Article(id=1304415552164881007, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304415531491152712, articleNumber=null, orderNo=null, doi=10.7501/j.issn.0253-2670.2026.09.009, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1765814400000, receivedDateStr=2025-12-16, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788926502505, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788926502505, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788926502505, creator=13701087609, updateTime=1788926502505, updator=13701087609, issue=Issue{id=1304415531491152712, tenantId=1146029695717560320, journalId=1302319053441957962, year='2026', volume='57', issue='9', pageStart='3261', pageEnd='3684', issueExtLink='null', onlineDate='null', pubDate='1778515200000', pubDateStr='2026-05-12', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788926497576, creator='13701087609', updateTime=1788926796984, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304416787358049066, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304415531491152712, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304416787358049067, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304415531491152712, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=3353, endPage=3364, ext={EN=ArticleExt(id=1304415554157175409, articleId=1304415552164881007, tenantId=1146029695717560320, journalId=1302319053441957962, language=EN, title=Comparative analysis of Lonicerae Japonicae Flos quality using smart sensory technology and multi-component content analysis across different drying methods, columnId=null, journalTitle=Chinese Traditional and Herbal Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective To compare the levels of multiple components (phenolic acids and luteolin glycoside) in Jinyinhua (Lonicerae Japonicae Flos, LJF), along with changes in “colour, aroma and flavor”, under different drying methods to determine the optimal drying technique. Methods Quality control of phenolic acids and luteoloside in LJF was conducted using HPLC technology. Intelligent sensory technology was employed to study the color, aroma, and taste characteristics of LJF under different drying methods. The quality of LJF processed with various drying techniques was evaluated through correlation analysis of color-aroma-taste and multiple indicator components. Results Steam-blanched drying, freeze-vacuum drying, and microwave-blanched drying resulted in higher total phenolic acid content, while sun-drying, microwave-blanched drying, and steam-blanched drying yielded higher luteoloside levels. The differences in color-aroma-taste profiles of LJF under different drying methods were reflected in brightness (L*), red-green chromaticity (a*), and responses from W5S, W1W, W1S, W2S, W2W sensors, along with bitterness and astringency. Correlation analysis revealed that higher total phenolic acids correlated with darker green coloration, elevated W1W sensor responses, intensified astringency, and reduced bitterness. Conversely, increased luteoloside content was associated with higher brightness and diminished responses from W5S and W1W sensors. Freeze-vacuum drying produced optimal color, shade-drying achieved the most pronounced aroma, while steam-blanched and microwave-blanched drying generated distinctive bitter and astringent aftertastes. Conclusion From the perspectives of multi-component retention, chromatic characteristics, and taste profile, steam-blanched drying and microwave-blanched drying have been identified as the optimal drying processing methods for LJF. This study provides a novel methodology for optimizing drying techniques and enabling rapid quality assessment of LJF., authors=SUN Mingyue, JIANG Xiaoya, ZOU Han, CHENG Hua, WU Moguang, FENG Yu, NIU Liying, authorsList=SUN Mingyue, JIANG Xiaoya, ZOU Han, CHENG Hua, WU Moguang, FENG Yu, NIU Liying, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1304415554052317808, articleId=1304415552164881007, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=智能感官技术与多成分定量联合分析比较不同干燥方式金银花质量, columnId=1304140189132149234, journalTitle=中草药, columnName=药剂与工艺, runingTitle=null, highlight=null, articleAbstract=目的 比较不同干燥方式下金银花Lonicerae Japonicae Flos中的多指标成分(酚酸类成分和木犀草苷)含量及“色、气、味”的变化,获得最佳的干燥方式。方法 通过HPLC技术对金银花中酚酸类成分和木犀草苷进行质量控制,利用智能感官技术研究不同干燥方式下金银花的色、气、味特征,通过色-气-味-多指标成分相关性分析,评价不同干燥方式金银花的质量。结果 蒸汽杀青烘干、冷冻真空干燥、微波杀青烘干的总酚酸含量较高;晒干、微波杀青烘干、蒸汽杀青烘干的木犀草苷含量较高。不同干燥方式的金银花“色、气、味”差异体现在亮度值(L*)、红绿色度值(a*)、W5S、W1W、W1S、W2S、W2W号传感器、苦味、涩味。经相关性分析,酚酸类成分总含量越高,金银花绿色越深、W1W号传感器响应值越高、涩味越大、苦味越小;木犀草苷含量越高,金银花亮度越高、W5S、W1W号等传感器响应值越低。真空冷冻色泽最佳,阴干的气味最浓郁,而经蒸汽杀青烘干、微波杀青烘干的金银花体现出独有的苦味回味、涩味回味。结论 从多指标成分保留、色度、味道角度来看,蒸汽杀青烘干、微波杀青烘干为金银花最佳的干燥方式,为金银花干燥工艺优化和质量快速评价提供新方法。, authors=孙名悦1, 姜晓娅1,2,3, 邹涵1, 程华4,5, 武墨广6, 冯玉1,2,3, 牛丽颖1,2,3, authorsList=孙名悦, 姜晓娅, 邹涵, 程华, 武墨广, 冯玉, 牛丽颖, authorCompany=1 河北中医药大学, 河北 石家庄 050200;
2 河北省中药配方颗粒技术创新中心, 河北 石家庄 050091;
3 中药材品质评价与标准化河北省工程研究中心, 河北 石家庄 050091;
4 河北省科学院生物研究所, 河北 石家庄 050081;
5 河北省巨鹿县应用技术研究院, 河北 邢台 055250;
6 河北省巨鹿县农业农村局, 河北 邢台 055250, correspAuthors=冯玉, authorNote=孙名悦: 孙名悦(1999-),硕士研究生,研究方向为中药分析。E-mail:yjs20234012@hebcm.edu.cn, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=BM6yaipIBRAcPhdqbnv/EQ==, pdfFileSize=1632553, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=合肥综合性国家科学中心大健康研究院新安医学与中医药现代化研究所“揭榜挂帅”项目(2023CXMMTCM014);安徽省自然基金项目(2408085MH229);安徽省科技重大专项项目(202203a07020031))}, authors=null, keywords=[Keyword(id=1304415554480136818, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415552164881007, language=CN, orderNo=1, keyword=金银花), Keyword(id=1304415554559828595, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304415552164881007, language=CN, orderNo=2, 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赵琳琳,赵云平,魏静娜,等.金银花化学成分、药理作用研究进展及质量标志物的预测分析[J].中国现代医药杂志, 2025, 27(4):35-40.
刘畅,周枝,尹志刚,等.基于网络药理学和分子对接技术探究金银花入血成分干预新型冠状病毒肺炎的作用机制[J].现代药物与临床, 2022, 37(2):264-274.
龚婕,姚芙,厉晓,等.基于HPLC指纹图谱和多成分定量结合化学模式识别的白薇质量评价[J].中草药,2025, 56(15):5578-5585.
郝培君,张林祥,靳婉君,等.基于HPLC指纹图谱与指标性成分结合多元统计学对色选金银花等级的评价研究[J].中国现代应用药学, 2023, 40(19):2694-2701.
罗雨婷,陈雪梅,卢晓梅,等.基于智能感官技术及BP神经网络的制枳壳饮片发酵程度快速判别研究[J].中草药, 2025, 56(4):1159-1170.
奉梅,徐杨,时小东,等.基于电子舌技术研究蜜炙枇杷叶配方颗粒的“炮制痕迹”[J].中草药, 2024, 55(6):1970-1976.
吴鑫雨,邱丽媛,王又迪,等.基于智能感官与多源信息融合技术的香附炮制程度快速辨识方法研究[J].中草药, 2023, 54(21):7007-7016.
朱田田,张菁,晋玲,等.基于智能感官技术与化学计量学比较不同采收季节肉苁蓉的品质[J].中草药,2025, 56(19):7168-7177.
孙怀竹,梁金玲,许天阳,等.干燥对不同药用部位中草药化学成分影响的研究进展[J].中华中医药学刊,2025, 43(2):246-250.
熊乐文,黄文静,张龙霏,等.干燥方式对金银花酚酸类和黄酮类成分的影响[J].中华中医药杂志, 2024,39(5):2444-2450.
章丽,及华,李洪涛,等.金银花初加工技术研究进展[J].河北农业科学, 2023, 27(4):91-95.
孙洁,王晓,周洁,等.变温干燥对良种金银花活性成分含量的影响[J].中华中医药杂志, 2014, 29(10):3302-3305.
马涵玉,钱琪,王凤霞,等.基于HS-GC-MS和电子感官技术比较不同产地金银花气味和味道差异[J].中草药, 2024, 55(6):2085-2093.
刘璐,吕凌,李晨,等.基于多指标成分和模式识别分析不同产地金银花的质量差异[J].中华中医药杂志,2023, 38(9):4328-4335.
曲珍妮,吕畅,毕钰,等.基于电子仿生感官技术的山楂不同炮制品颜色、味道变化研究[J].中草药, 2024,55(20):6929-6939.
熊乐文,金莹,黄玮慕,等.金银花色泽与酚酸类成分含量相关性研究[J].中成药, 2022, 44(8):2736-2739.
陆远,张研,王莹,等.金银花化学成分及其抗氧化活性研究[J].中成药, 2024, 46(8):2638-2644.
王淑,张翠翠,郭凤丹,等.基于UPLC多指标含量测定和指纹图谱的不同种质金银花药材质量评价研究[J].中草药, 2024, 55(3):947-955.
熊乐文,金莹,王彦予,等.金银花酚酸类化学成分、药理活性及体内代谢研究进展[J].中成药, 2022,44(3):864-871.
马芹,赵慧,刘振华,等.金银花挥发性成分研究进展[J].中华中医药杂志, 2024, 39(10):5397-5401.
范天慈,窦志英,李捷,等.不同干燥方式对中药成分影响的研究进展[J].中国现代中药, 2021, 23(11):2017-2024.
韩雪,郑玉,谢兴亮,等.中药多酚涩味的内涵认识与掩蔽方法研究进展[J].中国中药杂志, 2022, 47(20):5443-5451.
李倩,陈燕,窦霞,等.基于“谱-效”关系的金银花成分及抑菌活性研究[J].时珍国医国药, 2023, 34(9):2103-2108.
贾莉洁,曲夷.《神农本草经》苦味利水药在经方中的应用[J].山东中医杂志, 2025, 44(5):516-521.)
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中草药 |药剂与工艺 2026 , 57 (9) : 3353 -3364
智能感官技术与多成分定量联合分析比较不同干燥方式金银花质量
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孙名悦1, 姜晓娅1,2,3, 邹涵1, 程华4,5, 武墨广6, 冯玉1,2,3, 牛丽颖1,2,3
作者信息
    1 河北中医药大学, 河北 石家庄 050200;
    2 河北省中药配方颗粒技术创新中心, 河北 石家庄 050091;
    3 中药材品质评价与标准化河北省工程研究中心, 河北 石家庄 050091;
    4 河北省科学院生物研究所, 河北 石家庄 050081;
    5 河北省巨鹿县应用技术研究院, 河北 邢台 055250;
    6 河北省巨鹿县农业农村局, 河北 邢台 055250
通讯作者:
冯玉
作者简介:
孙名悦: 孙名悦(1999-),硕士研究生,研究方向为中药分析。E-mail:yjs20234012@hebcm.edu.cn
Comparative analysis of Lonicerae Japonicae Flos quality using smart sensory technology and multi-component content analysis across different drying methods
  • SUN Mingyue, JIANG Xiaoya, ZOU Han, CHENG Hua, WU Moguang, FENG Yu, NIU Liying
  • Affiliations
    doi: 10.7501/j.issn.0253-2670.2026.09.009
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    目的 比较不同干燥方式下金银花Lonicerae Japonicae Flos中的多指标成分(酚酸类成分和木犀草苷)含量及“色、气、味”的变化,获得最佳的干燥方式。方法 通过HPLC技术对金银花中酚酸类成分和木犀草苷进行质量控制,利用智能感官技术研究不同干燥方式下金银花的色、气、味特征,通过色-气-味-多指标成分相关性分析,评价不同干燥方式金银花的质量。结果 蒸汽杀青烘干、冷冻真空干燥、微波杀青烘干的总酚酸含量较高;晒干、微波杀青烘干、蒸汽杀青烘干的木犀草苷含量较高。不同干燥方式的金银花“色、气、味”差异体现在亮度值(L*)、红绿色度值(a*)、W5S、W1W、W1S、W2S、W2W号传感器、苦味、涩味。经相关性分析,酚酸类成分总含量越高,金银花绿色越深、W1W号传感器响应值越高、涩味越大、苦味越小;木犀草苷含量越高,金银花亮度越高、W5S、W1W号等传感器响应值越低。真空冷冻色泽最佳,阴干的气味最浓郁,而经蒸汽杀青烘干、微波杀青烘干的金银花体现出独有的苦味回味、涩味回味。结论 从多指标成分保留、色度、味道角度来看,蒸汽杀青烘干、微波杀青烘干为金银花最佳的干燥方式,为金银花干燥工艺优化和质量快速评价提供新方法。
    金银花  /  干燥方式  /  电子眼  /  电子鼻  /  电子舌  /  质量评价  /  蒸汽杀青烘干  /  微波杀青烘干
    Objective To compare the levels of multiple components (phenolic acids and luteolin glycoside) in Jinyinhua (Lonicerae Japonicae Flos, LJF), along with changes in “colour, aroma and flavor”, under different drying methods to determine the optimal drying technique. Methods Quality control of phenolic acids and luteoloside in LJF was conducted using HPLC technology. Intelligent sensory technology was employed to study the color, aroma, and taste characteristics of LJF under different drying methods. The quality of LJF processed with various drying techniques was evaluated through correlation analysis of color-aroma-taste and multiple indicator components. Results Steam-blanched drying, freeze-vacuum drying, and microwave-blanched drying resulted in higher total phenolic acid content, while sun-drying, microwave-blanched drying, and steam-blanched drying yielded higher luteoloside levels. The differences in color-aroma-taste profiles of LJF under different drying methods were reflected in brightness (L*), red-green chromaticity (a*), and responses from W5S, W1W, W1S, W2S, W2W sensors, along with bitterness and astringency. Correlation analysis revealed that higher total phenolic acids correlated with darker green coloration, elevated W1W sensor responses, intensified astringency, and reduced bitterness. Conversely, increased luteoloside content was associated with higher brightness and diminished responses from W5S and W1W sensors. Freeze-vacuum drying produced optimal color, shade-drying achieved the most pronounced aroma, while steam-blanched and microwave-blanched drying generated distinctive bitter and astringent aftertastes. Conclusion From the perspectives of multi-component retention, chromatic characteristics, and taste profile, steam-blanched drying and microwave-blanched drying have been identified as the optimal drying processing methods for LJF. This study provides a novel methodology for optimizing drying techniques and enabling rapid quality assessment of LJF.
    Lonicerae Japonicae Flos  /  drying methods  /  electronic eye  /  electronic nose  /  electronic tongue  /  quality evaluation  /  steam-blanched drying  /  microwave-blanched drying
    孙名悦, 姜晓娅, 邹涵, 程华, 武墨广, 冯玉, 牛丽颖. 智能感官技术与多成分定量联合分析比较不同干燥方式金银花质量. 中草药, 2026 , 57 (9) : 3353 -3364 . DOI: 10.7501/j.issn.0253-2670.2026.09.009
    SUN Mingyue, JIANG Xiaoya, ZOU Han, CHENG Hua, WU Moguang, FENG Yu, NIU Liying. Comparative analysis of Lonicerae Japonicae Flos quality using smart sensory technology and multi-component content analysis across different drying methods[J]. Chinese Traditional and Herbal Drugs, 2026 , 57 (9) : 3353 -3364 . DOI: 10.7501/j.issn.0253-2670.2026.09.009

      合肥综合性国家科学中心大健康研究院新安医学与中医药现代化研究所“揭榜挂帅”项目(2023CXMMTCM014);安徽省自然基金项目(2408085MH229);安徽省科技重大专项项目(202203a07020031)

    参考文献 引证文献
    排序方式:
    中国药典[S].一部. 2025:238.
    赵琳琳,赵云平,魏静娜,等.金银花化学成分、药理作用研究进展及质量标志物的预测分析[J].中国现代医药杂志, 2025, 27(4):35-40.
    刘畅,周枝,尹志刚,等.基于网络药理学和分子对接技术探究金银花入血成分干预新型冠状病毒肺炎的作用机制[J].现代药物与临床, 2022, 37(2):264-274.
    龚婕,姚芙,厉晓,等.基于HPLC指纹图谱和多成分定量结合化学模式识别的白薇质量评价[J].中草药,2025, 56(15):5578-5585.
    郝培君,张林祥,靳婉君,等.基于HPLC指纹图谱与指标性成分结合多元统计学对色选金银花等级的评价研究[J].中国现代应用药学, 2023, 40(19):2694-2701.
    罗雨婷,陈雪梅,卢晓梅,等.基于智能感官技术及BP神经网络的制枳壳饮片发酵程度快速判别研究[J].中草药, 2025, 56(4):1159-1170.
    奉梅,徐杨,时小东,等.基于电子舌技术研究蜜炙枇杷叶配方颗粒的“炮制痕迹”[J].中草药, 2024, 55(6):1970-1976.
    吴鑫雨,邱丽媛,王又迪,等.基于智能感官与多源信息融合技术的香附炮制程度快速辨识方法研究[J].中草药, 2023, 54(21):7007-7016.
    朱田田,张菁,晋玲,等.基于智能感官技术与化学计量学比较不同采收季节肉苁蓉的品质[J].中草药,2025, 56(19):7168-7177.
    孙怀竹,梁金玲,许天阳,等.干燥对不同药用部位中草药化学成分影响的研究进展[J].中华中医药学刊,2025, 43(2):246-250.
    熊乐文,黄文静,张龙霏,等.干燥方式对金银花酚酸类和黄酮类成分的影响[J].中华中医药杂志, 2024,39(5):2444-2450.
    章丽,及华,李洪涛,等.金银花初加工技术研究进展[J].河北农业科学, 2023, 27(4):91-95.
    孙洁,王晓,周洁,等.变温干燥对良种金银花活性成分含量的影响[J].中华中医药杂志, 2014, 29(10):3302-3305.
    马涵玉,钱琪,王凤霞,等.基于HS-GC-MS和电子感官技术比较不同产地金银花气味和味道差异[J].中草药, 2024, 55(6):2085-2093.
    刘璐,吕凌,李晨,等.基于多指标成分和模式识别分析不同产地金银花的质量差异[J].中华中医药杂志,2023, 38(9):4328-4335.
    曲珍妮,吕畅,毕钰,等.基于电子仿生感官技术的山楂不同炮制品颜色、味道变化研究[J].中草药, 2024,55(20):6929-6939.
    熊乐文,金莹,黄玮慕,等.金银花色泽与酚酸类成分含量相关性研究[J].中成药, 2022, 44(8):2736-2739.
    陆远,张研,王莹,等.金银花化学成分及其抗氧化活性研究[J].中成药, 2024, 46(8):2638-2644.
    王淑,张翠翠,郭凤丹,等.基于UPLC多指标含量测定和指纹图谱的不同种质金银花药材质量评价研究[J].中草药, 2024, 55(3):947-955.
    熊乐文,金莹,王彦予,等.金银花酚酸类化学成分、药理活性及体内代谢研究进展[J].中成药, 2022,44(3):864-871.
    马芹,赵慧,刘振华,等.金银花挥发性成分研究进展[J].中华中医药杂志, 2024, 39(10):5397-5401.
    范天慈,窦志英,李捷,等.不同干燥方式对中药成分影响的研究进展[J].中国现代中药, 2021, 23(11):2017-2024.
    韩雪,郑玉,谢兴亮,等.中药多酚涩味的内涵认识与掩蔽方法研究进展[J].中国中药杂志, 2022, 47(20):5443-5451.
    李倩,陈燕,窦霞,等.基于“谱-效”关系的金银花成分及抑菌活性研究[J].时珍国医国药, 2023, 34(9):2103-2108.
    贾莉洁,曲夷.《神农本草经》苦味利水药在经方中的应用[J].山东中医杂志, 2025, 44(5):516-521.
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    2种不同金属材料的力学参数

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    小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
    多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
    红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
    小菇属 Mycena 11 5.26
    光柄菇属 Pluteus 5 2.39
    红菇属 Russula 17 8.13
    栓菌属 Trametes 5 2.39
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