中草药

黄酮苷类成分治疗上呼吸道感染的作用机制研究进展

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中草药 | 中医药抗病毒研究 2026,57(8): 2971-2980

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中草药 |中医药抗病毒研究 2026 , 57 (8) : 2971 -2980

黄酮苷类成分治疗上呼吸道感染的作用机制研究进展

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邹维¹, 谢亮², 邱兵², 杨华杰^1,3, 孙江婷¹, 廖曾睿¹, 饶毅^1,3, 吕尚^1,3

作者信息

通讯作者:

吕尚

作者简介:

邹维: 邹维,硕士研究生,研究方向为中药药效物质基础。E-mail:13319353067@163.com

Research progress on mechanism of flavonoid glycosides in treating upper respiratory tract infections

ZOU Wei, XIE Liang, QIU Bing, YANG Huajie, SUN Jiangting, LIAO Zengrui, RAO Yi, LYU Shang

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doi: 10.7501/j.issn.0253-2670.2026.08.010

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摘要

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上呼吸道感染是一类常见急性感染性疾病，其发病群体以免疫力较低者为主，主要由病毒或细菌感染引发。典型症状为鼻塞、咳嗽等局部表现，易向下呼吸道迁延，诱发哮喘、支气管炎、肺炎等并发症，影响患者的健康及生活质量。黄酮苷类化合物是一类广泛存在于中药中的生物活性物质，对上呼吸道感染具有一定的治疗作用，主要通过抑制炎症反应、抑制氧化应激、抗病毒、调节免疫等途径实现治疗上呼吸道感染的目的。通过综述黄酮苷类化合物治疗上呼吸道感染机制的研究进展，为阐明黄酮苷类化合物治疗上呼吸道感染机制及临床运用提供参考。

关键词

上呼吸道感染 / 黄酮苷类成分 / 炎症反应 / 抗病毒 / 免疫调节 / 抗菌

Abstract

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Upper respiratory tract infections (URTI) are common acute infectious diseases, primarily affecting immunocompromised populations, mainly caused by viral or bacterial infections. Typical symptoms include nasal congestion and coughing, which can progress to lower respiratory tract complications such as asthma, bronchitis, and pneumonia, significantly impacting patients’ health and quality of life. Flavonoid glycosides, bioactive compounds widely found in traditional Chinese medicine, exhibit therapeutic effects against URTI through mechanisms including anti-inflammatory action, inhibition of oxidative stress, antiviral activity and immune regulation. This review summarizes recent research progress on the therapeutic mechanisms of flavonoid glycosides for upper respiratory infections, aiming to provide reference for clarifying the mechanism and clinical application of flavonoid glycosides in the treatment of URTI.

Key words

upper respiratory tract infection / flavonoid glycosides / inflammatory response / antiviral / immunoregulation / antibiosis

引用本文

邹维, 谢亮, 邱兵, 杨华杰, 孙江婷, 廖曾睿, 饶毅, 吕尚. 黄酮苷类成分治疗上呼吸道感染的作用机制研究进展. 中草药, 2026 , 57 (8) : 2971 -2980 . DOI: 10.7501/j.issn.0253-2670.2026.08.010

ZOU Wei, XIE Liang, QIU Bing, YANG Huajie, SUN Jiangting, LIAO Zengrui, RAO Yi, LYU Shang. Research progress on mechanism of flavonoid glycosides in treating upper respiratory tract infections[J]. Chinese Traditional and Herbal Drugs, 2026 , 57 (8) : 2971 -2980 . DOI: 10.7501/j.issn.0253-2670.2026.08.010

基金

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国家自然科学基金资助项目 (82560758); 国家自然科学基金资助项目 (82204590); 江西省自然科学基金资助项目 (20252BAC240467,20224BAB216099); 中国博士后科学基金第七十三批面上资助 (2023M731439); 江西中医药标准研究中心 (12425013)

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doi: 10.7501/j.issn.0253-2670.2026.08.010

接收时间：2025-10-17
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2种不同金属材料的力学参数

科 Family	属数 Number of genus	种数 Number of species	占总种数比例 Percentage of total species (%)	属 Genus	种数 Number of species	占总种数比例 Percentage of total species (%)
鹅膏菌科Amanitaceae	2	11	5.26	鹅膏菌属 Amanita	10	4.78
小菇科 Mycenaceae	2	12	5.74	丝盖伞属 Inocybe	5	2.39
多孔菌科 Polyporaceae	8	14	6.70	蜡蘑属 Laccaria	5	2.39
红菇科 Russulaceae	3	23	11.00	小皮伞属 Marasmius	6	2.87
				小菇属 Mycena	11	5.26
				光柄菇属 Pluteus	5	2.39
				红菇属 Russula	17	8.13
				栓菌属 Trametes	5	2.39

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