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Its processing began during the Northern and Southern Dynasties, evolving over generations into more than ten methods primarily involving slicing and stir-frying. Among these, Atractylodis Macrocephalae Rhizoma and stir-frying Atractylodis Macrocephalae Rhizoma with honey bran remain in use today. Current quality control for Atractylodis Macrocephalae Rhizoma primarily relies on pharmacopoeia and local standards, employing multi-indicator monitoring. However, these standards predominantly focus on chemical constituents, often detaching from clinical practice. Furthermore, standards for processed slices highly overlap with raw material standards, lacking distinct characteristics for processed forms. This review synthesizes ancient herbal texts, processing treatises, successive editions of pharmacopoeias, regional processing regulations, and modern literature to trace the historical evolution of Atractylodis Macrocephalae Rhizoma processing, quality control standards and technical methodologies of Atractylodis Macrocephalae Rhizoma. It aims to provide theoretical foundations for refining Atractylodis Macrocephalae Rhizoma quality standards and advancing the production of high-quality, efficacious Atractylodis Macrocephalae Rhizoma., authors=ZHANG Xiaochun, QIN Yuwen, SHOU Haiyan, FAN Xinrong, ZHAO Qi, XUE Chang, JIANG Chengxi, CHENG Jinguo, authorsList=ZHANG Xiaochun, QIN Yuwen, SHOU Haiyan, FAN Xinrong, ZHAO Qi, XUE Chang, JIANG Chengxi, CHENG Jinguo, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1304414739552035446, articleId=1304414737769456245, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=白术炮制历史沿革及现代质量控制研究, columnId=1304140194685415572, journalTitle=中草药, columnName=综述, runingTitle=null, highlight=null, articleAbstract=作为大宗常用中药材白术Atractylodis Macrocephalae Rhizoma药用历史久、应用广,具有健脾益气、燥湿利水等作用。其炮制始于南北朝,历经多代形成10余种炮制方法,主要以切制、炒制为主,其中生白术、麸炒白术沿用至今。当前白术药材质量检测依据主要为《中国药典》及地方标准,通过多指标控制质量,但是多以成分指标为主,脱离临床,且饮片标准与药材标准高度重合、缺乏饮片特色。通过综述本草古籍、炮制专著、历版《中国药典》、地方炮规及现代文献,对白术的炮制历史沿革、质量控制标准、质量控制技术手段等进行梳理,为白术质量控制标准的完善及优质优效白术的生产提供理论依据。, authors=张晓淳1, 秦宇雯1, 寿海艳1, 范欣荣2, 赵祺3, 薛畅3, 姜程曦3, 程锦国4, authorsList=张晓淳, 秦宇雯, 寿海艳, 范欣荣, 赵祺, 薛畅, 姜程曦, 程锦国, authorCompany=1 温州医科大学中医药学院, 浙江 温州 325035;
2 浙江中医药大学附属丽水中医院 药剂科, 浙江 丽水 323000;
3 温州医科大学药学院, 浙江 温州 325035;
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白术炮制历史沿革及现代质量控制研究
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中草药 | 综述 2026,57(4): 1538-1545
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中草药 |综述 2026 , 57 (4) : 1538 -1545
白术炮制历史沿革及现代质量控制研究
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张晓淳1, 秦宇雯1, 寿海艳1, 范欣荣2, 赵祺3, 薛畅3, 姜程曦3, 程锦国4
作者信息
    1 温州医科大学中医药学院, 浙江 温州 325035;
    2 浙江中医药大学附属丽水中医院 药剂科, 浙江 丽水 323000;
    3 温州医科大学药学院, 浙江 温州 325035;
    4 温州医科大学附属第一医院, 浙江 温州 325000
通讯作者:
程锦国
作者简介:
张晓淳: 张晓淳,硕士研究生,研究方向中药炮制及中药质量评价。E-mail:zxc1730430607zxc@163.com
Historical development of processing methods and modern quality control research for Atractylodis Macrocephalae Rhizoma
  • ZHANG Xiaochun, QIN Yuwen, SHOU Haiyan, FAN Xinrong, ZHAO Qi, XUE Chang, JIANG Chengxi, CHENG Jinguo
  • Affiliations
    doi: 10.7501/j.issn.0253-2670.2026.04.029
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    作为大宗常用中药材白术Atractylodis Macrocephalae Rhizoma药用历史久、应用广,具有健脾益气、燥湿利水等作用。其炮制始于南北朝,历经多代形成10余种炮制方法,主要以切制、炒制为主,其中生白术、麸炒白术沿用至今。当前白术药材质量检测依据主要为《中国药典》及地方标准,通过多指标控制质量,但是多以成分指标为主,脱离临床,且饮片标准与药材标准高度重合、缺乏饮片特色。通过综述本草古籍、炮制专著、历版《中国药典》、地方炮规及现代文献,对白术的炮制历史沿革、质量控制标准、质量控制技术手段等进行梳理,为白术质量控制标准的完善及优质优效白术的生产提供理论依据。
    白术  /  炮制  /  历史沿革  /  质量标准  /  质量控制技术
    As a commonly used bulk Chinese medicinal herb, Baizhu (Atractylodis Macrocephalae Rhizoma) has a long history of medicinal use and wide application, possessing effects such as strengthening the spleen and boosting qi, drying dampness, and promoting diuresis. Its processing began during the Northern and Southern Dynasties, evolving over generations into more than ten methods primarily involving slicing and stir-frying. Among these, Atractylodis Macrocephalae Rhizoma and stir-frying Atractylodis Macrocephalae Rhizoma with honey bran remain in use today. Current quality control for Atractylodis Macrocephalae Rhizoma primarily relies on pharmacopoeia and local standards, employing multi-indicator monitoring. However, these standards predominantly focus on chemical constituents, often detaching from clinical practice. Furthermore, standards for processed slices highly overlap with raw material standards, lacking distinct characteristics for processed forms. This review synthesizes ancient herbal texts, processing treatises, successive editions of pharmacopoeias, regional processing regulations, and modern literature to trace the historical evolution of Atractylodis Macrocephalae Rhizoma processing, quality control standards and technical methodologies of Atractylodis Macrocephalae Rhizoma. It aims to provide theoretical foundations for refining Atractylodis Macrocephalae Rhizoma quality standards and advancing the production of high-quality, efficacious Atractylodis Macrocephalae Rhizoma.
    Atractylodis Macrocephalae Rhizoma  /  concoctions  /  historical development  /  quality standards  /  quality control techniques
    张晓淳, 秦宇雯, 寿海艳, 范欣荣, 赵祺, 薛畅, 姜程曦, 程锦国. 白术炮制历史沿革及现代质量控制研究. 中草药, 2026 , 57 (4) : 1538 -1545 . DOI: 10.7501/j.issn.0253-2670.2026.04.029
    ZHANG Xiaochun, QIN Yuwen, SHOU Haiyan, FAN Xinrong, ZHAO Qi, XUE Chang, JIANG Chengxi, CHENG Jinguo. Historical development of processing methods and modern quality control research for Atractylodis Macrocephalae Rhizoma[J]. Chinese Traditional and Herbal Drugs, 2026 , 57 (4) : 1538 -1545 . DOI: 10.7501/j.issn.0253-2670.2026.04.029

      温州市重大科技项目攻关“揭榜挂帅”项目 (ZN2023004); 温州医科大学人才科研启动项目 (QTJ23033)

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    2026年第57卷第4期
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    2种不同金属材料的力学参数

    Family
    属数
    Number of
    genus
    种数
    Number of
    species
    占总种数比例
    Percentage of
    total species (%)

    Genus
    种数
    Number of
    species
    占总种数比例
    Percentage of total
    species (%)
    鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
    小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
    多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
    红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
    小菇属 Mycena 11 5.26
    光柄菇属 Pluteus 5 2.39
    红菇属 Russula 17 8.13
    栓菌属 Trametes 5 2.39
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