Article(id=1304414735911375672, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304414700964443026, articleNumber=null, orderNo=null, doi=10.7501/j.issn.0253-2670.2026.04.024, pmid=null, cstr=null, oa=null, hot=0, price=null, onlineType=0, articleFormat=0, articleType=null, articleTypeStr=null, receivedDate=1759334400000, receivedDateStr=2025-10-02, revisedDate=null, revisedDateStr=null, acceptedDate=null, acceptedDateStr=null, onlineDate=1788926307894, onlineDateStr=2026-09-09, pubDate=null, pubDateStr=null, doiRegisterDate=null, doiRegisterDateStr=null, onlineIssueDate=1788926307894, onlineIssueDateStr=2026-09-09, onlineJustAcceptDate=null, onlineJustAcceptDateStr=null, onlineFirstDate=null, onlineFirstDateStr=null, sourceXml=null, magXml=null, createTime=1788926307894, creator=13701087609, updateTime=1788926307894, updator=13701087609, issue=Issue{id=1304414700964443026, tenantId=1146029695717560320, journalId=1302319053441957962, year='2026', volume='57', issue='4', pageStart='1209', pageEnd='1596', issueExtLink='null', onlineDate='null', pubDate='1772208000000', pubDateStr='2026-02-28', beforeIssueId=null, nextIssueId=null, price=null, status=1, issueComplete=1, articleOrder=1, issueType=-1, specialIssue=null, createTime=1788926299563, creator='13701087609', updateTime=1788926573099, updator='13701087609', preIssue=null, nextIssue=null, articleTotal=null, ext={EN=IssueExt(id=1304415848316297970, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304414700964443026, language=EN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=), CN=IssueExt(id=1304415848316297971, tenantId=1146029695717560320, journalId=1302319053441957962, issueId=1304414700964443026, language=CN, specialIssueTitle=, coverIllustrator=null, specialIssueEditor=, specialIssueAbout=)}, issueFiles=null, downloadFileDto=null}, startPage=1481, endPage=1491, ext={EN=ArticleExt(id=1304414736213365562, articleId=1304414735911375672, tenantId=1146029695717560320, journalId=1302319053441957962, language=EN, title=Quality differences of Paeoniae Radix Alba from different producing areas based on HS-GC-MS and electronic sensory technology, columnId=null, journalTitle=Chinese Traditional and Herbal Drugs, columnName=null, runingTitle=null, highlight=null, articleAbstract=Objective: To compare the differences in color, taste and odor of Baishao (Paeoniae Radix Alba) from different producing areas, and provide a reference for the quality evaluation of Paeoniae Radix Alba. Methods The chromaticity, taste and odor of Paeoniae Radix Alba from different origins were determined by spectrophotometer; electronic tongue and electronic nose. The volatile components of Paeoniae Radix Alba from different origins were identified and relatively quantified by headspace gas chromatography-mass spectrometry (HS-GC-MS), and multivariate statistical analyses were carried out to search for the differential volatile components of Paeoniae Radix Alba from different origins; and a pearson correlation analysis was conducted on the differential volatile components of Paeoniae Radix Alba from different origins and the electronic nose to find the basis of its odor substance. Results Anhui Bozhou Paeoniae Radix Alba powder has the highest L* value, Shandong Caoxian Paeoniae Radix Alba powder has the highest a* and b* values, and the chromaticity value of Paeoniae Radix Alba powder from different places of origin varies significantly; the samples of Paeoniae Radix Alba from different places of origin can be clearly differentiated by the electronic tongue, and the differences in their flavour are mainly in the richness, astringency and saltiness; the differences in the odor are mainly in the W5S, W1S, W1W, W2S, W2W, W3S sensors, and the odor of the Paeoniae Radix Alba from Bozhou, Anhui Province has a unique odor which is clearly different from that of Paeoniae Radix Alba from Linan, Zhejiang Province, and Caoxian, Shandong Province. A total of 53 volatile components were identified by HS-GC-MS, and 22, 29 and 22 differential volatile components were screened between the samples of Paeoniae Radix Alba from Bozhou, Anhui and Linan, Zhejiang, Bozhou, Anhui and Caoxian, Shandong, and Linan, Zhejiang and Caoxian, Shandong, respectively, with 2-methylbutyraldehyde, 2-ethyl-5-methyltetrahydrofuran and furfural being the common differential component of Paeoniae Radix Alba in the three origins. A total of 17 components that caused differences in the odor of Paeoniae Radix Alba from different origins were identified through pearson correlation analysis. Conclusion The experiment can better distinguish the Paeoniae Radix Alba from different origins through the colourimeter, electronic nose and electronic tongue technology combined with HS-GC-MS, which can provide scientific basis for the identification and quality evaluation of Paeoniae Radix Alba from different origins., authors=ZOU Han, FENG Yu, SUN Mingyue, ZHAO Lixin, NIU Liying, authorsList=ZOU Han, FENG Yu, SUN Mingyue, ZHAO Lixin, NIU Liying, authorCompany=null, correspAuthors=null, authorNote=null, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=null, pdfFileSize=null, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=null), CN=ArticleExt(id=1304414736133673785, articleId=1304414735911375672, tenantId=1146029695717560320, journalId=1302319053441957962, language=CN, title=基于HS-GC-MS和电子感官技术研究不同产地白芍的质量差异, columnId=1304140203967410414, journalTitle=中草药, columnName=药材与资源, runingTitle=null, highlight=null, articleAbstract=目的 比较不同产地白芍Paeonia lactiflora的色、味、气的差异,为白芍药材的质量评价提供参考。方法 利用分光测色仪、电子舌、电子鼻测定不同产地白芍的色度、味道、气味信息;采用顶空气相色谱-质谱法(headspace gas chromatography-mass spectrometry,HS-GC-MS)对不同产地白芍的挥发性成分进行鉴定与相对定量,并对其进行多元统计分析,寻找不同产地白芍的差异挥发性成分;对不同产地白芍的差异挥发性成分与电子鼻进行Pearson相关分析,寻找其气味物质基础。结果 安徽亳州白芍粉末L*值最高,山东曹县白芍粉末a*值、b*值最高,不同产地白芍粉末色度值存在差异;通过电子舌可区分不同产地白芍样品,其味道差异主要体现在丰富性、涩味和咸味;气味差异主要体现在W5S、W1S、W1W、W2S、W2W、W3S传感器,安徽亳州白芍气味独特,与浙江临安、山东曹县产地白芍有明显区分。采用HS-GC-MS共鉴定出53个挥发性成分,筛选出安徽亳州与浙江临安、安徽亳州与山东曹县、浙江临安与山东曹县白芍样品间的差异挥发性成分分别是22、29、22个,其中2-甲基丁醛、2-ethyl-5-methyltetrahydrofuran、糠醛是3个产地白芍共有的差异性成分。通过Pearson相关分析确定引起不同产地白芍气味差异的17个成分。结论 通过色度仪、电子舌、电子鼻技术结合HS-GC-MS可较好地区分不同产地白芍,为不同产地白芍的鉴定和质量评价提供科学依据。, authors=邹涵1, 冯玉1,2,3, 孙名悦1, 赵立新4, 牛丽颖1,2,3, authorsList=邹涵, 冯玉, 孙名悦, 赵立新, 牛丽颖, authorCompany=1 河北中医药大学, 河北 石家庄 050200;
2 河北省中药配方颗粒技术创新中心, 河北 石家庄 050091;
3 中药材品质评价与标准化河北省工程研究中心, 河北 石家庄 050091;
4 河北省药品审评中心, 河北 石家庄 050033, correspAuthors=牛丽颖, authorNote=邹涵: 邹涵(2001—),女,硕士,研究方向为中药分析。Tel:17367889925 E-mail:YJS20232122@hebcm.edu.cn, correspAuthorsNote=null, copyrightStatement=null, copyrightOwner=null, extLink=null, articleAbsUrl=null, sourceXml=null, magXml=null, pdfUrl=null, pdf=BOgc2+sZ5/aH2UCDL/b4Tw==, pdfFileSize=2237900, pdfExtLink=null, richHtmlUrl=null, mobilePdfUrl=null, reviewReport=null, pdfFirstPage=null, abstractGraph=null, abstractGraphContent=null, abstractVideo=null, citation=null, cebUrl=null, magXmlContent=null, mapNumber=null, fund=河北省重点研发计划项目 (20372502D); 国家中医药管理局科技项目 (GZY-KJS-2023-030); 河北省自然科学基金项目 (H2022423335); 河北省中医药管理局科研计划项目 (2025064))}, authors=null, keywords=[Keyword(id=1304414736339194683, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414735911375672, language=CN, orderNo=1, keyword=白芍), Keyword(id=1304414736410497852, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414735911375672, language=CN, orderNo=2, keyword=挥发性成分), Keyword(id=1304414736511161149, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414735911375672, language=CN, orderNo=3, keyword=色度), Keyword(id=1304414736586658622, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414735911375672, language=CN, orderNo=4, keyword=电子鼻), Keyword(id=1304414736649573183, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414735911375672, language=CN, orderNo=5, keyword=电子舌), Keyword(id=1304414736737653568, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414735911375672, language=CN, orderNo=6, keyword=顶空气相色谱-质谱法), Keyword(id=1304414736838316865, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414735911375672, language=EN, orderNo=1, keyword=Paeoniae Radix Alba), Keyword(id=1304414736905425730, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414735911375672, language=EN, orderNo=2, keyword=volatile components), Keyword(id=1304414736964145987, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414735911375672, language=EN, orderNo=3, keyword=chromaticity), Keyword(id=1304414737052226372, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414735911375672, language=EN, orderNo=4, keyword=electronic nose), Keyword(id=1304414737119335237, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414735911375672, language=EN, orderNo=5, keyword=electronic tongue), Keyword(id=1304414737199027014, tenantId=1146029695717560320, journalId=1302319053441957962, articleId=1304414735911375672, language=EN, orderNo=6, keyword=HS-GC-MS)], refs=null, funds=null, companyList=null, figs=null, attaches=null, journal=Journal(id=1302309778002903112, delFlag=0, nameCn=中草药, nameEn=Chinese Traditional and Herbal Drugs, nameHistory1=null, nameHistory2=null, issn=0253-2670, eissn=null, cn=12-1108/R, coden=null, periodic=3, language=CN, oaType=null, ccby=null, superviseOffice=null, ownerOffice=null, pubOffice=null, editorOffice=null, officeType=null, aims=null, clcCode=null, officeProv=null, officeCity=null, officeAddr=null, officeZip=null, officeEmail=null, officePhone=null, editDirector=null, officeDirector=null, officeDirectorPhone=null, officeStaffNum=null, officeEmpNum=null, coverPicUrl=cGpSKCP11AF8PAOcTXYWfg==, journalPrice=null, startedYear=null, abbrevIsoEn=Chinese Traditional and Herbal Drugs, journalRemark=null, publicationField=null, createdTime=1788424446827, updatedTime=1788949289390, createdBy=18614031015, updatedBy=13041195026, firstLetterCn=Z, firstLetterEn=Z, subjectCode=Medical and Pharmaceutical Sciences, subjectName=null, subjectCodeEn=Medical and Pharmaceutical Sciences, subjectNameEn=null, picCn=cGpSKCP11AF8PAOcTXYWfg==, picEn=Xw//kxUC3ON4eHxev0QLhQ==, jcr=null, cjcr=null, exts=[JournalExt(id=1304511127375863983, language=CN, name=中草药, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949289411, updatedTime=1788949289411, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://www.tiprpress.com/zcy/author/login, submissionEditorUrl=https://www.tiprpress.com/zcy/editor/login, submissionReviewUrl=https://www.tiprpress.com/zcy/reviewer/login, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""}), JournalExt(id=1304511127442972848, language=EN, name=Chinese Traditional and Herbal Drugs, nameHistory1=null, nameHistory2=null, managedBy=, sponsoredBy=, publishedBy=, editorOffice=, officeProv=null, officeCity=null, officeAddr=, officeZip=, editDirector=, officeDirector=null, officePhone=null, coverPicUrl=null, journalRemark=, submitArticleUrl=null, websiteUrl=, createdTime=1788949289427, updatedTime=1788949289427, createdBy=13041195026, updatedBy=13041195026, submissionGuidelinesUrl=, submissionAuthorUrl=https://www.tiprpress.com/zcy/author/login, submissionEditorUrl=https://www.tiprpress.com/zcy/editor/login, submissionReviewUrl=https://www.tiprpress.com/zcy/reviewer/login, submissionCeEditorUrl=, submissionAeEditorUrl=, option={"copyright":""})], databaseList=null, tenantJournalId=1302319053441957962, websiteList=[Website(id=1302319176408912052, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1302319053441957962, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zcy/CN, language=CN, createTime=1788426687576, createBy=18614031015, updateTime=1788427346252, updateBy=18614031015, name=中草药-中文, tplId=1146099689490845704, title=中草药, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1302322043651904087, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=articleTextType, value=kx, createTime=1788427371180, updateTime=1788427371180, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043593183828, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=banner, value=null, createTime=1788427371166, updateTime=1788427371166, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043672875610, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=grayFlag, value=0, createTime=1788427371185, updateTime=1788427371185, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043584795219, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=logo, value=https://castjournals.cast.org.cn/joweb/zcy/CN/file/pic?fileId=uiD1gpiRqR++OLOz4iKzDg==, createTime=1788427371164, updateTime=1788427371164, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043689652828, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=minRunFlag, value=0, createTime=1788427371189, updateTime=1788427371189, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043643515478, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zcy/CN/file/pic, createTime=1788427371178, updateTime=1788427371178, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043681264219, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=silenceFlag, value=0, createTime=1788427371187, updateTime=1788427371187, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043601572437, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_cn_619/, createTime=1788427371168, updateTime=1788427371168, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043660292696, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=themeColor, value=null, createTime=1788427371182, updateTime=1788427371182, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322043668681305, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176408912052, code=themeStyle, value=null, createTime=1788427371184, updateTime=1788427371184, creator=18614031015, updator=18614031015)]), Website(id=1302319176715096246, webName=null, webTitle=null, webDomain=null, webCopyrigh=null, webIpcNo=null, seoTitle=null, seoKeywords=null, seoDescription=null, tenantJournalId=null, journalId=1302319053441957962, journalNameCn=null, journalNameEn=null, grayFlag=null, tenantId=1146029695717560320, platformId=null, journalGroupId=null, journalGroupNameCn=null, journalGroupNameEn=null, type=1, domain=https://castjournals.cast.org.cn/joweb/zcy/EN, language=EN, createTime=1788426687649, createBy=18614031015, updateTime=1788427341161, updateBy=18614031015, name=中草药-英文, tplId=1146101810881728533, title=Chinese Traditional and Herbal Drugs, delFlag=0, indexPage=/home, props=[WebsiteProps(id=1302322015206134340, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=articleTextType, value=kx, createTime=1788427364398, updateTime=1788427364398, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015185162817, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=banner, value=null, createTime=1788427364393, updateTime=1788427364393, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015227105863, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=grayFlag, value=0, createTime=1788427364403, updateTime=1788427364403, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015176774208, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=logo, value=https://castjournals.cast.org.cn/joweb/zcy/EN/file/pic?fileId=uiD1gpiRqR++OLOz4iKzDg==, createTime=1788427364391, updateTime=1788427364391, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015239688777, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=minRunFlag, value=0, createTime=1788427364406, updateTime=1788427364406, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015201940035, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=picServerUrl, value=https://castjournals.cast.org.cn/joweb/zcy/EN/file/pic, createTime=1788427364397, updateTime=1788427364397, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015235494472, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=silenceFlag, value=0, createTime=1788427364405, updateTime=1788427364405, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015193551426, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=staticResourcePath, value=https://castjournals.cast.org.cn/joweb/cast_kjdb_en_623/, createTime=1788427364395, updateTime=1788427364395, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015214522949, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=themeColor, value=null, createTime=1788427364400, updateTime=1788427364400, creator=18614031015, updator=18614031015), WebsiteProps(id=1302322015218717254, tenantId=1146029695717560320, journalId=null, journalGroupId=null, siteId=1302319176715096246, code=themeStyle, value=null, createTime=1788427364401, updateTime=1788427364401, creator=18614031015, updator=18614031015)])], journalTitle=中草药, weixinUrl=null, journalUrl=https://www.tiprpress.com/zcy, iacademicId=null, status=1, seqNo=null, journalTitleEn=Chinese Traditional and Herbal Drugs, journalPhotoCn=cGpSKCP11AF8PAOcTXYWfg==, journalPhotoEn=Xw//kxUC3ON4eHxev0QLhQ==, journalFirstLetter=Z, journalRecommend=null, journalNew=null, journalCollection=null, jcrJf=null, cjcrJf=null, jcrJfStr=null, cjcrJfStr=null, submissionFirstDecision=null, sciSubjectClassification=null, casSubjectClassification=null, citeScore=null, totalCitationFrequency=null, icpCode=null, psCode=null, advertisingLicenseCode=null, copyrightInformation=null, country=null, option=, provinceCode=null, provinceName=null, collectFlag=false, interPubPlatform=, interPubPlatformUrl=null), detailUrlCn=https://castjournals.cast.org.cn/joweb/zcy/CN/10.7501/j.issn.0253-2670.2026.04.024, detailUrlEn=https://castjournals.cast.org.cn/joweb/zcy/EN/10.7501/j.issn.0253-2670.2026.04.024, pdfUrlCn=https://castjournals.cast.org.cn/joweb/zcy/CN/PDF/10.7501/j.issn.0253-2670.2026.04.024, pdfUrlEn=https://castjournals.cast.org.cn/joweb/zcy/EN/PDF/10.7501/j.issn.0253-2670.2026.04.024, aliStartDate=null, aliEndDate=null, collectionFlag=false, citedCount=null, citedUrl=null, previewStatus=0, delFlag=0, hasFullText=0, orderTime=1788926307894, fullTextJson=null, articleText=null, reference=茹凯月, 仇婧玥, 宋厚盼, 等. 白芍的本草考证[J]. 中医药通报, 2023, 22(8): 46-51.
中国药典[S]. 一部. 2025: 157.
崔红倩, 迟宇昊, 申远. 白芍的化学成分和药理作用研究进展[J]. 新乡医学院学报, 2024, 41(3): 291-297.
王世新, 王秋艳, 李爽, 等. 白术-白芍药对的物质基础及作用机制研究进展[J]. 中草药, 2025, 56(7): 2582-2592.
杜倩倩, 张铁军, 谢冬梅, 等. 基于指纹图谱结合化学模式识别法对不同种质白芍质量评价[J]. 中草药, 2023, 54(10): 3292-3301.
赵淼, 包永睿, 王帅, 等. 基于“质-量”双标的白芍质量分析方法研究[J]. 中草药, 2023, 54(22): 7325-7330.
王秋艳, 王世新, 隋方宇, 等. 白芍活性成分、药理作用及成分变化的影响因素研究进展[J]. 中草药, 2025, 56(5): 1817-1829.
李秋晗, 张喜武, 闫广利, 等. 基于UPLC-Q-TOF-MSE结合多元统计方法的不同产地白芍药材质量评价[J]. 中草药, 2023, 54(7): 2243-2253.
彭嘉玉, 黄玉珍, 温佳文, 等. 基于HS-GC-MS和电子感官技术分析白芍不同炮制品的颜色、气味变化[J]. 中国实验方剂学杂志, 2024, 30(20): 141-150.
谢亚婷, 叶先文, 张金莲, 等. 基于颜色量化与HS-GC-MS技术探讨白芍炮制前后成分、颜色变化[J]. 时珍国医国药, 2022, 33(10): 2418-2421.
郑郁清, 郭静英, 康爱圆, 等. 基于色度-化学成分关联的蜜糠炒白芍质量控制研究[J]. 中草药, 2023, 54(2): 534-543.
鄢贵, 龚普阳, 张复中, 等. 基于CiteSpace和VOSviewer的白芍研究现状及研究热点可视化分析[J]. 中草药, 2024, 55(11): 3805-3815.
杨硕, 徐中利, 赵新芝, 等. 基于电子感官系统和GC-IMS技术的大黄饮片基原辨识研究[J]. 中国药房, 2024, 35(9): 1076-1081.
韩刚, 翟丽, 王炳强, 等. 高效液相色谱法测定盐酸班布特罗胶囊的含量[J]. 药物分析杂志, 2006, 26(9): 1323-1324.
吕仕超, 王云姣, 张婉勤, 等. 白芍总苷的心血管保护效应及其作用机制的研究进展[J]. 现代药物与临床, 2022, 37(1): 207-210.
柴金珍, 黄远英, 袁根良, 等. 无花果的药理作用研究进展[J]. 中成药, 2016, 38(8): 1805-1810.
宁二娟, 李晓, 王伟, 等. 不同陈化年份南阳艾叶挥发油成分测定及抗氧化活性研究[J]. 中药材, 2024, 47(6): 1415-1419.
陈佳梅, 黄世伟, 李莞, 等. ICP-MS测定川芎及其近缘药材中的24种有害元素和营养元素[J]. 中草药, 2025, 56(19): 7186-7199.
房敏, 赵冠宇, 李泉洋, 等. 经典名方四物汤化学成分、药理作用、临床应用研究进展及质量标志物预测分析[J]. 中华中医药学刊, 2024, 42(7): 154-161.
胡耶芳, 李晓, 刘子祯, 等. 滇白珠的化学成分、药理活性及质量控制研究进展[J]. 中成药, 2020, 42(1): 162-168.
李文璇. 路路通活性成分筛选及桃金娘烯醛和β-氧化石竹烯抑制NLRP3炎性小体治疗类风湿关节炎作用机制[D]. 沈阳: 中国医科大学, 2021.
何育佩, 郝二伟, 谢金玲, 等. 紫苏药理作用及其化学物质基础研究进展[J]. 中草药, 2018, 49(16): 3957-3968.
朱熙妍, 付露欣, 周文, 等. 丁香酚的药理作用研究进展[J]. 中医临床研究, 2024, 16(31): 128-133.
肖淑华, 李字棋, 胡国婷, 等. 白豆蔻化学成分、药理作用研究进展及其质量标志物的预测分析[J]. 中国医院药学杂志, 2024, 44(21): 2548-2556.
张树蓉, 赵宏苏, 佟沫儒, 等. 牡丹皮化学成分、药理作用及其质量标志物(Q-Marker)的预测分析[J]. 中草药, 2022, 53(16): 5215-5224.
仉瑜, 张洪兵, 郭虹, 等. 姜黄的研究进展及质量标志物(Q-Marker)的预测分析[J]. 中草药, 2021, 52(15): 4700-4710.)
收藏切换
基于HS-GC-MS和电子感官技术研究不同产地白芍的质量差异
收藏切换
PDF下载
中草药 | 药材与资源 2026,57(4): 1481-1491
收起
收藏切换
中草药 |药材与资源 2026 , 57 (4) : 1481 -1491
基于HS-GC-MS和电子感官技术研究不同产地白芍的质量差异
全屏
邹涵1, 冯玉1,2,3, 孙名悦1, 赵立新4, 牛丽颖1,2,3
作者信息
    1 河北中医药大学, 河北 石家庄 050200;
    2 河北省中药配方颗粒技术创新中心, 河北 石家庄 050091;
    3 中药材品质评价与标准化河北省工程研究中心, 河北 石家庄 050091;
    4 河北省药品审评中心, 河北 石家庄 050033
通讯作者:
牛丽颖
作者简介:
邹涵: 邹涵(2001—),女,硕士,研究方向为中药分析。Tel:17367889925 E-mail:YJS20232122@hebcm.edu.cn
Quality differences of Paeoniae Radix Alba from different producing areas based on HS-GC-MS and electronic sensory technology
  • ZOU Han, FENG Yu, SUN Mingyue, ZHAO Lixin, NIU Liying
  • Affiliations
    doi: 10.7501/j.issn.0253-2670.2026.04.024
    文章导航
    收藏切换
    目的 比较不同产地白芍Paeonia lactiflora的色、味、气的差异,为白芍药材的质量评价提供参考。方法 利用分光测色仪、电子舌、电子鼻测定不同产地白芍的色度、味道、气味信息;采用顶空气相色谱-质谱法(headspace gas chromatography-mass spectrometry,HS-GC-MS)对不同产地白芍的挥发性成分进行鉴定与相对定量,并对其进行多元统计分析,寻找不同产地白芍的差异挥发性成分;对不同产地白芍的差异挥发性成分与电子鼻进行Pearson相关分析,寻找其气味物质基础。结果 安徽亳州白芍粉末L*值最高,山东曹县白芍粉末a*值、b*值最高,不同产地白芍粉末色度值存在差异;通过电子舌可区分不同产地白芍样品,其味道差异主要体现在丰富性、涩味和咸味;气味差异主要体现在W5S、W1S、W1W、W2S、W2W、W3S传感器,安徽亳州白芍气味独特,与浙江临安、山东曹县产地白芍有明显区分。采用HS-GC-MS共鉴定出53个挥发性成分,筛选出安徽亳州与浙江临安、安徽亳州与山东曹县、浙江临安与山东曹县白芍样品间的差异挥发性成分分别是22、29、22个,其中2-甲基丁醛、2-ethyl-5-methyltetrahydrofuran、糠醛是3个产地白芍共有的差异性成分。通过Pearson相关分析确定引起不同产地白芍气味差异的17个成分。结论 通过色度仪、电子舌、电子鼻技术结合HS-GC-MS可较好地区分不同产地白芍,为不同产地白芍的鉴定和质量评价提供科学依据。
    白芍  /  挥发性成分  /  色度  /  电子鼻  /  电子舌  /  顶空气相色谱-质谱法
    Objective: To compare the differences in color, taste and odor of Baishao (Paeoniae Radix Alba) from different producing areas, and provide a reference for the quality evaluation of Paeoniae Radix Alba. Methods The chromaticity, taste and odor of Paeoniae Radix Alba from different origins were determined by spectrophotometer; electronic tongue and electronic nose. The volatile components of Paeoniae Radix Alba from different origins were identified and relatively quantified by headspace gas chromatography-mass spectrometry (HS-GC-MS), and multivariate statistical analyses were carried out to search for the differential volatile components of Paeoniae Radix Alba from different origins; and a pearson correlation analysis was conducted on the differential volatile components of Paeoniae Radix Alba from different origins and the electronic nose to find the basis of its odor substance. Results Anhui Bozhou Paeoniae Radix Alba powder has the highest L* value, Shandong Caoxian Paeoniae Radix Alba powder has the highest a* and b* values, and the chromaticity value of Paeoniae Radix Alba powder from different places of origin varies significantly; the samples of Paeoniae Radix Alba from different places of origin can be clearly differentiated by the electronic tongue, and the differences in their flavour are mainly in the richness, astringency and saltiness; the differences in the odor are mainly in the W5S, W1S, W1W, W2S, W2W, W3S sensors, and the odor of the Paeoniae Radix Alba from Bozhou, Anhui Province has a unique odor which is clearly different from that of Paeoniae Radix Alba from Linan, Zhejiang Province, and Caoxian, Shandong Province. A total of 53 volatile components were identified by HS-GC-MS, and 22, 29 and 22 differential volatile components were screened between the samples of Paeoniae Radix Alba from Bozhou, Anhui and Linan, Zhejiang, Bozhou, Anhui and Caoxian, Shandong, and Linan, Zhejiang and Caoxian, Shandong, respectively, with 2-methylbutyraldehyde, 2-ethyl-5-methyltetrahydrofuran and furfural being the common differential component of Paeoniae Radix Alba in the three origins. A total of 17 components that caused differences in the odor of Paeoniae Radix Alba from different origins were identified through pearson correlation analysis. Conclusion The experiment can better distinguish the Paeoniae Radix Alba from different origins through the colourimeter, electronic nose and electronic tongue technology combined with HS-GC-MS, which can provide scientific basis for the identification and quality evaluation of Paeoniae Radix Alba from different origins.
    Paeoniae Radix Alba  /  volatile components  /  chromaticity  /  electronic nose  /  electronic tongue  /  HS-GC-MS
    邹涵, 冯玉, 孙名悦, 赵立新, 牛丽颖. 基于HS-GC-MS和电子感官技术研究不同产地白芍的质量差异. 中草药, 2026 , 57 (4) : 1481 -1491 . DOI: 10.7501/j.issn.0253-2670.2026.04.024
    ZOU Han, FENG Yu, SUN Mingyue, ZHAO Lixin, NIU Liying. Quality differences of Paeoniae Radix Alba from different producing areas based on HS-GC-MS and electronic sensory technology[J]. Chinese Traditional and Herbal Drugs, 2026 , 57 (4) : 1481 -1491 . DOI: 10.7501/j.issn.0253-2670.2026.04.024

      河北省重点研发计划项目 (20372502D); 国家中医药管理局科技项目 (GZY-KJS-2023-030); 河北省自然科学基金项目 (H2022423335); 河北省中医药管理局科研计划项目 (2025064)

    参考文献 引证文献
    排序方式:
    茹凯月, 仇婧玥, 宋厚盼, 等. 白芍的本草考证[J]. 中医药通报, 2023, 22(8): 46-51.
    中国药典[S]. 一部. 2025: 157.
    崔红倩, 迟宇昊, 申远. 白芍的化学成分和药理作用研究进展[J]. 新乡医学院学报, 2024, 41(3): 291-297.
    王世新, 王秋艳, 李爽, 等. 白术-白芍药对的物质基础及作用机制研究进展[J]. 中草药, 2025, 56(7): 2582-2592.
    杜倩倩, 张铁军, 谢冬梅, 等. 基于指纹图谱结合化学模式识别法对不同种质白芍质量评价[J]. 中草药, 2023, 54(10): 3292-3301.
    赵淼, 包永睿, 王帅, 等. 基于“质-量”双标的白芍质量分析方法研究[J]. 中草药, 2023, 54(22): 7325-7330.
    王秋艳, 王世新, 隋方宇, 等. 白芍活性成分、药理作用及成分变化的影响因素研究进展[J]. 中草药, 2025, 56(5): 1817-1829.
    李秋晗, 张喜武, 闫广利, 等. 基于UPLC-Q-TOF-MSE结合多元统计方法的不同产地白芍药材质量评价[J]. 中草药, 2023, 54(7): 2243-2253.
    彭嘉玉, 黄玉珍, 温佳文, 等. 基于HS-GC-MS和电子感官技术分析白芍不同炮制品的颜色、气味变化[J]. 中国实验方剂学杂志, 2024, 30(20): 141-150.
    谢亚婷, 叶先文, 张金莲, 等. 基于颜色量化与HS-GC-MS技术探讨白芍炮制前后成分、颜色变化[J]. 时珍国医国药, 2022, 33(10): 2418-2421.
    郑郁清, 郭静英, 康爱圆, 等. 基于色度-化学成分关联的蜜糠炒白芍质量控制研究[J]. 中草药, 2023, 54(2): 534-543.
    鄢贵, 龚普阳, 张复中, 等. 基于CiteSpace和VOSviewer的白芍研究现状及研究热点可视化分析[J]. 中草药, 2024, 55(11): 3805-3815.
    杨硕, 徐中利, 赵新芝, 等. 基于电子感官系统和GC-IMS技术的大黄饮片基原辨识研究[J]. 中国药房, 2024, 35(9): 1076-1081.
    韩刚, 翟丽, 王炳强, 等. 高效液相色谱法测定盐酸班布特罗胶囊的含量[J]. 药物分析杂志, 2006, 26(9): 1323-1324.
    吕仕超, 王云姣, 张婉勤, 等. 白芍总苷的心血管保护效应及其作用机制的研究进展[J]. 现代药物与临床, 2022, 37(1): 207-210.
    柴金珍, 黄远英, 袁根良, 等. 无花果的药理作用研究进展[J]. 中成药, 2016, 38(8): 1805-1810.
    宁二娟, 李晓, 王伟, 等. 不同陈化年份南阳艾叶挥发油成分测定及抗氧化活性研究[J]. 中药材, 2024, 47(6): 1415-1419.
    陈佳梅, 黄世伟, 李莞, 等. ICP-MS测定川芎及其近缘药材中的24种有害元素和营养元素[J]. 中草药, 2025, 56(19): 7186-7199.
    房敏, 赵冠宇, 李泉洋, 等. 经典名方四物汤化学成分、药理作用、临床应用研究进展及质量标志物预测分析[J]. 中华中医药学刊, 2024, 42(7): 154-161.
    胡耶芳, 李晓, 刘子祯, 等. 滇白珠的化学成分、药理活性及质量控制研究进展[J]. 中成药, 2020, 42(1): 162-168.
    李文璇. 路路通活性成分筛选及桃金娘烯醛和β-氧化石竹烯抑制NLRP3炎性小体治疗类风湿关节炎作用机制[D]. 沈阳: 中国医科大学, 2021.
    何育佩, 郝二伟, 谢金玲, 等. 紫苏药理作用及其化学物质基础研究进展[J]. 中草药, 2018, 49(16): 3957-3968.
    朱熙妍, 付露欣, 周文, 等. 丁香酚的药理作用研究进展[J]. 中医临床研究, 2024, 16(31): 128-133.
    肖淑华, 李字棋, 胡国婷, 等. 白豆蔻化学成分、药理作用研究进展及其质量标志物的预测分析[J]. 中国医院药学杂志, 2024, 44(21): 2548-2556.
    张树蓉, 赵宏苏, 佟沫儒, 等. 牡丹皮化学成分、药理作用及其质量标志物(Q-Marker)的预测分析[J]. 中草药, 2022, 53(16): 5215-5224.
    仉瑜, 张洪兵, 郭虹, 等. 姜黄的研究进展及质量标志物(Q-Marker)的预测分析[J]. 中草药, 2021, 52(15): 4700-4710.
    2026年第57卷第4期
    PDF下载
    29
    7
    引用本文
    BibTeX
    文章信息
    doi: 10.7501/j.issn.0253-2670.2026.04.024
    • 接收时间:2025-10-02
    • 首发时间:2026-09-09
    补充材料
    相关文章
    文章信息
    作者
    出版历史
    • 收稿日期:2025-10-02
    基金
    作者信息
    参考文献
    分享链接
    https://castjournals.cast.org.cn/joweb/zcy/CN/10.7501/j.issn.0253-2670.2026.04.024
    分享至
    全文二维码

    扫描看全文

    引用本文
    BibTeX
    本文的引用情况
    2种不同金属材料的力学参数

    Family
    属数
    Number of
    genus
    种数
    Number of
    species
    占总种数比例
    Percentage of
    total species (%)

    Genus
    种数
    Number of
    species
    占总种数比例
    Percentage of total
    species (%)
    鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
    小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
    多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
    红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
    小菇属 Mycena 11 5.26
    光柄菇属 Pluteus 5 2.39
    红菇属 Russula 17 8.13
    栓菌属 Trametes 5 2.39
    关闭全屏