complete industrial chains. Conclusion To achieve high-quality internationalization of TCM intellectual property, China urgently needs to establish a systematic overseas patent layout strategy, forming a patent protection system covering the entire industrial chain of R&D, quality control, production, and marketing. The core task is to transform domestic technological advantages into internationally recognized technical standards and to promote the transformation of TCM from a traditional empirical model to a modern, evidence-based innovation paradigm by strengthening collaborative innovation among industry, academia, research, and users., authors=ZHANG Xinyuan, HANG Huojian, GUO Bochi, WU Lingyan, TENG Shuangshuang, SHU Yachun, authorsList=ZHANG Xinyuan, HANG Huojian, GUO Bochi, WU Lingyan, TENG Shuangshuang, SHU Yachun, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1304388221643813265, articleId=1304388221404737936, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=中药专利国际布局与技术竞争态势比较研究:基于5个国家的实证考察, columnId=1304140194819629763, journalTitle=中草药, columnName=数据挖掘与循证医学, runingTitle=null, highlight=null, articleAbstract=目的 系统剖析全球中药领域的知识产权格局,重点比较中国、美国、日本、韩国及德国5个国家的专利布局特征与竞争态势,进而为促进我国中药产业的高质量发展与国际化进程提供策略参考。方法 依托壹专利(Patyee)数据库,检索并获取全球及上述5国的中药相关专利数据。综合运用定量与定性分析方法,从专利申请趋势、地域分布、申请主体构成、核心技术主题聚焦以及跨国布局策略等多个维度进行深入剖析。结果 尽管国内中药专利申请总量庞大(约36万件),但通过《专利合作条约》(Patent Cooperation Treaty,PCT)途径提交的国际专利申请占比较低(仅1.37%),海外布局明显不足。从技术主题分布看,全球范围内(包括中国)涉及中药质量检测与标准化技术的专利均相对稀缺,匹配现代产业化与国际化对质量可控性的高标准需求还有差距。在申请主体方面,中国44%的中药专利由个人持有,企业作为申请主体的占比仅为34%,个人化传承为主、企业化研发有待提升;相比之下,美国、日本、德国的中药相关专利主要由具备完整产业链的跨国制药企业或日化巨头主导。结论 为实现中药知识产权的高质量国际化发展,中国亟待构建系统化的海外专利布局战略,形成覆盖研发、质控、生产与营销的全产业链专利保护体系。核心任务在于将国内的技术积累优势转化为国际认可的技术标准,并通过强化产学研用各主体间的协同创新,推动中医药从传统经验模式向现代循证创新范式转型。, authors=张馨元1, 杭火娟1, 郭泊池2, 吴玲燕2, 滕爽爽2, 束雅春1,3, authorsList=张馨元, 杭火娟, 郭泊池, 吴玲燕, 滕爽爽, 束雅春, authorCompany=1 南京中医药大学附属医院/江苏省中医院, 江苏 南京 210029;
2 南京奥凯知识产权服务有限公司, 江苏 南京 210000;
3 江苏省海滨康复医院, 江苏 连云港 222042, correspAuthors=束雅春, authorNote=张馨元: 张馨元(1998—),女,硕士研究生,研究方向为中药学专业药事管理。Tel:13952159967 E-mail:zxyuan218@163.com, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=71riDFvuFLt697dYOJq/5Q==, pdfFileSize=1819782, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=江苏省知识产权高价值专利培育项目 (GJ20231160_01); 南京市知识产权强链项目 (K2022q03))}, authors=[Author(id=1307423881313149439, tenantId=1146029695717560320, journalId=null, articleId=1304388221404737936, orderNo=null, firstName=null, middleName=null, lastName=null, nameCn=null, orcid=null, stid=null, country=null, authorPic=null, dead=null, email=null, emailSecond=null, emailThird=null, correspondingAuthor=null, authorType=null, ext={}, companyList=null)], 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格日勒, 元文君, 付微, 等. 德国植物药在我国的发展情况及我国中药国际化发展的思考[J]. 亚太传统医药, 2024, 20(4): 1-5.
李国强. 中药国际化现状与发展对策[J]. 今日财富:中国知识产权, 2022, (12): 10-12.
王梦昕, 刘国秀, 史楠楠, 等. 我国中药产品对美出口贸易现状分析及发展战略思考[J]. 世界中医药, 2021, 16(7): 1166-1171.
贺立泽, 王佩贤, 王伟. 德国植物药行业发展探析[J]. 亚太传统医药, 2007, 3(11): 20-22.
拜耳健康消费品中国副总裁黄新峰专访: 拜耳借力整合升级OTC营销渠道[J]. 中国药店, 2016(11): 97.
李莹辉, 李洋, 陈晓雨, 等. 德国典型植物药专利保护策略及启示[J]. 中草药, 2017, 48(7): 1466-1472.
Yang X J, Pei X H. Value and influencing factors of valid Traditional Chinese Medicine compound prescription patents for mammary gland hyperplasia [J]. J Tradit Chin Med, 2022, 42(6): 1012-1018.
张婧悦, 魏曦, 何文静, 等. 中药材大品种专利及创新趋势分析[J]. 中国新药杂志, 2025, 34(10): 1009-1016.
Ikonomopoulou M P, Anderluh G, Coskun S, et al. Patentability of natural products from venomous organisms: A guide for life science researchers [J]. Toxicon, 2026, 269: 108927.
孙林林. 最高法同日公开审理两起涉中药专利侵权上诉案: 聚焦中药标准专利、基因专利侵权司法认定[N]. 人民法院报, 2026-04-24(001).
巩瑞娟, 何照楠, 洪峰, 等. 我国中医药高校科研投入与专利产出现状及相关性分析[J]. 中国现代中药, 2020, 22(6): 840-844.
谢裕颖, 单乐天, 单臻, 等. 浙江省中药创新发展与专利保护现状研究[J]. 中国发明与专利, 2025, 22(9): 80-88.
Zhang B, Pei W J, Cai P P, et al. Recent advances in Chinese patent medicines entering the international market [J]. Drug Discov Ther, 2022, 16(6): 258-272.
许龙, 徐敢, 沈晶晶. 中日韩中药专利申请与授权现状对比研究[J]. 中国药业, 2024, 33(22): 1-7.
Liu P, Fang R, He J W, et al. Patents research and development prospects of spleen-invigorating health food with the homology of medicine and food from 2000 to 2022: A bibliometric analysis [J]. Digit Chin Med, 2023, 6(3): 357-368.
Liu H B, Wang Y F, Huang J L, et al. Analysis on patents of health care products with substances of medicine food homology in China [J]. Chin Herb Med, 2024, 16(3): 412-421.
Zhang X Y, You B H, Li M Q, et al. Analysis of hot spots and innovation development trend of traditional Chinese medicine industry based on patent information mining [A] // Proceedings of the 20255th International Conference on Big Data, Artificial Intelligence and Risk Management [C]. Dongguan: ACM, 2025: 595-601.
Wang X S, Chan A W. Challenges and patenting strategies for Chinese herbal medicine [J]. Chin Med, 2010, 5(1): 24.)
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中草药 | 数据挖掘与循证医学 2026,57(15): 5982-5998
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中草药 |数据挖掘与循证医学 2026 , 57 (15) : 5982 -5998
中药专利国际布局与技术竞争态势比较研究:基于5个国家的实证考察
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作者信息
通讯作者:
束雅春
作者简介:
张馨元: 张馨元(1998—),女,硕士研究生,研究方向为中药学专业药事管理。Tel:13952159967 E-mail:zxyuan218@163.com
Comparative study on international patent layout and technological competition trends of traditional Chinese medicine: An empirical analysis based on five countries
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doi: 10.7501/j.issn.0253-2670.2026.15.017
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目的 系统剖析全球中药领域的知识产权格局,重点比较中国、美国、日本、韩国及德国5个国家的专利布局特征与竞争态势,进而为促进我国中药产业的高质量发展与国际化进程提供策略参考。方法 依托壹专利(Patyee)数据库,检索并获取全球及上述5国的中药相关专利数据。综合运用定量与定性分析方法,从专利申请趋势、地域分布、申请主体构成、核心技术主题聚焦以及跨国布局策略等多个维度进行深入剖析。结果 尽管国内中药专利申请总量庞大(约36万件),但通过《专利合作条约》(Patent Cooperation Treaty,PCT)途径提交的国际专利申请占比较低(仅1.37%),海外布局明显不足。从技术主题分布看,全球范围内(包括中国)涉及中药质量检测与标准化技术的专利均相对稀缺,匹配现代产业化与国际化对质量可控性的高标准需求还有差距。在申请主体方面,中国44%的中药专利由个人持有,企业作为申请主体的占比仅为34%,个人化传承为主、企业化研发有待提升;相比之下,美国、日本、德国的中药相关专利主要由具备完整产业链的跨国制药企业或日化巨头主导。结论 为实现中药知识产权的高质量国际化发展,中国亟待构建系统化的海外专利布局战略,形成覆盖研发、质控、生产与营销的全产业链专利保护体系。核心任务在于将国内的技术积累优势转化为国际认可的技术标准,并通过强化产学研用各主体间的协同创新,推动中医药从传统经验模式向现代循证创新范式转型。
中药  /  知识产权  /  国际化  /  专利分析  /  可视化
Objective This study aims to systematically analyze the intellectual property landscape of traditional Chinese medicine (TCM) globally, with a focus on comparing the patent layout characteristics and competitive dynamics in five key countries: China, the United States, Japan, South Korea, and Germany. The goal is to provide strategic references for promoting the high-quality development and internationalization of China's TCM industry. Methods Leveraging the Patyee database, this research retrieved and obtained TCM-related patent data globally and from the aforementioned five countries. Employing a combination of quantitative and qualitative analysis methods, an in-depth examination was conducted from multiple dimensions, including patent application trends, geographical distribution, applicant types, core technological topics, and international layout strategies. Results The research findings indicate that despite a vast number of domestic TCM patent applications (approximately 360 000), the proportion of international applications filed via the Patent Cooperation Treaty (PCT) is relatively low (only 1.37%), revealing a significant deficiency in overseas layout. Regarding the distribution of technological topics, patents related to TCM quality control and standardization technologies are relatively scarce globally (including in China), leaving a gap in meeting the high standards of quality controllability required for modern industrialization and internationalization. In terms of applicant types, 44% of TCM patents in China are held by individuals, while enterprises account for only 34%, reflecting a pattern of individual-led inheritance with enterprise-driven R&D yet to be enhanced. In contrast, TCM-related patent activities in the United States, Japan, and Germany are predominantly driven by multinational pharmaceutical companies or consumer goods giants with complete industrial chains. Conclusion To achieve high-quality internationalization of TCM intellectual property, China urgently needs to establish a systematic overseas patent layout strategy, forming a patent protection system covering the entire industrial chain of R&D, quality control, production, and marketing. The core task is to transform domestic technological advantages into internationally recognized technical standards and to promote the transformation of TCM from a traditional empirical model to a modern, evidence-based innovation paradigm by strengthening collaborative innovation among industry, academia, research, and users.
traditional Chinese medicine  /  intellectual property  /  internationalization  /  patent analysis  /  visualization
张馨元, 杭火娟, 郭泊池, 吴玲燕, 滕爽爽, 束雅春. 中药专利国际布局与技术竞争态势比较研究:基于5个国家的实证考察. 中草药, 2026 , 57 (15) : 5982 -5998 . DOI: 10.7501/j.issn.0253-2670.2026.15.017
ZHANG Xinyuan, HANG Huojian, GUO Bochi, WU Lingyan, TENG Shuangshuang, SHU Yachun. Comparative study on international patent layout and technological competition trends of traditional Chinese medicine: An empirical analysis based on five countries[J]. Chinese Traditional and Herbal Drugs, 2026 , 57 (15) : 5982 -5998 . DOI: 10.7501/j.issn.0253-2670.2026.15.017

    江苏省知识产权高价值专利培育项目 (GJ20231160_01); 南京市知识产权强链项目 (K2022q03)

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孙娟, 董丽, 曹志华. 国外企业医药专利战略特点及启示[J]. 求医问药: 学术版, 2012, 10(11): 256-257.
格日勒, 元文君, 付微, 等. 德国植物药在我国的发展情况及我国中药国际化发展的思考[J]. 亚太传统医药, 2024, 20(4): 1-5.
李国强. 中药国际化现状与发展对策[J]. 今日财富:中国知识产权, 2022, (12): 10-12.
王梦昕, 刘国秀, 史楠楠, 等. 我国中药产品对美出口贸易现状分析及发展战略思考[J]. 世界中医药, 2021, 16(7): 1166-1171.
贺立泽, 王佩贤, 王伟. 德国植物药行业发展探析[J]. 亚太传统医药, 2007, 3(11): 20-22.
拜耳健康消费品中国副总裁黄新峰专访: 拜耳借力整合升级OTC营销渠道[J]. 中国药店, 2016(11): 97.
李莹辉, 李洋, 陈晓雨, 等. 德国典型植物药专利保护策略及启示[J]. 中草药, 2017, 48(7): 1466-1472.
Yang X J, Pei X H. Value and influencing factors of valid Traditional Chinese Medicine compound prescription patents for mammary gland hyperplasia [J]. J Tradit Chin Med, 2022, 42(6): 1012-1018.
张婧悦, 魏曦, 何文静, 等. 中药材大品种专利及创新趋势分析[J]. 中国新药杂志, 2025, 34(10): 1009-1016.
Ikonomopoulou M P, Anderluh G, Coskun S, et al. Patentability of natural products from venomous organisms: A guide for life science researchers [J]. Toxicon, 2026, 269: 108927.
孙林林. 最高法同日公开审理两起涉中药专利侵权上诉案: 聚焦中药标准专利、基因专利侵权司法认定[N]. 人民法院报, 2026-04-24(001).
巩瑞娟, 何照楠, 洪峰, 等. 我国中医药高校科研投入与专利产出现状及相关性分析[J]. 中国现代中药, 2020, 22(6): 840-844.
谢裕颖, 单乐天, 单臻, 等. 浙江省中药创新发展与专利保护现状研究[J]. 中国发明与专利, 2025, 22(9): 80-88.
Zhang B, Pei W J, Cai P P, et al. Recent advances in Chinese patent medicines entering the international market [J]. Drug Discov Ther, 2022, 16(6): 258-272.
许龙, 徐敢, 沈晶晶. 中日韩中药专利申请与授权现状对比研究[J]. 中国药业, 2024, 33(22): 1-7.
Liu P, Fang R, He J W, et al. Patents research and development prospects of spleen-invigorating health food with the homology of medicine and food from 2000 to 2022: A bibliometric analysis [J]. Digit Chin Med, 2023, 6(3): 357-368.
Liu H B, Wang Y F, Huang J L, et al. Analysis on patents of health care products with substances of medicine food homology in China [J]. Chin Herb Med, 2024, 16(3): 412-421.
Zhang X Y, You B H, Li M Q, et al. Analysis of hot spots and innovation development trend of traditional Chinese medicine industry based on patent information mining [A] // Proceedings of the 20255th International Conference on Big Data, Artificial Intelligence and Risk Management [C]. Dongguan: ACM, 2025: 595-601.
Wang X S, Chan A W. Challenges and patenting strategies for Chinese herbal medicine [J]. Chin Med, 2010, 5(1): 24.
2026年第57卷第15期
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doi: 10.7501/j.issn.0253-2670.2026.15.017
  • 接收时间:2026-02-03
  • 首发时间:2026-09-09
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2种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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